Blockade of CD40 ligand for intercellular communication reduces hypertension, placental oxidative stress, and AT1-AA in response to adoptive transfer of CD4+ t lymphocytes from RUPP rats

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 309, Issue 10, 2015, Pages R1243-R1250

  Cornelius, Denise C ^a   Castillo, Javier ^a   Porter, Justin ^a   Amaral, Lorena M ^a   Campbell, Nathan ^a   Paige, Adrienne ^a   Thomas, Alexia J ^a   Harmon, Ashlyn ^a   Cunningham, Mark W ^a   Wallace, Kedra ^a   Herse, Florian ^b   Wallukat, Gerd ^b   Dechend, Ralf ^b,c   LaMarca, Babbette ^a  

^a UNIVERSITY OF MISSISSIPPI SCHOOL OF MEDICINE   (United States)

^b MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^c Helios Klinikum   (Germany)

Author keywords

B cells; Hypertension; Preeclampsia; T cells

Indexed keywords

ANGIOTENSIN II; ANGIOTENSIN RECEPTOR; CD40 LIGAND; CD40 LIGAND MONOCLONAL ANTIBODY; ENDOTHELIN 1; REACTIVE OXYGEN METABOLITE; ANGIOTENSIN 1 RECEPTOR; CD40 ANTIGEN; MESSENGER RNA;

ADOPTIVE TRANSFER; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD ANALYSIS; BLOOD PRESSURE; CD4+ T LYMPHOCYTE; CELL COMMUNICATION; CONTROLLED STUDY; FEMALE; HYPERTENSION; INFLAMMATION; INTRAUTERINE PRESSURE; NONHUMAN; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PERFUSION PRESSURE; PLACENTA; PREECLAMPSIA; PREGNANCY; PRIORITY JOURNAL; PROTEIN BINDING; RAT; REDUCED UTERINE PERFUSION PRESSURE; SPLEEN; ANIMAL; GENE EXPRESSION REGULATION; GENETICS; ISCHEMIA; METABOLISM; PHYSIOLOGY; SPRAGUE DAWLEY RAT; TRANSPLANTATION; UTERUS; VASCULARIZATION;

ADOPTIVE TRANSFER; ANIMALS; ANTIGENS, CD40; CD4-POSITIVE T-LYMPHOCYTES; CELL COMMUNICATION; ENDOTHELIN-1; FEMALE; GENE EXPRESSION REGULATION; HYPERTENSION; ISCHEMIA; OXIDATIVE STRESS; PLACENTA; PREGNANCY; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; RECEPTOR, ANGIOTENSIN, TYPE 1; RNA, MESSENGER; UTERUS;

EID: 84947292752     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.00273.2015     Document Type: Article

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