Role of angiotensin II type i receptor agonistic autoantibodies (AT1-AA) in preeclampsia

Current Opinion in Pharmacology

Volumn 11, Issue 2, 2011, Pages 175-179

  Lamarca, Babbette ^a   Wallace, Kedra ^a   Granger, Joey ^a  

^a UNIVERSITY OF MISSISSIPPI MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN II; ANGIOTENSIN II TYPE 1 RECEPTOR AGONISTIC AUTOANTIBODY; ANGIOTENSINOGEN; AUTOANTIBODY; ENDOGLIN; ENDOTHELIN A RECEPTOR ANTAGONIST; IMMUNOGLOBULIN G3 ANTIBODY; LOSARTAN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VASCULOTROPIN RECEPTOR 1;

ANTIBODY PRODUCTION; ARTICLE; CARDIOVASCULAR RISK; HUMAN; HYPERTENSION; INTRAUTERINE PRESSURE; ISCHEMIA; MATERNAL HYPERTENSION; MEAN ARTERIAL PRESSURE; NONHUMAN; PATHOPHYSIOLOGY; PLACENTA PERFUSION; PLASMA RENIN ACTIVITY; PREECLAMPSIA; PRIORITY JOURNAL; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; RENOVASCULAR DISEASE;

EID: 79954420257     PISSN: 14714892     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.coph.2011.01.003     Document Type: Review

References (36)

1. J.M. Roberts, G. Pearson, J. Cutler, and M. Lindheimer Summary of the NHLBI working group on research on hypertension during pregnancy Hypertension 41 2003 437 445 (Pubitemid 36314613)
2. B. Sibai, G. Dekker, and M. Kupferminc Pre-eclampsia Lancet 365 2005 785 799 (Pubitemid 40311367)
3. B.M. Sibai, S. Caritis, and J. Hauth What we have learned about preeclampsia Semin Perinatol 27 2003 239 246 (Pubitemid 36828961)
4. J.M. Roberts, and K.Y. Lain Recent insights into the pathogenesis of pre-eclampsia Placenta 23 2002 359 372 (Pubitemid 41110499)
5. B.T. Alexander, S.E. Kassab, M.T. Miller, S.R. Abram, J.F. Reckelhoff, W.A. Bennett, and J.P. Granger Reduced uterine perfusion pressure during pregnancy in the rat is associated with increases in arterial pressure and changes in renal nitric oxide Hypertension 37 2001 1191 1195 (Pubitemid 32304024)
6. B.B. LaMarca, J. Gilbert, and J.P. Granger Recent progress toward the understanding of the pathophysiology of hypertenssion during preeclampsia Hypertension 51 2008 982 988 A recent review of the preeclampsia research literature. (Pubitemid 351398991)
7. C.C. Zhou, Y. Zhang, R.A. Irani, H. Zhang, T. Mi, E.J. Popek, M.J. Hicks, S.M. Ramin, R.E. Kellems, and Y. Xia Angiotensin receptor agonistic autoantibodies induce pre-eclampsia in pregnant mice Nat Med 14 2008 855 862 Paper showing that overexpression of AT1-AA in mice causes preeclampsia like phenotype.
8. B.T. Alexander, A.N. Rinewalt, K.L. Cockrell, M.B. Massey, W.A. Bennett, and J.P. Granger Endothelin type a receptor blockade attenuates the hypertension in response to chronic reductions in uterine perfusion pressure Hypertension 37 2001 485 489 (Pubitemid 32199016)
9. D.M. Shah Role of the renin-angiotensin system in the pathogenesis of preeclampsia Am J Physiol Renal Physiol 288 2005 F614 F625
10. Y. Xia, S.M. Ramin, and R.E. Kellems Potential roles of angiotensin receptor-activating autoantibody in the pathophysiology of preeclampsia Hypertension 50 2007 269 275 (Pubitemid 47205769)
11. G. Wallukat, V. Homuth, T. Fischer, C. Lindschau, B. Horstkamp, A. Jupner, E. Baur, E. Nissen, K. Vetter, and D. Neichel Patients with preeclampsia develop agonistic autoantibodies against the angiotensin AT1 receptor J Clin Investig 103 1999 945 952 Original finding that patients with preeclampsia develop agonistic autoantibodies against the angiotensin AT1 receptor. (Pubitemid 29169601)
12. Y. Xia, H. Wen, S. Bobst, M. Day, and R. Kellems Maternal autoantibodies from preeclamptic patients activate angiotensin receptors on human trophoblast cells Reprod Sci 10 2003 82 93 (Pubitemid 36184763)
13. Y. Xia, S. Ramin, and R. Kellems Potential roles of angiotensin receptor-activating autoantibody in the pathophysiology of preeclampsia Hypertension 50 2007 269 275 (Pubitemid 47205769)
14. C.A. Hubel, G. Wallukat, M. Wolf, F. Herse, A. Rajakumar, J.M. Roberts, N. Markovic, R. Thadhani, F.C. Luft, and R. Dechend Agonistic angiotenin II type I receptor autoantibodies in ostpartum women with a history of preeclampsia Hypertension 49 2007 612 617
15. B. LaMarca, W. Bennett, B. Alexander, K. Cockrell, and J. Granger Hypertension produced by reductions in uterine perfusion in the pregnant rat: role of tumor necrosis factor-alpha Hypertension 46 2005 1022 1025
16. B. Lamarca, G. Wallukat, M. Llinas, F. Herse, R. Dechend, and J. Granger Autoantibodies to the angiotensini type I receptor in response to placental ischemia and tumor necrosis factor alpha in pregnant rats Hypertension 52 2008 1168 1172 Study showing that placental ischemia and tumor necrosis factor alpha are important stimuli of autoantibodies to the angiotensini type I receptor in pregnant rats.
17. B. LaMarca, M. Parrish, L.F. Ray, S.R. Murphy, L. Roberts, P. Glover, G. WaHukat, K. Wenzel, K. Cockrell, and J.N. Martin Jr. Hypertension in response to autoantibodies to the angiotensin II type I receptor (AT1-AA) in pregnant rats: a role of endothelin-1 Hypertension 54 2009 905 909
18. R. Dechend, C. Viedt, D.N. Muller, B. Ugele, R.P. Brandes, G. Wallukat, J.K. Park, J. Janke, P. Barta, and J. Theuer AT1 receptor agonistic antibodies from preeclamptic patients stimulate NADPH oxidase Circulation 107 2003 1632 1639 (Pubitemid 36401560)
19. R. Dechend, V. Homuth, G. Wallukat, D.N. Müller, M. Krause, J. Dudenhausen, H. Haller, and F.C. Luft Agonistic antibodies directed at the angiotensin II, AT1 receptor in preeclampsia J Soc Gynecol Investig 13 2006 79 86 8 (Pubitemid 43155838)
20. T.M. Thway, S.G. Shlykov, M.C. Day, B.M. Sanborn, L.C. Gilstrap III, Y. Xia, and R.E. Kellems Antibodies from preeclamptic patients stimulate increased intracellular Ca2- mobilization through angiotensin receptor activation Circulation 110 2004 1612 1619
21. R. Dechend, P. Gratze, G. Wallukat, E. Shagdarsuren, R. Plehm, J.H. Brãsen, FiebelerA, SchneiderW, S. Caluwaerts, and L. Vercruysse Agonistic autoantibodies to the AT1 receptor in a transgeneic rat model of preeclampsia Hypertension 45 2005 742 746 (Pubitemid 40418375)
22. T. Walther, G. Wallukat, A. Jank, S. Bartel, H.P. Schuitheiss, R. Faber, and H. Stepan Angiotensin II type 1 receptor agonistic antibodies reflect fundamental alterations in the uteroplacental vasculature Hypertension 46 2005 1275 1279 (Pubitemid 43189723)
23. D. Dragun, D.N. Muller, J.H. Braseri, L. Fritsche, M. Nieminen-Kelhä, R. Dechend, U. Kintscher, B. Rudolph, J. Hoebeke, and D. Eckert Angiontensin II type-1 receptor activating anitbodies in renal-allograft rejection New Engl J Med 352 2005 558 569 (Pubitemid 40204669)
24. M.L. Fu, H. Herlitz, W. Schulze, G. Wallukat, P. Micke, P. Eftekhari, K.G. Sjogren, A. Hjalmarson, W. MullerEsterl, and J. Hoebeke Autoantibodies against the angiotensin receptor (AT1) in patients with hypertension J Hypertens 18 2000 945 953 (Pubitemid 30459497)
25. B. LaMarca, K. Wallace, F. Herse, G. Wallukat, A. Weimer, and R. Dechend Hypertension in response to placental ischemia during pregnancy: role of agonistic autoantibodies to the angiotensin II type I receptor (AT1-AA) Hypertension 56 2010 e56
26. M.R. Parrish, S.R. Murphy, S. Rutland, K. Wallace, K. Wenzel, G. Wallukat, S. Keiser, L.F. Ray, R. Dechend, and J.N. Martin The effect of immune factors, tumor necrosis factor-alpha, and agonistic autoantibodies to the angiotensin II Type I receptor on soluble fms-like tyrosine-1 and soluble endoglin production in response to hypertension during pregnancy Am J Hypertens 23 2010 911 916
27. F. Herse, S. Verlohren, K. Wenzel, J. Pape, D.N. Muller, S. Modrow, G. Wallukat, F.C. Luft, C.W.G. Redman, and R. Dechend Prevalence of agonistic autoantibodies against the angiotensin II type 1 receptor and soluble fms-like tyrosine kinase 1 in a gestational age-matched case study Hypertension 53 2009 393 398
28. K. Broliden, T. Tolfvenstam, and O. Norbeck Clinical aspects of parvovirus B19 infection J Int Med 260 2006 285 304 (Pubitemid 44370903)
29. B. Santner-Nanan, M.J. Peek, R. Khanam, L. Richarts, E. Zhu, B. Fazekas de St Groth, and R. Nanan Systemic increase in the ration between FoxP3+ and IL-17 producing CD4+ T cells in healthy pregnancy but not in preeclampsia J Immunol 183 2009 7023 7030
30. I. Sargent, A. Borzychowski, and C. Redman Immunoregulation in normal pregnancy and preeclampsia: an overview Reprod Biomed Online 13 2006 680 686 (Pubitemid 44760892)
31. J.R. Prins, H.M. Boelens, J. Heimweg, S. Van der Heide, A.E. Dubois, A.J. Van Oosterhout, and J.J. Erwich Preeclampsia is associated with lower percentages of regulatory T cells in maternal blood Hypertens Pregnancy 28 2009 300 311
32. A. Abbus Cellular and Molecular Immunology edn 5 2005 Elsevier Philadelphia
33. J. Cruse, and R. Lewis Illustrated Dictionary of Immunology edn 3 2009 CRC Press
34. B.T. Alexander, S.E. Kassab, M.T. Miller, S.R. Abram, J.F. Reckeihoff, W.A. Bennett, and J.P. Granger Reduced uterine perfusion pressure during pregnancy in the rat is associated with increases in arterial pressure and changes in renal nitric oxide Hypertension 37 2001 1191 1195 (Pubitemid 32304024)
35. J.P. Granger, B.B. LaMarca, K. Cockrell, M. Sedeek, C. Baizi, D. Chandler, and W. Bennett Reduced uterine perfusion pressure (RUPP) model for studying cardiovascular-renal dysfunction in response to placental ischemia Methods Mol Med 122 2006 383 392
36. B. LaMarca The role of immune activation in contributing to vascular dysfunction and the pathophysiology of hypertension during preeclampsia Minerva Ginecol 62 2010 105 120