Structural and Mechanistic Insights into the Latrophilin3-FLRT3 Complex that Mediates Glutamatergic Synapse Development

Structure

Volumn 23, Issue 9, 2015, Pages 1665-1677

  Ranaivoson, Fanomezana M ^a   Liu, Qun ^b   Martini, Francesca ^a   Bergami, Francesco ^a   Von Daake, Sventja ^a   Li, Sheng ^c   Lee, David ^c   Demeler, Borries ^d   Hendrickson, Wayne A ^b,e   Comoletti, Davide ^a,f  

^a CHILD HEALTH INSTITUTE OF NEW JERSEY   (United States)

^b NEW YORK STRUCTURAL BIOLOGY CENTER   (United States)

^c UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^d Mays Cancer Center at UT Health San Antonio   (United States)

^e Och Spine at New York Presbyterian Hospitals   (United States)

^f ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; FIBRONECTIN LEUCINE RICH REPEAT TRANSMEMBRANE 3 PROTEIN; LATROPHILIN3 PROTEIN; PROTEIN; UNCLASSIFIED DRUG; CALCIUM; FLRT3 PROTEIN, MOUSE; G PROTEIN COUPLED RECEPTOR; GLUTAMIC ACID; LPHN3 PROTEIN, MOUSE; MEMBRANE PROTEIN; RECEPTOR;

AMINO TERMINAL SEQUENCE; ARTICLE; BETA SHEET; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; CRYSTALLIZATION; DEUTERIUM HYDROGEN EXCHANGE; DIMERIZATION; DISSOCIATION CONSTANT; GLUTAMATERGIC SYNAPSE; GLYCOSYLATION; HUMAN; HUMAN CELL; HYDROGEN BOND; HYDROPHOBICITY; ISOTHERMAL TITRATION CALORIMETRY; MASS SPECTROMETRY; MOUSE; MUTATIONAL ANALYSIS; NONHUMAN; OLFACTOMEDIN DOMAIN; OLIGOMERIZATION; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; SEDIMENTATION RATE; SIZE EXCLUSION CHROMATOGRAPHY; STATIC ELECTRICITY; ULTRACENTRIFUGATION; WILD TYPE; ANIMAL; BINDING SITE; CHEMICAL PHENOMENA; CHEMISTRY; HEK293 CELL LINE; METABOLISM; MOLECULAR MODEL; PROTEIN SECONDARY STRUCTURE; SYNAPSE; X RAY CRYSTALLOGRAPHY;

ANIMALS; BINDING SITES; CALCIUM; CRYSTALLOGRAPHY, X-RAY; GLUTAMIC ACID; HEK293 CELLS; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MEMBRANE GLYCOPROTEINS; MICE; MODELS, MOLECULAR; PROTEIN STRUCTURE, SECONDARY; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, PEPTIDE; SYNAPSES;

EID: 84947046182     PISSN: 09692126     EISSN: 18784186     Source Type: Journal    
DOI: 10.1016/j.str.2015.06.022     Document Type: Article

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