메뉴 건너뛰기




Volumn 39, Issue 12, 2015, Pages 2503-2509

Mechano growth factor-E regulates apoptosis and inflammatory responses in fibroblast-like synoviocytes of knee osteoarthritis

Author keywords

Apoptosis; ER stress; Fibroblast like synoviocytes; Inflammatory cytokines; Lysyl oxidase; MGF E peptide; Osteoarthritis

Indexed keywords

GROWTH FACTOR; INTERLEUKIN 1BETA; MECHANO GROWTH FACTOR E; PROTEIN LYSINE 6 OXIDASE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; 3-(4,5-DIMETHYLTHIAZOL-2-YL)-5-(3-CARBOXYMETHOXYPHENYL)-2-(4-SULFOPHENYL)-2H-TETRAZOLIUM; 5-ETHYNYL-2'-DEOXYURIDINE; CYTOKINE; DEOXYURIDINE; MECHANO-GROWTH FACTOR E, HUMAN; SOMATOMEDIN C; TETRAZOLIUM; THIAZOLE DERIVATIVE;

EID: 84947044590     PISSN: 03412695     EISSN: 14325195     Source Type: Journal    
DOI: 10.1007/s00264-015-2974-5     Document Type: Article
Times cited : (16)

References (41)
  • 1
    • 77649241985 scopus 로고    scopus 로고
    • LXR modulation blocks prostaglandin E2 production and matrix degradation in cartilage and alleviates pain in a rat osteoarthritis model
    • COI: 1:CAS:528:DC%2BC3cXjtFamsr4%3D, PID: 20133709
    • Li N, Rivéra-Bermúdez MA, Zhang M et al (2010) LXR modulation blocks prostaglandin E2 production and matrix degradation in cartilage and alleviates pain in a rat osteoarthritis model. Proc Natl Acad Sci U S A 107:3734–3739
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 3734-3739
    • Li, N.1    Rivéra-Bermúdez, M.A.2    Zhang, M.3
  • 2
    • 84863206376 scopus 로고    scopus 로고
    • Synovial fluid from patients with early osteoarthritis modulates fibroblast-like synoviocyte responses to toll-like receptor 4 and toll-like receptor 2 ligands via soluble CD14
    • COI: 1:CAS:528:DC%2BC38XptFCgu74%3D, PID: 22492243
    • Nair A, Kanda V, Bush-Joseph C et al (2012) Synovial fluid from patients with early osteoarthritis modulates fibroblast-like synoviocyte responses to toll-like receptor 4 and toll-like receptor 2 ligands via soluble CD14. Arthritis Rheum 64:2268–2277
    • (2012) Arthritis Rheum , vol.64 , pp. 2268-2277
    • Nair, A.1    Kanda, V.2    Bush-Joseph, C.3
  • 3
    • 84855968514 scopus 로고    scopus 로고
    • High concentrations of hydrogen sulphide elevate the expression of a series of pro-inflammatory genes in fibroblast-like synoviocytes derived from rheumatoid and osteoarthritis patients
    • COI: 1:CAS:528:DC%2BC3MXhs1CitbnO, PID: 22015639
    • Kloesch B, Liszt M, Krehan D et al (2012) High concentrations of hydrogen sulphide elevate the expression of a series of pro-inflammatory genes in fibroblast-like synoviocytes derived from rheumatoid and osteoarthritis patients. Immunol Lett 141:197–203
    • (2012) Immunol Lett , vol.141 , pp. 197-203
    • Kloesch, B.1    Liszt, M.2    Krehan, D.3
  • 4
    • 84866513760 scopus 로고    scopus 로고
    • Interleukin-18-induced inflammatory responses in synoviocytes and chondrocytes from osteoarthritic patients
    • COI: 1:CAS:528:DC%2BC38XhsFKmtL7L, PID: 22825306
    • Fu Z, Liu P, Yang D et al (2012) Interleukin-18-induced inflammatory responses in synoviocytes and chondrocytes from osteoarthritic patients. Int J Mol Med 30:805–810
    • (2012) Int J Mol Med , vol.30 , pp. 805-810
    • Fu, Z.1    Liu, P.2    Yang, D.3
  • 5
    • 33947532213 scopus 로고    scopus 로고
    • Unfolded protein response: its role in physiology and physiopathology
    • Foufelle F, Ferre P (2007) Unfolded protein response: its role in physiology and physiopathology. Med Sci (Paris) 23:291–296
    • (2007) Med Sci (Paris) , vol.23 , pp. 291-296
    • Foufelle, F.1    Ferre, P.2
  • 6
    • 84880641508 scopus 로고    scopus 로고
    • Evolution of the unfolded protein response
    • COI: 1:CAS:528:DC%2BC3sXisVSqtL0%3D, PID: 23369734
    • Hollien J (2013) Evolution of the unfolded protein response. Biochim Biophys Acta 1833:2458–2463
    • (2013) Biochim Biophys Acta , vol.1833 , pp. 2458-2463
    • Hollien, J.1
  • 7
    • 77949273353 scopus 로고    scopus 로고
    • Modulation of the unfolded protein response in prostate cancer cells by antibody-directed against the carboxyl-terminal domain of GRP78
    • COI: 1:CAS:528:DC%2BC3cXhtlSjsr8%3D, PID: 20091233
    • Misra UK, Pizzo SV (2010) Modulation of the unfolded protein response in prostate cancer cells by antibody-directed against the carboxyl-terminal domain of GRP78. Apoptosis 15:173–182
    • (2010) Apoptosis , vol.15 , pp. 173-182
    • Misra, U.K.1    Pizzo, S.V.2
  • 8
    • 79958033194 scopus 로고    scopus 로고
    • Modulating stress responses by the UPRosome: a matter of life and death
    • COI: 1:CAS:528:DC%2BC3MXnsVOqs7c%3D
    • Woehlbier U, Hetz C (2011) Modulating stress responses by the UPRosome: a matter of life and death. Trends BiochemSci 36:329–337
    • (2011) Trends BiochemSci , vol.36 , pp. 329-337
    • Woehlbier, U.1    Hetz, C.2
  • 9
    • 31444449462 scopus 로고    scopus 로고
    • Role of the unfolded protein response in cell death
    • COI: 1:CAS:528:DC%2BD28XovFygtQ%3D%3D, PID: 16374548
    • Kim R, Emi M, Tanabe K et al (2006) Role of the unfolded protein response in cell death. Apoptosis 11:5–13
    • (2006) Apoptosis , vol.11 , pp. 5-13
    • Kim, R.1    Emi, M.2    Tanabe, K.3
  • 10
    • 84899645950 scopus 로고    scopus 로고
    • Activated macrophage-like synoviocytes are resistant to endoplasmic reticulum stress-induced apoptosis in antigen-induced arthritis
    • COI: 1:CAS:528:DC%2BC2cXhsV2itL0%3D, PID: 24468888
    • Feng LJ, Jiang TC, Zhou CY et al (2014) Activated macrophage-like synoviocytes are resistant to endoplasmic reticulum stress-induced apoptosis in antigen-induced arthritis. Inflamm Res 63:335–346
    • (2014) Inflamm Res , vol.63 , pp. 335-346
    • Feng, L.J.1    Jiang, T.C.2    Zhou, C.Y.3
  • 11
    • 24044511547 scopus 로고    scopus 로고
    • Mechanical signals, IGF-I gene splicing, and muscle adaptation
    • COI: 1:CAS:528:DC%2BD2MXpslSmtbc%3D
    • Goldspink G (2005) Mechanical signals, IGF-I gene splicing, and muscle adaptation. Physiology (Bethesda) 20:232–238
    • (2005) Physiology (Bethesda) , vol.20 , pp. 232-238
    • Goldspink, G.1
  • 12
    • 34247187973 scopus 로고    scopus 로고
    • Insulin-like growth factor-1 isoform mRNA expression in women with endometriosis: eutopic endometrium versus endometriotic cyst
    • COI: 1:CAS:528:DC%2BD2sXjtlajt7k%3D, PID: 17308170
    • Milingos D, Katopodis H, Milingos S et al (2006) Insulin-like growth factor-1 isoform mRNA expression in women with endometriosis: eutopic endometrium versus endometriotic cyst. Ann N Y Acad Sci 1092:434–439
    • (2006) Ann N Y Acad Sci , vol.1092 , pp. 434-439
    • Milingos, D.1    Katopodis, H.2    Milingos, S.3
  • 13
    • 84884192210 scopus 로고    scopus 로고
    • Evidence for the possible biological significance of the igf-1 gene alternative splicing in prostate cancer
    • Philippou A, Armakolas A, Koutsilieris M (2013) Evidence for the possible biological significance of the igf-1 gene alternative splicing in prostate cancer. Front Endocrinol (Lausanne) 4:31
    • (2013) Front Endocrinol (Lausanne) , vol.4 , pp. 31
    • Philippou, A.1    Armakolas, A.2    Koutsilieris, M.3
  • 14
    • 84881360817 scopus 로고    scopus 로고
    • IGF-IEc expression is associated with advanced clinical and pathological stage of prostate cancer
    • COI: 1:CAS:528:DC%2BC3sXhtVGltrrO, PID: 23749893
    • Savvani A, Petraki C, Msaouel P et al (2013) IGF-IEc expression is associated with advanced clinical and pathological stage of prostate cancer. Anticancer Res 33:2441–2445
    • (2013) Anticancer Res , vol.33 , pp. 2441-2445
    • Savvani, A.1    Petraki, C.2    Msaouel, P.3
  • 15
    • 58149512066 scopus 로고    scopus 로고
    • Mechano-growth factor, an IGF-I splice variant, rescues motoneurons and improves muscle function in SOD1 (G93A) mice
    • COI: 1:CAS:528:DC%2BD1MXmvVemsg%3D%3D, PID: 19038252
    • Riddoch-Contreras J, Yang SY, Dick JR et al (2009) Mechano-growth factor, an IGF-I splice variant, rescues motoneurons and improves muscle function in SOD1 (G93A) mice. Exp Neurol 215:281–289
    • (2009) Exp Neurol , vol.215 , pp. 281-289
    • Riddoch-Contreras, J.1    Yang, S.Y.2    Dick, J.R.3
  • 16
    • 77149130495 scopus 로고    scopus 로고
    • Minireview: mechano-growth factor: a putative product of IGF-I gene expression involved in tissue repair and regeneration
    • COI: 1:CAS:528:DC%2BC3cXjvVKqs7s%3D, PID: 20130113
    • Matheny RW Jr, Nindl BC, Adamo ML (2010) Minireview: mechano-growth factor: a putative product of IGF-I gene expression involved in tissue repair and regeneration. Endocrinology 151:865–875
    • (2010) Endocrinology , vol.151 , pp. 865-875
    • Matheny, R.W.1    Nindl, B.C.2    Adamo, M.L.3
  • 17
    • 27744494888 scopus 로고    scopus 로고
    • A strong neuroprotective effect of the autonomous C-terminal peptide of IGF-1 Ec (MGF) in brain ischemia
    • COI: 1:CAS:528:DC%2BD2MXht1emtrvK, PID: 16144956
    • Dluzniewska J, Sarnowska A, Beręsewicz M et al (2005) A strong neuroprotective effect of the autonomous C-terminal peptide of IGF-1 Ec (MGF) in brain ischemia. FASEB J 19:1896–1898
    • (2005) FASEB J , vol.19 , pp. 1896-1898
    • Dluzniewska, J.1    Sarnowska, A.2    Beręsewicz, M.3
  • 18
    • 0038457273 scopus 로고    scopus 로고
    • Muscle satellite (stem) cell activation during local tissue injury and repair
    • COI: 1:CAS:528:DC%2BD3sXmsFGntrk%3D, PID: 12892408
    • Hill M, Wernig A, Goldspink G (2003) Muscle satellite (stem) cell activation during local tissue injury and repair. J Anat 203:89–99
    • (2003) J Anat , vol.203 , pp. 89-99
    • Hill, M.1    Wernig, A.2    Goldspink, G.3
  • 19
    • 33750604610 scopus 로고    scopus 로고
    • The MGF expression of osteoblasts in response to mechanical overload
    • COI: 1:CAS:528:DC%2BD28Xht1Sjs7nK, PID: 16934742
    • Tang LL, Xian CY, Wang YL (2006) The MGF expression of osteoblasts in response to mechanical overload. Arch Oral Biol 51:1080–1085
    • (2006) Arch Oral Biol , vol.51 , pp. 1080-1085
    • Tang, L.L.1    Xian, C.Y.2    Wang, Y.L.3
  • 20
    • 78149414568 scopus 로고    scopus 로고
    • Migration and proliferation of human mesenchymal stem cells is stimulated by different regions of the mechano-growth factor prohormone
    • COI: 1:CAS:528:DC%2BC3cXhtlyktbvI, PID: 20875825
    • Collins JM, Goldspink PH, Russell B (2010) Migration and proliferation of human mesenchymal stem cells is stimulated by different regions of the mechano-growth factor prohormone. J Mol Cell Cardiol 49:1042–1045
    • (2010) J Mol Cell Cardiol , vol.49 , pp. 1042-1045
    • Collins, J.M.1    Goldspink, P.H.2    Russell, B.3
  • 21
    • 84893975930 scopus 로고    scopus 로고
    • Mechano growth factor E peptide regulates migration and differentiation of bone marrow mesenchymal stem cells
    • COI: 1:CAS:528:DC%2BC2cXmslGmtL8%3D, PID: 24323763
    • Cui H, Yi Q, Feng J et al (2014) Mechano growth factor E peptide regulates migration and differentiation of bone marrow mesenchymal stem cells. J Mol Endocrinol 52:111–120
    • (2014) J Mol Endocrinol , vol.52 , pp. 111-120
    • Cui, H.1    Yi, Q.2    Feng, J.3
  • 22
    • 37049026520 scopus 로고    scopus 로고
    • Mechano-growth factor reduces loss of cardiac function in acute myocardial infarction
    • PID: 17581790
    • Carpenter V, Matthews K, Devlin G et al (2008) Mechano-growth factor reduces loss of cardiac function in acute myocardial infarction. Heart Lung Circ 17:33–39
    • (2008) Heart Lung Circ , vol.17 , pp. 33-39
    • Carpenter, V.1    Matthews, K.2    Devlin, G.3
  • 23
    • 84892582312 scopus 로고    scopus 로고
    • Mechano-growth factor peptide, the COOH terminus of unprocessed insulin-like growth factor 1, has no apparent effect on myoblasts or primary muscle stem cells
    • COI: 1:CAS:528:DC%2BC2cXitlejsr8%3D, PID: 24253050
    • Fornaro M, Hinken AC, Needle S et al (2014) Mechano-growth factor peptide, the COOH terminus of unprocessed insulin-like growth factor 1, has no apparent effect on myoblasts or primary muscle stem cells. Am J Physiol Endocrinol Metab 306:E150–E156
    • (2014) Am J Physiol Endocrinol Metab , vol.306 , pp. E150-E156
    • Fornaro, M.1    Hinken, A.C.2    Needle, S.3
  • 24
    • 10044294801 scopus 로고    scopus 로고
    • Mechanical signals and IGF-I gene splicing in vitro in relation to development of skeletalmuscle
    • COI: 1:CAS:528:DC%2BD2cXhtVOlsb7K, PID: 15389530
    • Cheema U, Brown R, Mudera V et al (2005) Mechanical signals and IGF-I gene splicing in vitro in relation to development of skeletalmuscle. J Cell Physiol 202:67–75
    • (2005) J Cell Physiol , vol.202 , pp. 67-75
    • Cheema, U.1    Brown, R.2    Mudera, V.3
  • 25
    • 84887417597 scopus 로고    scopus 로고
    • Mechano-growth factor induces migration of rat mesenchymal stem cells by altering its mechanical properties and activating ERK pathway
    • COI: 1:CAS:528:DC%2BC3sXhs12ksL7O, PID: 24140053
    • Wu J, Wu K, Lin F et al (2013) Mechano-growth factor induces migration of rat mesenchymal stem cells by altering its mechanical properties and activating ERK pathway. Biochem Biophys Res Commun 441:202–207
    • (2013) Biochem Biophys Res Commun , vol.441 , pp. 202-207
    • Wu, J.1    Wu, K.2    Lin, F.3
  • 26
    • 84868283442 scopus 로고    scopus 로고
    • Age-related loss of muscle mass and strength
    • PID: 22506111
    • Goldspink G (2012) Age-related loss of muscle mass and strength. J Aging Res 2012:158279
    • (2012) J Aging Res , vol.2012 , pp. 158279
    • Goldspink, G.1
  • 27
    • 79955772674 scopus 로고    scopus 로고
    • Mechano-growth factor E peptide (MGF-E), derived fromanisform of IGF-1, activates human muscle progenitor cells and induces an increase in their fusion potential at different ages
    • COI: 1:CAS:528:DC%2BC3MXmtFejtrs%3D, PID: 21354439
    • Kandalla PK, Goldspink G, Butler-Browne G et al (2011) Mechano-growth factor E peptide (MGF-E), derived fromanisform of IGF-1, activates human muscle progenitor cells and induces an increase in their fusion potential at different ages. Mech Ageing Dev 132:154–162
    • (2011) Mech Ageing Dev , vol.132 , pp. 154-162
    • Kandalla, P.K.1    Goldspink, G.2    Butler-Browne, G.3
  • 28
    • 74449093772 scopus 로고    scopus 로고
    • Changes in the expression of insulin-like growth factor 1 variants in the postnatal brain development and in neonatal hypoxia-ischaemia
    • COI: 1:CAS:528:DC%2BC3cXhtVKhurg%3D, PID: 19766709
    • Beresewicz M, Majewska M, Makarewicz D et al (2010) Changes in the expression of insulin-like growth factor 1 variants in the postnatal brain development and in neonatal hypoxia-ischaemia. Int J Dev Neurosci 28:91–97
    • (2010) Int J Dev Neurosci , vol.28 , pp. 91-97
    • Beresewicz, M.1    Majewska, M.2    Makarewicz, D.3
  • 29
    • 34848851582 scopus 로고    scopus 로고
    • Neuroprotective effects of short peptides derived from the insulin-like growth factor 1
    • Go´recki DC, Beresewicz M, Zabłocka B (2007) Neuroprotective effects of short peptides derived from the insulin-like growth factor 1. NeurochemInt 50:451–458
    • (2007) NeurochemInt , vol.50 , pp. 451-458
    • Go´recki, D.C.1    Beresewicz, M.2    Zabłocka, B.3
  • 30
    • 0038653361 scopus 로고    scopus 로고
    • Pathophysiological mechanisms in osteoarthritis lead to novel therapeutic strategies
    • PID: 12784040
    • Malemud CJ, Islam N, Haqqi TM (2003) Pathophysiological mechanisms in osteoarthritis lead to novel therapeutic strategies. Cells Tissues Organs 174:34–48
    • (2003) Cells Tissues Organs , vol.174 , pp. 34-48
    • Malemud, C.J.1    Islam, N.2    Haqqi, T.M.3
  • 31
    • 0028910233 scopus 로고
    • Lysyl oxidase and Maillard reaction-mediated crosslinks in aging and osteoarthritic rabbit cartilage
    • COI: 1:CAS:528:DyaK2MXktlylu7k%3D, PID: 7853094
    • Pokharna HK, Monnier V, Boja B et al (1995) Lysyl oxidase and Maillard reaction-mediated crosslinks in aging and osteoarthritic rabbit cartilage. J Orthop Res 13:13–21
    • (1995) J Orthop Res , vol.13 , pp. 13-21
    • Pokharna, H.K.1    Monnier, V.2    Boja, B.3
  • 32
    • 84858795786 scopus 로고    scopus 로고
    • Up-regulation expressions oflysyl oxidase family in anterior cruciate ligament and medial collateral ligament fibroblasts induced by transforming growth factor-beta
    • PID: 21674292
    • Xie J, Jiang JH, Zhang YJ et al (2011) Up-regulation expressions oflysyl oxidase family in anterior cruciate ligament and medial collateral ligament fibroblasts induced by transforming growth factor-beta. Int Orthop 36:207–213
    • (2011) Int Orthop , vol.36 , pp. 207-213
    • Xie, J.1    Jiang, J.H.2    Zhang, Y.J.3
  • 33
    • 0033555305 scopus 로고    scopus 로고
    • Coexpression of the lysyloxidase-like gene (LOXL) and the gene encoding type III procollagen in induced liver fibrosis
    • PID: 10022501
    • Kim YH, Peyrol S, So CK et al (1999) Coexpression of the lysyloxidase-like gene (LOXL) and the gene encoding type III procollagen in induced liver fibrosis. J Cell Biochem 72:181–188
    • (1999) J Cell Biochem , vol.72 , pp. 181-188
    • Kim, Y.H.1    Peyrol, S.2    So, C.K.3
  • 34
    • 0033617456 scopus 로고    scopus 로고
    • The LOXL2 gene encodes a new lysyl oxidase-like protein and is expressed at high levels in reproductive tissues
    • COI: 1:CAS:528:DyaK1MXjtFGntro%3D
    • Jourdan-Le Saux C, Tronecker H, Bogic L et al (1999) The LOXL2 gene encodes a new lysyl oxidase-like protein and is expressed at high levels in reproductive tissues. J Cell Biochem 274:12939–12944
    • (1999) J Cell Biochem , vol.274 , pp. 12939-12944
    • Jourdan-Le Saux, C.1    Tronecker, H.2    Bogic, L.3
  • 35
    • 0035368087 scopus 로고    scopus 로고
    • Central nervous system, uterus, heart, and leukocyte expression of theLOXL3 gene, encoding a novel lysyl oxidase-like protein
    • COI: 1:CAS:528:DC%2BD3MXjvFCjs7k%3D, PID: 11386757
    • Jourdan-Le Saux C, Tomsche A, Ujfalusi A et al (2001) Central nervous system, uterus, heart, and leukocyte expression of theLOXL3 gene, encoding a novel lysyl oxidase-like protein. Genomics 74:211–218
    • (2001) Genomics , vol.74 , pp. 211-218
    • Jourdan-Le Saux, C.1    Tomsche, A.2    Ujfalusi, A.3
  • 36
    • 0034749471 scopus 로고    scopus 로고
    • A novel human lysyloxidase-like gene (LOXL4) on chromosome 10q24 has an altered scavenger receptor cysteine rich domain
    • COI: 1:CAS:528:DC%2BD3MXnvFGjurw%3D
    • Asuncion L, Fogelgren B, Fong KSK et al (2001) A novel human lysyloxidase-like gene (LOXL4) on chromosome 10q24 has an altered scavenger receptor cysteine rich domain. Matris Biol 20:487–491
    • (2001) Matris Biol , vol.20 , pp. 487-491
    • Asuncion, L.1    Fogelgren, B.2    Fong, K.S.K.3
  • 37
    • 33750437433 scopus 로고    scopus 로고
    • Lysyl oxidase: an oxidative enzyme and effector of cell function
    • COI: 1:CAS:528:DC%2BD28XhtFyrtrrF, PID: 16909208
    • Lucero HA, Kagan HM (2006) Lysyl oxidase: an oxidative enzyme and effector of cell function. Cell Mol Life Sci 63:2304–2316
    • (2006) Cell Mol Life Sci , vol.63 , pp. 2304-2316
    • Lucero, H.A.1    Kagan, H.M.2
  • 38
    • 0027292694 scopus 로고
    • Cytokines and inflammation in cartilage degradation
    • COI: 1:STN:280:DyaK2c%2Fitlaqsw%3D%3D, PID: 8210574
    • Pelletier JP, DiBattista JA, Roughley P et al (1993) Cytokines and inflammation in cartilage degradation. Rheum Dis Clin North Am 19:545–568
    • (1993) Rheum Dis Clin North Am , vol.19 , pp. 545-568
    • Pelletier, J.P.1    DiBattista, J.A.2    Roughley, P.3
  • 39
    • 84919383614 scopus 로고    scopus 로고
    • Inhibition of transient receptor potential melastatin 7 (TRPM7) channel induces RA FLS apoptosis through endoplasmic reticulum (ER) stress
    • PID: 24733250
    • Li X, Wang X, Wang Y et al (2014) Inhibition of transient receptor potential melastatin 7 (TRPM7) channel induces RA FLS apoptosis through endoplasmic reticulum (ER) stress. Clin Rheumatol 33:1565–1574
    • (2014) Clin Rheumatol , vol.33 , pp. 1565-1574
    • Li, X.1    Wang, X.2    Wang, Y.3
  • 40
    • 78649275143 scopus 로고    scopus 로고
    • TNF-alpha induced aquaporin 9 in synoviocytes from patients with OA-and RA
    • COI: 1:CAS:528:DC%2BC3cXkvFKktrg%3D
    • Nagahara M, Waguri-Nagaya Y, Yamagami T et al (2010) TNF-alpha induced aquaporin 9 in synoviocytes from patients with OA-and RA. Rheumatology (Oxford) 49:898–906
    • (2010) Rheumatology (Oxford) , vol.49 , pp. 898-906
    • Nagahara, M.1    Waguri-Nagaya, Y.2    Yamagami, T.3
  • 41
    • 33846815065 scopus 로고    scopus 로고
    • The role of synovial macrophages and macrophage-produced cytokines in driving aggrecanases, matrix metalloproteinases, and other destructive and inflammatory responses in osteoarthritis
    • PID: 17177994
    • Bondeson J, Wainwright SD, Lauder S et al (2006) The role of synovial macrophages and macrophage-produced cytokines in driving aggrecanases, matrix metalloproteinases, and other destructive and inflammatory responses in osteoarthritis. Arthritis Res Ther 8:R187
    • (2006) Arthritis Res Ther , vol.8 , pp. R187
    • Bondeson, J.1    Wainwright, S.D.2    Lauder, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.