AKT1-mediated Lamin A/C degradation is required for nuclear degradation and normal epidermal terminal differentiation

Cell Death and Differentiation

Volumn 22, Issue 12, 2015, Pages 2123-2132

  Naeem, A S ^a   Zhu, Y ^a   Di, W L ^a   Marmiroli, S ^b   O'Shaughnessy, R F L ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN 2; CYTOKERATIN 1; CYTOKERATIN 10; DEOXYRIBONUCLEASE I; FILAGGRIN; LAMIN A; LAMIN C; LORICRIN; PROTEIN KINASE B; SHORT HAIRPIN RNA; SMAD1 PROTEIN; AKT1 PROTEIN, MOUSE; BMP2 PROTEIN, MOUSE; INTERMEDIATE FILAMENT PROTEIN; MEMBRANE PROTEIN; SMALL INTERFERING RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; ATOPIC DERMATITIS; CELL CULTURE; CELL DIFFERENTIATION; CONTROLLED STUDY; DNA DEGRADATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; KERATINOCYTE; NONHUMAN; PARAKERATOSIS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEOMICS; RAT; SIGNAL TRANSDUCTION; UPREGULATION; ANIMAL; ANTAGONISTS AND INHIBITORS; CYTOLOGY; GENETICS; METABOLISM; MOUSE; PHOSPHORYLATION; RNA INTERFERENCE;

ANIMALS; BONE MORPHOGENETIC PROTEIN 2; CELL DIFFERENTIATION; INTERMEDIATE FILAMENT PROTEINS; KERATIN-1; KERATIN-10; KERATINOCYTES; LAMIN TYPE A; MEMBRANE PROTEINS; MICE; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RNA INTERFERENCE; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; SMAD1 PROTEIN;

EID: 84947039672     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/cdd.2015.62     Document Type: Article

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