Blockade of nociceptin/orphanin FQ receptor signaling reverses LPS-induced depressive-like behavior in mice

Peptides

Volumn 72, Issue , 2015, Pages 95-103

  Medeiros, Iris U ^a,b   Ruzza, Chiara ^b   Asth, Laila ^a   Guerrini, Remo ^b   Romão, Pedro R T ^c   Gavioli, Elaine C ^a   Calo, Girolamo ^b  

^a FEDERAL UNIVERSITY OF RIO GRANDE DO NORTE   (Brazil)

^b UNIVERSITY OF FERRARA   (Italy)

^c UNIVERSIDADE FEDERAL DE CIÊNCIAS DA SAÚDE DE PORTO ALEGRE   (Brazil)

Author keywords

Depression; Inflammation; Lipopolysaccharide induced depressive; Nociceptin orphanin FQ; NOP receptor; Tail suspension test

Indexed keywords

INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; NOCICEPTIN RECEPTOR; NOCICEPTIN RECEPTOR ANTAGONIST; NORTRIPTYLINE; SB 612111; TUMOR NECROSIS FACTOR ALPHA; UFP 101; UNCLASSIFIED DRUG; ANTIDEPRESSANT AGENT; OPIATE RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DEPRESSION; FLUID INTAKE; FOOD INTAKE; MALE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RECEPTOR BLOCKING; RECTUM TEMPERATURE; TAIL SUSPENSION TEST; WEIGHT REDUCTION; ANIMAL; BLOOD; CHEMICALLY INDUCED; DRUG EFFECTS; GENETICS; KNOCKOUT MOUSE; METABOLISM; SIGNAL TRANSDUCTION;

ANIMALS; ANTIDEPRESSIVE AGENTS; DEPRESSION; INTERLEUKIN-6; LIPOPOLYSACCHARIDES; MICE; MICE, KNOCKOUT; RECEPTORS, OPIOID; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84947028255     PISSN: 01969781     EISSN: 18735169     Source Type: Journal    
DOI: 10.1016/j.peptides.2015.05.006     Document Type: Article

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