HLA supertype variation across populations: new insights into the role of natural selection in the evolution of HLA-A and HLA-B polymorphisms

Immunogenetics

Volumn 67, Issue 11-12, 2015, Pages 651-663

  dos Santos Francisco, Rodrigo ^a,b,c   Buhler, Stéphane ^b,d   Nunes, José Manuel ^b,e   Bitarello, Bárbara Domingues ^a   França, Gustavo Starvaggi ^a,f   Meyer, Diogo ^a   Sanchez Mazas, Alicia ^b,e  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b UNIVERSITY OF GENEVA   (Switzerland)

^c HOSPITAL ISRAELITA ALBERT EINSTEIN   (Brazil)

^d GENEVA UNIVERSITY HOSPITALS   (Switzerland)

^e Institute of Genetics and Genomics in Geneva (iGE3)   (Switzerland)

^f HOSPITAL SÍRIO LIBANÊS   (Brazil)

Author keywords

Adaptation; HLA; Human populations; Natural selection; Pathogens; Supertypes

Indexed keywords

HLA A ANTIGEN; HLA B ANTIGEN; EPITOPE;

AFRICAN; AMERICAN INDIAN; ARTICLE; AUSTRALIAN; BALANCING SELECTION; CORRELATION ANALYSIS; GENE FREQUENCY; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GEOGRAPHIC DISTRIBUTION; HETEROZYGOSITY; HUMAN; NATURAL SELECTION; POPULATION DIFFERENTIATION; PRIORITY JOURNAL; TAIWANESE; CLASSIFICATION; COMPUTER SIMULATION; EVOLUTION; FACTUAL DATABASE; GENETIC SELECTION; GENETICS; HISTOCOMPATIBILITY TEST; IMMUNOLOGY; INTERNATIONAL COOPERATION; POPULATION GENETICS;

BIOLOGICAL EVOLUTION; COMPUTER SIMULATION; DATABASES, FACTUAL; GENETICS, POPULATION; HISTOCOMPATIBILITY TESTING; HLA-A ANTIGENS; HLA-B ANTIGENS; HUMANS; IMMUNODOMINANT EPITOPES; INTERNATIONAL AGENCIES; POLYMORPHISM, GENETIC; SELECTION, GENETIC;

EID: 84947027842     PISSN: 00937711     EISSN: 14321211     Source Type: Journal    
DOI: 10.1007/s00251-015-0875-9     Document Type: Article

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