-
1
-
-
20444406500
-
Local radiation therapy of B16 melanoma tumors increases the generation of tumor antigen-specific effector cells that traffic to the tumor
-
PMID:15944250
-
Lugade AA, Moran JP, Gerber SA, Rose RC, Frelinger JG, Lord EM. Local radiation therapy of B16 melanoma tumors increases the generation of tumor antigen-specific effector cells that traffic to the tumor. J Immunol 2005; 174:7516-23; PMID:15944250; http://dx.doi.org/10.4049/jimmunol.174.12.7516
-
(2005)
J Immunol
, vol.174
, pp. 7516-7523
-
-
Lugade, A.A.1
Moran, J.P.2
Gerber, S.A.3
Rose, R.C.4
Frelinger, J.G.5
Lord, E.M.6
-
2
-
-
84890124077
-
Therapeutic immunization and local low-dose tumor irradiation, a reinforcing combination
-
PMID:23922012
-
Draghiciu O, Walczak M, Hoogeboom BN, Franken KL, Melief KJ, Nijman HW, Daemen T. Therapeutic immunization and local low-dose tumor irradiation, a reinforcing combination. Int J Cancer 2014; 134 (4):859-72; PMID:23922012; http://dx.doi.org/10.1002/ijc.28418
-
(2014)
Int J Cancer
, vol.134
, Issue.4
, pp. 859-872
-
-
Draghiciu, O.1
Walczak, M.2
Hoogeboom, B.N.3
Franken, K.L.4
Melief, K.J.5
Nijman, H.W.6
Daemen, T.7
-
3
-
-
4644342928
-
Concomitant tumor immunity to a poorly immunogenic melanoma is prevented by regulatory T cells
-
PMID:15381730
-
Turk MJ, Guevara-Patino JA, Rizzuto GA, Engelhorn ME, Sakaguchi S, Houghton AN. Concomitant tumor immunity to a poorly immunogenic melanoma is prevented by regulatory T cells. J Exp Med 2004; 200:771-82; PMID:15381730; http://dx.doi.org/10.1084/jem.20041130
-
(2004)
J Exp Med
, vol.200
, pp. 771-782
-
-
Turk, M.J.1
Guevara-Patino, J.A.2
Rizzuto, G.A.3
Engelhorn, M.E.4
Sakaguchi, S.5
Houghton, A.N.6
-
4
-
-
84858785703
-
Coordinated regulation of myeloid cells by tumours
-
PMID:22437938
-
Gabrilovich DI, Ostrand-Rosenberg S, Bronte V. Coordinated regulation of myeloid cells by tumours. Nat Rev Immunol 2012; 12:253-68; PMID:22437938; http://dx.doi.org/10.1038/nri3175
-
(2012)
Nat Rev Immunol
, vol.12
, pp. 253-268
-
-
Gabrilovich, D.I.1
Ostrand-Rosenberg, S.2
Bronte, V.3
-
5
-
-
84857219446
-
Monocytic CCR2 (C) myeloid-derived suppressor cells promote immune escape by limiting activated CD8 T-cell infiltration into the tumor microenvironment
-
PMID:22174368
-
Lesokhin AM, Hohl TM, Kitano S, Cortez C, Hirschhorn- Cymerman D, Avogadri F, Rizzuto GA, Lazarus JJ, Pamer EG, Houghton AN, et al. Monocytic CCR2 (C) myeloid-derived suppressor cells promote immune escape by limiting activated CD8 T-cell infiltration into the tumor microenvironment. Cancer Res 2012; 72:876-86; PMID:22174368; http://dx.doi.org/10.1158/0008-5472.CAN-11-1792
-
(2012)
Cancer Res
, vol.72
, pp. 876-886
-
-
Lesokhin, A.M.1
Hohl, T.M.2
Kitano, S.3
Cortez, C.4
Hirschhorn- Cymerman, D.5
Avogadri, F.6
Rizzuto, G.A.7
Lazarus, J.J.8
Pamer, E.G.9
Houghton, A.N.10
-
6
-
-
84875462761
-
Myeloid-derived suppressor cells suppress antitumor immune responses through IDO expression and correlate with lymph node metastasis in patients with breast cancer
-
PMID:23440412
-
Yu J, Du W, Yan F, Wang Y, Li H, Cao S, Yu W, Shen C, Liu J, Ren X. Myeloid-derived suppressor cells suppress antitumor immune responses through IDO expression and correlate with lymph node metastasis in patients with breast cancer. J Immunol 2013; 190:3783-97; PMID:23440412; http://dx.doi.org/10.4049/jimmunol.1201449
-
(2013)
J Immunol
, vol.190
, pp. 3783-3797
-
-
Yu, J.1
Du, W.2
Yan, F.3
Wang, Y.4
Li, H.5
Cao, S.6
Yu, W.7
Shen, C.8
Liu, J.9
Ren, X.10
-
7
-
-
34248172324
-
Altered macrophage differentiation and immune dysfunction in tumor development
-
PMID:17476345
-
Sica A, Bronte V. Altered macrophage differentiation and immune dysfunction in tumor development. J Clin Invest 2007; 117:1155-66; PMID:17476345; http://dx.doi.org/10.1172/JCI31422
-
(2007)
J Clin Invest
, vol.117
, pp. 1155-1166
-
-
Sica, A.1
Bronte, V.2
-
8
-
-
61349100687
-
Myeloid-derived suppressor cells as regulators of the immune system
-
PMID:19197294
-
Gabrilovich DI, Nagaraj S. Myeloid-derived suppressor cells as regulators of the immune system. Nat Rev Immunol 2009; 9:162-74; PMID:19197294; http://dx.doi.org/10.1038/nri2506
-
(2009)
Nat Rev Immunol
, vol.9
, pp. 162-174
-
-
Gabrilovich, D.I.1
Nagaraj, S.2
-
9
-
-
84877825407
-
Therapeutic regulation of myeloid-derived suppressor cells and immune response to cancer vaccine in patients with extensive stage small cell lung cancer
-
PMID:23589106
-
Iclozan C, Antonia S, Chiappori A, Chen DT, Gabrilovich D. Therapeutic regulation of myeloid-derived suppressor cells and immune response to cancer vaccine in patients with extensive stage small cell lung cancer. Cancer Immunol Immunother 2013; 62:909-18; PMID:23589106; http://dx.doi.org/10.1007/s00262-013-1396-8
-
(2013)
Cancer Immunol Immunother
, vol.62
, pp. 909-918
-
-
Iclozan, C.1
Antonia, S.2
Chiappori, A.3
Chen, D.T.4
Gabrilovich, D.5
-
10
-
-
84863991235
-
Myeloid suppressor cell depletion augments antitumor activity in lung cancer
-
PMID:22815789
-
Srivastava MK, Zhu L, Harris-White M, Kar UK, Huang M, Johnson MF, Lee JM, Elashoff D, Strieter R, Dubinett S, et al. Myeloid suppressor cell depletion augments antitumor activity in lung cancer. PLOS ONE 2012; 7:e40677; PMID:22815789; http://dx.doi.org/10.1371/journal.pone.0040677
-
(2012)
PLOS ONE
, vol.7
-
-
Srivastava, M.K.1
Zhu, L.2
Harris-White, M.3
Kar, U.K.4
Huang, M.5
Johnson, M.F.6
Lee, J.M.7
Elashoff, D.8
Strieter, R.9
Dubinett, S.10
-
11
-
-
84883445852
-
Long-term response to sunitinib therapy for metastatic renal cell carcinoma
-
PMID:23707221
-
Molina AM, Jia X, Feldman DR, Hsieh JJ, Ginsberg MS, Velasco S, Patil S, Motzer RJ. Long-term response to sunitinib therapy for metastatic renal cell carcinoma. Clin Genitourin Cancer 2013; 11:297-302; PMID:23707221; http://dx.doi.org/10.1016/j.clgc.2013.04.001
-
(2013)
Clin Genitourin Cancer
, vol.11
, pp. 297-302
-
-
Molina, A.M.1
Jia, X.2
Feldman, D.R.3
Hsieh, J.J.4
Ginsberg, M.S.5
Velasco, S.6
Patil, S.7
Motzer, R.J.8
-
12
-
-
33846181370
-
Sunitinib versus interferon alfa in metastatic renal-cell carcinoma
-
PMID:17215529
-
Motzer RJ, Hutson TE, Tomczak P, Michaelson MD, Bukowski RM, Rixe O, Oudard S, Negrier S, Szczylik C, Kim ST, et al. Sunitinib versus interferon alfa in metastatic renal-cell carcinoma. N Engl J Med 2007; 356:115-24; PMID:17215529; http://dx.doi.org/10.1056/NEJMoa065044
-
(2007)
N Engl J Med
, vol.356
, pp. 115-124
-
-
Motzer, R.J.1
Hutson, T.E.2
Tomczak, P.3
Michaelson, M.D.4
Bukowski, R.M.5
Rixe, O.6
Oudard, S.7
Negrier, S.8
Szczylik, C.9
Kim, S.T.10
-
13
-
-
77954269924
-
Molecular basis and management of gastrointestinal stromal tumors
-
PMID:20533592
-
Bayraktar UD, Bayraktar S, Rocha-Lima CM. Molecular basis and management of gastrointestinal stromal tumors. World J Gastroenterol 2010; 16:2726-34; PMID:20533592; http://dx.doi.org/10.3748/wjg.v16.i22.2726
-
(2010)
World J Gastroenterol
, vol.16
, pp. 2726-2734
-
-
Bayraktar, U.D.1
Bayraktar, S.2
Rocha-Lima, C.M.3
-
14
-
-
33745098620
-
Contribution of individual targets to the antitumor efficacy of the multitargeted receptor tyrosine kinase inhibitor SU11248
-
PMID:16731761
-
Potapova O, Laird AD, Nannini MA, Barone A, Li G, Moss KG, Cherrington JM, Mendel DB. Contribution of individual targets to the antitumor efficacy of the multitargeted receptor tyrosine kinase inhibitor SU11248. Mol Cancer Ther 2006; 5:1280-9; PMID:16731761; http://dx.doi.org/10.1158/1535-7163.MCT-03-0156
-
(2006)
Mol Cancer Ther
, vol.5
, pp. 1280-1289
-
-
Potapova, O.1
Laird, A.D.2
Nannini, M.A.3
Barone, A.4
Li, G.5
Moss, K.G.6
Cherrington, J.M.7
Mendel, D.B.8
-
15
-
-
77956920766
-
Characterization of cytokine-induced myeloid-derived suppressor cells from normal human peripheral blood mononuclear cells
-
PMID:20644162
-
Lechner MG, Liebertz DJ, Epstein AL. Characterization of cytokine-induced myeloid-derived suppressor cells from normal human peripheral blood mononuclear cells. J Immunol 2010; 185:2273-84; PMID:20644162; http://dx.doi.org/10.4049/jimmunol.1000901 [doi]
-
(2010)
J Immunol
, vol.185
, pp. 2273-2284
-
-
Lechner, M.G.1
Liebertz, D.J.2
Epstein, A.L.3
-
16
-
-
38049181485
-
Reversion of immune tolerance in advanced malignancy: Modulation of myeloid-derived suppressor cell development by blockade of stem-cell factor function
-
PMID:17885078
-
Pan PY, Wang GX, Yin B, Ozao J, Ku T, Divino CM, Chen SH. Reversion of immune tolerance in advanced malignancy: Modulation of myeloid-derived suppressor cell development by blockade of stem-cell factor function. Blood 2008; 111:219-28; PMID:17885078; http://dx.doi.org/10.1182/blood-2007-04-086835 [pii].
-
(2008)
Blood
, vol.111
, pp. 219-228
-
-
Pan, P.Y.1
Wang, G.X.2
Yin, B.3
Ozao, J.4
Ku, T.5
Divino, C.M.6
Chen, S.H.7
-
17
-
-
10744232280
-
C-kit-targeting immunotherapy for hereditary melanoma in a mouse model
-
PMID:14871802
-
Kato M, Takeda K, Kawamoto Y, Tsuzuki T, Hossain K, Tamakoshi A, Kunisada T, Kambayashi Y, Ogino K, Suzuki H, et al. C-kit-targeting immunotherapy for hereditary melanoma in a mouse model. Cancer Res 2004; 64:801-6; PMID:14871802; http://dx.doi.org/10.1158/0008-5472.CAN-03-2532
-
(2004)
Cancer Res
, vol.64
, pp. 801-806
-
-
Kato, M.1
Takeda, K.2
Kawamoto, Y.3
Tsuzuki, T.4
Hossain, K.5
Tamakoshi, A.6
Kunisada, T.7
Kambayashi, Y.8
Ogino, K.9
Suzuki, H.10
-
18
-
-
84901008789
-
Control of the immune response by pro-angiogenic factors
-
PMID:24765614
-
Voron T, Marcheteau E, Pernot S, Colussi O, Tartour E, Taieb J, Terme M. Control of the immune response by pro-angiogenic factors. Front Oncol 2014; 4:70; PMID:24765614; http://dx.doi.org/10.3389/fonc.2014.00070
-
(2014)
Front Oncol
, vol.4
, pp. 70
-
-
Voron, T.1
Marcheteau, E.2
Pernot, S.3
Colussi, O.4
Tartour, E.5
Taieb, J.6
Terme, M.7
-
19
-
-
48549085973
-
Myeloidderived suppressor cells promote cross-tolerance in Bcell lymphoma by expanding regulatory T cells
-
PMID:18593947
-
Serafini P, Mgebroff S, Noonan K, Borrello I. Myeloidderived suppressor cells promote cross-tolerance in Bcell lymphoma by expanding regulatory T cells. Cancer Res 2008; 68:5439-49; PMID:18593947; http://dx.doi.org/10.1158/0008-5472.CAN-07-6621
-
(2008)
Cancer Res
, vol.68
, pp. 5439-5449
-
-
Serafini, P.1
Mgebroff, S.2
Noonan, K.3
Borrello, I.4
-
20
-
-
34047160027
-
CD69 expression as an index of T-cell function: Assay standardization, validation and use in monitoring immune recovery
-
PMID:17453964
-
Lindsey WB, Lowdell MW, Marti GE, Abbasi F, Zenger V, King KM, Lamb LS, Jr. CD69 expression as an index of T-cell function: Assay standardization, validation and use in monitoring immune recovery. Cytotherapy 2007; 9:123-32; PMID:17453964; http://dx.doi.org/10.1080/14653240601182838
-
(2007)
Cytotherapy
, vol.9
, pp. 123-132
-
-
Lindsey, W.B.1
Lowdell, M.W.2
Marti, G.E.3
Abbasi, F.4
Zenger, V.5
King, K.M.6
Lamb, L.S.7
-
21
-
-
84858785703
-
Coordinated regulation of myeloid cells by tumours
-
PMID:22437938
-
Gabrilovich DI, Ostrand-Rosenberg S, Bronte V. Coordinated regulation of myeloid cells by tumours. Nat Rev Immunol 2012; 12:253-68; PMID:22437938; http://dx.doi.org/10.1038/nri3175
-
(2012)
Nat Rev Immunol
, vol.12
, pp. 253-268
-
-
Gabrilovich, D.I.1
Ostrand-Rosenberg, S.2
Bronte, V.3
-
22
-
-
7244240998
-
Superior therapeutic efficacy of alphavirus-mediated immunization against human papilloma virus type 16 antigens in a murine tumour model
-
PMID:15535411
-
Daemen T, Riezebos-Brilman A, Regts J, Dontje B, van der Zee A, Wilschut J. Superior therapeutic efficacy of alphavirus-mediated immunization against human papilloma virus type 16 antigens in a murine tumour model: Effects of the route of immunization. Antivir Ther 2004; 9:733-42; PMID:15535411
-
(2004)
Effects of the Route of Immunization. Antivir Ther
, vol.9
, pp. 733-742
-
-
Daemen, T.1
Riezebos-Brilman, A.2
Regts, J.3
Dontje, B.4
Van Der Zee, A.5
Wilschut, J.6
-
23
-
-
65549129226
-
Sunitinib inhibition of Stat3 induces renal cell carcinoma tumor cell apoptosis and reduces immunosuppressive cells
-
PMID:19244102
-
Xin H, Zhang C, Herrmann A, Du Y, Figlin R, Yu H. Sunitinib inhibition of Stat3 induces renal cell carcinoma tumor cell apoptosis and reduces immunosuppressive cells. Cancer Res 2009; 69:2506-13; PMID:19244102; http://dx.doi.org/10.1158/0008-5472.CAN-08-4323
-
(2009)
Cancer Res
, vol.69
, pp. 2506-2513
-
-
Xin, H.1
Zhang, C.2
Herrmann, A.3
Du, Y.4
Figlin, R.5
Yu, H.6
-
24
-
-
84866026922
-
Blockade of NFkappaB activity by sunitinib increases cell death in bortezomib-treated endometrial carcinoma cells
-
PMID:22819259
-
Sorolla A, Yeramian A, Valls J, Dolcet X, Bergada L, Llombart-Cussac A, Marti RM, Matias-Guiu X. Blockade of NFkappaB activity by sunitinib increases cell death in bortezomib-treated endometrial carcinoma cells. Mol Oncol 2012; 6:530-41; PMID:22819259; http://dx.doi.org/10.1016/j.molonc.2012.06.006 [doi].
-
(2012)
Mol Oncol
, vol.6
, pp. 530-541
-
-
Sorolla, A.1
Yeramian, A.2
Valls, J.3
Dolcet, X.4
Bergada, L.5
Llombart-Cussac, A.6
Marti, R.M.7
Matias-Guiu, X.8
-
25
-
-
84875783182
-
In vitro and in vivo analysis of RTK inhibitor efficacy and identification of its novel targets in glioblastomas
-
PMID:23544171
-
Martinho O, Silva-Oliveira R, Miranda-Goncalves V, Clara C, Almeida JR, Carvalho AL, Barata JT, Reis RM. In vitro and in vivo analysis of RTK inhibitor efficacy and identification of its novel targets in glioblastomas. Transl Oncol 2013; 6:187-96; PMID:23544171; http://dx.doi.org/10.1593/tlo.12400
-
(2013)
Transl Oncol
, vol.6
, pp. 187-196
-
-
Martinho, O.1
Silva-Oliveira, R.2
Miranda-Goncalves, V.3
Clara, C.4
Almeida, J.R.5
Carvalho, A.L.6
Barata, J.T.7
Reis, R.M.8
-
26
-
-
0035201127
-
Tumorinduced immune dysfunctions caused by myeloid suppressor cells
-
PMID:11759067
-
Bronte V, Serafini P, Apolloni E, Zanovello P. Tumorinduced immune dysfunctions caused by myeloid suppressor cells. J Immunother 2001; 24:431-46; PMID:11759067; http://dx.doi.org/10.11207/jimmunother.1524-9557
-
(2001)
J Immunother
, vol.24
, pp. 431-446
-
-
Bronte, V.1
Serafini, P.2
Apolloni, E.3
Zanovello, P.4
-
27
-
-
0035164478
-
Increased production of immature myeloid cells in cancer patients: A mechanism of immunosuppression in cancer
-
PMID:11123353
-
Almand B, Clark JI, Nikitina E, van Beynen J, English NR, Knight SC, Carbone DP, Gabrilovich DI. Increased production of immature myeloid cells in cancer patients: A mechanism of immunosuppression in cancer. J Immunol 2001; 166:678-89; PMID:11123353; http://dx.doi.org/10.4049/jimmunol.166.1.678
-
(2001)
J Immunol
, vol.166
, pp. 678-689
-
-
Almand, B.1
Clark, J.I.2
Nikitina, E.3
Van Beynen, J.4
English, N.R.5
Knight, S.C.6
Carbone, D.P.7
Gabrilovich, D.I.8
-
28
-
-
84857789296
-
The secret ally: Immunostimulation by anticancer drugs
-
PMID:22301798
-
Galluzzi L, Senovilla L, Zitvogel L, Kroemer G. The secret ally: Immunostimulation by anticancer drugs. Nat Rev Drug Discov 2012; 11:215-33; PMID:22301798; http://dx.doi.org/10.1038/nrd3626
-
(2012)
Nat Rev Drug Discov
, vol.11
, pp. 215-233
-
-
Galluzzi, L.1
Senovilla, L.2
Zitvogel, L.3
Kroemer, G.4
-
29
-
-
65549141834
-
The novel role of tyrosine kinase inhibitor in the reversal of immune suppression and modulation of tumor microenvironment for immune-based cancer therapies
-
PMID:19276342
-
Ozao-Choy J, Ma G, Kao J, Wang GX, Meseck M, Sung M, Schwartz M, Divino CM, Pan PY, Chen SH. The novel role of tyrosine kinase inhibitor in the reversal of immune suppression and modulation of tumor microenvironment for immune-based cancer therapies. Cancer Res 2009; 69:2514-22; PMID:19276342; http://dx.doi.org/10.1158/0008-5472.CAN-08-4709
-
(2009)
Cancer Res
, vol.69
, pp. 2514-2522
-
-
Ozao-Choy, J.1
Ma, G.2
Kao, J.3
Wang, G.X.4
Meseck, M.5
Sung, M.6
Schwartz, M.7
Divino, C.M.8
Pan, P.Y.9
Chen, S.H.10
-
30
-
-
25144466458
-
Gemcitabine selectively eliminates splenic gr-1C/CD11bC myeloid suppressor cells in tumor-bearing animals and enhances antitumor immune activity
-
PMID:16166452
-
Suzuki E, Kapoor V, Jassar AS, Kaiser LR, Albelda SM. Gemcitabine selectively eliminates splenic gr-1C/CD11bC myeloid suppressor cells in tumor-bearing animals and enhances antitumor immune activity. Clin Cancer Res 2005; 11:6713-21; PMID:16166452; http://dx.doi.org/10.1158/1078-0432.CCR-05-0883
-
(2005)
Clin Cancer Res
, vol.11
, pp. 6713-6721
-
-
Suzuki, E.1
Kapoor, V.2
Jassar, A.S.3
Kaiser, L.R.4
Albelda, S.M.5
-
31
-
-
33744954585
-
Sunitinib in patients with metastatic renal cell carcinoma
-
PMID:16757724
-
Motzer RJ, Rini BI, Bukowski RM, Curti BD, George DJ, Hudes GR, Redman BG, Margolin KA, Merchan JR, Wilding G, et al. Sunitinib in patients with metastatic renal cell carcinoma. JAMA 2006; 295:2516-24; PMID:16757724; http://dx.doi.org/10.1001/jama.295.21.2516
-
(2006)
JAMA
, vol.295
, pp. 2516-2524
-
-
Motzer, R.J.1
Rini, B.I.2
Bukowski, R.M.3
Curti, B.D.4
George, D.J.5
Hudes, G.R.6
Redman, B.G.7
Margolin, K.A.8
Merchan, J.R.9
Wilding, G.10
-
32
-
-
33644847440
-
Safety, pharmacokinetic, and antitumor activity of SU11248, a novel oral multitarget tyrosine kinase inhibitor, in patients with cancer
-
PMID:16314617
-
Faivre S, Delbaldo C, Vera K, Robert C, Lozahic S, Lassau N, Bello C, Deprimo S, Brega N, Massimini G, et al. Safety, pharmacokinetic, and antitumor activity of SU11248, a novel oral multitarget tyrosine kinase inhibitor, in patients with cancer. J Clin Oncol 2006; 24:25-35; PMID:16314617; http://dx.doi.org/10.1200/JCO.2005.02.2194
-
(2006)
J Clin Oncol
, vol.24
, pp. 25-35
-
-
Faivre, S.1
Delbaldo, C.2
Vera, K.3
Robert, C.4
Lozahic, S.5
Lassau, N.6
Bello, C.7
Deprimo, S.8
Brega, N.9
Massimini, G.10
-
33
-
-
12244301581
-
In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: Determination of a pharmacokinetic/pharmacodynamic relationship
-
PMID:12538485
-
Mendel DB, Laird AD, Xin X, Louie SG, Christensen JG, Li G, Schreck RE, Abrams TJ, Ngai TJ, Lee LB, et al. In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: Determination of a pharmacokinetic/pharmacodynamic relationship. Clin Cancer Res 2003; 9:327-37; PMID:12538485; http://dx.doi.org/10.1158/1078-0432.CCR-02-2832
-
(2003)
Clin Cancer Res
, vol.9
, pp. 327-337
-
-
Mendel, D.B.1
Laird, A.D.2
Xin, X.3
Louie, S.G.4
Christensen, J.G.5
Li, G.6
Schreck, R.E.7
Abrams, T.J.8
Ngai, T.J.9
Lee, L.B.10
-
34
-
-
84883155077
-
Systemic treatment options for untreated patients with metastatic clear cell renal cancer
-
PMID:23972707
-
Molina AM, Motzer RJ, Heng DY. Systemic treatment options for untreated patients with metastatic clear cell renal cancer. Semin Oncol 2013; 40:436-43; PMID:23972707; http://dx.doi.org/10.1053/j.seminoncol.2013.05.013
-
(2013)
Semin Oncol
, vol.40
, pp. 436-443
-
-
Molina, A.M.1
Motzer, R.J.2
Heng, D.Y.3
-
35
-
-
79953221190
-
Kinase inhibitor sorafenib modulates immunosuppressive cell populations in a murine liver cancer model
-
PMID:21321535
-
Cao M, Xu Y, Youn JI, Cabrera R, Zhang X, Gabrilovich D, Nelson DR, Liu C. Kinase inhibitor sorafenib modulates immunosuppressive cell populations in a murine liver cancer model. Lab Invest 2011; 91:598-608; PMID:21321535; http://dx.doi.org/10.1038/labinvest.2010.205
-
(2011)
Lab Invest
, vol.91
, pp. 598-608
-
-
Cao, M.1
Xu, Y.2
Youn, J.I.3
Cabrera, R.4
Zhang, X.5
Gabrilovich, D.6
Nelson, D.R.7
Liu, C.8
-
36
-
-
63549105681
-
Sunitinib mediates reversal of myeloid-derived suppressor cell accumulation in renal cell carcinoma patients
-
PMID:19276286
-
Ko JS, Zea AH, Rini BI, Ireland JL, Elson P, Cohen P, Golshayan A, Rayman PA, Wood L, Garcia J, et al. Sunitinib mediates reversal of myeloid-derived suppressor cell accumulation in renal cell carcinoma patients. Clin Cancer Res 2009; 15:2148-57; PMID:19276286; http://dx.doi.org/10.1158/1078-0432.CCR-08-1332
-
(2009)
Clin Cancer Res
, vol.15
, pp. 2148-2157
-
-
Ko, J.S.1
Zea, A.H.2
Rini, B.I.3
Ireland, J.L.4
Elson, P.5
Cohen, P.6
Golshayan, A.7
Rayman, P.A.8
Wood, L.9
Garcia, J.10
-
37
-
-
77951754469
-
Direct and differential suppression of myeloid-derived suppressor cell subsets by sunitinib is compartmentally constrained
-
PMID:20406969
-
Ko JS, Rayman P, Ireland J, Swaidani S, Li G, Bunting KD, Rini B, Finke JH, Cohen PA. Direct and differential suppression of myeloid-derived suppressor cell subsets by sunitinib is compartmentally constrained. Cancer Res 2010; 70:3526-36; PMID:20406969; http://dx.doi.org/10.1158/0008-5472.CAN-09-3278
-
(2010)
Cancer Res
, vol.70
, pp. 3526-3536
-
-
Ko, J.S.1
Rayman, P.2
Ireland, J.3
Swaidani, S.4
Li, G.5
Bunting, K.D.6
Rini, B.7
Finke, J.H.8
Cohen, P.A.9
-
38
-
-
84866874594
-
Immunological effects of multikinase inhibitors for kidney cancer: A clue for integration with cellular therapies?
-
PMID:21716852
-
Porta C, Paglino C, Imarisio I, Ganini C, Pedrazzoli P. Immunological effects of multikinase inhibitors for kidney cancer: A clue for integration with cellular therapies? J Cancer 2011; 2:333-8; PMID:21716852; http://dx.doi.org/10.1074/jc.v2.3119398
-
(2011)
J Cancer
, vol.2
, pp. 333-338
-
-
Porta, C.1
Paglino, C.2
Imarisio, I.3
Ganini, C.4
Pedrazzoli, P.5
-
39
-
-
38449097166
-
Antiangiogenic and anti-invasive effects of sunitinib on experimental human glioblastoma
-
PMID:17622648
-
de Bouard S, Herlin P, Christensen JG, Lemoisson E, Gauduchon P, Raymond E, Guillamo JS. Antiangiogenic and anti-invasive effects of sunitinib on experimental human glioblastoma. Neuro Oncol 2007; 9:412-23; PMID:17622648; http://dx.doi.org/10.1215/15228517-2007-024
-
(2007)
Neuro Oncol
, vol.9
, pp. 412-423
-
-
De Bouard, S.1
Herlin, P.2
Christensen, J.G.3
Lemoisson, E.4
Gauduchon, P.5
Raymond, E.6
Guillamo, J.S.7
-
40
-
-
84896313968
-
The effect of the anti-angiogenic drug sunitinib malate on the vascular architecture of oral squamous cell carcinoma
-
PMID:24458724
-
Bampi VF, Gomes CF, De Oliveira LB, Da Silva JL. The effect of the anti-angiogenic drug sunitinib malate on the vascular architecture of oral squamous cell carcinoma. Microsc Res Tech 2014; 77(4):250-6; PMID:24458724; http://dx.doi.org/10.1002/jemt.22336
-
(2014)
Microsc Res Tech
, vol.77
, Issue.4
, pp. 250-256
-
-
Bampi, V.F.1
Gomes, C.F.2
De Oliveira, L.B.3
Da Silva, J.L.4
-
41
-
-
75149130051
-
Targeting the cancer kinome through polypharmacology
-
PMID:20094047
-
Knight ZA, Lin H, Shokat KM. Targeting the cancer kinome through polypharmacology. Nat Rev Cancer 2010; 10:130-7; PMID:20094047; http://dx.doi.org/10.1038/nrc2787
-
(2010)
Nat Rev Cancer
, vol.10
, pp. 130-137
-
-
Knight, Z.A.1
Lin, H.2
Shokat, K.M.3
-
42
-
-
84892686102
-
Doxorubicin eliminates myeloid-derived suppressor cells and enhances the efficacy of adoptive T-cell transfer in breast cancer
-
PMID:24197130
-
Alizadeh D, Trad M, Hanke NT, Larmonier CB, Janikashvili N, Bonnotte B, Katsanis E, Larmonier N. Doxorubicin eliminates myeloid-derived suppressor cells and enhances the efficacy of adoptive T-cell transfer in breast cancer. Cancer Res 2014; 74:104-18; PMID:24197130; http://dx.doi.org/10.1158/0008-5472.CAN-13-1545
-
(2014)
Cancer Res
, vol.74
, pp. 104-118
-
-
Alizadeh, D.1
Trad, M.2
Hanke, N.T.3
Larmonier, C.B.4
Janikashvili, N.5
Bonnotte, B.6
Katsanis, E.7
Larmonier, N.8
-
43
-
-
47049127786
-
Sorafenib, but not sunitinib, affects function of dendritic cells and induction of primary immune responses
-
PMID:18310500
-
Hipp MM, Hilf N, Walter S, Werth D, Brauer KM, Radsak MP, Weinschenk T, Singh-Jasuja H, Brossart P. Sorafenib, but not sunitinib, affects function of dendritic cells and induction of primary immune responses. Blood 2008; 111:5610-20; PMID:18310500; http://dx.doi.org/10.1182/blood-2007-02-075945
-
(2008)
Blood
, vol.111
, pp. 5610-5620
-
-
Hipp, M.M.1
Hilf, N.2
Walter, S.3
Werth, D.4
Brauer, K.M.5
Radsak, M.P.6
Weinschenk, T.7
Singh-Jasuja, H.8
Brossart, P.9
-
44
-
-
79958052123
-
MDSC as a mechanism of tumor escape from sunitinib mediated anti-angiogenic therapy
-
PMID:21315783
-
Finke J, Ko J, Rini B, Rayman P, Ireland J, Cohen P. MDSC as a mechanism of tumor escape from sunitinib mediated anti-angiogenic therapy. Int Immunopharmacol 2011; 11:856-61; PMID:21315783; http://dx.doi.org/10.1016/j.intimp.2011.01.030
-
(2011)
Int Immunopharmacol
, vol.11
, pp. 856-861
-
-
Finke, J.1
Ko, J.2
Rini, B.3
Rayman, P.4
Ireland, J.5
Cohen, P.6
-
45
-
-
55849107422
-
Stat3 mediates myeloid cell-dependent tumor angiogenesis in mice
-
PMID:18776941
-
Kujawski M, Kortylewski M, Lee H, Herrmann A, Kay H, Yu H. Stat3 mediates myeloid cell-dependent tumor angiogenesis in mice. J Clin Invest 2008; 118:3367-77; PMID:18776941; http://dx.doi.org/10.1172/JCI35213
-
(2008)
J Clin Invest
, vol.118
, pp. 3367-3377
-
-
Kujawski, M.1
Kortylewski, M.2
Lee, H.3
Herrmann, A.4
Kay, H.5
Yu, H.6
-
46
-
-
79953177481
-
Role of regulatory T-cells in immunization strategies involving a recombinant alphavirus vector system
-
PMID:21447870
-
Walczak M, Regts J, van Oosterhout AJ, Boon L, Wilschut J, Nijman HW, Daemen T. Role of regulatory T-cells in immunization strategies involving a recombinant alphavirus vector system. Antivir Ther 2011; 16:207-18; PMID:21447870; http://dx.doi.org/10.3851/IMP1751
-
(2011)
Antivir Ther
, vol.16
, pp. 207-218
-
-
Walczak, M.1
Regts, J.2
Van Oosterhout, A.J.3
Boon, L.4
Wilschut, J.5
Nijman, H.W.6
Daemen, T.7
-
47
-
-
10744220561
-
Transforming growth factorbeta production and myeloid cells are an effector mechanism through which CD1d-restricted T cells block cytotoxic T lymphocyte-mediated tumor immunosurveillance: Abrogation prevents tumor recurrence
-
PMID:14657224
-
Terabe M, Matsui S, Park JM, Mamura M, Noben-Trauth N, Donaldson DD, Chen W, Wahl SM, Ledbetter S, Pratt B, et al. Transforming growth factorbeta production and myeloid cells are an effector mechanism through which CD1d-restricted T cells block cytotoxic T lymphocyte-mediated tumor immunosurveillance: Abrogation prevents tumor recurrence. J Exp Med 2003; 198:1741-52; PMID:14657224; http://dx.doi.org/10.1084/jem.20022227
-
(2003)
J Exp Med
, vol.198
, pp. 1741-1752
-
-
Terabe, M.1
Matsui, S.2
Park, J.M.3
Mamura, M.4
Noben-Trauth, N.5
Donaldson, D.D.6
Chen, W.7
Wahl, S.M.8
Ledbetter, S.9
Pratt, B.10
-
48
-
-
84857506147
-
Consequence of dose scheduling of sunitinib on host immune response elements and vaccine combination therapy
-
PMID:21633954
-
Farsaci B, Higgins JP, Hodge JW. Consequence of dose scheduling of sunitinib on host immune response elements and vaccine combination therapy. Int J Cancer 2012; 130:1948-59; PMID:21633954; http://dx.doi.org/10.1002/ijc.26219
-
(2012)
Int J Cancer
, vol.130
, pp. 1948-1959
-
-
Farsaci, B.1
Higgins, J.P.2
Hodge, J.W.3
-
49
-
-
36949001361
-
A comparative study on the immunotherapeutic efficacy of recombinant semliki forest virus and adenovirus vector systems in a murine model for cervical cancer
-
PMID:17928874
-
Riezebos-Brilman A, Walczak M, Regts J, Rots MG, Kamps G, Dontje B, Haisma HY, Wilschut J, Daemen T. A comparative study on the immunotherapeutic efficacy of recombinant semliki forest virus and adenovirus vector systems in a murine model for cervical cancer. Gene Ther 2007; 14:1695-704; PMID:17928874; http://dx.doi.org/10.1038/sj.gt.3303036
-
(2007)
Gene Ther
, vol.14
, pp. 1695-1704
-
-
Riezebos-Brilman, A.1
Walczak, M.2
Regts, J.3
Rots, M.G.4
Kamps, G.5
Dontje, B.6
Haisma, H.Y.7
Wilschut, J.8
Daemen, T.9
-
50
-
-
84892614614
-
Combination of sunitinib with anti-tumor vaccination inhibits T cell priming and requires careful scheduling to achieve productive immunotherapy
-
PMID:24105638
-
Jaini R, Rayman P, Cohen PA, Finke JH, Tuohy VK. Combination of sunitinib with anti-tumor vaccination inhibits T cell priming and requires careful scheduling to achieve productive immunotherapy. Int J Cancer 2014; 134:1695-705; PMID:24105638; http://dx.doi.org/10.1002/ijc.28488
-
(2014)
Int J Cancer
, vol.134
, pp. 1695-1705
-
-
Jaini, R.1
Rayman, P.2
Cohen, P.A.3
Finke, J.H.4
Tuohy, V.K.5
-
51
-
-
77952742185
-
Role of T cell competition in the induction of cytotoxic T lymphocyte activity during viral vector-based immunization regimens
-
PMID:20434555
-
Lambeck AJ, Nijman HW, Hoogeboom BN, Regts J, de Mare A, Wilschut J, Daemen T. Role of T cell competition in the induction of cytotoxic T lymphocyte activity during viral vector-based immunization regimens. Vaccine 2010; 28:4275-82; PMID:20434555; http://dx.doi.org/10.1016/j.vaccine.2010.04.033
-
(2010)
Vaccine
, vol.28
, pp. 4275-4282
-
-
Lambeck, A.J.1
Nijman, H.W.2
Hoogeboom, B.N.3
Regts, J.4
De Mare, A.5
Wilschut, J.6
Daemen, T.7
-
52
-
-
0030068375
-
Treatment of established tumors with a novel vaccine that enhances major histocompatibility class II presentation of tumor antigen
-
PMID:8548765
-
Lin KY, Guarnieri FG, Staveley-O’Carroll KF, Levitsky HI, August JT, Pardoll DM, Wu TC. Treatment of established tumors with a novel vaccine that enhances major histocompatibility class II presentation of tumor antigen. Cancer Res 1996; 56:21-6; PMID:8548765
-
(1996)
Cancer Res
, vol.56
, pp. 21-26
-
-
Lin, K.Y.1
Guarnieri, F.G.2
Staveley-O’carroll, K.F.3
Levitsky, H.I.4
August, J.T.5
Pardoll, D.M.6
Wu, T.C.7
-
53
-
-
73249125588
-
Gr-1 antibody induces STAT signaling, macrophage marker expression and abrogation of myeloid-derived suppressor cell activity in BM cells
-
PMID:19830733
-
Ribechini E, Leenen PJ, Lutz MB. Gr-1 antibody induces STAT signaling, macrophage marker expression and abrogation of myeloid-derived suppressor cell activity in BM cells. Eur J Immunol 2009; 39:3538-51; PMID:19830733; http://dx.doi.org/10.1002/eji.200939530
-
(2009)
Eur J Immunol
, vol.39
, pp. 3538-3551
-
-
Ribechini, E.1
Leenen, P.J.2
Lutz, M.B.3
-
54
-
-
0035710746
-
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-delta delta C(T)) method
-
PMID:11846609
-
Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-delta delta C(T)) method. Methods 2001; 25:402-8; PMID:11846609; http://dx.doi.org/10.1006/meth.2001.1262
-
(2001)
Methods
, vol.25
, pp. 402-408
-
-
Livak, K.J.1
Schmittgen, T.D.2
-
55
-
-
84856527732
-
S100A7 enhances mammary tumorigenesis through upregulation of inflammatory pathways
-
PMID:22158945
-
Nasser MW, Qamri Z, Deol YS, Ravi J, Powell CA, Trikha P, Schwendener RA, Bai XF, Shilo K, Zou X, et al. S100A7 enhances mammary tumorigenesis through upregulation of inflammatory pathways. Cancer Res 2012; 72:604-15; PMID:22158945; http://dx.doi.org/10.1158/0008-5472.CAN-11-0669
-
(2012)
Cancer Res
, vol.72
, pp. 604-615
-
-
Nasser, M.W.1
Qamri, Z.2
Deol, Y.S.3
Ravi, J.4
Powell, C.A.5
Trikha, P.6
Schwendener, R.A.7
Bai, X.F.8
Shilo, K.9
Zou, X.10
-
56
-
-
14044250862
-
IL-10 gene-deficient mice lack TGF-beta/smad signaling and fail to inhibit proinflammatory gene expression in intestinal epithelial cells after the colonization with colitogenic enterococcus faecalis
-
PMID:15728512
-
Ruiz PA, Shkoda A, Kim SC, Sartor RB, Haller D. IL-10 gene-deficient mice lack TGF-beta/smad signaling and fail to inhibit proinflammatory gene expression in intestinal epithelial cells after the colonization with colitogenic enterococcus faecalis. J Immunol 2005; 174:2990-9; PMID:15728512; http://dx.doi.org/10.4049/jimmunol.174.5.2990
-
(2005)
J Immunol
, vol.174
, pp. 2990-2999
-
-
Ruiz, P.A.1
Shkoda, A.2
Kim, S.C.3
Sartor, R.B.4
Haller, D.5
-
57
-
-
6344240464
-
Blocking programmed death-1 ligand-PD-1 interactions by local gene therapy results in enhancement of antitumor effect of secondary lymphoid tissue chemokine
-
PMID:15470033
-
He YF, Zhang GM, Wang XH, Zhang H, Yuan Y, Li D, Feng ZH. Blocking programmed death-1 ligand-PD-1 interactions by local gene therapy results in enhancement of antitumor effect of secondary lymphoid tissue chemokine. J Immunol 2004; 173:4919-28; PMID:15470033; http://dx.doi.org/10.4049/jimmunol.173.8.4919
-
(2004)
J Immunol
, vol.173
, pp. 4919-4928
-
-
He, Y.F.1
Zhang, G.M.2
Wang, X.H.3
Zhang, H.4
Yuan, Y.5
Li, D.6
Feng, Z.H.7
-
58
-
-
33750599405
-
CD4CPD-1C T cells acting as regulatory cells during the induction of anterior chamber-associated immune deviation
-
PMID:17003438
-
Meng Q, Yang P, Li B, Zhou H, Huang X, Zhu L, Ren Y, Kijlstra A. CD4CPD-1C T cells acting as regulatory cells during the induction of anterior chamber-associated immune deviation. Invest Ophthalmol Vis Sci 2006; 47:4444-52; PMID:17003438; http://dx.doi.org/10.1167/iovs.06-0201
-
(2006)
Invest Ophthalmol Vis Sci
, vol.47
, pp. 4444-4452
-
-
Meng, Q.1
Yang, P.2
Li, B.3
Zhou, H.4
Huang, X.5
Zhu, L.6
Ren, Y.7
Kijlstra, A.8
-
59
-
-
84870426866
-
INOS-selective inhibitors for cancer prevention: Promise and progress
-
PMID:23190107
-
Janakiram NB, Rao CV. iNOS-selective inhibitors for cancer prevention: Promise and progress. Future Med Chem 2012; 4:2193-204; PMID:23190107; http://dx.doi.org/10.4155/fmc.12.168
-
(2012)
Future Med Chem
, vol.4
, pp. 2193-2204
-
-
Janakiram, N.B.1
Rao, C.V.2
-
60
-
-
1642465558
-
Arginases I and II: Do their functions overlap?
-
PMID:15050972
-
Cederbaum SD, Yu H, Grody WW, Kern RM, Yoo P, Iyer RK. Arginases I and II: Do their functions overlap? Mol Genet Metab 2004; 81 Suppl 1:S38-44; PMID:15050972; http://dx.doi.org/10.1016/j.ymgme.2003.10.012
-
(2004)
Mol Genet Metab
, vol.81
, pp. S38-S44
-
-
Cederbaum, S.D.1
Yu, H.2
Grody, W.W.3
Kern, R.M.4
Yoo, P.5
Iyer, R.K.6
-
61
-
-
77955514968
-
Arginase 2 and nitric oxide synthase: Pathways associated with the pathogenesis of thyroid tumors
-
PMID:20542107
-
Sousa MS, Latini FR, Monteiro HP, Cerutti JM. Arginase 2 and nitric oxide synthase: Pathways associated with the pathogenesis of thyroid tumors. Free Radic Biol Med 2010; 49:997-1007; PMID:20542107; http://dx.doi.org/10.1016/j.freeradbiomed.2010.06.006
-
(2010)
Free Radic Biol Med
, vol.49
, pp. 997-1007
-
-
Sousa, M.S.1
Latini, F.R.2
Monteiro, H.P.3
Cerutti, J.M.4
-
62
-
-
84879159574
-
Myeloid-derived suppressor cells interact with tumors in terms of myelopoiesis, tumorigenesis and immunosuppression: Thick as thieves
-
PMID:23386900
-
Sevko A, Umansky V. Myeloid-derived suppressor cells interact with tumors in terms of myelopoiesis, tumorigenesis and immunosuppression: Thick as thieves. J Cancer 2013; 4:3-11; PMID:23386900; http://dx.doi.org/10.7150/jca.5047
-
(2013)
J Cancer
, vol.4
, pp. 3-11
-
-
Sevko, A.1
Umansky, V.2
-
63
-
-
67650917886
-
Expression of NADPH oxidase homologues and accessory genes in human cancer cell lines, tumours and adjacent normal tissues
-
PMID:19431059
-
Juhasz A, Ge Y, Markel S, Chiu A, Matsumoto L, van Balgooy J, Roy K, Doroshow JH. Expression of NADPH oxidase homologues and accessory genes in human cancer cell lines, tumours and adjacent normal tissues. Free Radic Res 2009; 43:523-32; PMID:19431059; http://dx.doi.org/10.1080/10715760902918683
-
(2009)
Free Radic Res
, vol.43
, pp. 523-532
-
-
Juhasz, A.1
Ge, Y.2
Markel, S.3
Chiu, A.4
Matsumoto, L.5
Van Balgooy, J.6
Roy, K.7
Doroshow, J.H.8
|