Excess secretion of gel-forming mucins and associated innate defense proteins with defective mucin un-packaging underpin gallbladder mucocele formation in dogs

PLoS ONE

Volumn 10, Issue 9, 2015, Pages

  Kesimer, Mehmet ^a   Cullen, John ^b   Cao, Rui ^a   Radicioni, Giorgia ^a   Mathews, Kyle G ^b   Seiler, Gabriela ^b   Gookin, Jody L ^b  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b NORTH CAROLINA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 1 ANTICHYMOTRYPSIN; ALPHA 1 ANTITRYPSIN; ALPHA 2 ANTIPLASMIN; BINDING PROTEIN; COMPLEMENT COMPONENT C1R; COMPLEMENT COMPONENT C1S; COMPLEMENT COMPONENT C3; COMPLEMENT COMPONENT C4A; COMPLEMENT COMPONENT C8; COMPLEMENT FACTOR H; COMPLEMENT FACTOR I; DELETED IN MALIGNANT BRAIN TUMORS 1; FIBRINOGEN; FIBRINOGEN LIKE 1; GALACTIN 3 BINDING PROTEIN; HEMOPEXIN; IGGFC BINDING PROTEIN; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; MUCIN 5AC; MUCIN 5B; PLASMINOGEN; PROTEIN; SECRETORY COMPONENT; SERUM ALBUMIN; SURFACTANT PROTEIN D; TREFOIL FACTOR III; UNCLASSIFIED DRUG; GEL;

ADOLESCENT; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOG; EXOCYTOSIS; GALLBLADDER EPITHELIUM; GALLBLADDER MUCOCELE; GEL FILTRATION CHROMATOGRAPHY; HISTOCHEMISTRY; MALE; MASS SPECTROMETRY; MUCOCELE; MUCUS; NONHUMAN; PROTEIN ANALYSIS; PROTEIN SECRETION; PROTEOMICS; ANIMAL; DIAGNOSTIC IMAGING; ECHOGRAPHY; EPITHELIUM; EPITHELIUM CELL; GALLBLADDER; GEL; GLYCOSYLATION; IMMUNOBLOTTING; INNATE IMMUNITY; METABOLISM; MUCOSA; PATHOLOGY; PHENOTYPE; RUPTURE; SECRETION (PROCESS); ULTRASTRUCTURE;

ANIMALS; DOGS; EPITHELIAL CELLS; EPITHELIUM; EXOCYTOSIS; GALLBLADDER; GELS; GLYCOSYLATION; IMMUNITY, INNATE; IMMUNOBLOTTING; MALE; MASS SPECTROMETRY; MUCIN 5AC; MUCIN-5B; MUCOCELE; MUCOUS MEMBRANE; MUCUS; PHENOTYPE; RUPTURE; ULTRASONOGRAPHY;

EID: 84946943837     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0138988     Document Type: Article

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