A Systematic RNAi Screen of Neuroprotective Genes Identifies Novel Modulators of Alpha-Synuclein-Associated Effects in Transgenic Caenorhabditis elegans

Molecular Neurobiology

Volumn 53, Issue 9, 2016, Pages 6288-6300

  Jadiya, Pooja ^a,b   Fatima, Soobiya ^b,c   Baghel, Tanvi ^b   Mir, Snober S ^c   Nazir, Aamir ^a,b  

^a ACADEMY OF SCIENTIFIC AND INNOVATIVE RESEARCH ACSIR   (India)

^b CENTRAL DRUG RESEARCH INSTITUTE   (India)

^c INTEGRAL UNIVERSITY   (India)

Author keywords

Alpha synuclein; Caenorhabditis elegans; Neuroprotective genes; Parkinson s disease

Indexed keywords

ACETYLCHOLINE; ALPHA SYNUCLEIN; CHOLINE KINASE; COLLAPSIN RESPONSE MEDIATOR PROTEIN; CYTOSKELETON PROTEIN; HISTONE DEMETHYLASE; LACTATE DEHYDROGENASE; LIPID; MESSENGER RNA; REACTIVE OXYGEN METABOLITE; SA PROTEIN; TRANSCRIPTION FACTOR DAF 16; UNCLASSIFIED DRUG; CAENORHABDITIS ELEGANS PROTEIN; DOPAMINE; PROTEIN AGGREGATE;

ACT 5 GENE; ARTICLE; BACTERIAL STRAIN; CAENORHABDITIS ELEGANS; CELL DEATH; CELL MOTILITY; CKA 2 GENE; COMPUTER MODEL; CYTOTOXICITY; DAF 16 GENE; DOPAMINERGIC SYSTEM; GENE; GENE EXPRESSION; GENE FUNCTION; GENE SILENCING; GENETIC ANALYSIS; GENETIC IDENTIFICATION; LDH 1 GENE; LOCOMOTION; MITOCHONDRION; NEUROPROTECTIVE GENE; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; OXIDATIVE STRESS; PARKINSON DISEASE; PATHOGENESIS; PROTEIN AGGREGATION; REAL TIME POLYMERASE CHAIN REACTION; RNA INTERFERENCE; RPS 0 GENE; SIGNAL TRANSDUCTION; SPR 5 GENE; TRANSGENIC ORGANISM; UNC 33 GENE; WORM; ANIMAL; CELL NUCLEUS; GENETICS; METABOLISM; NEUROPROTECTION; PROTEIN TRANSPORT; STAINING; TRANSGENIC ANIMAL;

ACETYLCHOLINE; ALPHA-SYNUCLEIN; ANIMALS; ANIMALS, GENETICALLY MODIFIED; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; CELL NUCLEUS; DOPAMINE; GENES, HELMINTH; LIPIDS; LOCOMOTION; MITOCHONDRIA; NEUROPROTECTION; PROTEIN AGGREGATES; PROTEIN TRANSPORT; REACTIVE OXYGEN SPECIES; RNA INTERFERENCE; SIGNAL TRANSDUCTION; STAINING AND LABELING;

EID: 84946924520     PISSN: 08937648     EISSN: 15591182     Source Type: Journal    
DOI: 10.1007/s12035-015-9517-3     Document Type: Article

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