Prevalence and predictors of sub-optimal medication adherence among patients with severe mental illnesses in a tertiary psychiatric facility in maiduguri, north-eastern nigeria

Pan African Medical Journal

Volumn 21, Issue , 2015, Pages

  Ibrahim, Abdu Wakawa ^a   Yahya, Shuaibu ^a   Pindar, Sadique Kwajafa ^a   Wakil, Musa Abba ^a   Garkuwa, Adamu ^b   Sale, Shehu ^c  

^a UNIVERSITY OF MAIDUGURI   (Nigeria)

^b ABUBAKAR TAFAWA BALEWA UNIVERSITY   (Nigeria)

^c BAYERO UNIVERSITY   (Nigeria)

Author keywords

Maiduguri; Mental illnesses; Nigeria; Sub optimal adherence

Indexed keywords

ADULT; AFRICAN MEDICINE; ALTERNATIVE MEDICINE; ARTICLE; ATTITUDE TO ILLNESS; BIPOLAR DISORDER; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DEPRESSION; DISEASE SEVERITY; FEMALE; GENDER; HELP SEEKING BEHAVIOR; HUMAN; MAJOR CLINICAL STUDY; MALE; MEDICATION COMPLIANCE; MENTAL HEALTH SERVICE; NIGERIA; PREVALENCE; SCHIZOPHRENIA; SOCIAL SUPPORT; TERTIARY CARE CENTER; ADOLESCENT; DEPRESSIVE DISORDER; MENTAL HOSPITAL; MIDDLE AGED; QUESTIONNAIRE; SEVERITY OF ILLNESS INDEX; STATISTICS AND NUMERICAL DATA; YOUNG ADULT;

ADOLESCENT; ADULT; BIPOLAR DISORDER; CROSS-SECTIONAL STUDIES; DEPRESSIVE DISORDER; FEMALE; HOSPITALS, PSYCHIATRIC; HUMANS; MALE; MEDICATION ADHERENCE; MIDDLE AGED; NIGERIA; PREVALENCE; SCHIZOPHRENIA; SEVERITY OF ILLNESS INDEX; SURVEYS AND QUESTIONNAIRES; YOUNG ADULT;

EID: 84946919559     PISSN: None     EISSN: 19378688     Source Type: Journal    
DOI: 10.11604/pamj.2015.21.39.6664     Document Type: Article

References (51)

1. Cook JA, Cohler BJ, Pickett SA, Beeler JA. Life course and severe mental illnesses: implications for care giving within the family of later life. Family Relations. 1997; 46(4):427-436. PubMed | Google Scholar
2. Bhugra D. Severe mental illness across cultures. Acta Psychiatr Scand. 2006; 113: (Suppl 429): 17-23. PubMed | Google Scholar
3. Thomas JL, Wilk JE, Riviere LA, McGurk D, Castro CA, Hoge CW. Prevalence of mental health problems and functional impairment among active components and national guard soldiers 3 and 12 months following combats in Iraq. Archives Gen Psychiatry. 2010; 67(6):614-623. PubMed | Google Scholar
4. Ustun B, Kennedy C. What is "functional impairment"? Disentangling disability from clinical significance. World Psychiatry. 2009; 8(2):82-85. PubMed | Google Scholar
5. McKnight PE, Kashdan TB. The importance of functional impairments to mental health outcomes: a case for reassessing our goals in depression treatment research. Clinical Psychology Review. 2009; 29: 243-259. PubMed | Google Scholar
6. Engel GL. The Clinical Application of the biopsychosocial model. The American Journal of Psychiatry. 1980; 137(5): 535-544. PubMed |Google Scholar
7. Mahaye S, Mayime T, Nkosi S, Mahomed FN et al. Medication adherence of psychiatric patients in an outpatient setting. African Journal of Pharmacy and Pharmacology. 2012; 6(9): 608-612.PubMed | Google Scholar
8. Sabaté E. Adherence to Long-Term Therapies. Evidence for action. Geneva, Switzerland: World Health Organization; 2003. Google Scholar
9. ABC Project Team. Ascertaining barriers for compliance: policies for safe, effective and cost-effective use of medicines in Europe. Final report of the ABC project. Available from: http://abcproject.eu/img/ABC%20Final.pdf. Accessed November 17, 2014. Google Scholar
10. Cramer JA, Roy A, Burrell A, Fairchild CJ et al. Medication compliance and persistence: terminology and definitions. Value Health. 2008; 11(1): 44-47. PubMed | Google Scholar
11. Hugtenburg JG, Timmers L, Elders PJM, Vervloet M, van Dijk L. Definitions, variants and causes of non-adherence with medication: a challenge for tailored interventions. Patient Preference and Adherence. 2013 July; 7: 675-682. PubMed | Google Scholar
12. Adams J, Scott J. Predicting medication adherence in severe mental disorders. Acta Psychiatr Scand. 2000; 101(2): 119-124. PubMed |Google Scholar
13. Dickson W, Kendall R. Does maintenance Lithium therapy prevent recurrences of mania under ordinary clinical conditions? Psychol Med. 1986; 16(3): 521 530. PubMed | Google Scholar
14. Demoz Z, Lagesse B, Teklay G, Demeke B, Eyob T et al. Medication adherence and its determinants among psychiatric patients in an Ethiopian referral hospital. Patient Preference and Adherence. 2041 Sept; 8: 1329-1335. PubMed | Google Scholar
15. DiMatteo MR, Giordani PJ, Lepper HS, Croghan TW. Patient adherence and medical treatment outcomes: a meta- analysis. Medical Care. 2002; 40(9): 794-811. PubMed | Google Scholar
16. Simpson SH, Eurich DT, Majumdar SR, Padwal RS et al. Ameta-analysis of the association between adherence to drug therapy and mortality. BMJ. 2006 July; 333(7557):15. PubMed | Google Scholar
17. Magura S, Rosenblum A, Fong C. Factors associated with medication adherence among psychiatric outpatients at substance abuse risk. Open Addict J. 2011 Nov; 4:58-64. PubMed | Google Scholar
18. Sun SX, Liu GG, Christensen DB, Fu AZ. Review and analysis of hospitalization costs associated with antipsychotic non-adherence in the treatment of schizophrenia in the United States. Curr Med Res Opin. 2007; 23(10): 2305-2312. PubMed | Google Scholar
19. American Pharmacists Association. Improving medication adherence among patients with severe mental illness. Pharmacy Today. 2013; 19(6): 69-80. PubMed | Google Scholar
20. Yang J, Ko YH, Paik JW, Lee MS et al. Symptom severity and attitudes towards medication: impacts on adherence in outpatients with schizophrenia. Schizophr Res. 2012; 134(3): 226-231. PubMed |Google Scholar
21. Kassis IT, Ghuloum S, Mousa H, Bener A. Treatment non-compliance of psychiatric patients; are patients satisfied from their psychiatrist? British Journal of Medicine and Medical Research. 2014; 4(2): 785-796. PubMed | Google Scholar
22. Lacro JP, Dunn LB, Dolder CR, Leckband SG, Jeste DV. Prevalence and risk factors for medication non-adherence in patients with schizophrenia: a comprehensive review of recent literature. J Clin Psychiatry. 2002 Oct; 63(10): 892-909. PubMed | Google Scholar
23. Higashi K, Medic G, Littlewood KJ, Diez T et al. Medication adherence in Schizophrenia: factors influencing adherence and consequences of non-adherence, a systematic literature review. Therapeutic Advances in Psychopharmacology. 2013; 3(4): 200-218. PubMed | Google Scholar
24. Haddad PM, Brain C, Scott J. Non-adherence with antipsychotic medications in schizophrenia: challenges and management strategies. Patient Related Outcome Measures. 2014 Jun; 5: 43-62. PubMed |Google Scholar
25. Lingam R, Scott J. Treatment non-adherence in affective disorders. Acta Psychiatr Scand. 2002; 105(3): 164-172. PubMed | Google Scholar
26. Sajatovic M, Valenstein M, Blow FC, Ganoczy D, Ignacio RV. Treatment adherence with lithium and anticonvulsant medications among patients with bipolar disorder. Psychiatr Serv. 2007; 58(6): 855-863. PubMed| Google Scholar
27. Sajatovic M, Valenstein M, Blow FC, Ganoczy D, Ignacio RV. Treatment adherence with antipsychotic medications in bipolar disorder. Bipolar Disorder. 2006; 8(3): 232-241. PubMed | Google Scholar
28. Stein-Shvachman IS, Karpas DS, Werner P. Depression treatment non-adherence and its psychosocial predictors: differences between young and older adults. Aging and Disease. 2013; 4(6): 329-336. PubMed |Google Scholar
29. Bosworth HB, Voils CI, Potter GG, Steffens DC. The effects of antidepressant medication adherence as well as psychosocial and clinical factors on depression outcome in older adults. Int J Geriatr Psych. 2008 Feb; 23(2): 129-134. PubMed | Google Scholar
30. Banerjee S, Varma RP. Factors affecting non-adherence among patients diagnosed with unipolar depression in a psychiatric department of a tertiary hospital in Kolkata, India. Depression Research and Treatment. 2013; Article Id 809542: 1-12. Google Scholar
31. Ten-Doesschate MC, Bockting CLH, Schene AH. Adherence to continuation and maintenance antidepressant use in recurrent depression. Journal of Affective Disorders. 2009 May; 115(1-2): 167-170. PubMed | Google Scholar
32. Kenfe T, Girma E, Negash A, Tesfaye M, Dehning S. Medication non-adherence among adult psychiatric outpatients in Jimma University Specialized Hospital, southwest Ethiopia. Ethiop J Health Sci. 2013; 23(3): 227-236. PubMed | Google Scholar
33. Amr M, El-Mogy A, El-Masry R. Adherence in Egyptian patients with schizophrenia: the role of insight, medication beliefs and spirituality. The Arab Journal of Psychiatry. 2013; 24(1): 60-68. PubMed |Google Scholar
34. Adewuya AO, Owoeye OA, Erinfolami AR, Coker AO et al. Prevalence and correlates of poor medication adherence amongst psychiatric patients in South-western Nigeria. Gen Hosp Psychiatry. 2009; 31(2): 167-174. PubMed | Google Scholar
35. Odo HO, Olotu SO, Agbonile IO, Esan PO et al. Assessment of adherence to psychotropic medications among outpatients at the pharmacy department of a psychiatric hospital, in Benin City, Nigeria. Asian J Pharm. 2014; 8(4): 211-215. PubMed | Google Scholar
36. Adeponle AB, Thombs BD, Adelekan ML, Kirmayer LJ. Family participation in treatment, post discharge appointment and medication adherence at a Nigerian psychiatric hospital. The British Journal of Psychiatry. 2009; 194(1): 86-87. PubMed | Google Scholar
37. Danladi J, Falang KD, Barde RA, Jimam NS et al. Pharmaceutical care and medication adherence in management of psychosis in a Nigerian tertiary hospital. Journal of Research in Pharmacy Practice. 2013; 2(2): 83-87. PubMed | Google Scholar
38. Boroffka A, Olatawura MO. Community psychiatry in Nigeria: the current status. International Journal of Social Psychiatry. 1977; 23(4): 275-281. PubMed | Google Scholar
39. Abiola T, Udofia O, Zakari M. Psychometric properties of the 3-item Oslo Social Support Scale among Clinical students of Bayero University, Kano, Nigeria. MJP Online. 2013; 22(2): 23-27. PubMed | Google Scholar
40. Dalgard OS, Dowrick C, Lehtinen V, Vazqez-Barquero JL et al. Negative life event, social support and gender difference in depression: a multidimensional community survey with data from the ODIN study. Soc Psychiatry Psychiatr Epidemiol. 2006; 41(6): 444-451. PubMed |Google Scholar
41. Morisky DE, Ang A, Krousel-Wood M, Ward H. Predictive validity of a Medication adherence measure for hypertension control. Journal of Clinical Hypertension. 2008; 10(5): 348-354. PubMed | Google Scholar
42. Kretchy IA, Owusu-Daaku FT, Danquah SA. Mental health in hypertension: assessing symptoms of anxiety, depression and stress on anti-hypertensive medication adherence. International Journal of Mental Health Systems. 2014; 8(25): 1-6. PubMed | Google Scholar
43. Verdoux H, Lengronne J, Liraud F, Gonzales B et al. Medication adherence in psychosis: predictors and impact on outcome: a 2-year follow-up of first-admitted subjects. Acta Psychiatr Scand. 2000 Sept; 102(3): 203-210. PubMed | Google Scholar
44. Fenton WS, Blyler CR, Heinssen RK. Determinants of medication compliance in schizophrenia: empirical and clinical findings. Schizophrenia Bulletin. 1997; 23(4): 637-651. PubMed | Google Scholar
45. Bolkan CR, Bonner LM, Campbell DG, Lanto A et al. Family involvement, medication adherence, and depression outcomes. Psychiatric Services. 2013; 64(5): 472-478. PubMed | Google Scholar
46. Rabinovitch M, Cassidy C, Schmitz N, Joober R, Malla A. The influence of perceived social support on medication adherence in first-episode psychosis. Can J Psychiatry. 2013; 58(1): 59-65. PubMed | Google Scholar
47. Razali SM, Yusoff MZ. Medication adherence in schizophrenia: a comparison between outpatients and relapse cases. East Asian Arch Psych. 2014 Sept; 24(2): 68-74. PubMed | Google Scholar
48. Yen CF, Chen CS, Ko CH, Yeh ML et al. Relationships between insight and medication adherence in outpatients with schizophrenia and bipolar disorder: prospective study. Psychiatry and Clinical Neurosciences. 2005; 59(4): 403-409. PubMed | Google Scholar
49. Lincoln TM, Lullman E, Rief W. Correlates and long-term consequences of poor insight in patients with schizophrenia: a systematic review. Schizophrenia Bull. 2007; 33(6): 1324-1342. PubMed | Google Scholar
50. Rocca P, Crivelli B, Marino F, Mongini T et al. Correlations of attitudes towards antipsychotic drugs with insight and objective psychopathology in schizophrenia. Compr Psychiatry. 2008 Mar - April; 49(2): 170-176. PubMed | Google Scholar
51. Mohamed S, Rosenheck R, McEvoy J, Swartz M et al. Cross-sectional and longitudinal relationships between insight and attitudes towards medication and clinical outcomes in chronic schizophrenia. Schizophr Bull. 2009 Mar; 35(2): 336-346. PubMed | Google Scholar