Berberine protects against light-induced photoreceptor degeneration in the mouse retina

Experimental Eye Research

Volumn 145, Issue , 2016, Pages 1-9

  Song, Delu ^a   Song, Jiantao ^a,b   Wang, Chenguang ^a,c   Li, Yafeng ^a   Dunaief, Joshua L ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b INSTITUTE OF CHINESE MATERIA MEDICA   (China)

^c THE SECOND HOSPITAL OF JILIN UNIVERSITY   (China)

Author keywords

Berberine; Light damage; Oxidative stress; Photoreceptor degeneration; Retina

Indexed keywords

ALLOGRAFT INFLAMMATORY FACTOR 1; BERBERINE; CATALASE; CERULOPLASMIN; COPPER ZINC SUPEROXIDE DISMUTASE; GLUTATHIONE PEROXIDASE 1; HEME OXYGENASE 1; MALONALDEHYDE; MANGANESE SUPEROXIDE DISMUTASE; MESSENGER RNA; MONOCARBOXYLATE TRANSPORTER 3; PROTEIN; RETINAL PIGMENT EPITHELIUM 65; RHODOPSIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL DEATH; CONTROLLED STUDY; DNA FRAGMENTATION; EYE PROTECTION; HISTOLOGY; IN VIVO STUDY; INFLAMMATION; MACROPHAGE; MALE; MICROGLIA; MOUSE; NEUROSENSORY RETINA; NONHUMAN; OPTICAL COHERENCE TOMOGRAPHY; OUTER NUCLEAR LAYER THICKNESS; OXIDATIVE STRESS; PHOTORECEPTOR DEGENERATION; PHOTORECEPTOR DISORGANIZATION; PHOTORECEPTOR THINNING; PIGMENT EPITHELIUM; PRIORITY JOURNAL; PROTEIN EXPRESSION; RETINA CONE; RETINA DEGENERATION; RETINA DISEASE; SENSORY NERVE CELL; TREATMENT DURATION; VISION; VISUAL SYSTEM PARAMETERS; ADVERSE EFFECTS; ANIMAL; BAGG ALBINO MOUSE; DISEASE MODEL; DRUG EFFECTS; ELECTRORETINOGRAPHY; LIGHT; METABOLISM; PATHOLOGY; RADIATION RESPONSE; RETINAL DEGENERATION; TUNEL ASSAY; VERTEBRATE PHOTORECEPTOR CELL;

ANIMALS; BERBERINE; CELL DEATH; DISEASE MODELS, ANIMAL; ELECTRORETINOGRAPHY; IN SITU NICK-END LABELING; LIGHT; MALE; MICE; MICE, INBRED BALB C; OXIDATIVE STRESS; PHOTORECEPTOR CELLS, VERTEBRATE; RETINAL DEGENERATION; RHODOPSIN; TOMOGRAPHY, OPTICAL COHERENCE;

EID: 84946833122     PISSN: 00144835     EISSN: 10960007     Source Type: Journal    
DOI: 10.1016/j.exer.2015.10.005     Document Type: Article

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