Role of PUMA in methamphetamine-induced neuronal apoptosis

Toxicology Letters

Volumn 240, Issue 1, 2016, Pages 149-160

  Chen, Chuanxiang ^a   Qincao, Litao ^a   Xu, Jingtao ^a   Du, Sihao ^a   Huang, Enping ^a   Liu, Chao ^b   Lin, Zhoumeng ^c   Xie, Wei Bing ^a   Wang, Huijun ^a  

^a SOUTHERN MEDICAL UNIVERSITY   (China)

^b Guangzhou Forensic Science Institute   (China)

^c KANSAS STATE UNIVERSITY   (United States)

Author keywords

Apoptosis; Methamphetamine; Neurotoxicity; PUMA (p53 upregulated modulator of apoptosis)

Indexed keywords

CASPASE 3; CYTOCHROME C; METHAMPHETAMINE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BAX; PROTEIN BCL 2; PUMA PROTEIN; SMALL INTERFERING RNA; APOPTOSIS REGULATORY PROTEIN; BAX PROTEIN, HUMAN; BAX PROTEIN, RAT; BBC3 PROTEIN, HUMAN; CASP3 PROTEIN, HUMAN; CASP3 PROTEIN, RAT; ONCOPROTEIN; PUMA PROTEIN, RAT;

ANIMAL CELL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; CYTOPLASM; ENZYME ACTIVATION; FLOW CYTOMETRY; GENE SILENCING; HUMAN; HUMAN CELL; IN VITRO STUDY; INTRACELLULAR SIGNALING; MITOCHONDRION; NERVE CELL NECROSIS; NONHUMAN; PC12 CELL LINE; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; RAT; RNA INTERFERENCE; TUNEL ASSAY; WESTERN BLOTTING; ANIMAL; DOWN REGULATION; DRUG EFFECTS; GENETICS; METABOLISM; NERVE CELL; TUMOR CELL LINE; UPREGULATION;

ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; BCL-2-ASSOCIATED X PROTEIN; CASPASE 3; CELL LINE, TUMOR; CYTOCHROMES C; CYTOPLASM; DOWN-REGULATION; GENE SILENCING; HUMANS; IN SITU NICK-END LABELING; METHAMPHETAMINE; MITOCHONDRIA; NEURONS; PC12 CELLS; PROTO-ONCOGENE PROTEINS; RATS; RNA, SMALL INTERFERING; UP-REGULATION;

EID: 84946771293     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2015.10.020     Document Type: Article

References (30)

1. World Drug Report, 2014. World Drug Report 2014 of United Nations Office on Drugs and Crime.
2. Biswas S.C., Ryu E., Park C., Malagelada C., Greene L.A. Puma and p53 play required roles in death evoked in a cellular model of Parkinson disease. Neurochem. Res. 2005, 30:839-845.
3. Callaghan R.C., Cunningham J.K., Sykes J., Kish S.J. Increased risk of Parkinson's disease in individuals hospitalized with conditions related to the use of methamphetamine or other amphetamine-type drugs. Drug Alcohol Depend. 2012, 120:35-40.
4. Chen H., Tian M., Jin L., Jia H., Jin Y. PUMA is invovled in ischemia/reperfusion-induced apoptosis of mouse cerebral astrocytes. Neuroscience 2015, 284:824-832.
5. Chipuk J.E., Moldoveanu T., Llambi F., Parsons M.J., Green D.R. The BCL-2 family reunion. Mol. Cell 2010, 37:299-310.
6. Deng X., Cai N.S., McCoy M.T., Chen W., Trush M.A., Cadet J.L. Methamphetamine induces apoptosis in an immortalized rat striatal cell line by activating the mitochondrial cell death pathway. Neuropharmacology 2002, 42:837-845.
7. Deng X., Ladenheim B., Jayanthi S., Cadet J.L. Methamphetamine administration causes death of dopaminergic neurons in the mouse olfactory bulb. Biol. Psychiatry 2007, 61:1235-1243.
8. Gulbins E., Dreschers S., Bock J. Role of mitochondria in apoptosis. Exp. Physiol. 2003, 88:85-90.
9. Harder J.M., Libby R.T. BBC3 (PUMA) regulates developmental apoptosis but not axonal injury induced death in the retina. Mol. Neurodegener. 2011, 6:50.
10. Huang W., Xie W.B., Qiao D., Qiu P., Huang E., Li B., Chen C., Liu C., Wang Q., Lin Z., Wang H. Caspase-11 plays an essential role in methamphetamine-induced dopaminergic neuron apoptosis. Toxicol. Sci. 2015, 145:68-79.
11. Kim H., Tu H.C., Ren D., Takeuchi O., Jeffers J.R., Zambetti G.P., Hsieh J.J., Cheng E.H. Stepwise activation of BAX and BAK by tBID, BIM, and PUMA initiates mitochondrial apoptosis. Mol. Cell 2009, 36:487-499.
12. Kuwana T., Bouchier-Hayes L., Chipuk J.E., Bonzon C., Sullivan B.A., Green D.R., Newmeyer D.D. BH3 domains of BH3-only proteins differentially regulate Bax-mediated mitochondrial membrane permeabilization both directly and indirectly. Mol. Cell 2005, 17:525-535.
13. Li J.P., Yang Y.X., Liu Q.L., Pan S.T., He Z.X., Zhang X., Yang T., Chen X.W., Wang D., Qiu J.X., Zhou S.F. The investigational Aurora kinase A inhibitor alisertib (MLN8237) induces cell cycle G2/M arrest, apoptosis, and autophagy via p38 MAPK and Akt/mTOR signaling pathways in human breast cancer cells. Drug Des. Dev. Ther. 2015, 9:1627-1652.
14. Lotharius J., Barg S., Wiekop P., Lundberg C., Raymon H.K., Brundin P. Effect of mutant alpha-synuclein on dopamine homeostasis in a new human mesencephalic cell line. J. Biol. Chem. 2002, 277:38884-38894.
15. Milane L., Trivedi M., Singh A., Talekar M., Amiji M. Mitochondrial biology, targets, and drug delivery. J. Control. Release 2015, 207:40-58.
16. Mohan N., Banik N.L., Ray S.K. Synergistic efficacy of a novel combination therapy controls growth of Bcl-x(L) bountiful neuroblastoma cells by increasing differentiation and apoptosis. Cancer Biol. Ther. 2011, 12:846-854.
17. Nakano K., Vousden K.H. PUMA, a novel proapoptotic gene, is induced by p53. Mol. Cell 2001, 7:683-694.
18. Ouyang Y.B., Xu L., Lu Y., Sun X., Yue S., Xiong X.X., Giffard R.G. Astrocyte-enriched miR-29a targets PUMA and reduces neuronal vulnerability to forebrain ischemia. Glia 2013, 61:1784-1794.
19. Qiao D., Xu J., Le C., Huang E., Liu C., Qiu P., Lin Z., Xie W.B., Wang H. Insulin-like growth factor binding protein 5 (IGFBP5) mediates methamphetamine-induced dopaminergic neuron apoptosis. Toxicol. Lett. 2014, 230:444-453.
20. Johnstone Ricky W., Ruefli A.A., Lowe Scott W. Apoptosis: a link between cancer genetics and chemotherapy. Cell 2002, 108:153-164.
21. Speen A., Jones C., Patel R., Shah H., Nallasamy P., Brooke E.A., Zhu H., Li Y.R., Jia Z. Mechanisms of CDDO-imidazolide-mediated cytoprotection against acrolein-induced neurocytotoxicity in SH-SY5Y cells and primary human astrocytes. Toxicol. Lett. 2015, 238:32-42.
22. Steckley D., Karajgikar M., Dale L.B., Fuerth B., Swan P., Drummond-Main C., Poulter M.O., Ferguson S.S., Strasser A., Cregan S.P. Puma is a dominant regulator of oxidative stress induced Bax activation and neuronal apoptosis. J. Neurosci. 2007, 27:12989-12999.
23. Vavrova J., Rezacova M. Importance of proapoptotic protein PUMA in cell radioresistance. Folia Biol. 2014, 60:53-56.
24. Wang K., Fu X.Y., Fu X.T., Hou Y.J., Fang J., Zhang S., Yang M.F., Li D.W., Mao L.L., Sun J.Y., Yuan H., Yang X.Y., Fan C.D., Zhang Z.Y., Sun B.L. DSePA antagonizes high glucose-induced neurotoxicity: evidences for DNA damage-mediated p53 phosphorylation and MAPKs and AKT pathways. Mol. Neurobiol. 2015.
25. Westphal D., Dewson G., Czabotar P.E., Kluck R.M. Molecular biology of Bax and Bak activation and action. Biochim. Biophys. Acta 2011, 1813:521-531.
26. Wu C.W., Ping Y.H., Yen J.C., Chang C.Y., Wang S.F., Yeh C.L., Chi C.W., Lee H.C. Enhanced oxidative stress and aberrant mitochondrial biogenesis in human neuroblastoma SH-SY5Y cells during methamphetamine induced apoptosis. Toxicol. Appl. Pharmacol. 2007, 220:243-251.
27. Wu F., Zheng Y., Gao J., Chen S., Wang Z. Induction of oxidative stress and the transcription of genes related to apoptosis in rare minnow (Gobiocypris rarus) larvae with Aroclor 1254 exposure. Ecotoxicol. Environ. Saf. 2014, 110:254-260.
28. Yang L.Y., Chu Y.H., Tweedie D., Yu Q.S., Pick C.G., Hoffer B.J., Greig N.H., Wang J.Y. Post-trauma administration of the pifithrin-alpha oxygen analog improves histological and functional outcomes after experimental traumatic brain injury. Exp. Neurol. 2015, 269:56-66.
29. Yu J., Zhang L. PUMA, a potent killer with or without p53. Oncogene 2008, 27(Suppl. 1):S71-S83.
30. Zhang X., Lu H., Wang Y., Liu C., Zhu W., Zheng S., Wan F. Taurine induces the apoptosis of breast cancer cells by regulating apoptosis-related proteins of mitochondria. Int. J. Mol. Med. 2015, 35:218-226.