Insulin-like growth factor binding protein 5 (IGFBP5) mediates methamphetamine-induced dopaminergic neuron apoptosis

Toxicology Letters

Volumn 230, Issue 3, 2014, Pages 444-453

  Qiao, Dongfang ^a   Xu, Jingtao ^a   Le, Cuiyun ^a   Huang, Enping ^a   Liu, Chao ^b   Qiu, Pingming ^a   Lin, Zhoumeng ^c,d   Xie, Wei Bing ^a   Wang, Huijun ^a  

^a SOUTHERN MEDICAL UNIVERSITY   (China)

^b Guangzhou Forensic Science Institute   (China)

^c UNIVERSITY OF GEORGIA   (United States)

^d KANSAS STATE UNIVERSITY   (United States)

Author keywords

Apoptosis; Insulin like growth factor binding protein 5 (IGFBP5); Methamphetamine (METH); Neurotoxicity

Indexed keywords

CASPASE 3; CYTOCHROME C; MESSENGER RNA; METHAMPHETAMINE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN; SOMATOMEDIN BINDING PROTEIN 5; CASP3 PROTEIN, RAT; LIPOCORTIN 5;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN MITOCHONDRION; CELL ACTIVITY; CELL COUNT; CONTROLLED STUDY; CORPUS STRIATUM; DOPAMINERGIC NERVE CELL; FLOW CYTOMETRY; GENE EXPRESSION; GENE SILENCING; MALE; NEUROTOXICITY; NICK END LABELING; NONHUMAN; PC12 CELL LINE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SECRETION; RAT; WESTERN BLOTTING; ANIMAL; ANTAGONISTS AND INHIBITORS; CYTOPLASM; DOSE RESPONSE; DRUG EFFECTS; ENZYME LINKED IMMUNOSORBENT ASSAY; METABOLISM; MITOCHONDRION; NEUROTOXICITY SYNDROMES; PATHOLOGY; SPRAGUE DAWLEY RAT; TOXICITY; UPREGULATION;

ANIMALS; ANNEXIN A5; APOPTOSIS; CASPASE 3; CORPUS STRIATUM; CYTOCHROMES C; CYTOPLASM; DOPAMINERGIC NEURONS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE SILENCING; IN SITU NICK-END LABELING; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 5; MALE; METHAMPHETAMINE; MITOCHONDRIA; NEUROTOXICITY SYNDROMES; PC12 CELLS; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; UP-REGULATION;

EID: 84910028846     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2014.08.010     Document Type: Article

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