NH125 reduces the level of CPEB3, an RNA binding protein, to promote synaptic GluA2 expression

Neuropharmacology

Volumn 101, Issue , 2016, Pages 531-537

  Bender, Crhistian L ^a   Yang, Qian ^a   Sun, Lu ^a   Liu, Siqiong June ^a  

^a LOUISIANA STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

AMPA receptors; Cerebellum; CPEB3; eEF2; eEF2 kinase; GluA2; Interneurons; NH125; Protein synthesis

Indexed keywords

ELONGATION FACTOR 2 KINASE; GLUTAMATE RECEPTOR 2; MESSENGER RNA; PROTEIN CPEB3; RNA BINDING PROTEIN; UNCLASSIFIED DRUG; A-484954; AMPA RECEPTOR; CPEB3 PROTEIN, MOUSE; GLUTAMATE DECARBOXYLASE; GLUTAMATE DECARBOXYLASE 2; GLUTAMATE RECEPTOR IONOTROPIC, AMPA 2; GREEN FLUORESCENT PROTEIN; IMIDAZOLE DERIVATIVE; NH 125; PYRIDINE DERIVATIVE; PYRIMIDINE DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN NERVE CELL; CEREBELLUM; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; GENE EXPRESSION; GLUA2 GENE; IMMUNOREACTIVITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; STELLATE CELL; SYNAPTIC TRANSMISSION; ANIMAL; CELL CULTURE; CYTOLOGY; DOSE RESPONSE; DRUG EFFECTS; ELECTROSTIMULATION; EXCITATORY POSTSYNAPTIC POTENTIAL; GENE EXPRESSION REGULATION; GENETICS; IN VITRO STUDY; METABOLISM; NERVE CELL; NEWBORN; PATCH CLAMP TECHNIQUE;

ANIMALS; ANIMALS, NEWBORN; CELLS, CULTURED; CEREBELLUM; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRIC STIMULATION; EXCITATORY POSTSYNAPTIC POTENTIALS; GENE EXPRESSION REGULATION; GLUTAMATE DECARBOXYLASE; GREEN FLUORESCENT PROTEINS; IMIDAZOLES; IN VITRO TECHNIQUES; MICE; NEURONS; PATCH-CLAMP TECHNIQUES; PYRIDINES; PYRIMIDINES; RECEPTORS, AMPA; RNA-BINDING PROTEINS;

EID: 84946595267     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2015.03.017     Document Type: Article

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