Camphene isolated from essential oil of Piper cernuum (Piperaceae) induces intrinsic apoptosis in melanoma cells and displays antitumor activity in vivo

Biochemical and Biophysical Research Communications

Volumn 467, Issue 4, 2015, Pages 928-934

  Girola, Natalia ^a   Figueiredo, Carlos R ^a   Farias, Camyla F ^a   Azevedo, Ricardo A ^b   Ferreira, Adilson K ^b   Teixeira, Sarah F ^b   Capello, Tabata M ^a   Martins, Euder G A ^b   Matsuo, Alisson L ^a   Travassos, Luiz R ^a   Lago, João H G ^a  

^a FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Antitumor; Apoptosis; Camphene; Melanoma

Indexed keywords

CALCIUM; CALRETICULIN; CAMPHENE; CASPASE 3; CISPLATIN; ESSENTIAL OIL; HIGH MOBILITY GROUP B1 PROTEIN; PETROLEUM; ANTINEOPLASTIC AGENT; TERPENE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CALCIUM TRANSPORT; CELL STRUCTURE; CHROMATIN CONDENSATION; CONTROLLED STUDY; DNA DEGRADATION; DRUG CYTOTOXICITY; DRUG ISOLATION; DRUG MECHANISM; DRUG STRUCTURE; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IC50; IN VITRO STUDY; IN VIVO STUDY; MALE; MELANOMA; MELANOMA CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; MOUSE; NONHUMAN; PIPER (PLANT); PIPER CERNUUM; PLANT LEAF; PRIORITY JOURNAL; UPREGULATION; ANIMAL; CHEMISTRY; DRUG EFFECTS; ENDOPLASMIC RETICULUM; MELANOMA, EXPERIMENTAL; METABOLISM; PATHOLOGY; TUMOR CELL LINE;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CALCIUM; CALRETICULIN; CELL LINE, TUMOR; ENDOPLASMIC RETICULUM; HUMANS; MELANOMA, EXPERIMENTAL; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; PIPER; TERPENES;

EID: 84946595039     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2015.10.041     Document Type: Article

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