RNA-Seq of Tumor-Educated Platelets Enables Blood-Based Pan-Cancer, Multiclass, and Molecular Pathway Cancer Diagnostics

Cancer Cell

Volumn 28, Issue 5, 2015, Pages 666-676

  Best, Myron G ^a   Sol, Nik ^a   Kooi, Irsan ^a   Tannous, Jihane ^b   Westerman, Bart A ^a   Rustenburg, François ^a   Schellen, Pepijn ^a,c   Verschueren, Heleen ^a,c   Post, Edward ^a,c   Koster, Jan ^d   Ylstra, Bauke ^a   Ameziane, Najim ^a   Dorsman, Josephine ^a   Smit, Egbert F ^a   Verheul, Henk M ^a   Noske, David P ^a   Reijneveld, Jaap C ^a   Nilsson, R Jonas A ^a,c,e   Tannous, Bakhos A ^b   Wesseling, Pieter ^a,f   Wurdinger, Thomas ^a,b,c   more..

^a VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^b HARVARD MEDICAL SCHOOL   (United States)

^c Academic Medical Center ^*  (Netherlands)

^d ACADEMIC MEDICAL CENTER   (Netherlands)

^e UMEÅ UNIVERSITY   (Sweden)

^f RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; EPIDERMAL GROWTH FACTOR RECEPTOR; K RAS PROTEIN; MESSENGER RNA; PHOSPHATIDYLINOSITOL 3 KINASE; EGFR PROTEIN, HUMAN; EPIDERMAL GROWTH FACTOR RECEPTOR 2; KRAS PROTEIN, HUMAN; MET PROTEIN, HUMAN; PIK3CA PROTEIN, HUMAN; PROTEIN P21; SCATTER FACTOR RECEPTOR; TUMOR MARKER;

ARTICLE; CANCER DIAGNOSIS; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; RNA SEQUENCE; SEQUENCE ANALYSIS; THROMBOCYTE; TUMOR BIOPSY; TUMOR EDUCATED PLATELET; ADULT; AGED; BLOOD; FEMALE; GENE EXPRESSION PROFILING; GENE ONTOLOGY; GENETICS; MALE; METABOLISM; MIDDLE AGED; MOLECULAR PATHOLOGY; MUTATION; NEOPLASMS; PROCEDURES; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY; SIGNAL TRANSDUCTION; SUPPORT VECTOR MACHINE; VERY ELDERLY; YOUNG ADULT;

ADULT; AGED; AGED, 80 AND OVER; BIOMARKERS, TUMOR; BLOOD PLATELETS; FEMALE; GENE EXPRESSION PROFILING; GENE ONTOLOGY; HUMANS; MALE; MIDDLE AGED; MUTATION; NEOPLASMS; PATHOLOGY, MOLECULAR; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-MET; PROTO-ONCOGENE PROTEINS P21(RAS); RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTOR, ERBB-2; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SEQUENCE ANALYSIS, RNA; SIGNAL TRANSDUCTION; SUPPORT VECTOR MACHINE; YOUNG ADULT;

EID: 84946568126     PISSN: 15356108     EISSN: 18783686     Source Type: Journal    
DOI: 10.1016/j.ccell.2015.09.018     Document Type: Article

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