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Volumn 109, Issue 11, 2015, Pages 1404-1409

Persistent airflow obstruction in patients with asthma: Characteristics of a distinct clinical phenotype

Author keywords

Airways inflammation; Asthma; Cluster analysis; Persistent airflow obstruction; Phenotype

Indexed keywords

BETA ADRENERGIC RECEPTOR STIMULATING AGENT; CORTICOSTEROID; LEUKOTRIENE RECEPTOR BLOCKING AGENT; METHACHOLINE; NITRIC OXIDE; OMALIZUMAB; BRONCHODILATING AGENT; GLUCOCORTICOID;

EID: 84946566999     PISSN: 09546111     EISSN: 15323064     Source Type: Journal    
DOI: 10.1016/j.rmed.2015.09.009     Document Type: Article
Times cited : (43)

References (25)
  • 2
    • 33747756534 scopus 로고    scopus 로고
    • Asthma: Defining of the persistent adult phenotypes
    • S.E. Wenzel Asthma: defining of the persistent adult phenotypes Lancet 368 9537 2006 804 813
    • (2006) Lancet , vol.368 , Issue.9537 , pp. 804-813
    • Wenzel, S.E.1
  • 3
    • 52049087356 scopus 로고    scopus 로고
    • Endotyping asthma: New insights into key pathogenic mechanisms in a complex, heterogeneous disease
    • G.P. Anderson Endotyping asthma: new insights into key pathogenic mechanisms in a complex, heterogeneous disease Lancet 372 9643 2008 1107 1119
    • (2008) Lancet , vol.372 , Issue.9643 , pp. 1107-1119
    • Anderson, G.P.1
  • 4
    • 84878772362 scopus 로고    scopus 로고
    • Identification of asthma clusters in two independent Korean adult asthma cohorts
    • T.B. Kim, A.S. Jang, H.S. Kwon, J.S. Park, Y.S. Chang, S.H. Cho, and et al. Identification of asthma clusters in two independent Korean adult asthma cohorts Eur. Respir. J. 41 6 2013 1308 1314
    • (2013) Eur. Respir. J. , vol.41 , Issue.6 , pp. 1308-1314
    • Kim, T.B.1    Jang, A.S.2    Kwon, H.S.3    Park, J.S.4    Chang, Y.S.5    Cho, S.H.6
  • 6
    • 0034526865 scopus 로고    scopus 로고
    • Proceedings of the ATS workshop on refractory asthma: Current understanding, recommendations, and unanswered questions
    • Proceedings of the ATS workshop on refractory asthma: current understanding, recommendations, and unanswered questions Am. Thoracic Soc. Am. J. Respir. Crit. Care Med. 162 6 2000 2341 2351
    • (2000) Am. Thoracic Soc. Am. J. Respir. Crit. Care Med. , vol.162 , Issue.6 , pp. 2341-2351
  • 7
    • 80052829963 scopus 로고    scopus 로고
    • Diagnosis and definition of severe refractory asthma: An international consensus statement from the Innovative Medicine Initiative (IMI)
    • E.H. Bel, A. Sousa, L. Fleming, A. Bush, K.F. Chung, J. Versnel, and et al. Diagnosis and definition of severe refractory asthma: an international consensus statement from the Innovative Medicine Initiative (IMI) Thorax 66 10 2011 910 917
    • (2011) Thorax , vol.66 , Issue.10 , pp. 910-917
    • Bel, E.H.1    Sousa, A.2    Fleming, L.3    Bush, A.4    Chung, K.F.5    Versnel, J.6
  • 8
    • 67649224092 scopus 로고    scopus 로고
    • Airway remodeling in subjects with severe asthma with or without chronic persistent airflow obstruction
    • e1-4
    • M. Kaminska, S. Foley, K. Maghni, C. Storness-Bliss, H. Coxson, H. Ghezzo, and et al. Airway remodeling in subjects with severe asthma with or without chronic persistent airflow obstruction J. Allergy Clin. Immunol. 124 1 2009 45 51 e1-4
    • (2009) J. Allergy Clin. Immunol. , vol.124 , Issue.1 , pp. 45-51
    • Kaminska, M.1    Foley, S.2    Maghni, K.3    Storness-Bliss, C.4    Coxson, H.5    Ghezzo, H.6
  • 9
    • 37549020054 scopus 로고    scopus 로고
    • Risk factors associated with persistent airflow limitation in severe or difficult-to-treat asthma: Insights from the TENOR study
    • J.H. Lee, T. Haselkorn, L. Borish, L. Rasouliyan, B.E. Chipps, and S.E. Wenzel Risk factors associated with persistent airflow limitation in severe or difficult-to-treat asthma: insights from the TENOR study Chest 132 6 2007 1882 1889
    • (2007) Chest , vol.132 , Issue.6 , pp. 1882-1889
    • Lee, J.H.1    Haselkorn, T.2    Borish, L.3    Rasouliyan, L.4    Chipps, B.E.5    Wenzel, S.E.6
  • 10
    • 84871989312 scopus 로고    scopus 로고
    • Persistent airway obstruction in asthma
    • P. Lange Persistent airway obstruction in asthma Am. J. Respir. Crit. Care Med. 187 1 2013 1 2
    • (2013) Am. J. Respir. Crit. Care Med. , vol.187 , Issue.1 , pp. 1-2
    • Lange, P.1
  • 11
    • 84871958002 scopus 로고    scopus 로고
    • The interplay between the effects of lifetime asthma, smoking, and atopy on fixed airflow obstruction in middle age
    • J.L. Perret, S.C. Dharmage, M.C. Matheson, D.P. Johns, L.C. Gurrin, J.A. Burgess, and et al. The interplay between the effects of lifetime asthma, smoking, and atopy on fixed airflow obstruction in middle age Am. J. Respir. Crit. Care Med. 187 1 2013 42 48
    • (2013) Am. J. Respir. Crit. Care Med. , vol.187 , Issue.1 , pp. 42-48
    • Perret, J.L.1    Dharmage, S.C.2    Matheson, M.C.3    Johns, D.P.4    Gurrin, L.C.5    Burgess, J.A.6
  • 12
    • 84857194016 scopus 로고    scopus 로고
    • Increased levels of angiopoietins 1 and 2 in sputum supernatant in severe refractory asthma
    • E. Tseliou, P. Bakakos, K. Kostikas, G. Hillas, K. Mantzouranis, P. Emmanouil, and et al. Increased levels of angiopoietins 1 and 2 in sputum supernatant in severe refractory asthma Allergy 67 3 2012 396 402
    • (2012) Allergy , vol.67 , Issue.3 , pp. 396-402
    • Tseliou, E.1    Bakakos, P.2    Kostikas, K.3    Hillas, G.4    Mantzouranis, K.5    Emmanouil, P.6
  • 14
    • 0032020479 scopus 로고    scopus 로고
    • Methods for sputum induction and analysis of induced sputum: A method for assessing airway inflammation in asthma
    • J.C. Kips, J.V. Fahy, F.E. Hargreave, P.W. Ind, and J.C. in't Veen Methods for sputum induction and analysis of induced sputum: a method for assessing airway inflammation in asthma Eur. Respir. J. Suppl. 26 1998 9S 12S
    • (1998) Eur. Respir. J. Suppl. , vol.26 , pp. 9S-12S
    • Kips, J.C.1    Fahy, J.V.2    Hargreave, F.E.3    Ind, P.W.4    In'T Veen, J.C.5
  • 15
    • 0032961683 scopus 로고    scopus 로고
    • Induced sputum in adolescents with severe stable asthma. Safety and the relationship of cell counts and eosinophil cationic protein to clinical severity
    • D.C. Grootendorst, J.W. van den Bos, J.J. Romeijn, M. Veselic-Charvat, E.J. Duiverman, E.J. Vrijlandt, and et al. Induced sputum in adolescents with severe stable asthma. Safety and the relationship of cell counts and eosinophil cationic protein to clinical severity Eur. Respir. J. 13 3 1999 647 653
    • (1999) Eur. Respir. J. , vol.13 , Issue.3 , pp. 647-653
    • Grootendorst, D.C.1    Van Den Bos, J.W.2    Romeijn, J.J.3    Veselic-Charvat, M.4    Duiverman, E.J.5    Vrijlandt, E.J.6
  • 16
    • 0029090616 scopus 로고
    • Standardization of Spirometry, 1994 update
    • Standardization of Spirometry, 1994 update Am. Thoracic Soc. Am. J. Respir. Crit. Care Med. 152 3 1995 1107 1136
    • (1995) Am. Thoracic Soc. Am. J. Respir. Crit. Care Med. , vol.152 , Issue.3 , pp. 1107-1136
  • 17
    • 0033966788 scopus 로고    scopus 로고
    • Guidelines for methacholine and exercise challenge testing-1999. This official statement of the American Thoracic Society was adopted by the ATS Board of Directors, July 1999
    • R.O. Crapo, R. Casaburi, A.L. Coates, P.L. Enright, J.L. Hankinson, C.G. Irvin, and et al. Guidelines for methacholine and exercise challenge testing-1999. This official statement of the American Thoracic Society was adopted by the ATS Board of Directors, July 1999 Am. J. Respir. Crit. Care Med. 161 1 2000 309 329
    • (2000) Am. J. Respir. Crit. Care Med. , vol.161 , Issue.1 , pp. 309-329
    • Crapo, R.O.1    Casaburi, R.2    Coates, A.L.3    Enright, P.L.4    Hankinson, J.L.5    Irvin, C.G.6
  • 18
    • 17644363081 scopus 로고    scopus 로고
    • ATS/ERS recommendations for standardized procedures for the online and offline measurement of exhaled lower respiratory nitric oxide and nasal nitric oxide, 2005
    • ATS/ERS recommendations for standardized procedures for the online and offline measurement of exhaled lower respiratory nitric oxide and nasal nitric oxide, 2005 Am. J. Respir. Crit. Care Med. 171 8 2005 912 930
    • (2005) Am. J. Respir. Crit. Care Med. , vol.171 , Issue.8 , pp. 912-930
  • 21
    • 76149146032 scopus 로고    scopus 로고
    • Identification of asthma phenotypes using cluster analysis in the severe asthma research program
    • W.C. Moore, D.A. Meyers, S.E. Wenzel, W.G. Teague, H. Li, X. Li, and et al. Identification of asthma phenotypes using cluster analysis in the severe asthma research program Am. J. Respir. Crit. Care Med. 181 4 2010 315 323
    • (2010) Am. J. Respir. Crit. Care Med. , vol.181 , Issue.4 , pp. 315-323
    • Moore, W.C.1    Meyers, D.A.2    Wenzel, S.E.3    Teague, W.G.4    Li, H.5    Li, X.6
  • 22
    • 84904876327 scopus 로고    scopus 로고
    • Statistical cluster analysis of the British thoracic society severe refractory asthma registry: Clinical outcomes and phenotype stability
    • C. Newby, L.G. Heaney, A. Menzies-Gow, R.M. Niven, A. Mansur, C. Bucknall, and et al. Statistical cluster analysis of the British thoracic society severe refractory asthma registry: clinical outcomes and phenotype stability PLoS One 9 7 2014 e102987
    • (2014) PLoS One , vol.9 , Issue.7 , pp. e102987
    • Newby, C.1    Heaney, L.G.2    Menzies-Gow, A.3    Niven, R.M.4    Mansur, A.5    Bucknall, C.6
  • 23
    • 84862794930 scopus 로고    scopus 로고
    • Air trapping is a major determinant of persistent airway obstruction in asthmatics
    • S.W. Park, J.S. Park, S.H. Jeong, Y.N. Lee, Y. Hwangbo, J.H. Lee, and et al. Air trapping is a major determinant of persistent airway obstruction in asthmatics Respir. Med. 106 6 2012 786 793
    • (2012) Respir. Med. , vol.106 , Issue.6 , pp. 786-793
    • Park, S.W.1    Park, J.S.2    Jeong, S.H.3    Lee, Y.N.4    Hwangbo, Y.5    Lee, J.H.6
  • 24
    • 84907048189 scopus 로고    scopus 로고
    • Risk factors associated with irreversible airway obstruction in nonsmoking adult patients with severe asthma
    • M. Ciebiada, M. Domagala, M. Gorska-Ciebiada, and P. Gorski Risk factors associated with irreversible airway obstruction in nonsmoking adult patients with severe asthma Allergy Asthma Proc. 35 5 2014 72 79
    • (2014) Allergy Asthma Proc. , vol.35 , Issue.5 , pp. 72-79
    • Ciebiada, M.1    Domagala, M.2    Gorska-Ciebiada, M.3    Gorski, P.4
  • 25
    • 84939244162 scopus 로고    scopus 로고
    • Unraveling the pathophysiology of the asthma-COPD overlap syndrome: Unsuspected mild centrilobular emphysema is responsible for loss of lung elastic recoil in never smokers with asthma with persistent expiratory airflow limitation
    • A.F. Gelb, A. Yamamoto, E.K. Verbeken, and J.A. Nadel Unraveling the pathophysiology of the asthma-COPD overlap syndrome: unsuspected mild centrilobular emphysema is responsible for loss of lung elastic recoil in never smokers with asthma with persistent expiratory airflow limitation Chest 148 2 2015 313 320
    • (2015) Chest , vol.148 , Issue.2 , pp. 313-320
    • Gelb, A.F.1    Yamamoto, A.2    Verbeken, E.K.3    Nadel, J.A.4


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