메뉴 건너뛰기




Volumn 51, Issue , 2015, Pages 172-183

Neuroprotective effect of Valeriana wallichii rhizome extract against the neurotoxin MPTP in C57BL/6 mice

Author keywords

Antioxidants; Dopamine; MPTP; Parkinson's disease; Tyrosine hydroxylase; Valeriana wallichii D.C.

Indexed keywords

DOPAMINE; GLIAL FIBRILLARY ACIDIC PROTEIN; NEUROPROTECTIVE AGENT; PLANT EXTRACT; REACTIVE OXYGEN METABOLITE; TYROSINE 3 MONOOXYGENASE; UNCLASSIFIED DRUG; VALERIANA WALLICHII EXTRACT; ANTIOXIDANT; VALERIAN;

EID: 84946556005     PISSN: 0161813X     EISSN: 18729711     Source Type: Journal    
DOI: 10.1016/j.neuro.2015.10.012     Document Type: Article
Times cited : (28)

References (68)
  • 2
    • 80052894583 scopus 로고    scopus 로고
    • Resveratrol attenuates oxidative stress and improves behaviour in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) challenged mice
    • Anandhan A., Tamilselvam K., Vijayraja D., Ashokkumar N., Rajasankar S., Manivasagam T. Resveratrol attenuates oxidative stress and improves behaviour in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) challenged mice. Ann. Neurosci. 2010, 17:113-119.
    • (2010) Ann. Neurosci. , vol.17 , pp. 113-119
    • Anandhan, A.1    Tamilselvam, K.2    Vijayraja, D.3    Ashokkumar, N.4    Rajasankar, S.5    Manivasagam, T.6
  • 3
    • 84908142613 scopus 로고    scopus 로고
    • Protective effect of hesperidin in a model of Parkinson's disease induced by 6-hydroxydopamine in aged mice
    • (in press)
    • Antunes M.S., Goes A.T.R., Boeira S.P., Prigol M., Jesse C.R. Protective effect of hesperidin in a model of Parkinson's disease induced by 6-hydroxydopamine in aged mice. Nutrition 2014, (in press). 10.1016/j.nut.2014.03.024.
    • (2014) Nutrition
    • Antunes, M.S.1    Goes, A.T.R.2    Boeira, S.P.3    Prigol, M.4    Jesse, C.R.5
  • 4
    • 56649105351 scopus 로고    scopus 로고
    • Regulation of neuronal glutathione synthesis
    • Aoyama K., Watabe M., Nakaki T. Regulation of neuronal glutathione synthesis. J. Pharmacol. Sci. 2008, 108:227-238.
    • (2008) J. Pharmacol. Sci. , vol.108 , pp. 227-238
    • Aoyama, K.1    Watabe, M.2    Nakaki, T.3
  • 5
    • 84925645637 scopus 로고    scopus 로고
    • Glial-mediated inflammation underlying parkinsonism
    • Barcia C. Glial-mediated inflammation underlying parkinsonism. Scientifica (Cairo) 2013, 2013:357805.
    • (2013) Scientifica (Cairo) , vol.2013 , pp. 357805
    • Barcia, C.1
  • 6
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 1976, 72:248-254.
    • (1976) Anal. Biochem. , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 7
    • 0032710172 scopus 로고    scopus 로고
    • Differences in measures of exploration and fear in MHC-congenic C57BL/6J and B6-H-2K mice
    • Brown R.E., Corey S.C., Moore A.K. Differences in measures of exploration and fear in MHC-congenic C57BL/6J and B6-H-2K mice. Behav. Genet. 1999, 29:263-271.
    • (1999) Behav. Genet. , vol.29 , pp. 263-271
    • Brown, R.E.1    Corey, S.C.2    Moore, A.K.3
  • 8
    • 0036212575 scopus 로고    scopus 로고
    • Regional distribution of heme oxygenase, HSP70, and glutathione in brain: relevance for endogenous oxidant/antioxidant balance and stress tolerance
    • Calabrese V., Scapagnini G., Ravagna A., Fariello R.G., Giuffrida Stella A.M., Abraham N.G. Regional distribution of heme oxygenase, HSP70, and glutathione in brain: relevance for endogenous oxidant/antioxidant balance and stress tolerance. J. Neurosci. Res. 2002, 68:65-75.
    • (2002) J. Neurosci. Res. , vol.68 , pp. 65-75
    • Calabrese, V.1    Scapagnini, G.2    Ravagna, A.3    Fariello, R.G.4    Giuffrida Stella, A.M.5    Abraham, N.G.6
  • 9
    • 0016808562 scopus 로고
    • Purification and characterization of the flavoenzyme glutathione reductase from rat liver
    • Carlberg I., Mannervik B. Purification and characterization of the flavoenzyme glutathione reductase from rat liver. J. Biol. Chem. 1975, 250:5475-5480.
    • (1975) J. Biol. Chem. , vol.250 , pp. 5475-5480
    • Carlberg, I.1    Mannervik, B.2
  • 10
    • 74149092692 scopus 로고    scopus 로고
    • A simple protocol for assessing inter-trial and inter-examiner reliability for two noninvasive measures of limb muscle strength
    • Carlson C.G., Rutter J., Bledsoe C., Singh R., Hoff H., Bruemmer K., Sesti J., Gatti F., Berge J., McCarthy L. A simple protocol for assessing inter-trial and inter-examiner reliability for two noninvasive measures of limb muscle strength. J. Neurosci. Methods 2010, 186:226-230. 10.1016/j.jneumeth.2009.11.006.
    • (2010) J. Neurosci. Methods , vol.186 , pp. 226-230
    • Carlson, C.G.1    Rutter, J.2    Bledsoe, C.3    Singh, R.4    Hoff, H.5    Bruemmer, K.6    Sesti, J.7    Gatti, F.8    Berge, J.9    McCarthy, L.10
  • 12
    • 15744385962 scopus 로고    scopus 로고
    • Impaired memory and olfactory performance in NaSi-1 sulphate transporter deficient mice
    • Dawson P.A., Steane S.E., Markovich D. Impaired memory and olfactory performance in NaSi-1 sulphate transporter deficient mice. Behav. Brain Res. 2005, 159:15-20. 10.1016/j.bbr.2004.09.020.
    • (2005) Behav. Brain Res. , vol.159 , pp. 15-20
    • Dawson, P.A.1    Steane, S.E.2    Markovich, D.3
  • 17
    • 0037196246 scopus 로고    scopus 로고
    • A simple method to measure stride length as an index of nigrostriatal dysfunction in mice
    • Fernagut P.O., Diguet E., Labattu B., Tison F. A simple method to measure stride length as an index of nigrostriatal dysfunction in mice. J. Neurosci. Methods 2002, 113:123-130.
    • (2002) J. Neurosci. Methods , vol.113 , pp. 123-130
    • Fernagut, P.O.1    Diguet, E.2    Labattu, B.3    Tison, F.4
  • 18
    • 0020510054 scopus 로고
    • Pure population of viable neurons from rabbit dorsal root ganglia, using gradients of Percoll
    • Goldenberg S.S., De Boni U. Pure population of viable neurons from rabbit dorsal root ganglia, using gradients of Percoll. J. Neurobiol. 1983, 14:195-206.
    • (1983) J. Neurobiol. , vol.14 , pp. 195-206
    • Goldenberg, S.S.1    De Boni, U.2
  • 19
    • 0016275313 scopus 로고
    • Glutathione S-transferases. The first enzymatic step in mercapturic acid formation
    • Habig W.H., Pabst M.J., Jakoby W.B. Glutathione S-transferases. The first enzymatic step in mercapturic acid formation. J. Biol. Chem. 1974, 249:7130-7139.
    • (1974) J. Biol. Chem. , vol.249 , pp. 7130-7139
    • Habig, W.H.1    Pabst, M.J.2    Jakoby, W.B.3
  • 20
    • 34247377375 scopus 로고    scopus 로고
    • Up-regulation of Connexin43 in the glial scar following photothrombotic ischemic injury
    • Haupt C., Witte O.W., Frahm C. Up-regulation of Connexin43 in the glial scar following photothrombotic ischemic injury. Mol. Cell. Neurosci. 2007, 35:89-99.
    • (2007) Mol. Cell. Neurosci. , vol.35 , pp. 89-99
    • Haupt, C.1    Witte, O.W.2    Frahm, C.3
  • 21
    • 62549133546 scopus 로고    scopus 로고
    • Neuroinflammation in Parkinson's disease: a target for neuroprotection?
    • Hirsch E.C., Hunot S. Neuroinflammation in Parkinson's disease: a target for neuroprotection?. Lancet Neurol. 2009, 8:382-397.
    • (2009) Lancet Neurol. , vol.8 , pp. 382-397
    • Hirsch, E.C.1    Hunot, S.2
  • 22
    • 0018976162 scopus 로고
    • Pars compacta of the substantia nigra modulates motor activity but is not involved importantly in regulating food and water intake
    • Hodge G.K., Butcher L.L. Pars compacta of the substantia nigra modulates motor activity but is not involved importantly in regulating food and water intake. Naunyn. Schmiedebergs Arch. Pharmacol. 1980, 313:51-67.
    • (1980) Naunyn. Schmiedebergs Arch. Pharmacol. , vol.313 , pp. 51-67
    • Hodge, G.K.1    Butcher, L.L.2
  • 23
    • 0023263919 scopus 로고
    • Biochemical pathophysiology of Parkinson's disease
    • Hornykiewicz O., Kish S.J. Biochemical pathophysiology of Parkinson's disease. Adv. Neurol. 1987, 45:19-34.
    • (1987) Adv. Neurol. , vol.45 , pp. 19-34
    • Hornykiewicz, O.1    Kish, S.J.2
  • 24
    • 0031983381 scopus 로고    scopus 로고
    • MPTP produces differential oxidative stress and antioxidative responses in the nigrostriatal and mesolimbic dopaminergic pathways
    • Hung H.C., Lee E.H. MPTP produces differential oxidative stress and antioxidative responses in the nigrostriatal and mesolimbic dopaminergic pathways. Free Radic. Biol. Med. 1998, 24:76-84.
    • (1998) Free Radic. Biol. Med. , vol.24 , pp. 76-84
    • Hung, H.C.1    Lee, E.H.2
  • 25
    • 25844520458 scopus 로고    scopus 로고
    • Mitochondria in homeostasis of reactive oxygen species in cell, tissues, and organism
    • Jezek P., Hlavata L. Mitochondria in homeostasis of reactive oxygen species in cell, tissues, and organism. Int. J. Biochem. Cell Biol. 2005, 37:2478-2503. 10.1016/j.biocel.2005.05.013.
    • (2005) Int. J. Biochem. Cell Biol. , vol.37 , pp. 2478-2503
    • Jezek, P.1    Hlavata, L.2
  • 26
    • 78650128289 scopus 로고    scopus 로고
    • Oxidative DNA damage preventive activity and antioxidant potential of plants used in Unani system of medicine
    • Kalim M.D., Bhattacharyya D., Banerjee A., Chattopadhyay S. Oxidative DNA damage preventive activity and antioxidant potential of plants used in Unani system of medicine. BMC Complement. Altern. Med. 2010, 10:77. 10.1186/1472-6882-10-77.
    • (2010) BMC Complement. Altern. Med. , vol.10 , pp. 77
    • Kalim, M.D.1    Bhattacharyya, D.2    Banerjee, A.3    Chattopadhyay, S.4
  • 27
    • 84870174406 scopus 로고    scopus 로고
    • Radioprotective property of an aqueous extract from Valeriana wallichii
    • Katoch O., Kaushik S., Kumar M.S., Agrawala P.K., Misra K. Radioprotective property of an aqueous extract from Valeriana wallichii. J. Pharm. Bioallied Sci. 2012, 4:327-332. 10.4103/0975-7406.103272.
    • (2012) J. Pharm. Bioallied Sci. , vol.4 , pp. 327-332
    • Katoch, O.1    Kaushik, S.2    Kumar, M.S.3    Agrawala, P.K.4    Misra, K.5
  • 28
    • 84864927303 scopus 로고    scopus 로고
    • Acacetin protects dopaminergic cells against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neuroinflammation in vitro and in vivo
    • Kim H.G., Ju M.S., Ha S.K., Lee H., Lee H., Kim S.Y., Oh M.S. Acacetin protects dopaminergic cells against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neuroinflammation in vitro and in vivo. Biol. Pharm. Bull. 2012, 35(8):1287-1294.
    • (2012) Biol. Pharm. Bull. , vol.35 , Issue.8 , pp. 1287-1294
    • Kim, H.G.1    Ju, M.S.2    Ha, S.K.3    Lee, H.4    Lee, H.5    Kim, S.Y.6    Oh, M.S.7
  • 29
    • 84868152531 scopus 로고    scopus 로고
    • Recent updates in redox regulation and free radical scavenging effects by herbal products in experimental models of Parkinson's disease
    • Koppula S., Kumar H., More S.V., Lim H.W., Hong S.M., Choi D.K. Recent updates in redox regulation and free radical scavenging effects by herbal products in experimental models of Parkinson's disease. Molecules 2012, 17:11391-11420. 10.3390/molecules171011391.
    • (2012) Molecules , vol.17 , pp. 11391-11420
    • Koppula, S.1    Kumar, H.2    More, S.V.3    Lim, H.W.4    Hong, S.M.5    Choi, D.K.6
  • 30
    • 84875472017 scopus 로고    scopus 로고
    • The role of free radicals in the aging brain and Parkinson's disease: convergence and parallelism
    • Kumar H., Lim H.W., More S.V., Kim B.W., Koppula S., Kim I.S., Choi D.K. The role of free radicals in the aging brain and Parkinson's disease: convergence and parallelism. Int. J. Mol. Sci. 2012, 13:10478-10504. 10.3390/ijms130810478.
    • (2012) Int. J. Mol. Sci. , vol.13 , pp. 10478-10504
    • Kumar, H.1    Lim, H.W.2    More, S.V.3    Kim, B.W.4    Koppula, S.5    Kim, I.S.6    Choi, D.K.7
  • 31
    • 84904160762 scopus 로고    scopus 로고
    • Olfaction in three genetic and two MPTP-induced Parkinson's disease mouse models
    • Kurtenbach S., Wewering S., Hatt H., Neuhaus E.M., Lubbert H. Olfaction in three genetic and two MPTP-induced Parkinson's disease mouse models. PLOS ONE 2013, 8:e77509. 10.1371/journal.pone.0077509.
    • (2013) PLOS ONE , vol.8 , pp. e77509
    • Kurtenbach, S.1    Wewering, S.2    Hatt, H.3    Neuhaus, E.M.4    Lubbert, H.5
  • 32
    • 0025313038 scopus 로고
    • Organometal-induced increases in oxygen reactive species: the potential of 2',7'-dichlorofluorescin diacetate as an index of neurotoxic damage
    • LeBel C.P., Ali S.F., McKee M., Bondy S.C. Organometal-induced increases in oxygen reactive species: the potential of 2',7'-dichlorofluorescin diacetate as an index of neurotoxic damage. Toxicol. Appl. Pharmacol. 1990, 104:17-24.
    • (1990) Toxicol. Appl. Pharmacol. , vol.104 , pp. 17-24
    • LeBel, C.P.1    Ali, S.F.2    McKee, M.3    Bondy, S.C.4
  • 35
    • 70349681975 scopus 로고    scopus 로고
    • Glutathione - a review on its role and significance in Parkinson's disease
    • Martin H.L., Teismann P. Glutathione - a review on its role and significance in Parkinson's disease. FASEB J. 2009, 23:3263-3272.
    • (2009) FASEB J. , vol.23 , pp. 3263-3272
    • Martin, H.L.1    Teismann, P.2
  • 36
    • 0027486512 scopus 로고
    • Experimental Parkinson's disease in monkeys: effect of ergot alkaloid derivative on lipid peroxidation in different brain areas
    • Marzatico F., Café C., Taborelli M., Benzi G. Experimental Parkinson's disease in monkeys: effect of ergot alkaloid derivative on lipid peroxidation in different brain areas. Neurochem. Res. 1993, 18:1101-1106.
    • (1993) Neurochem. Res. , vol.18 , pp. 1101-1106
    • Marzatico, F.1    Café, C.2    Taborelli, M.3    Benzi, G.4
  • 37
    • 58149466868 scopus 로고    scopus 로고
    • Oxidative and inflammatory pathways in Parkinson's disease
    • Miller R.L., James-Kracke M., Sun G.Y., Sun A.Y. Oxidative and inflammatory pathways in Parkinson's disease. Neurochem. Res. 2009, 34:55-65. 10.1007/s11064-008-9656-2.
    • (2009) Neurochem. Res. , vol.34 , pp. 55-65
    • Miller, R.L.1    James-Kracke, M.2    Sun, G.Y.3    Sun, A.Y.4
  • 38
    • 0030582991 scopus 로고    scopus 로고
    • Interleukin (IL)-1 beta, IL-2, IL-4, IL-6 and transforming growth factor-alpha levels are elevated in ventricular cerebrospinal fluid in juvenile parkinsonism and Parkinson's disease
    • Mogi M., Harada M., Narabayashi H., Inagaki H., Minami M., Nagatsu T. Interleukin (IL)-1 beta, IL-2, IL-4, IL-6 and transforming growth factor-alpha levels are elevated in ventricular cerebrospinal fluid in juvenile parkinsonism and Parkinson's disease. Neurosci. Lett. 1996, 211:13-16.
    • (1996) Neurosci. Lett. , vol.211 , pp. 13-16
    • Mogi, M.1    Harada, M.2    Narabayashi, H.3    Inagaki, H.4    Minami, M.5    Nagatsu, T.6
  • 39
    • 33750503773 scopus 로고    scopus 로고
    • Enhanced neuroprotective effect by combination of bromocriptine and Hypericum perforatum extract against MPTP-induced neurotoxicity in mice
    • Mohanasundari M., Srinivasan M.S., Sethupathy S., Sabesan M. Enhanced neuroprotective effect by combination of bromocriptine and Hypericum perforatum extract against MPTP-induced neurotoxicity in mice. J. Neurol. Sci. 2006, 249:140-144. 10.1016/j.jns.2006.06.018.
    • (2006) J. Neurol. Sci. , vol.249 , pp. 140-144
    • Mohanasundari, M.1    Srinivasan, M.S.2    Sethupathy, S.3    Sabesan, M.4
  • 40
    • 70449527787 scopus 로고    scopus 로고
    • Neuroprotective effect of ghrelin in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease by blocking microglial activation
    • Moon M., Kim H.G., Hwang L., Seo J.H., Kim S., Hwang S., Lee D., Chung H., Oh M.S., Lee K.T., Park S. Neuroprotective effect of ghrelin in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease by blocking microglial activation. Neurotox. Res. 2009, 15:332-347.
    • (2009) Neurotox. Res. , vol.15 , pp. 332-347
    • Moon, M.1    Kim, H.G.2    Hwang, L.3    Seo, J.H.4    Kim, S.5    Hwang, S.6    Lee, D.7    Chung, H.8    Oh, M.S.9    Lee, K.T.10    Park, S.11
  • 41
    • 84885350806 scopus 로고    scopus 로고
    • Advances in neuroprotective ingredients of medicinal herbs by using cellular and animal models of Parkinson's disease
    • More S.V., Kumar H., Kang S.M., Song S.Y., Lee K., Choi D.K. Advances in neuroprotective ingredients of medicinal herbs by using cellular and animal models of Parkinson's disease. Evid. Based Complement. Alternat. Med. 2013, 2013:957875. 10.1155/2013/957875.
    • (2013) Evid. Based Complement. Alternat. Med. , vol.2013 , pp. 957875
    • More, S.V.1    Kumar, H.2    Kang, S.M.3    Song, S.Y.4    Lee, K.5    Choi, D.K.6
  • 42
    • 0034525420 scopus 로고    scopus 로고
    • Changes in cytokines and neurotrophins in Parkinson's disease
    • Nagatsu T., Mogi M., Ichinose H., Togari A. Changes in cytokines and neurotrophins in Parkinson's disease. J. Neural Transm. 2000, 277-290.
    • (2000) J. Neural Transm. , pp. 277-290
    • Nagatsu, T.1    Mogi, M.2    Ichinose, H.3    Togari, A.4
  • 43
    • 0018384650 scopus 로고
    • Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction
    • Ohkawa H., Ohishi N., Yagi K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal. Biochem. 1979, 95:351-358.
    • (1979) Anal. Biochem. , vol.95 , pp. 351-358
    • Ohkawa, H.1    Ohishi, N.2    Yagi, K.3
  • 44
    • 69949102761 scopus 로고    scopus 로고
    • Withania somnifera root extract improves catecholamines and physiological abnormalities seen in a Parkinson's disease model mouse
    • RajaSankar S., Manivasagam T., Sankar V., Prakash S., Muthusamy R., Krishnamurti A., Surendran S. Withania somnifera root extract improves catecholamines and physiological abnormalities seen in a Parkinson's disease model mouse. J. Ethnopharmacol. 2009, 125:369-373. 10.1016/j.jep.2009.08.003.
    • (2009) J. Ethnopharmacol. , vol.125 , pp. 369-373
    • RajaSankar, S.1    Manivasagam, T.2    Sankar, V.3    Prakash, S.4    Muthusamy, R.5    Krishnamurti, A.6    Surendran, S.7
  • 45
    • 35748940310 scopus 로고    scopus 로고
    • Effect of chlorophyll and aqueous extracts of Bacopa monniera and Valeriana wallichii on ischaemia and reperfusion-induced cerebral injury in mice
    • Rehni A.K., Pantlya H.S., Shri R., Singh M. Effect of chlorophyll and aqueous extracts of Bacopa monniera and Valeriana wallichii on ischaemia and reperfusion-induced cerebral injury in mice. Indian J. Exp. Biol. 2007, 45:764-769.
    • (2007) Indian J. Exp. Biol. , vol.45 , pp. 764-769
    • Rehni, A.K.1    Pantlya, H.S.2    Shri, R.3    Singh, M.4
  • 46
    • 0034846276 scopus 로고    scopus 로고
    • Astroglial and microglial reaction after a partial nigrostriatal degeneration induced by the striatal injection of different doses of 6-hydroxydopamine
    • Rodrigues R.W., Gomide V.C., Chadi G. Astroglial and microglial reaction after a partial nigrostriatal degeneration induced by the striatal injection of different doses of 6-hydroxydopamine. Int. J. Neurosci. 2001, 109:91-126.
    • (2001) Int. J. Neurosci. , vol.109 , pp. 91-126
    • Rodrigues, R.W.1    Gomide, V.C.2    Chadi, G.3
  • 47
    • 0027269914 scopus 로고
    • Increased striatal lipid peroxidation after intracerebroventricular MPP + administration to mice
    • Rojas P., Rios C. Increased striatal lipid peroxidation after intracerebroventricular MPP + administration to mice. Pharmacol. Toxicol. 1993, 72:364-368.
    • (1993) Pharmacol. Toxicol. , vol.72 , pp. 364-368
    • Rojas, P.1    Rios, C.2
  • 50
    • 84928614843 scopus 로고    scopus 로고
    • Valeriana wallichii: a phyto-pharmacological review
    • Sangeeta P.S., Mathela C.S., Chopra K. Valeriana wallichii: a phyto-pharmacological review. J. Pharm. Res. 2010, 3:2337-2339.
    • (2010) J. Pharm. Res. , vol.3 , pp. 2337-2339
    • Sangeeta, P.S.1    Mathela, C.S.2    Chopra, K.3
  • 51
    • 38049153249 scopus 로고    scopus 로고
    • The neuroprotective effect of Withania somnifera root extract in MPTP-intoxicated mice: an analysis of behavioral and biochemical variables
    • Sankar S.R., Manivasagam T., Krishnamurti A., Ramanathan M. The neuroprotective effect of Withania somnifera root extract in MPTP-intoxicated mice: an analysis of behavioral and biochemical variables. Cell. Mol. Biol. Lett. 2007, 12:473-481. 10.2478/s11658-007-0015-0.
    • (2007) Cell. Mol. Biol. Lett. , vol.12 , pp. 473-481
    • Sankar, S.R.1    Manivasagam, T.2    Krishnamurti, A.3    Ramanathan, M.4
  • 52
    • 0035214256 scopus 로고    scopus 로고
    • Neurochemical findings in the MPTP model of Parkinson's disease
    • Schmidt N., Ferger B. Neurochemical findings in the MPTP model of Parkinson's disease. J. Neural Transm. 2001, 108:1263-1282.
    • (2001) J. Neural Transm. , vol.108 , pp. 1263-1282
    • Schmidt, N.1    Ferger, B.2
  • 53
    • 0033749345 scopus 로고    scopus 로고
    • MPTP susceptibility in the mouse: behavioral, neurochemical, and histological analysis of gender and strain differences
    • Sedelis M., Hofele K., Auburger G.W., Morgan S., Huston J.P., Schwarting R.K. MPTP susceptibility in the mouse: behavioral, neurochemical, and histological analysis of gender and strain differences. Behav. Genet. 2000, 30:171-182.
    • (2000) Behav. Genet. , vol.30 , pp. 171-182
    • Sedelis, M.1    Hofele, K.2    Auburger, G.W.3    Morgan, S.4    Huston, J.P.5    Schwarting, R.K.6
  • 54
    • 84867578575 scopus 로고    scopus 로고
    • Alcoholic extract of Bacopa monniera Linn. protects against 6-hydroxydopamine-induced changes in behavioral and biochemical aspects: a pilot study
    • Shobana C., Kumar R.R., Sumathi T. Alcoholic extract of Bacopa monniera Linn. protects against 6-hydroxydopamine-induced changes in behavioral and biochemical aspects: a pilot study. Cell. Mol. Neurobiol. 2012, 32:1099-1112. 10.1007/s10571-012-9833-3.
    • (2012) Cell. Mol. Neurobiol. , vol.32 , pp. 1099-1112
    • Shobana, C.1    Kumar, R.R.2    Sumathi, T.3
  • 55
    • 84884901192 scopus 로고    scopus 로고
    • Glutathione metabolism and Parkinson's disease
    • Smeyne M., Smeyne R.J. Glutathione metabolism and Parkinson's disease. Free Radic. Biol. Med. 2013, 62:13-25.
    • (2013) Free Radic. Biol. Med. , vol.62 , pp. 13-25
    • Smeyne, M.1    Smeyne, R.J.2
  • 56
    • 0031036391 scopus 로고    scopus 로고
    • Evidence for generation of oxidative stress in brain by MPTP: in vitro and in vivo studies in mice
    • Sriram K., Pai K.S., Boyd M.R., Ravindranath V. Evidence for generation of oxidative stress in brain by MPTP: in vitro and in vivo studies in mice. Brain Res. 1997, 749:44-52.
    • (1997) Brain Res. , vol.749 , pp. 44-52
    • Sriram, K.1    Pai, K.S.2    Boyd, M.R.3    Ravindranath, V.4
  • 57
    • 85019298507 scopus 로고    scopus 로고
    • In vitro neuroprotective effect of Valeriana wallichii extract against neurotoxin and endoplasmic reticulum stress induced cell death in SH-SY5Y cells
    • Subhashree S., Kumaravel M., Syam Praveen Kumar J., Sudha Rani S. In vitro neuroprotective effect of Valeriana wallichii extract against neurotoxin and endoplasmic reticulum stress induced cell death in SH-SY5Y cells. Am. J. Phytomed. Clin. Ther. 2014, 2:509-523.
    • (2014) Am. J. Phytomed. Clin. Ther. , vol.2 , pp. 509-523
    • Subhashree, S.1    Kumaravel, M.2    Syam Praveen Kumar, J.3    Sudha Rani, S.4
  • 60
    • 0026353406 scopus 로고
    • Rescue of dying neurons: a new action for deprenyl in MPTP parkinsonism
    • Tatton W.G., Greenwood C.E. Rescue of dying neurons: a new action for deprenyl in MPTP parkinsonism. J. Neurosci. Res. 1991, 30:666-672.
    • (1991) J. Neurosci. Res. , vol.30 , pp. 666-672
    • Tatton, W.G.1    Greenwood, C.E.2
  • 61
    • 0036447089 scopus 로고    scopus 로고
    • Detection of behavioral impairments correlated to neurochemical deficits in mice treated with moderate doses of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
    • Tillerson J.L., Caudle W.M., Reveron M.E., Miller G.W. Detection of behavioral impairments correlated to neurochemical deficits in mice treated with moderate doses of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Exp. Neurol. 2002, 178:80-90.
    • (2002) Exp. Neurol. , vol.178 , pp. 80-90
    • Tillerson, J.L.1    Caudle, W.M.2    Reveron, M.E.3    Miller, G.W.4
  • 62
    • 34547435817 scopus 로고    scopus 로고
    • Neuroinflammation and regulation of glial glutamate uptake in neurological disorders
    • Tilleux S., Hermans E. Neuroinflammation and regulation of glial glutamate uptake in neurological disorders. J. Neurosci. Res. 2007, 85:2059-2070.
    • (2007) J. Neurosci. Res. , vol.85 , pp. 2059-2070
    • Tilleux, S.1    Hermans, E.2
  • 63
    • 0009482260 scopus 로고
    • Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications
    • Towbin H., Staehelin T., Gordon J. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc. Natl. Acad. Sci. U. S. A. 1979, 76:4350-4354.
    • (1979) Proc. Natl. Acad. Sci. U. S. A. , vol.76 , pp. 4350-4354
    • Towbin, H.1    Staehelin, T.2    Gordon, J.3
  • 64
    • 84864258203 scopus 로고    scopus 로고
    • Isolation, structural elucidation, and neuroprotective effects of iridoids from Valeriana jatamansi
    • Xu J., Li Y., Guo Y., Guo P., Yamakuni T., Ohizumi Y. Isolation, structural elucidation, and neuroprotective effects of iridoids from Valeriana jatamansi. Biosci. Biotechnol. Biochem. 2012, 76:1401-1403.
    • (2012) Biosci. Biotechnol. Biochem. , vol.76 , pp. 1401-1403
    • Xu, J.1    Li, Y.2    Guo, Y.3    Guo, P.4    Yamakuni, T.5    Ohizumi, Y.6
  • 65
    • 84877070971 scopus 로고    scopus 로고
    • Mucuna pruriens seed extract reduces oxidative stress in nigrostriatal tissue and improves neurobehavioral activity in paraquat-induced Parkinsonian mouse model
    • Yadav S.K., Prakash J., Chouhan S., Singh S.P. Mucuna pruriens seed extract reduces oxidative stress in nigrostriatal tissue and improves neurobehavioral activity in paraquat-induced Parkinsonian mouse model. Neurochem. Int. 2013, 62:1039-1047. 10.1016/j.neuint.2013.03.015.
    • (2013) Neurochem. Int. , vol.62 , pp. 1039-1047
    • Yadav, S.K.1    Prakash, J.2    Chouhan, S.3    Singh, S.P.4
  • 66
    • 67749118329 scopus 로고    scopus 로고
    • Simple behavioral assessment of mouse olfaction
    • Chapter 8, Unit 8.24
    • Yang M., Crawley J.N. Simple behavioral assessment of mouse olfaction. Curr. Protoc. Neurosci. 2009, Chapter 8, Unit 8.24. 10.1002/0471142301.ns0824s48.
    • (2009) Curr. Protoc. Neurosci.
    • Yang, M.1    Crawley, J.N.2
  • 67
    • 33947323582 scopus 로고    scopus 로고
    • TNF-alpha knockout and minocycline treatment attenuates blood-brain barrier leakage in MPTP-treated mice
    • Zhao C., Ling Z., Newman M.B., Bhatia A., Carvey P.M. TNF-alpha knockout and minocycline treatment attenuates blood-brain barrier leakage in MPTP-treated mice. Neurobiol. Dis. 2007, 26:36-46.
    • (2007) Neurobiol. Dis. , vol.26 , pp. 36-46
    • Zhao, C.1    Ling, Z.2    Newman, M.B.3    Bhatia, A.4    Carvey, P.M.5
  • 68
    • 84885388816 scopus 로고    scopus 로고
    • The impact of reactive oxygen species and genetic mitochondrial mutations in Parkinson's disease
    • Zuo L., Motherwell M.S. The impact of reactive oxygen species and genetic mitochondrial mutations in Parkinson's disease. Gene 2013, 532:18-23. 10.1016/j.gene.2013.07.085.
    • (2013) Gene , vol.532 , pp. 18-23
    • Zuo, L.1    Motherwell, M.S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.