Targeting the reconsolidation of extinction memories: A novel potential strategy to treat anxiety disorders

Molecular Psychiatry

Volumn 20, Issue 11, 2015, Pages 1264-1265

  Rosas Vidal, L E ^a   Rodriguez Romaguera, J ^a   Do Monte, F H ^a   Andero, R ^b  

^a UNIVERSITY OF PUERTO RICO SCHOOL OF MEDICINE   (Puerto Rico)

^b MCLEAN HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ABRINEURIN; BRAIN DERIVED NEUROTROPHIC FACTOR; BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR;

ANXIETY; ANXIETY DISORDER; AVOIDANCE BEHAVIOR; BRAIN REGION; DORSAL HIPPOCAMPUS; DRUG SAFETY; FEAR; FOOTSHOCK; GENE EXPRESSION; HUMAN; LONG TERM MEMORY; MEMORY CONSOLIDATION; NEUROLOGIC DISEASE; NONHUMAN; NOTE; PREFRONTAL CORTEX; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; ANIMAL; MEMORY; PHYSIOLOGY; REINFORCEMENT;

ANIMALS; BRAIN-DERIVED NEUROTROPHIC FACTOR; EXTINCTION, PSYCHOLOGICAL; FEAR; MEMORY;

EID: 84946495677     PISSN: 13594184     EISSN: 14765578     Source Type: Journal    
DOI: 10.1038/mp.2015.136     Document Type: Note

References (10)

1. Vervliet B, Craske MG, Hermans D. Fear extinction and relapse: state of the art. Annu Rev Clin Psychol 2013; 9: 215-248.
2. Schwabe L, Nader K, Pruessner JC. Reconsolidation of human memory: brain mechanisms and clinical relevance. Biol Psychiatry 2014; 76: 274-280.
3. Eisenberg M, Dudai Y. Reconsolidation of fresh, remote, and extinguished fear memory in Medaka: old fears don't die. Eur J Neurosci 2004; 20: 3397-3403.
4. Milekic MH, Pollonini G, Alberini CM. Temporal requirement of C/EBPbeta in the amygdala following reactivation but not acquisition of inhibitory avoidance. Learn Mem 2007; 14: 504-511.
5. Radiske A, Rossato JI, Kohler CA, Gonzalez MC, Medina JH, Cammarota M. Requirement for BDNF in the reconsolidation of fear extinction. J Neurosci 2015; 35: 6570-6574.
6. Andero R, Ressler KJ. Fear extinction and BDNF: translating animal models of PTSD to the clinic. Genes Brain Behav 2012; 11: 503-512.
7. Giachero M, Bustos SG, Calfa G, Molina VA. A BDNF sensitive mechanism is involved in the fear memory resulting from the interaction between stress and the retrieval of an established trace. Learn Mem 2013; 20: 245-255.
8. Rosas-Vidal LE, Do-Monte FH, Sotres-Bayon F, Quirk GJ. Hippocampal-prefrontal BDNF and memory for fear extinction. Neuropsychopharmacology 2014; 39: 2161-2169.
9. Wu D. Neuroprotection in experimental stroke with targeted neurotrophins. NeuroRx 2005; 2: 120-128.
10. Meeusen R. Exercise, nutrition and the brain. Sports Med 2014; 44: S47-S56.