-
1
-
-
84877753528
-
Current and future therapies for hepatitis C virus infection
-
COI: 1:CAS:528:DC%2BC3sXnsl2gs78%3D, PID: 23675659
-
Liang TJ, Ghany MG (2013) Current and future therapies for hepatitis C virus infection. N Engl J Med 368:1907–1917. doi:10.1056/NEJMra1213651
-
(2013)
N Engl J Med
, vol.368
, pp. 1907-1917
-
-
Liang, T.J.1
Ghany, M.G.2
-
2
-
-
84896520682
-
Antiviral therapy of hepatitis C in 2014: do we need resistance testing?
-
COI: 1:CAS:528:DC%2BC2cXmsVKrtbo%3D, PID: 24583028
-
Schneider MD, Sarrazin C (2014) Antiviral therapy of hepatitis C in 2014: do we need resistance testing? Antiviral Res 105:64–71. doi:10.1016/j.antiviral.2014.02.011
-
(2014)
Antiviral Res
, vol.105
, pp. 64-71
-
-
Schneider, M.D.1
Sarrazin, C.2
-
3
-
-
84907302681
-
Treatment of HCV infection with the novel NS3/4A protease inhibitors
-
De Luca A, Bianco C, Rossetti B (2014) Treatment of HCV infection with the novel NS3/4A protease inhibitors. Curr Opin Pharmacol 18C:9–17. doi:10.1016/j.coph.2014.07.016
-
(2014)
Curr Opin Pharmacol
, vol.18C
, pp. 9-17
-
-
De Luca, A.1
Bianco, C.2
Rossetti, B.3
-
4
-
-
84885952071
-
Impact of host and virus genome variability on HCV replication and response to interferon
-
COI: 1:CAS:528:DC%2BC3sXhtVOis77M, PID: 23835049
-
Schweitzer CJ, Liang TJ (2013) Impact of host and virus genome variability on HCV replication and response to interferon. Curr Opin Virol 3:501–507. doi:10.1016/j.coviro.2013.06.005
-
(2013)
Curr Opin Virol
, vol.3
, pp. 501-507
-
-
Schweitzer, C.J.1
Liang, T.J.2
-
5
-
-
51749123143
-
Natural prevalence of hepatitis C virus variants with decreased sensitivity to NS3.4A protease inhibitors in treatment-naive subjects
-
COI: 1:CAS:528:DC%2BD1cXhtFygs7rE, PID: 18637752
-
Bartels DJ, Zhou Y, Zhang EZ et al (2008) Natural prevalence of hepatitis C virus variants with decreased sensitivity to NS3.4A protease inhibitors in treatment-naive subjects. J Infect Dis 198:800–807. doi:10.1086/591141
-
(2008)
J Infect Dis
, vol.198
, pp. 800-807
-
-
Bartels, D.J.1
Zhou, Y.2
Zhang, E.Z.3
-
6
-
-
84858690642
-
Naturally occurring hepatitis C virus (HCV) NS3/4A protease inhibitor resistance-related mutations in HCV genotype 1-infected subjects in Italy
-
COI: 1:CAS:528:DC%2BC38Xkt1ersr8%3D, PID: 22258932
-
Vicenti I, Rosi A, Saladini F et al (2012) Naturally occurring hepatitis C virus (HCV) NS3/4A protease inhibitor resistance-related mutations in HCV genotype 1-infected subjects in Italy. J Antimicrob Chemother 67:984–987. doi:10.1093/jac/dkr581
-
(2012)
J Antimicrob Chemother
, vol.67
, pp. 984-987
-
-
Vicenti, I.1
Rosi, A.2
Saladini, F.3
-
7
-
-
34247594930
-
Dynamic hepatitis C virus genotypic and phenotypic changes in patients treated with the protease inhibitor telaprevir
-
COI: 1:CAS:528:DC%2BD2sXmsVyms7s%3D, PID: 17484874
-
Sarrazin C, Kieffer TL, Bartels D et al (2007) Dynamic hepatitis C virus genotypic and phenotypic changes in patients treated with the protease inhibitor telaprevir. Gastroenterology 132:1767–1777. doi:10.1053/j.gastro.2007.02.037
-
(2007)
Gastroenterology
, vol.132
, pp. 1767-1777
-
-
Sarrazin, C.1
Kieffer, T.L.2
Bartels, D.3
-
8
-
-
73149113353
-
Characterization of resistance to the protease inhibitor boceprevir in hepatitis C virus-infected patients
-
COI: 1:CAS:528:DC%2BD1MXhs1SjurrJ, PID: 19787809
-
Susser S, Welsch C, Wang Y et al (2009) Characterization of resistance to the protease inhibitor boceprevir in hepatitis C virus-infected patients. Hepatology 50:1709–1718. doi:10.1002/hep.23192
-
(2009)
Hepatology
, vol.50
, pp. 1709-1718
-
-
Susser, S.1
Welsch, C.2
Wang, Y.3
-
9
-
-
84922981045
-
Relationship between the early Boceprevir-S isomer plasma concentrations and the onset of breakthrough during HCV genotype 1 triple therapy
-
PID: 25658567
-
Boglione L, De Nicolò A, Cardellino CS et al (2015) Relationship between the early Boceprevir-S isomer plasma concentrations and the onset of breakthrough during HCV genotype 1 triple therapy. Clin Microbiol Infect 21(205):e1–e3. doi:10.1016/j.cmi.2014.07.009
-
(2015)
Clin Microbiol Infect
, vol.21
, Issue.205
, pp. e1-e3
-
-
Boglione, L.1
De Nicolò, A.2
Cardellino, C.S.3
-
10
-
-
84878116773
-
Implications of baseline polymorphisms for potential resistance to NS3 protease inhibitors in Hepatitis C virus genotypes 1a, 2b and 3a
-
COI: 1:CAS:528:DC%2BC3sXptV2gsrg%3D, PID: 23648709
-
Palanisamy N, Danielsson A, Kokkula C et al (2013) Implications of baseline polymorphisms for potential resistance to NS3 protease inhibitors in Hepatitis C virus genotypes 1a, 2b and 3a. Antiviral Res 99:12–17. doi:10.1016/j.antiviral.2013.04.018
-
(2013)
Antiviral Res
, vol.99
, pp. 12-17
-
-
Palanisamy, N.1
Danielsson, A.2
Kokkula, C.3
-
11
-
-
84906053496
-
Simeprevir with pegylated interferon alfa 2a plus ribavirin in treatment-naive patients with chronic hepatitis C virus genotype 1 infection (QUEST-1): a phase 3, randomised, double-blind, placebo-controlled trial
-
COI: 1:CAS:528:DC%2BC2cXpslCnuro%3D, PID: 24907225
-
Jacobson IM, Dore GJ, Foster GR et al (2014) Simeprevir with pegylated interferon alfa 2a plus ribavirin in treatment-naive patients with chronic hepatitis C virus genotype 1 infection (QUEST-1): a phase 3, randomised, double-blind, placebo-controlled trial. Lancet 384:403–413. doi:10.1016/S0140-6736(14)60494-3
-
(2014)
Lancet
, vol.384
, pp. 403-413
-
-
Jacobson, I.M.1
Dore, G.J.2
Foster, G.R.3
-
12
-
-
84906059095
-
Simeprevir with pegylated interferon alfa 2a or 2b plus ribavirin in treatment-naive patients with chronic hepatitis C virus genotype 1 infection (QUEST-2): a randomised, double-blind, placebo-controlled phase 3 trial
-
COI: 1:CAS:528:DC%2BC2cXpslCnur0%3D, PID: 24907224
-
Manns M, Marcellin P, Poordad F et al (2014) Simeprevir with pegylated interferon alfa 2a or 2b plus ribavirin in treatment-naive patients with chronic hepatitis C virus genotype 1 infection (QUEST-2): a randomised, double-blind, placebo-controlled phase 3 trial. Lancet 384:414–426. doi:10.1016/S0140-6736(14)60538-9
-
(2014)
Lancet
, vol.384
, pp. 414-426
-
-
Manns, M.1
Marcellin, P.2
Poordad, F.3
-
13
-
-
77951210464
-
In vitro resistance profile of the hepatitis C virus NS3/4A protease inhibitor TMC435
-
COI: 1:CAS:528:DC%2BC3cXmtFelsrc%3D, PID: 20176898
-
Lenz O, Verbinnen T, Lin TI et al (2010) In vitro resistance profile of the hepatitis C virus NS3/4A protease inhibitor TMC435. Antimicrob Agents Chemother 54:1878–1887. doi:10.1128/AAC.01452-09
-
(2010)
Antimicrob Agents Chemother
, vol.54
, pp. 1878-1887
-
-
Lenz, O.1
Verbinnen, T.2
Lin, T.I.3
-
14
-
-
80055075318
-
NS3 protease polymorphism and natural resistance to protease inhibitors in French patients infected with HCV genotypes 1-5
-
COI: 1:CAS:528:DC%2BC3MXhs1ejtLbM
-
Vallet S, Viron F, Henquell C et al (2011) NS3 protease polymorphism and natural resistance to protease inhibitors in French patients infected with HCV genotypes 1-5. Antiviral Ther 16:1093–1102. doi:10.3851/IMP1900
-
(2011)
Antiviral Ther
, vol.16
, pp. 1093-1102
-
-
Vallet, S.1
Viron, F.2
Henquell, C.3
-
15
-
-
84924322661
-
Prevalence of HCV NS3 pre-treatment resistance associated amino acid variants within a Scottish cohort
-
COI: 1:CAS:528:DC%2BC2MXis1Sjtb8%3D, PID: 25766988
-
Shepherd SJ, Abdelrahman T, MacLean AR et al (2015) Prevalence of HCV NS3 pre-treatment resistance associated amino acid variants within a Scottish cohort. J Clin Virol 65:50–53. doi:10.1016/j.jcv.2015.02.005
-
(2015)
J Clin Virol
, vol.65
, pp. 50-53
-
-
Shepherd, S.J.1
Abdelrahman, T.2
MacLean, A.R.3
-
16
-
-
84973573737
-
Baseline prevalence and emergence of protease inhibitor resistance mutations following treatment in chronic HCV genotype 1-infected individuals
-
Nguyen LT, Gray E, Dean J, Carr M, Connell J, De Gascun C, Nguyen LA, O’Leary A, Bergin C, Hall WNS (2015) Baseline prevalence and emergence of protease inhibitor resistance mutations following treatment in chronic HCV genotype 1-infected individuals. Antiviral Ther 107:3851. doi:10.3851/IMP2964
-
(2015)
Antiviral Ther
, vol.107
, pp. 3851
-
-
Nguyen, L.T.1
Gray, E.2
Dean, J.3
Carr, M.4
Connell, J.5
De Gascun, C.6
Nguyen, L.A.7
O’Leary, A.8
Bergin, C.9
Hall, W.N.S.10
-
17
-
-
84925446450
-
Simeprevir with peginterferon/ribavirin for treatment of chronic hepatitis C virus genotype 1 infection: pooled safety analysis from Phase IIb and III studies
-
PID: 25363449
-
Manns MP, Fried MW, Zeuzem S et al (2014) Simeprevir with peginterferon/ribavirin for treatment of chronic hepatitis C virus genotype 1 infection: pooled safety analysis from Phase IIb and III studies. J Viral Hepat 22:366–375. doi:10.1111/jvh.12346
-
(2014)
J Viral Hepat
, vol.22
, pp. 366-375
-
-
Manns, M.P.1
Fried, M.W.2
Zeuzem, S.3
-
18
-
-
78649644443
-
Susceptibility of treatment-naive hepatitis C virus (HCV) clinical isolates to HCV protease inhibitors
-
COI: 1:CAS:528:DC%2BC3cXhsF2msr7J, PID: 20855726
-
Bae A, Sun SC, Qi X et al (2010) Susceptibility of treatment-naive hepatitis C virus (HCV) clinical isolates to HCV protease inhibitors. Antimicrob Agents Chemother 54:5288–5297. doi:10.1128/AAC.00777-10
-
(2010)
Antimicrob Agents Chemother
, vol.54
, pp. 5288-5297
-
-
Bae, A.1
Sun, S.C.2
Qi, X.3
-
19
-
-
79960937707
-
Evidence for separation of HCV subtype 1a into two distinct clades
-
COI: 1:STN:280:DC%2BC3MjhsFCntQ%3D%3D, PID: 20565573
-
Pickett BE, Striker R, Lefkowitz EJ (2011) Evidence for separation of HCV subtype 1a into two distinct clades. J Viral Hepat 18:608–618. doi:10.1111/j.1365-2893.2010.01342.x
-
(2011)
J Viral Hepat
, vol.18
, pp. 608-618
-
-
Pickett, B.E.1
Striker, R.2
Lefkowitz, E.J.3
-
20
-
-
84922318694
-
Prevalence of the hepatitis C virus NS3 polymorphism Q80K in genotype 1 patients in the European region
-
COI: 1:CAS:528:DC%2BC2MXhtF2ks7o%3D, PID: 25614456
-
Sarrazin C, Lathouwers E, Peeters M et al (2015) Prevalence of the hepatitis C virus NS3 polymorphism Q80K in genotype 1 patients in the European region. Antiviral Res 116:10–16. doi:10.1016/j.antiviral.2015.01.003
-
(2015)
Antiviral Res
, vol.116
, pp. 10-16
-
-
Sarrazin, C.1
Lathouwers, E.2
Peeters, M.3
-
21
-
-
84911409020
-
Simeprevir plus sofosbuvir, with or without ribavirin, to treat chronic infection with hepatitis C virus genotype 1 in non-responders to pegylated interferon and ribavirin and treatment-naive patients: the COSMOS randomised study
-
COI: 1:CAS:528:DC%2BC2cXhtlSru7vM, PID: 25078309
-
Lawitz E, Sulkowski MS, Ghalib R et al (2014) Simeprevir plus sofosbuvir, with or without ribavirin, to treat chronic infection with hepatitis C virus genotype 1 in non-responders to pegylated interferon and ribavirin and treatment-naive patients: the COSMOS randomised study. Lancet 384:1756–1765. doi:10.1016/S0140-6736(14)61036-9
-
(2014)
Lancet
, vol.384
, pp. 1756-1765
-
-
Lawitz, E.1
Sulkowski, M.S.2
Ghalib, R.3
-
22
-
-
84892529894
-
EASL Clinical Practice Guidelines: management of hepatitis C virus infection
-
EASL (European Association for Study of Liver) (2014) EASL Clinical Practice Guidelines: management of hepatitis C virus infection. J Hepatol 60:392–420. doi:10.1016/j.jhep.2013.11.003
-
(2014)
J Hepatol
, vol.60
, pp. 392-420
-
-
Easl (European Association for Study of Liver)1
-
23
-
-
84946510820
-
Olysio (Simeprevir). Highlights of prescribing information
-
LP, Titusville
-
Janssen (2013) Olysio (Simeprevir). Highlights of prescribing information. Janssen Product, LP, Titusville
-
(2013)
Janssen Product
-
-
-
24
-
-
84893472499
-
Baseline hepatitis C virus (HCV) NS3 polymorphisms and their impact on treatment response in clinical studies of the HCV NS3 protease inhibitor faldaprevir
-
PID: 24217701
-
Berger KL, Triki I, Cartier M et al (2014) Baseline hepatitis C virus (HCV) NS3 polymorphisms and their impact on treatment response in clinical studies of the HCV NS3 protease inhibitor faldaprevir. Antimicrob Agents Chemother 58:698–705. doi:10.1128/AAC.01976-13
-
(2014)
Antimicrob Agents Chemother
, vol.58
, pp. 698-705
-
-
Berger, K.L.1
Triki, I.2
Cartier, M.3
-
26
-
-
67651148377
-
Detection of hepatitis C mutants with natural resistance to NS3/4A protease inhibitors in HIV-HCV coinfected individuals treated with antiretroviral therapy
-
Morsica G, Bagaglio S, Uberti-Foppa C, LA Galli L (2009) Detection of hepatitis C mutants with natural resistance to NS3/4A protease inhibitors in HIV-HCV coinfected individuals treated with antiretroviral therapy. J Acquir Immune Defic Syndr 51(106–10):104–110
-
(2009)
J Acquir Immune Defic Syndr
, vol.51
, Issue.106-10
, pp. 104-110
-
-
Morsica, G.1
Bagaglio, S.2
Uberti-Foppa, C.3
LA Galli, L.4
-
27
-
-
84924103954
-
Deconvoluting the composition of low-frequency hepatitis C viral quasispecies: comparison of genotypes and NS3 resistance-associated variants between HCV/HIV coinfected hemophiliacs and HCV monoinfected patients in Japan
-
PID: 25748426
-
Ogishi M, Yotsuyanagi H, Tsutsumi T et al (2015) Deconvoluting the composition of low-frequency hepatitis C viral quasispecies: comparison of genotypes and NS3 resistance-associated variants between HCV/HIV coinfected hemophiliacs and HCV monoinfected patients in Japan. PLoS ONE 10:e0119145. doi:10.1371/journal.pone.0119145
-
(2015)
PLoS ONE
, vol.10
, pp. e0119145
-
-
Ogishi, M.1
Yotsuyanagi, H.2
Tsutsumi, T.3
-
28
-
-
84937074015
-
Molecular characterization of hepatitis C virus for determination of subtypes and detection of resistance mutations to protease inhibitors in a group of intravenous drug users co-infected with HIV
-
Silva T, Cortes Martins H, Coutinho R, Leitao E, Silva RPE (2015) Molecular characterization of hepatitis C virus for determination of subtypes and detection of resistance mutations to protease inhibitors in a group of intravenous drug users co-infected with HIV. J Med Virol. doi:10.1002/jmv.24213
-
(2015)
J Med Virol
-
-
Silva, T.1
Cortes, M.H.2
Coutinho, R.3
Leitao, E.4
Silva, R.P.E.5
-
29
-
-
84942648838
-
Appearance of NS3 Q80K mutation in HCV genotype 1a mono- or HIV/HCV co-infected patients in a Berlin laboratory
-
PID: 25397486
-
Ehret R, Neifer S, Walter H et al (2014) Appearance of NS3 Q80K mutation in HCV genotype 1a mono- or HIV/HCV co-infected patients in a Berlin laboratory. J Int AIDS Soc 17:19741
-
(2014)
J Int AIDS Soc
, vol.17
, pp. 19741
-
-
Ehret, R.1
Neifer, S.2
Walter, H.3
-
30
-
-
52249086710
-
Mutation rate in hepatitis C virus NS3 protease is not influenced by HIV-1 protease inhibitor therapy
-
Halfon P, Bourliere MKH et al (2008) Mutation rate in hepatitis C virus NS3 protease is not influenced by HIV-1 protease inhibitor therapy. AIDS 22(1683–1):1683–1698
-
(2008)
AIDS
, vol.22
, Issue.1683-1
, pp. 1683-1698
-
-
Halfon, P.1
Bourliere, M.K.H.2
-
31
-
-
80051599715
-
Hepatitis C virus (HCV) protease variability and anti-HCV protease inhibitor resistance in HIV/HCV-coinfected patients
-
COI: 1:CAS:528:DC%2BC3MXht1eqsLzI, PID: 21410862
-
Trimoulet P, Belzunce C, Faure M et al (2011) Hepatitis C virus (HCV) protease variability and anti-HCV protease inhibitor resistance in HIV/HCV-coinfected patients. HIV Med 12:506–509. doi:10.1111/j.1468-1293.2011.00913.x
-
(2011)
HIV Med
, vol.12
, pp. 506-509
-
-
Trimoulet, P.1
Belzunce, C.2
Faure, M.3
-
32
-
-
84901318422
-
Resistance to hepatitis C virus protease inhibitors
-
COI: 1:CAS:528:DC%2BC2cXhslGjsbbF, PID: 24852142
-
Kieffer TL, George S (2014) Resistance to hepatitis C virus protease inhibitors. Curr Opin Virol 8:16–21
-
(2014)
Curr Opin Virol
, vol.8
, pp. 16-21
-
-
Kieffer, T.L.1
George, S.2
-
33
-
-
84946491226
-
Simeprevir in HCV genotype-1-infected patients: deep sequencing analyses of the PILLAR and ASPIRE Phase IIb trials
-
Lenz O, Fevery K, Thys K et al (2013) Simeprevir in HCV genotype-1-infected patients: deep sequencing analyses of the PILLAR and ASPIRE Phase IIb trials. Antiviral Ther 18 suppl 1A:14
-
(2013)
Antiviral Ther
, vol.18 suppl 1A
, pp. 14
-
-
Lenz, O.1
Fevery, K.2
Thys, K.3
|