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Volumn 51, Issue 1, 2009, Pages 106-108

Detection of hepatitis c mutants with natural resistance to ns3/4a protease inhibitors in hiv/hcv-coinfected individuals treated with antiretroviral therapy

Author keywords

[No Author keywords available]

Indexed keywords

AMPRENAVIR PHOSPHATE; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; ANTIRETROVIRUS AGENT; BOCEPREVIR; INDINAVIR; ITMN 191; LOPINAVIR; NELFINAVIR; NONSTRUCTURAL PROTEIN 3; NONSTRUCTURAL PROTEIN 3 PROTEINASE INHIBITOR; NONSTRUCTURAL PROTEIN 4A; NONSTRUCTURAL PROTEIN 4A PROTEINASE INHIBITOR; PEGINTERFERON ALPHA; PROTEINASE INHIBITOR; RIBAVIRIN; RITONAVIR; SAQUINAVIR; TELAPREVIR; UNCLASSIFIED DRUG;

EID: 67651148377     PISSN: 15254135     EISSN: None     Source Type: Journal    
DOI: 10.1097/QAI.0b013e3181a02fda     Document Type: Letter
Times cited : (18)

References (10)
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  • 2
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    • Malcolm, B.A.1    Liu, R.2    Lahser, F.3
  • 3
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  • 4
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    • Prongay AJ, Guo Z, Yao N. Discovery of the HCV NS3/4A protease inhibitor (1R,5S)-N-[3-amino-1-(cyclobutylmethyl)-2,3-dioxopropyl]-3-[2(S)-[[[(1, 1-dimethylethyl)amino]carbonyl] amino]-3,3-dimethyl-1-oxobutyl]-6,6-dimethyl-3- azabicyclo[3.1.0]hexan-2(S)-carboxamide (Sch 503034) II. Key steps in structurebased optimization. J Med Chem. 2007;50: 2310-2318.
  • 5
    • 46949111215 scopus 로고    scopus 로고
    • Preclinical characterisitics of ITMN-B, an orally active inhibitor of the HCV NS3/4A protease nominated for preclinical development
    • Seiwert SD, Andrews SW, Tan H, et al. Preclinical characterisitics of ITMN-B, an orally active inhibitor of the HCV NS3/4A protease nominated for preclinical development. J Hepatol. 2006;44:S278.
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  • 6
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  • 7
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  • 8
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    • De Francesco R, Carfi A. Advances in the development of new therapeutic agents targeting the NS3-4A serine protease or the NS5B RNA-dependent rNA polymerase of the hepatitis C virus. Adv Drug Deliv Rev. 2007; 59:1242-1262. [e-pub August 11, 2007]. Review.
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  • 10
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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.