The influence of the C5 substituent on the 2-thiouridine desulfuration pathway and the conformational analysis of the resulting 4-pyrimidinone products

Bioorganic and Medicinal Chemistry

Volumn 23, Issue 17, 2015, Pages 5587-5594

  Bartos, Paulina ^a   Ebenryter Olbinska, Katarzyna ^a   Sochacka, Elzbieta ^a   Nawrot, Barbara ^b  

^a LODZ UNIVERSITY OF TECHNOLOGY   (Poland)

^b POLISH ACADEMY OF SCIENCES   (Poland)

Author keywords

2 Thiouridine; 4 Pyrimidinone riboside; Conformational analysis; Desulfuration; Oxidative stress; tRNA

Indexed keywords

2 THIOURIDINE; 4 PYRIMIDINONE DERIVATIVE; 5 METHOXY 2 THIOURIDINE; 5 METHYLCARBOXYMETHYL 2 THIOURIDINE; NUCLEOSIDE; THIOURIDINE; UNCLASSIFIED DRUG; 2-THIOURIDINE; PYRIMIDINONE DERIVATIVE; TRANSFER RNA;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CHEMICAL BOND; CODON; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DESULFURIZATION; GLYCOSIDIC BOND; HYDROGEN BOND; MASS SPECTROMETRY; OXIDATIVE STRESS; PH MEASUREMENT; PROTON NUCLEAR MAGNETIC RESONANCE; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; ANALOGS AND DERIVATIVES; CHEMICAL STRUCTURE; CHEMISTRY; HUMAN; METABOLISM;

HUMANS; MODELS, MOLECULAR; OXIDATIVE STRESS; PYRIMIDINONES; RNA, TRANSFER; THIOURIDINE;

EID: 84946488346     PISSN: 09680896     EISSN: 14643391     Source Type: Journal    
DOI: 10.1016/j.bmc.2015.07.030     Document Type: Article

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