Expanding the threonine aldolase toolbox for the asymmetric synthesis of tertiary α-amino acids

Applied Microbiology and Biotechnology

Volumn 99, Issue 22, 2015, Pages 9651-9661

  Fesko, Kateryna ^a   Strohmeier, Gernot A ^a,b   Breinbauer, Rolf ^a,b  

^a GRAZ UNIVERSITY OF TECHNOLOGY   (Austria)

^b AUSTRIAN CENTRE OF INDUSTRIAL BIOTECHNOLOGY   (Austria)

Author keywords

Aldol reactions; Biocatalysis; Enzyme catalysis; Tertiary amino acids; Threonine aldolase

Indexed keywords

CARBON; CATALYSIS; CRYSTAL STRUCTURE; ENZYMES; ESCHERICHIA COLI; KETONES;

ALDOL REACTIONS; ALDOLASES; ASYMMETRIC SYNTHESIS; BIOCATALYSIS; BIOCHEMICAL PROPERTIES; BIOCHEMICAL SYNTHESIS; ENZYME CATALYSIS; STRUCTURE ALIGNMENT;

AMINO ACIDS;

ALPHA AMINO ACID; CARBON; FRUCTOSE BISPHOSPHATE ALDOLASE; PHENYLSERINE; THREONINE; THREONINE ALDOLASE; UNCLASSIFIED DRUG; AMINO ACID; GLYCINE HYDROXYMETHYLTRANSFERASE;

AMINO ACID; BACTERIUM; BIOCHEMICAL COMPOSITION; CATALYST; DATABASE; ENZYME ACTIVITY; GENE EXPRESSION; IDENTIFICATION METHOD;

ALDOL REACTION; AMINO ACID SEQUENCE; ARTICLE; ASYMMETRIC SYNTHESIS; CATALYSIS; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENANTIOSELECTIVITY; ENZYME PURIFICATION; ESCHERICHIA COLI; GENE EXPRESSION; GENE OVEREXPRESSION; KINETIC PARAMETERS; MOLECULAR CLONING; NONHUMAN; PROTEIN PURIFICATION; SEQUENCE ALIGNMENT; SEQUENCE DATABASE; AEROMONAS; BIOLOGY; BIOSYNTHESIS; CHEMISTRY; GENETICS; METABOLISM; PROCEDURES; PROTEIN CONFORMATION; PSEUDOMONAS; X RAY CRYSTALLOGRAPHY;

AEROMONAS; ESCHERICHIA COLI; PSEUDOMONAS SP.;

AEROMONAS; AMINO ACIDS; CLONING, MOLECULAR; COMPUTATIONAL BIOLOGY; CRYSTALLOGRAPHY, X-RAY; ESCHERICHIA COLI; GLYCINE HYDROXYMETHYLTRANSFERASE; PROTEIN CONFORMATION; PSEUDOMONAS;

EID: 84946485729     PISSN: 01757598     EISSN: 14320614     Source Type: Journal    
DOI: 10.1007/s00253-015-6803-y     Document Type: Article

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