Risk factors for discharge on a new antipsychotic medication after admission to an intensive care unit

Journal of Critical Care

Volumn 30, Issue 6, 2015, Pages 1283-1286

  Rowe, A Shaun ^a   Hamilton, Leslie A ^a   Curtis, Rachel A ^a   Davis, Camellia R ^a   Smith, Leslie N ^b   Peek, Grayson K ^c   Reynolds, Victoria W ^a  

^a UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^b METHODIST UNIVERSITY HOSPITAL   (United States)

^c DUKE UNIVERSITY HOSPITAL   (United States)

Author keywords

Antipsychotics; Benzodiazepines; Medication reconciliation; Opioids

Indexed keywords

BENZODIAZEPINE; HALOPERIDOL; QUETIAPINE; RISPERIDONE; TIOTIXENE; ZIPRASIDONE; BENZODIAZEPINE DERIVATIVE; NEUROLEPTIC AGENT;

ADULT; ARTICLE; CLINICAL EVALUATION; DELIRIUM; DRUG EFFECT; DRUG INDICATION; FEMALE; HIGH RISK PATIENT; HOSPITAL ADMISSION; HOSPITAL DISCHARGE; HUMAN; INTENSIVE CARE UNIT; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD REVIEW; MORTALITY; RISK FACTOR; TREATMENT OUTCOME; AGED; APACHE; MEDICATION ERROR; MIDDLE AGED; ODDS RATIO; RETROSPECTIVE STUDY; STATISTICS AND NUMERICAL DATA; UNIVERSITY HOSPITAL; VERY ELDERLY;

ACADEMIC MEDICAL CENTERS; ADULT; AGED; AGED, 80 AND OVER; ANTIPSYCHOTIC AGENTS; APACHE; BENZODIAZEPINES; DELIRIUM; FEMALE; HUMANS; INTENSIVE CARE UNITS; MALE; MEDICATION ERRORS; MIDDLE AGED; ODDS RATIO; PATIENT DISCHARGE; RETROSPECTIVE STUDIES; RISK FACTORS;

EID: 84946485679     PISSN: 08839441     EISSN: 15578615     Source Type: Journal    
DOI: 10.1016/j.jcrc.2015.08.009     Document Type: Article

References (16)

1. Ely E.W., Shintani A., Truman B., Speroff T., Gordon S.M., FE Harrell, et al. Delirium as a predictor of mortality in mechanically ventilated patients in the intensive care unit. J Am Med Assoc 2004, 291(14):1753-1762.
2. Lat I., McMillian W., Taylor S., Janzen J.M., Papadopoulos S., Korth L., et al. The impact of delirium on clinical outcomes in mechanically ventilated surgical and trauma patients. Crit Care Med 2009, 37(6):1898-1905.
3. Pisani M.A., Kong S.Y., Kasl S.V., Murphy T.E., Araujo K.L., Van Ness P.H. Days of delirium are associated with 1-year mortality in an older intensive care unit population. Am J Respir Crit Care 2009, 180(11):1092-1097.
4. Heymann A., Radtke F., Schiemann A., Lütz A., MacGuill M., Wernecke K.D., et al. Delayed treatment of delirium increases mortality rate in intensive care unit patients. J Int Med Res 2010, 38(5):1584-1595.
5. Devlin J.W., Bhat S., Roberts R.J., Skrobik Y. Current perceptions and practices surrounding the recognition and treatment of delirium in the intensive care unit: a survey of 250 critical care pharmacists from eight states. Ann Pharmacother 2011, 45(10):1217-1229.
6. Al-Qadheeb N.S., Balk E.M., Fraser G.L., Skrobik Y., Riker R.R., Kress J.P., et al. Randomized ICU trials do not demonstrate an association between interventions that reduce delirium duration and short-term mortality: a systematic review and meta-analysis. Crit Care Med 2014, 42(6):1442-1454.
7. Jasiak K.D., Middleton E.A., Camamo J.M., Erstad B.L., Snyder L.S., Huckleberry Y.C. Evaluation of discontinuation of atypical antipsychotics prescribed for ICU delirium. J Pharm Pract 2013, 26(3):253-256.
8. Jyrkka J., Enlund H., Korhonen M.J., Sulkava E.R., Hartikainen S. Polypharmacy status as an indicator of mortality in an elderly population. Drug Aging 2009, 26(12):1039-1048.
9. De Paepe P., Petrovic M., Outtier L., Van Maele G., Buylaert W. Drug interactions and adverse drug reactions in the older patients admitted to the emergency department. Acta Clin Belg 2013, 68(1):15-21.
10. Chen Y.C., Fan J.S., Chen M.H., Hsu T.F., Huang H.H., Cheng K.W., et al. Risk factors associated with adverse drug events among older adults in emergency department. Eur J Intern Med 2014, 25(1):49-55.
11. Aljishi M., Parekh K. Risk factors for general medicine readmissions and association with mortality. N Z Med J 2014, 127(1394):42-50.
12. Devlin J.W., Roberts R.J., Fong J.J., Skrobik Y., Riker R.R., Hill N.S., et al. Efficacy and safety of quetiapine in critically ill patients with delirium: a prospective, multicenter, randomized, double-blind, placebo-controlled pilot study. Crit Care Med 2010, 38(2):419-427.
13. Girard T.D., Pandharipande P.P., Carson S.S., Schmidt G.A., Wright P.E., Canonico A.E., et al. Feasibility, efficacy, and safety of antipsychotics for intensive care unit delirium: the MIND randomized, placebo-controlled trial. Crit Care Med 2010, 38(2):428-437.
14. Pandharipande P.P., Pun B.T., Herr D.L., Maze M., Girard T.D., Miller R.R., et al. Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial. J Am Med Assoc 2007, 298(22):2644-2653.
15. Riker R.R., Shehabi Y., Bokesch P.M., Ceraso D., Wisemandle W., Koura F., et al. Dexmedetomidine vs midazolam for sedation of critically ill patients: a randomized trial. J Am Med Assoc 2009, 301(5):489-499.
16. Hugtenburg J.G., Borgsteede S.D., Beckeringh J.J. Medication review and patient counselling at discharge from the hospital by community pharmacists. Pharm World Sci 2009, 31(6):630-637.