메뉴 건너뛰기




Volumn 141, Issue 12, 2015, Pages 2109-2120

Significances of contactin-1 expression in human gastric cancer and knockdown of contactin-1 expression inhibits invasion and metastasis of MKN45 gastric cancer cells

Author keywords

Contactin 1; Epithelial mesenchymal transition; Gastric cancer; Tumorigenicity

Indexed keywords

CONTACTIN 1; SHORT HAIRPIN RNA; TRANSCRIPTION FACTOR SLUG; CNTN1 PROTEIN, HUMAN; MESSENGER RNA; SMALL INTERFERING RNA; TUMOR MARKER;

EID: 84946482418     PISSN: 01715216     EISSN: 14321335     Source Type: Journal    
DOI: 10.1007/s00432-015-1973-7     Document Type: Article
Times cited : (33)

References (34)
  • 2
    • 0028306477 scopus 로고
    • Molecular cloning and in situ localization of the human contactin gene (CNTN1) on chromosome 12q11-q12
    • COI: 1:CAS:528:DyaK2MXitVWlsA%3D%3D, PID: 7959734
    • Berglund EO, Ranscht B (1994) Molecular cloning and in situ localization of the human contactin gene (CNTN1) on chromosome 12q11-q12. Genomics 21:571–582. doi:10.1006/geno.1994.1316
    • (1994) Genomics , vol.21 , pp. 571-582
    • Berglund, E.O.1    Ranscht, B.2
  • 4
    • 0036351317 scopus 로고    scopus 로고
    • Analysis of gene function in somatic mammalian cells using small interfering RNAs
    • COI: 1:CAS:528:DC%2BD38Xks1GhtLw%3D, PID: 12054897
    • Elbashir SM, Harborth J, Weber K, Tuschl T (2002) Analysis of gene function in somatic mammalian cells using small interfering RNAs. Methods 26:199–213. doi:10.1016/S1046-2023(02)00023-3
    • (2002) Methods , vol.26 , pp. 199-213
    • Elbashir, S.M.1    Harborth, J.2    Weber, K.3    Tuschl, T.4
  • 6
    • 0036814534 scopus 로고    scopus 로고
    • F3/contactin, a neuronal cell adhesion molecule implicated in axogenesis and myelination
    • COI: 1:CAS:528:DC%2BD38XovFers70%3D, PID: 12500940
    • Falk J, Bonnon C, Girault JA, Faivre-Sarrailh C (2002) F3/contactin, a neuronal cell adhesion molecule implicated in axogenesis and myelination. Biol Cell 94:327–334. doi:10.1016/S0248-4900(02)00006-0
    • (2002) Biol Cell , vol.94 , pp. 327-334
    • Falk, J.1    Bonnon, C.2    Girault, J.A.3    Faivre-Sarrailh, C.4
  • 7
    • 84918815964 scopus 로고    scopus 로고
    • Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012
    • COI: 1:CAS:528:DC%2BC2cXitVyktbzI, PID: 25220842
    • Ferlay J, Soerjomataram I, Dikshit R, Eser S, Mathers C, Rebelo M, Parkin DM, Forman D, Bray F (2015) Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012. Int J Cancer 136:E359–E386. doi:10.1002/ijc.29210
    • (2015) Int J Cancer , vol.136 , pp. 359-386
    • Ferlay, J.1    Soerjomataram, I.2    Dikshit, R.3    Eser, S.4    Mathers, C.5    Rebelo, M.6    Parkin, D.M.7    Forman, D.8    Bray, F.9
  • 9
    • 0029553183 scopus 로고
    • An overview of epithelio-mesenchymal transformation
    • COI: 1:STN:280:DyaK283otFSlsA%3D%3D, PID: 8714286
    • Hay ED (1995) An overview of epithelio-mesenchymal transformation. Acta Anat 154:8–20
    • (1995) Acta Anat , vol.154 , pp. 8-20
    • Hay, E.D.1
  • 10
    • 10744233414 scopus 로고    scopus 로고
    • F3/contactin acts as a functional ligand for Notch during oligodendrocyte maturation
    • COI: 1:CAS:528:DC%2BD3sXosFCqsL8%3D, PID: 14567914
    • Hu QD, Ang BT, Karsak M et al (2003) F3/contactin acts as a functional ligand for Notch during oligodendrocyte maturation. Cell 115:163–175. doi:10.1016/S0092-8674(03)00810-9
    • (2003) Cell , vol.115 , pp. 163-175
    • Hu, Q.D.1    Ang, B.T.2    Karsak, M.3
  • 11
    • 84901502942 scopus 로고    scopus 로고
    • EphA2 promotes epithelial–mesenchymal transition through the Wnt/β-catenin pathway in gastric cancer cells
    • COI: 1:CAS:528:DC%2BC3sXptV2rurw%3D, PID: 23752181
    • Huang J, Xiao D, Li G, Ma J, Chen P, Yuan W, Hou F, Ge J, Zhong M, Tang Y, Xia X, Chen Z (2014) EphA2 promotes epithelial–mesenchymal transition through the Wnt/β-catenin pathway in gastric cancer cells. Oncogene 33:2737–2747. doi:10.1038/onc.2013.238
    • (2014) Oncogene , vol.33 , pp. 2737-2747
    • Huang, J.1    Xiao, D.2    Li, G.3    Ma, J.4    Chen, P.5    Yuan, W.6    Hou, F.7    Ge, J.8    Zhong, M.9    Tang, Y.10    Xia, X.11    Chen, Z.12
  • 13
    • 84862907531 scopus 로고    scopus 로고
    • Regulation of matrix metalloproteinase genes by E2F transcription factors: Rb-Raf-1 interaction as a novel target for metastatic disease
    • COI: 1:CAS:528:DC%2BC38Xos1KktA%3D%3D, PID: 22086850
    • Johnson JL, Pillai S, Pernazza D, Sebti SM, Lawrence NJ, Chellappan SP (2012) Regulation of matrix metalloproteinase genes by E2F transcription factors: Rb-Raf-1 interaction as a novel target for metastatic disease. Cancer Res 72:516–526. doi:10.1158/0008-5472.CAN-11-2647
    • (2012) Cancer Res , vol.72 , pp. 516-526
    • Johnson, J.L.1    Pillai, S.2    Pernazza, D.3    Sebti, S.M.4    Lawrence, N.J.5    Chellappan, S.P.6
  • 15
    • 0034304507 scopus 로고    scopus 로고
    • The role of E-cadherin expression in non-small cell lung cancer
    • COI: 1:STN:280:DC%2BD3crhtFOhuw%3D%3D, PID: 11068984
    • Lim SC, Jang IG, Kim YC, Park KO (2000) The role of E-cadherin expression in non-small cell lung cancer. J Korean Med Sci 15:501–506
    • (2000) J Korean Med Sci , vol.15 , pp. 501-506
    • Lim, S.C.1    Jang, I.G.2    Kim, Y.C.3    Park, K.O.4
  • 17
    • 84864343472 scopus 로고    scopus 로고
    • Contactin-1 (CNTN-1) overexpression is correlated with advanced clinical stage and lymph node metastasis in oesophageal squamous cell carcinomas
    • PID: 22581910
    • Liu PF, Chen SM, Wu WT, Liu BT, Shen WD, Wang FJ, He XW, Zhang SY (2012) Contactin-1 (CNTN-1) overexpression is correlated with advanced clinical stage and lymph node metastasis in oesophageal squamous cell carcinomas. Jpn J Clin Oncol 42:612–618. doi:10.1093/jjco/hys066
    • (2012) Jpn J Clin Oncol , vol.42 , pp. 612-618
    • Liu, P.F.1    Chen, S.M.2    Wu, W.T.3    Liu, B.T.4    Shen, W.D.5    Wang, F.J.6    He, X.W.7    Zhang, S.Y.8
  • 18
    • 84869170531 scopus 로고    scopus 로고
    • Carcinoma of the stomach: a review of epidemiology, pathogenesis, molecular genetics and chemoprevention
    • PID: 22844547
    • Nagini S (2012) Carcinoma of the stomach: a review of epidemiology, pathogenesis, molecular genetics and chemoprevention. World J Gastrointest Oncol 4:156–169. doi:10.4251/wjgo.v4.i7.156
    • (2012) World J Gastrointest Oncol , vol.4 , pp. 156-169
    • Nagini, S.1
  • 19
    • 44449111555 scopus 로고    scopus 로고
    • Loss of E-cadherin promotes metastasis via multiple downstream transcriptional pathways
    • COI: 1:CAS:528:DC%2BD1cXlvVOitLw%3D, PID: 18483246
    • Onder TT, Gupta PB, Mani SA, Yang J, Lander ES, Weinberg RA (2008) Loss of E-cadherin promotes metastasis via multiple downstream transcriptional pathways. Cancer Res 68:3645–3654. doi:10.1158/0008-5472.CAN-07-2938
    • (2008) Cancer Res , vol.68 , pp. 3645-3654
    • Onder, T.T.1    Gupta, P.B.2    Mani, S.A.3    Yang, J.4    Lander, E.S.5    Weinberg, R.A.6
  • 20
    • 0035288499 scopus 로고    scopus 로고
    • A review of high-resolution X-ray computed tomography and other imaging modalities for small animal research
    • COI: 1:STN:280:DC%2BD3MzgvFyqsw%3D%3D
    • Paulus MJ, Gleason SS, Easterly ME, Foltz CJ (2001) A review of high-resolution X-ray computed tomography and other imaging modalities for small animal research. Lab Anim 30:36–45
    • (2001) Lab Anim , vol.30 , pp. 36-45
    • Paulus, M.J.1    Gleason, S.S.2    Easterly, M.E.3    Foltz, C.J.4
  • 21
    • 0346363757 scopus 로고    scopus 로고
    • Snail mediates E-cadherin repression by the recruitment of the Sin3A/histone deacetylase 1 (HDAC1)/HDAC2 complex
    • COI: 1:CAS:528:DC%2BD2cXhtVWmtQ%3D%3D, PID: 14673164
    • Peinado H, Ballestar E, Esteller M, Cano A (2004) Snail mediates E-cadherin repression by the recruitment of the Sin3A/histone deacetylase 1 (HDAC1)/HDAC2 complex. Mol Cell Biol 24:306–319. doi:10.1128/MCB.24.1.306-319.2004
    • (2004) Mol Cell Biol , vol.24 , pp. 306-319
    • Peinado, H.1    Ballestar, E.2    Esteller, M.3    Cano, A.4
  • 22
    • 80053128196 scopus 로고    scopus 로고
    • Effect of lentivirus-mediated shRNA targeting VEGFR-3 on proliferation, apoptosis and invasion of gastric cancer cells
    • COI: 1:CAS:528:DC%2BC3MXhtleku7jF, PID: 21805024
    • Qin XJ, Dai DJ, Gao ZG, Huan JL, Zhu L (2011) Effect of lentivirus-mediated shRNA targeting VEGFR-3 on proliferation, apoptosis and invasion of gastric cancer cells. Int J Mol Med 28:761–768. doi:10.3892/ijmm.2011.758
    • (2011) Int J Mol Med , vol.28 , pp. 761-768
    • Qin, X.J.1    Dai, D.J.2    Gao, Z.G.3    Huan, J.L.4    Zhu, L.5
  • 23
    • 0031034895 scopus 로고    scopus 로고
    • Induction of neurite outgrowth through contactin and Nr-CAM by extracellular regions of glial receptor tyrosine phosphatase beta
    • COI: 1:CAS:528:DyaK2sXhsVejtbg%3D, PID: 9049255
    • Sakurai T, Lustig M, Nativ M, Hemperly JJ, Schlessinger J, Peles E, Grumet M (1997) Induction of neurite outgrowth through contactin and Nr-CAM by extracellular regions of glial receptor tyrosine phosphatase beta. J Cell Biol 136:907–918. doi:10.1083/jcb.136.4.907
    • (1997) J Cell Biol , vol.136 , pp. 907-918
    • Sakurai, T.1    Lustig, M.2    Nativ, M.3    Hemperly, J.J.4    Schlessinger, J.5    Peles, E.6    Grumet, M.7
  • 24
    • 67049145076 scopus 로고    scopus 로고
    • Contactins: emerging key roles in the development and function of the nervous system
    • PID: 19262165
    • Shimoda Y, Watanabe K (2009) Contactins: emerging key roles in the development and function of the nervous system. Cell Adh Migr 3:64–70. doi:10.4161/cam.3.1.7764
    • (2009) Cell Adh Migr , vol.3 , pp. 64-70
    • Shimoda, Y.1    Watanabe, K.2
  • 25
    • 33645053494 scopus 로고    scopus 로고
    • Knockdown of contactin-1 expression suppresses invasion and metastasis of lung adenocarcinoma
    • COI: 1:CAS:528:DC%2BD28XhvV2htb8%3D, PID: 16510572
    • Su JL, Yang CY, Shih JY, Wei LH, Hsieh CY, Jeng YN, Wang NY, Yang PC, Kuo ML (2006a) Knockdown of contactin-1 expression suppresses invasion and metastasis of lung adenocarcinoma. Cancer Res 66:2553–2561. doi:10.1158/0008-5472.CAN-05-2645
    • (2006) Cancer Res , vol.66 , pp. 2553-2561
    • Su, J.L.1    Yang, C.Y.2    Shih, J.Y.3    Wei, L.H.4    Hsieh, C.Y.5    Jeng, Y.N.6    Wang, N.Y.7    Yang, P.C.8    Kuo, M.L.9
  • 27
    • 0027976632 scopus 로고
    • Initial events of myelination involve Fyn tyrosine kinase signalling
    • COI: 1:CAS:528:DyaK2cXhsF2lt7c%3D, PID: 7509042
    • Umemori H, Sato S, Yagi T, Aizawa S, Yamamoto T (1994) Initial events of myelination involve Fyn tyrosine kinase signalling. Nature 367:572–576. doi:10.1038/367572a0
    • (1994) Nature , vol.367 , pp. 572-576
    • Umemori, H.1    Sato, S.2    Yagi, T.3    Aizawa, S.4    Yamamoto, T.5
  • 29
    • 76949084622 scopus 로고    scopus 로고
    • TNF-alpha/NF-kappaB/Snail pathway in cancer cell migration and invasion
    • COI: 1:CAS:528:DC%2BC3cXitVWgtLo%3D, PID: 20087353
    • Wu Y, Zhou BP (2010) TNF-alpha/NF-kappaB/Snail pathway in cancer cell migration and invasion. Br J Cancer 102:639–644. doi:10.1038/sj.bjc.6605530
    • (2010) Br J Cancer , vol.102 , pp. 639-644
    • Wu, Y.1    Zhou, B.P.2
  • 30
    • 84878390356 scopus 로고    scopus 로고
    • Contactin-1 reduces E-cadherin expression via activating AKT in lung cancer
    • COI: 1:CAS:528:DC%2BC3sXptlyhur4%3D, PID: 23724143
    • Yan J, Wong N, Hung C, Chen WXY, Tang DM (2013) Contactin-1 reduces E-cadherin expression via activating AKT in lung cancer. PLoS One 8:e65463. doi:10.1371/journal.pone.0065463
    • (2013) PLoS One , vol.8 , pp. 65463
    • Yan, J.1    Wong, N.2    Hung, C.3    Chen, W.X.Y.4    Tang, D.M.5
  • 31
    • 80655125015 scopus 로고    scopus 로고
    • MicroRNA miR-21 regulates the metastatic behavior of B16 melanoma cells
    • COI: 1:CAS:528:DC%2BC3MXhsVSqt7fP, PID: 21940630
    • Yang CH, Yue JM, Pfeffer SR, Handorf CR, Pfeffer LM (2011) MicroRNA miR-21 regulates the metastatic behavior of B16 melanoma cells. J Biol Chem 286:39172–39178. doi:10.1074/jbc.M111.285098
    • (2011) J Biol Chem , vol.286 , pp. 39172-39178
    • Yang, C.H.1    Yue, J.M.2    Pfeffer, S.R.3    Handorf, C.R.4    Pfeffer, L.M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.