The role of E-cadherin expression in non-small cell lung cancer

Journal of Korean Medical Science

Volumn 15, Issue 5, 2000, Pages 501-506

  Lim, Sung Chul ^a,b   Jang, Il Gweon ^a   Kim, Young Chul ^a   Park, Kyung Ok ^a  

^a Chonnam National University   (South Korea)

^b Chonnam National University Medical School   (South Korea)

Author keywords

Cadherins; Lung Neoplasms; Lymph Nodes

Indexed keywords

CADHERIN; MONOCLONAL ANTIBODY;

ADULT; AGED; ARTICLE; BIOSYNTHESIS; CHEMISTRY; FEMALE; HUMAN; IMMUNOHISTOCHEMISTRY; IMMUNOLOGY; LUNG NON SMALL CELL CANCER; LUNG TUMOR; LYMPH NODE; MALE; METABOLISM; MIDDLE AGED; PATHOLOGY; PREDICTION AND FORECASTING; PROGNOSIS;

ADULT; AGED; AGED, 80 AND OVER; ANTIBODIES, MONOCLONAL; CADHERINS; CARCINOMA, NON-SMALL-CELL LUNG; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; LUNG NEOPLASMS; LYMPH NODES; MALE; MIDDLE AGED; PREDICTIVE VALUE OF TESTS; PROGNOSIS;

EID: 0034304507     PISSN: 10118934     EISSN: None     Source Type: Journal    
DOI: 10.3346/jkms.2000.15.5.501     Document Type: Article

References (29)

1. Nicolson GL. Cancer metastasis: tumor cell and host organ properties important in metastasis to specific secondary sites. Biochim Biophys Acta 1988; 948: 175-224.
2. Kramer RH, Nicolson GL. Interactions of tumor cells with vascular endothelial cell monolayers: a model for metastatic invasion. Proc Natl Acad Sci USA 1979; 76: 5704-8.
3. Terranova VP, Liotta LA, Russo RG, Martin GR. Role of laminin in the attachment and metastasis of marine tumor cells. Cancer Res 1982; 42: 2265-9.
4. Iwamoto Y, Robey FA, Graf J, Sasaki M, Kleinman HK, Yamada Y, Martin GR. YIGSR, a synthetic laminin penta-peptide, inhibits experimental metastasis formation. Science 1987; 238: 1132-4.
5. Takada A, Ohmori K, Takahashi N, Tsuyuoka K, Yago A, Zenita K, Hasegawa A, Kannagi R. Adhesion of human cancer cells to vascular endothelium mediated by a carbohydrate antigen, sialyl Lewis A. Biochem Biophys Res Commun 1991; 179: 713-9.
6. Birch M, Mitchell S, Hart IR. Isolation and characterization of human melanoma cell variants expressing high and low levels of CD44. Cancer Res 1991; 51: 6660-7.
7. Takeichi M. Cadherin cell adhesion receptors as a morphogenetic regulator. Science 1991; 251: 1451-5.
8. Schipper JH, Frixen UH, Behrens J, Unger A, Jahnke K, Birchmeier W. E-cadherin expression in squamous cell carcinomas of head and neck: Inverse correlation with tumor dedifferentiation and lymph node metastasis. Cancer Res 1991; 51: 6328-37.
9. Mayer B, Johnson JP, Leitl F, Jauch KW, Heiss MM, Schildberg FW, Birchmeier W, Funke I. E-cadherin expression in primary and metastatic gastric cancer: down-regulation correlates with cellular dedifferentiation and glandular disintegration. Cancer Res 1993; 53: 1690-5.
10. Behrens J, Mareel MM, Van Roy FM, Birchmeier W. Dissecting tumor cell invasion: epithelial cells acquire invasive properties after the loss of uvomorulin-mediated cell-cell adhesion. J Cell Biol 1989; 108: 2435-47.
11. Vleminckx K, Vakaet LJ, Mareel M, Fiers W, van Roy F. Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion suppressor role. Cell 1991; 66: 107-19.
12. Frixen UH, Behrens J, Sachs M, Eberle G, Voss B, Warda A, Lochner D, Birchmeier W. E-cadherin mediated cell-cell adhesion prevents invasiveness of human carcinoma cells. J Cell Biol 1991; 113: 173-85.
13. Mountain CF. Revisions in the International System for Staging Lung Cancer. Chest 1997; 111: 1710-7.
14. Liotta L, Steeg PS, Stetler-Stevenson WG. Cancer metastasis and angiogenesis: an imbalance of positive and negative regulation. Cell 1991; 64: 327-36.
15. Navarro P, Gomez M, Pizarro A, Gamallo M, Quintanilla M, Cano A. A role for the E-cadherin cell-cell adhesion molecule during tumor progression of mouse epidermal carcinogenesis. J Cell Biol 1991; 115: 517-33.
16. Yoshida-Noro C, Suzuki N, Takeichi M. Molecular nature of the calcium-dependent cell-cell adhesion system in mouse teratocarcinoma and embryonic cells studied with a monoclonal antibody. Dev Biol 1984; 101: 19-27.
17. Duband JL, Dufour S, Hatta K, Takeichi M, Edelman GM, Thiery JP. Adhesion molecules during somitogenesis in the avian embryo. J Cell Biol 1987; 104: 1361-74.
18. Nagafuchi A, Shirayoshi Y, Okazaki K, Yasuda K, Takeichi M. Transformation of cell adhesion properties by exogenously introduced E-cadherin cDNA. Nature 1987; 329: 341-3.
19. Nose A, Nagafuchi A, Takeichi M. Isolation of placental cadherin cDNA: identification of a novel gene family of cell-cell adhesion molecule. EMBO J 1987; 6: 3655-61.
20. Hatta K, Takeichi M. Expression of N-cadherin adhesion molecules associated with early morphogenetic events in chick development. Nature 1986; 320: 447-9.
21. Gallin WJ, Sorkin BC, Edelman G, Cunningham BA, Sequence analysis of a cDNA clone encoding the liver cell adhesion molecule, L-CAM. Proc Natl Acad Sci USA 1987; 84: 2808-12.
22. 2+ dependent cell-cell adhesion molecule in endothelial cells. J Cell Biol 1990; 110: 1745-56.
23. Shimoyama Y, Hirohashi S, Hirano S, Noguchi M, Shimosato Y, Takeichi M, Abe O. Cadherin cell-adhesion molecules in human epithelial tissues and carcinomas. Cancer Res 1989; 49: 2128-33.
24. Mareel MM, Behrens J, Birchmeier W, De Bruyne GK, Vleminckx K, Hoogewijs A, Fiers WC, Van Roy FM. Down-regulation of E-cadherin expression in Madin Darby canine kidney (MDCK) cells inside tumors of nude mice. Int J Cancer 1991; 47: 922-8.
25. Frixen UH, Behrens J, Sachs M, Eberle G, Voss B, Warda A, Lochner D, Birchmeier W. E-cadherin mediated cell-cell adhesion prevents invasiveness of human carcinoma cells. J Cell Biol 1991; 113: 173-85.
26. Sulzer MA, Leers MP, van Noord JA, Bollen EC, Theunissen PH. Reduced E-cadherin expression is associated with increased lymph node metastasis and unfavorable prognosis in non-small cell lung cancer. Am J Respir Crit Care Med 1998; 157: 1319-23.
27. Bohm M, Totzeck B, Wieland I. Differences of E-cadherin expression levels and patterns in human lung cancer. Ann Hematol 1994; 68: 81-3.
28. Oka H, Shiozaki H, Kobayashi K, Tahara H, Tamura S, Miyata M, Doki Y, Iihara K, Matsuyoshi N, Hirano S, Takeichi M, Mori T. Immunohistochemical evaluation of E-cadherin adhesion molecule expression in human gastric cancer. Virchows Arch A Pathol Anat Histopathol 1992; 421: 149-56.
29. Shimoyama Y, Hirohashi S. Expression of E- and P-cadherin in gastric carcinomas. Cancer Res 1991; 51: 2185-92.