Schizophrenia symptoms and brain network efficiency: A resting-state fMRI study

Psychiatry Research - Neuroimaging

Volumn 234, Issue 2, 2015, Pages 208-218

  Su, Tsung Wei ^a,b   Hsu, Tun Wei ^a   Lin, Yi Ching ^b   Lin, Ching Po ^a  

^a NATIONAL YANG MING UNIVERSITY   (Taiwan)

^b Ministry of Health and Welfare ^*  (Taiwan)

Author keywords

Brain efficiency; Positive and Negative Symptom Scale; Psychotic symptom; Resting state fMRI; Small world network

Indexed keywords

ADULT; AMYGDALOID NUCLEUS; ANXIETY DISORDER; ARTICLE; CLINICAL ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; DEPRESSION; EXCITEMENT; FEMALE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HIPPOCAMPUS; HUMAN; MALE; MENTAL PATIENT; NEGATIVE SYNDROME; NUCLEAR MAGNETIC RESONANCE SCANNER; POSITIVE AND NEGATIVE SYNDROME SCALE; PRIORITY JOURNAL; RESTING STATE NETWORK; SCHIZOPHRENIA; SUPERIOR FRONTAL GYRUS; SYMPTOMATOLOGY; BRAIN; BRAIN MAPPING; CROSS-SECTIONAL STUDY; MENTAL DISEASE; METABOLISM; MIDDLE AGED; NERVE CELL NETWORK; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOLOGY; PHYSIOLOGY; PROCEDURES; REST;

ADULT; BRAIN; BRAIN MAPPING; CROSS-SECTIONAL STUDIES; DEPRESSION; FEMALE; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; NERVE NET; PSYCHOPATHOLOGY; REST; SCHIZOPHRENIA;

EID: 84946479970     PISSN: 09254927     EISSN: 18727506     Source Type: Journal    
DOI: 10.1016/j.pscychresns.2015.09.013     Document Type: Article

References (64)

1. Achard S., Bullmore E. Efficiency and cost of economical brain functional networks. PLoS Comput. Biol. 2007, 3:e17.
2. Adler L.E., Olincy A., Waldo M., Harris J.G., Griffith J., Stevens K., Flach K., Nagamoto H., Bickford P., Leonard S. Schizophrenia, sensory gating, and nicotinic receptors. Schizophr. Bull. 1998, 24:189-202.
3. Aleman A., Kahn R.S. Strange feelings: do amygdala abnormalities dysregulate the emotional brain in schizophrenia?. Prog. Neurobiol. 2005, 77:283-298.
4. Alexander-Bloch A.F., Gogtay N., Meunier D., Birn R., Clasen L., Lalonde F., Lenroot R., Giedd J., Bullmore E.T. Disrupted modularity and local connectivity of brain functional networks in childhood-onset schizophrenia. Front. Syst. Neurosci. 2010, 4:147.
5. Bassett D.S., Bullmore E. Small-world brain networks. Neuroscientist 2006, 12:512-523.
6. Bassett D.S., Bullmore E.T., Meyer-Lindenberg A., Apud J.A., Weinberger D.R., Coppola R. Cognitive fitness of cost-efficient brain functional networks. Proc. Natl. Acad. Sci. 2009, 106:11747-11752.
7. Birn R.M., Murphy K., Bandettini P.A. The effect of respiration variations on independent component analysis results of resting state functional connectivity. Hum. Brain Mapp. 2008, 29:740-750.
8. Biswal B., Zerrin Yetkin F., Haughton V.M., Hyde J.S. Functional connectivity in the motor cortex of resting human brain using echo-planar mri. Magn. Reson. Med. 1995, 34:537-541.
9. Boyer P., Phillips J.L., Rousseau F.L., Ilivitsky S. Hippocampal abnormalities and memory deficits: new evidence of a strong pathophysiological link in schizophrenia. Brain Res. Rev. 2007, 54:92-112.
10. Brent B.K., Seidman L.J., Thermenos H.W., Holt D.J., Keshavan M.S. Self-disturbances as a possible premorbid indicator of schizophrenia risk: a neurodevelopmental perspective. Schizophr. Res. 2014, 152:73-80.
11. Cabral J., Kringelbach M., Deco G. Functional graph alterations in schizophrenia: a result from a global anatomic decoupling?. Pharmacopsychiatry 2012, 45:S57.
12. Cao M., Wang J.-H., Dai Z.-J., Cao X.-Y., Jiang L.-L., Fan F.-M., Song X.-W., Xia M.-R., Shu N., Dong Q. Topological organization of the human brain functional connectome across the lifespan. Dev. Cogn. Neurosci. 2014, 7:76-93.
13. Chao-Gan Y., Yu-Feng Z. DPARSF: a MATLAB toolbox for "pipeline" data analysis of resting-state fMRI. Front. Syst. Neurosci. 2010, 4:13.
14. Dosenbach N.U., Nardos B., Cohen A.L., Fair D.A., Power J.D., Church J.A., Nelson S.M., Wig G.S., Vogel A.C., Lessov-Schlaggar C.N. Prediction of individual brain maturity using fMRI. Science 2010, 329:1358-1361.
15. Dunbar R.I. The social brain hypothesis and its implications for social evolution. Ann. Hum. Biol. 2009, 36:562-572.
16. Emsley R., Rabinowitz J., Torreman M., Group R.-I.-E.P.G.W. The factor structure for the Positive and Negative Syndrome Scale (PANSS) in recent-onset psychosis. Schizophr. Res. 2003, 61:47-57.
17. Fair D.A., Cohen A.L., Power J.D., Dosenbach N.U., Church J.A., Miezin F.M., Schlaggar B.L., Petersen S.E. Functional brain networks develop from a "local to distributed" organization. PLoS Comput. Biol. 2009, 5:e1000381.
18. Fornito A., Zalesky A., Pantelis C., Bullmore E.T. Schizophrenia, neuroimaging and connectomics. NeuroImage 2012, 62:2296-2314.
19. Fresán A., De la Fuente-Sandoval C., Loyzaga C., Garcia-Anaya M., Meyenberg N., Nicolini H., Apiquián R. A forced five-dimensional factor analysis and concurrent validity of the Positive and Negative Syndrome Scale in Mexican schizophrenic patients. Schizophr. Res. 2005, 72:123-129.
20. Friston K.J., Frith C.D. Schizophrenia: a disconnection syndrome. Clin. Neurosci. 1995, 3:89-97.
21. Goldman M.B., Mitchell C.P. What is the functional significance of hippocampal pathology in schizophrenia?. Schizophr. Bull. 2004, 30:367-392.
22. Harary F. Graph Theory 1969, Addison-Wesley, Reading, MA.
23. He H., Sui J., Yu Q., Turner J.A., Ho B.-C., Sponheim S.R., Manoach D.S., Clark V.P., Calhoun V.D. Altered small-world brain networks in schizophrenia patients during working memory performance. PloS One 2012, 7:e38195.
24. He Y., Chen Z.J., Evans A.C. Small-world anatomical networks in the human brain revealed by cortical thickness from MRI. Cereb. Cortex 2007, 17:2407-2419.
25. He Y., Dagher A., Chen Z., Charil A., Zijdenbos A., Worsley K., Evans A. Impaired small-world efficiency in structural cortical networks in multiple sclerosis associated with white matter lesion load. Brain 2009, 132:3366-3379. (awp089).
26. Hsu T.-W., Wu C.W., Cheng Y.-F., Chen H.-L., Lu C.-H., Cho K.-H., Lin W.-C., Lin C.-P. Impaired small-world network efficiency and dynamic functional distribution in patients with cirrhosis. PLoS One 2012, 7:e35266.
27. Kay S.R., Flszbein A., Opfer L.A. The positive and negative syndrome scale (PANSS) for schizophrenia. Schizophr. Bull. 1987, 13:261.
28. Kim J.-H., Kim S.-Y., Lee J., Oh K.-J., Kim Y.-B., Cho Z.-H. Evaluation of the factor structure of symptoms in patients with schizophrenia. Psychiatry Res. 2012, 197:285-289.
29. Latora V., Marchiori M. Efficient behavior of small-world networks. Phys. Rev. Lett. 2001, 87:198701.
30. Latora V., Marchiori M. Economic small-world behavior in weighted networks. Eur. Phys. J. B - Matter Complex Syst. 2003, 32:249-263.
31. Levine S.Z., Rabinowitz J. Revisiting the 5 dimensions of the Positive and Negative Syndrome Scale. J. Clin. Psychopharmacol. 2007, 27:431-436.
32. Liang M., Zhou Y., Jiang T., Liu Z., Tian L., Liu H., Hao Y. Widespread functional disconnectivity in schizophrenia with resting-state functional magnetic resonance imaging. NeuroReport 2006, 17:209-213.
33. Lindenmayer J.-P., Grochowski S., Hyman R.B. Five factor model of schizophrenia: replication across samples. Schizophr. Res. 1995, 14:229-234.
34. Liu Y., Liang M., Zhou Y., He Y., Hao Y., Song M., Yu C., Liu H., Liu Z., Jiang T. Disrupted small-world networks in schizophrenia. Brain 2008, 131:945-961.
35. Lowe M., Mock B., Sorenson J. Functional connectivity in single and multislice echoplanar imaging using resting-state fluctuations. Neuroimage 1998, 7:119-132.
36. Lynall M.-E., Bassett D.S., Kerwin R., McKenna P.J., Kitzbichler M., Muller U., Bullmore E. Functional connectivity and brain networks in schizophrenia. The. J. Neurosci. 2010, 30:9477-9487.
37. Manoliu A., Riedl V., Doll A., Bäuml J.G., Mühlau M., Schwerthöffer D., Scherr M., Zimmer C., Förstl H., Bäuml J. Insular dysfunction reflects altered between-network connectivity and severity of negative symptoms in schizophrenia during psychotic remission. Front. Hum. Neurosci. 2013, 7:216.
38. McDonald A.J. Cortical pathways to the mammalian amygdala. Prog. Neurobiol. 1998, 55:257-332.
39. Micheloyannis S., Pachou E., Stam C.J., Breakspear M., Bitsios P., Vourkas M., Erimaki S., Zervakis M. Small-world networks and disturbed functional connectivity in schizophrenia. Schizophr. Res. 2006, 87:60-66.
40. Oldfield R.C. The assessment and analysis of handedness: the Edinburgh inventory. Neuropsychologia 1971, 9:97-113.
41. Power J.D., Barnes K.A., Snyder A.Z., Schlaggar B.L., Petersen S.E. Spurious but systematic correlations in functional connectivity MRI networks arise from subject motion. Neuroimage 2012, 59:2142-2154.
42. Rotarska-Jagiela A., van de Ven V., Oertel-Knöchel V., Uhlhaas P.J., Vogeley K., Linden D.E. Resting-state functional network correlates of psychotic symptoms in schizophrenia. Schizophr. Res. 2010, 117:21-30.
43. Rubinov M., Sporns O. Complex network measures of brain connectivity: uses and interpretations. Neuroimage 2010, 52:1059-1069.
44. Sheehan D., Lecrubier Y., Sheenhan K. The Mini-International Neuropsychiatric Interview (MINI): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10. J. Clin. Psychiatry 1998, 59:22-33.
45. Skudlarski P., Jagannathan K., Anderson K., Stevens M.C., Calhoun V.D., Skudlarska B.A., Pearlson G. Brain connectivity is not only lower but different in schizophrenia: a combined anatomical and functional approach. Biol. Psychiatry 2010, 68:61-69.
46. Smith S.M., Jenkinson M., Woolrich M.W., Beckmann C.F., Behrens T.E., Johansen-Berg H., Bannister P.R., De Luca M., Drobnjak I., Flitney D.E. Advances in functional and structural MR image analysis and implementation as FSL. Neuroimage 2004, 23:S208-S219.
47. Sporns O. The human connectome: a complex network. Ann. N.Y. Acad. Sci. 2011, 1224:109-125.
48. Su T.-W., Lan T.-H., Hsu T.-W., Biswal B.B., Tsai P.-J., Lin W.-C., Lin C.-P. Reduced neuro-integration from the dorsolateral prefrontal cortex to the whole brain and executive dysfunction in schizophrenia patients and their relatives. Schizophr. Res. 2013, 148:50-58.
49. Tamminga C.A., Stan A.D., Wagner A.D. The hippocampal formation in schizophrenia. Am. J. Psychiatry 2010, 167:1178-1193.
50. Tzourio-Mazoyer N., Landeau B., Papathanassiou D., Crivello F., Etard O., Delcroix N., Mazoyer B., Joliot M. Automated anatomical labeling of activations in SPM using a macroscopic anatomical parcellation of the MNI MRI single-subject brain. Neuroimage 2002, 15:273-289.
51. van den Heuvel M.P., Mandl R.C., Stam C.J., Kahn R.S., Pol H.E.H. Aberrant frontal and temporal complex network structure in schizophrenia: a graph theoretical analysis. J. Neurosci. 2010, 30:15915-15926.
52. Van Overwalle F. Social cognition and the brain: a meta-analysis. Hum. Brain Mapp. 2009, 30:829-858.
53. van Wijk B.C., Stam C.J., Daffertshofer A. Comparing brain networks of different size and connectivity density using graph theory. PLoS One 2010, 5:e13701.
54. Wang J., Zuo X., Dai Z., Xia M., Zhao Z., Zhao X., Jia J., Han Y., He Y. Disrupted functional brain connectome in individuals at risk for Alzheimer's disease. Biol. Psychiatry 2013, 73:472-481.
55. Wang J., Zuo X., He Y. Graph-based network analysis of resting-state functional MRI. Front. Syst. Neurosci. 2010, 4.
56. Wang Q., Su T.-P., Zhou Y., Chou K.-H., Chen I.-Y., Jiang T., Lin C.-P. Anatomical insights into disrupted small-world networks in schizophrenia. Neuroimage 2012, 59:1085-1093.
57. Watts D.J., Strogatz S.H. Collective dynamics of 'small-world'networks. Nature 1998, 393:440-442.
58. White L., Harvey P.D., Opler L., Lindenmayer J. Empirical assessment of the factorial structure of clinical symptoms in schizophrenia. A multisite, multimodel evaluation of the factorial structure of the Positive and Negative Syndrome Scale. The PANSS Study Group. Psychopathology 1997, 30:263-274.
59. Whitfield-Gabrieli S., Thermenos H.W., Milanovic S., Tsuang M.T., Faraone S.V., McCarley R.W., Shenton M.E., Green A.I., Nieto-Castanon A., LaViolette P. Hyperactivity and hyperconnectivity of the default network in schizophrenia and in first-degree relatives of persons with schizophrenia. Proc. Natl. Acad. Sci. 2009, 106:1279-1284.
60. Woodward N.D., Rogers B., Heckers S. Functional resting-state networks are differentially affected in schizophrenia. Schizophr. Res. 2011, 130:86-93.
61. Yamada M., Ueda K., Namiki C., Hirao K., Hayashi T., Ohigashi Y., Murai T. Social cognition in schizophrenia: similarities and differences of emotional perception from patients with focal frontal lesions. Eur. Arch. Psychiatry Clin. Neurosci. 2009, 259:227-233.
62. Yu Q., Sui J., Rachakonda S., He H., Gruner W., Pearlson G., Kiehl K.A., Calhoun V.D. Altered topological properties of functional network connectivity in schizophrenia during resting state: a small-world brain network study. PloS One 2011, 6:e25423.
63. Zalesky A., Fornito A., Seal M.L., Cocchi L., Westin C.-F., Bullmore E.T., Egan G.F., Pantelis C. Disrupted axonal fiber connectivity in schizophrenia. Biol. Psychiatry 2011, 69:80-89.
64. Zhang J., Wang J., Wu Q., Kuang W., Huang X., He Y., Gong Q. Disrupted brain connectivity networks in drug-naive, first-episode major depressive disorder. Biol. Psychiatry 2011, 70:334-342.