A Peptide Uncoupling BDNF Receptor TrkB from Phospholipase Cγ1 Prevents Epilepsy Induced by Status Epilepticus

Neuron

Volumn 88, Issue 3, 2015, Pages 484-491

  Gu, Bin ^a,c   Huang, Yang Zhong ^a   He, Xiao Ping ^a   Joshi, Rasesh B ^b,d   Jang, Wonjo ^a,e   McNamara, James O ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b Duke University   (United States)

^c UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^d WAKE FOREST SCHOOL OF MEDICINE   (United States)

^e MEDICAL COLLEGE OF GEORGIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; KAINIC ACID; PEPTIDE DERIVATIVE; PHOSPHOLIPASE C GAMMA1; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE KINASE INHIBITOR; PY816 PEPTIDE; UNCLASSIFIED DRUG; PEPTIDE FRAGMENT; PHOSPHOLIPASE C GAMMA; UNCOUPLING PROTEIN;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTICONVULSANT ACTIVITY; ANXIETY DISORDER; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DOSE TIME EFFECT RELATION; DRUG MECHANISM; DRUG PROTEIN BINDING; DRUG SELECTIVITY; DRUG TARGETING; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME BINDING; ENZYME INHIBITION; EPILEPTIC STATE; HIPPOCAMPAL CA1 REGION; HIPPOCAMPAL CA3 REGION; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PYRAMIDAL NERVE CELL; SEIZURE; TEMPORAL LOBE EPILEPSY; 129 MOUSE; AMINO ACID SEQUENCE; ANIMAL; C57BL MOUSE; EPILEPSY; FEMALE; GENETICS; HIPPOCAMPUS; HUMAN; MALE; METABOLISM; MOLECULAR GENETICS; RAT; SPRAGUE DAWLEY RAT; STATUS EPILEPTICUS; TRANSGENIC MOUSE;

AMINO ACID SEQUENCE; ANIMALS; EPILEPSY; FEMALE; HIPPOCAMPUS; HUMANS; MALE; MICE; MICE, 129 STRAIN; MICE, INBRED C57BL; MICE, TRANSGENIC; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; PHOSPHOLIPASE C GAMMA; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, TRKB; STATUS EPILEPTICUS; UNCOUPLING AGENTS;

EID: 84946121478     PISSN: 08966273     EISSN: 10974199     Source Type: Journal    
DOI: 10.1016/j.neuron.2015.09.032     Document Type: Article

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