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Volumn 290, Issue 44, 2015, Pages 26549-26561

ATG4B (Autophagin-1) Phosphorylation modulates autophagy

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; LIPIDS; PROTEINS;

EID: 84946100784     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.658088     Document Type: Article
Times cited : (76)

References (38)
  • 1
    • 1842583789 scopus 로고    scopus 로고
    • Development by self-digestion: Molecular mechanisms and biological functions of autophagy
    • Levine, B., and Klionsky, D. J. (2004) Development by self-digestion: molecular mechanisms and biological functions of autophagy. Dev. Cell 6, 463-477
    • (2004) Dev. Cell , vol.6 , pp. 463-477
    • Levine, B.1    Klionsky, D.J.2
  • 2
    • 77956404377 scopus 로고    scopus 로고
    • Eaten alive: A history of macroautophagy
    • Yang, Z., and Klionsky, D. J. (2010) Eaten alive: a history of macroautophagy. Nature Cell Biol. 12, 814-822
    • (2010) Nature Cell Biol. , vol.12 , pp. 814-822
    • Yang, Z.1    Klionsky, D.J.2
  • 4
    • 0034676037 scopus 로고    scopus 로고
    • The reversible modification regulates the membrane-binding state of Apg8/ Aut7 essential for autophagy and the cytoplasm to vacuole targeting pathway
    • Kirisako, T., Ichimura, Y., Okada, H., Kabeya, Y., Mizushima, N., Yoshimori, T., Ohsumi, M., Takao, T., Noda, T., and Ohsumi, Y. (2000) The reversible modification regulates the membrane-binding state of Apg8/ Aut7 essential for autophagy and the cytoplasm to vacuole targeting pathway. J. Cell Biol. 151, 263-276
    • (2000) J. Cell Biol. , vol.151 , pp. 263-276
    • Kirisako, T.1    Ichimura, Y.2    Okada, H.3    Kabeya, Y.4    Mizushima, N.5    Yoshimori, T.6    Ohsumi, M.7    Takao, T.8    Noda, T.9    Ohsumi, Y.10
  • 6
    • 43949143804 scopus 로고    scopus 로고
    • The Atg16L complex specifies the site of LC3 lipidation for membrane biogenesis in autophagy
    • Fujita, N., Itoh, T., Omori, H., Fukuda, M., Noda, T., and Yoshimori, T. (2008) The Atg16L complex specifies the site of LC3 lipidation for membrane biogenesis in autophagy. Mol. Biol. Cell 19, 2092-2100
    • (2008) Mol. Biol. Cell , vol.19 , pp. 2092-2100
    • Fujita, N.1    Itoh, T.2    Omori, H.3    Fukuda, M.4    Noda, T.5    Yoshimori, T.6
  • 7
    • 3242888703 scopus 로고    scopus 로고
    • LC3, GABARAP and GATE16 localize to autophagosomal membrane depending on form-II formation
    • Kabeya, Y., Mizushima, N., Yamamoto, A., Oshitani-Okamoto, S., Ohsumi, Y., and Yoshimori, T. (2004) LC3, GABARAP and GATE16 localize to autophagosomal membrane depending on form-II formation. J. Cell Sci. 117, 2805-2812
    • (2004) J. Cell Sci. , vol.117 , pp. 2805-2812
    • Kabeya, Y.1    Mizushima, N.2    Yamamoto, A.3    Oshitani-Okamoto, S.4    Ohsumi, Y.5    Yoshimori, T.6
  • 8
    • 77953122645 scopus 로고    scopus 로고
    • LC3 and GATE-16/GABARAP subfamilies are both essential yet act differently in autophagosome biogenesis
    • Weidberg, H., Shvets, E., Shpilka, T., Shimron, F., Shinder, V., and Elazar, Z. (2010) LC3 and GATE-16/GABARAP subfamilies are both essential yet act differently in autophagosome biogenesis. EMBO J. 29, 1792-1802
    • (2010) EMBO J. , vol.29 , pp. 1792-1802
    • Weidberg, H.1    Shvets, E.2    Shpilka, T.3    Shimron, F.4    Shinder, V.5    Elazar, Z.6
  • 9
    • 0347695019 scopus 로고    scopus 로고
    • A single protease, Apg4B, is specific for the autophagy-related ubiquitin-like proteins GATE-16, MAP1-LC3, GABARAP, and Apg8L
    • Hemelaar, J., and Lelyveld., V. S., Kessler, B. M., and Ploegh, H. L. (2003) A single protease, Apg4B, is specific for the autophagy-related ubiquitin-like proteins GATE-16, MAP1-LC3, GABARAP, and Apg8L. J. Biol. Chem. 278, 51841-51850
    • (2003) J. Biol. Chem. , vol.278 , pp. 51841-51850
    • Hemelaar, J.1    Lelyveld, V.S.2    Kessler, B.M.3    Ploegh, H.L.4
  • 10
    • 9144224360 scopus 로고    scopus 로고
    • Human light chain 3/MAP1LC3B is cleaved at its carboxyl-terminal Met121 to expose Gly120 for lipidation and targetingto autophagosomal membranes
    • Tanida, I., Ueno, T., and Kominami, E. (2004) Human light chain 3/MAP1LC3B is cleaved at its carboxyl-terminal Met121 to expose Gly120 for lipidation and targetingto autophagosomal membranes. J. Biol. Chem. 279, 47704-47710
    • (2004) J. Biol. Chem. , vol.279 , pp. 47704-47710
    • Tanida, I.1    Ueno, T.2    Kominami, E.3
  • 12
    • 0037423403 scopus 로고    scopus 로고
    • Human autophagins, a family of cysteine proteinases potentially implicated in cell degradation by autophagy
    • Mariño, G., Uría, J. A., Puente, X. S., Quesada, V., Bordallo, J., and López-Otin, C. (2003) Human autophagins, a family of cysteine proteinases potentially implicated in cell degradation by autophagy. J. Biol. Chem. 278, 3671-3678
    • (2003) J. Biol. Chem. , vol.278 , pp. 3671-3678
    • Mariño, G.1    Uría, J.A.2    Puente, X.S.3    Quesada, V.4    Bordallo, J.5    López-Otin, C.6
  • 13
    • 79953190772 scopus 로고    scopus 로고
    • Kinetics comparisons of mammalian Atg4 homologues indicate selective preferences toward diverse Atg8 substrates
    • Li, M., Hou, Y., Wang, J., Chen, X., and Shao., Z. M., and Yin, X. M. (2011) Kinetics comparisons of mammalian Atg4 homologues indicate selective preferences toward diverse Atg8 substrates. J. Biol. Chem. 286, 7327-7338
    • (2011) J. Biol. Chem. , vol.286 , pp. 7327-7338
    • Li, M.1    Hou, Y.2    Wang, J.3    Chen, X.4    Shao, Z.M.5    Yin, X.M.6
  • 15
    • 4344604111 scopus 로고    scopus 로고
    • HsAtg4B/HsApg4B/autophagin-1 cleaves the carboxyl termini of three human Atg8 homologues and delipidates microtubule-associated protein light chain 3- and GABAA receptor-associated protein-phospholipid conjugates
    • Tanida, I., and Sou., Y. S., Ezaki, J., Minematsu-Ikeguchi, N., Ueno, T., and Kominami, E. (2004) HsAtg4B/HsApg4B/autophagin-1 cleaves the carboxyl termini of three human Atg8 homologues and delipidates microtubule-associated protein light chain 3- and GABAA receptor-associated protein-phospholipid conjugates. J. Biol. Chem. 279, 36268-36276
    • (2004) J. Biol. Chem. , vol.279 , pp. 36268-36276
    • Tanida, I.1    Sou, Y.S.2    Ezaki, J.3    Minematsu-Ikeguchi, N.4    Ueno, T.5    Kominami, E.6
  • 17
  • 18
    • 58149398233 scopus 로고    scopus 로고
    • Atg4B(C74A) hampers autophagosome closure: A useful protein for inhibiting autophagy
    • Fujita, N., Noda, T., and Yoshimori, T. (2009) Atg4B(C74A) hampers autophagosome closure: a useful protein for inhibiting autophagy. Autophagy 5, 88-89
    • (2009) Autophagy , vol.5 , pp. 88-89
    • Fujita, N.1    Noda, T.2    Yoshimori, T.3
  • 22
    • 34247186472 scopus 로고    scopus 로고
    • Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4
    • Scherz-Shouval, R., Shvets, E., Fass, E., Shorer, H., Gil, L., and Elazar, Z. (2007) Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4. EMBO J. 26, 1749-1760
    • (2007) EMBO J. , vol.26 , pp. 1749-1760
    • Scherz-Shouval, R.1    Shvets, E.2    Fass, E.3    Shorer, H.4    Gil, L.5    Elazar, Z.6
  • 23
    • 33846610475 scopus 로고    scopus 로고
    • Protein phosphorylation and expression profiling by Yin-yang multidimensional liquid chromatography (Yin-yang MDLC) mass spectrometry
    • Dai, J., and Jin., W. H., Sheng, Q. H., Shieh, C. H., and Wu., J. R., and Zeng, R. (2007) Protein phosphorylation and expression profiling by Yin-yang multidimensional liquid chromatography (Yin-yang MDLC) mass spectrometry. J. Proteome Res. 6, 250-262
    • (2007) J. Proteome Res. , vol.6 , pp. 250-262
    • Dai, J.1    Jin, W.H.2    Sheng, Q.H.3    Shieh, C.H.4    Wu, J.R.5    Zeng, R.6
  • 24
    • 33750456519 scopus 로고    scopus 로고
    • Global, in vivo, and site-specific phosphorylation dynamics in signaling networks
    • Olsen, J. V., Blagoev, B., Gnad, F., Macek, B., Kumar, C., Mortensen, P., and Mann, M. (2006) Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. Cell 127, 635-648
    • (2006) Cell , vol.127 , pp. 635-648
    • Olsen, J.V.1    Blagoev, B.2    Gnad, F.3    Macek, B.4    Kumar, C.5    Mortensen, P.6    Mann, M.7
  • 26
    • 44149105911 scopus 로고    scopus 로고
    • PHOSIDA (phosphorylation site database): Management, structural and evolutionary investigation, and prediction of phosphosites
    • Gnad, F., Ren, S., Cox, J., Olsen, J. V., Macek, B., Oroshi, M., and Mann, M. (2007) PHOSIDA (phosphorylation site database): management, structural and evolutionary investigation, and prediction of phosphosites. Genome Biol. 8, R250
    • (2007) Genome Biol. , vol.8 , pp. R250
    • Gnad, F.1    Ren, S.2    Cox, J.3    Olsen, J.V.4    Macek, B.5    Oroshi, M.6    Mann, M.7
  • 27
    • 77957656800 scopus 로고    scopus 로고
    • Synthetic substrates for measuring activity of autophagy proteases: Autophagins (Atg4)
    • Shu, C. W., Drag, M., Bekes, M., Zhai, D., and Salvesen., G. S., and Reed, J. C. (2010) Synthetic substrates for measuring activity of autophagy proteases: autophagins (Atg4). Autophagy 6, 936-947
    • (2010) Autophagy , vol.6 , pp. 936-947
    • Shu, C.W.1    Drag, M.2    Bekes, M.3    Zhai, D.4    Salvesen, G.S.5    Reed, J.C.6
  • 28
    • 77955352128 scopus 로고    scopus 로고
    • Keap1 facilitates p62-mediated ubiquitin aggregate clearance via autophagy
    • Fan, W., Tang, Z., Chen, D., Moughon, D., Ding, X., Chen, S., Zhu, M., and Zhong, Q. (2010) Keap1 facilitates p62-mediated ubiquitin aggregate clearance via autophagy. Autophagy 6, 614-621
    • (2010) Autophagy , vol.6 , pp. 614-621
    • Fan, W.1    Tang, Z.2    Chen, D.3    Moughon, D.4    Ding, X.5    Chen, S.6    Zhu, M.7    Zhong, Q.8
  • 29
    • 47149091700 scopus 로고    scopus 로고
    • A pathway sensor for genome-wide screens of intracellular proteolytic cleavage
    • Ketteler, R., Sun, Z., Kovacs, K. F., and He., W. W., and Seed, B. (2008) A pathway sensor for genome-wide screens of intracellular proteolytic cleavage. Genome Biol. 9, R64
    • (2008) Genome Biol. , vol.9 , pp. R64
    • Ketteler, R.1    Sun, Z.2    Kovacs, K.F.3    He, W.W.4    Seed, B.5
  • 32
    • 28844502647 scopus 로고    scopus 로고
    • Structural basis for the specificity and catalysis of human Atg4B responsible for mammalian autophagy
    • Sugawara, K., and Suzuki., N. N., Fujioka, Y., Mizushima, N., Ohsumi, Y., and Inagaki, F. (2005) Structural basis for the specificity and catalysis of human Atg4B responsible for mammalian autophagy. The J. Biol. Chem. 280, 40058-40065
    • (2005) The J. Biol. Chem. , vol.280 , pp. 40058-40065
    • Sugawara, K.1    Suzuki, N.N.2    Fujioka, Y.3    Mizushima, N.4    Ohsumi, Y.5    Inagaki, F.6
  • 33
    • 65649136884 scopus 로고    scopus 로고
    • The structure of Atg4B-LC3 complex reveals the mechanism of LC3 processing and delipidation during autophagy
    • Satoo, K., and Noda., N. N., Kumeta, H., Fujioka, Y., Mizushima, N., Ohsumi, Y., and Inagaki, F. (2009) The structure of Atg4B-LC3 complex reveals the mechanism of LC3 processing and delipidation during autophagy. EMBO J. 28, 1341-1350
    • (2009) EMBO J. , vol.28 , pp. 1341-1350
    • Satoo, K.1    Noda, N.N.2    Kumeta, H.3    Fujioka, Y.4    Mizushima, N.5    Ohsumi, Y.6    Inagaki, F.7
  • 34
    • 50249122545 scopus 로고    scopus 로고
    • Quantitation of autophagy by luciferase release assay
    • Ketteler, R., and Seed, B. (2008) Quantitation of autophagy by luciferase release assay. Autophagy 4, 801-806
    • (2008) Autophagy , vol.4 , pp. 801-806
    • Ketteler, R.1    Seed, B.2
  • 35
    • 80052388263 scopus 로고    scopus 로고
    • A monitoring method for Atg4 activation in living cells using peptide-conjugated polymeric nanoparticles
    • Choi, K. M., and Nam., H. Y., Na, J. H., Kim, S. W., and Kim., S. Y., Kim, K., Kwon, I. C., and Ahn, H. J. (2011) A monitoring method for Atg4 activation in living cells using peptide-conjugated polymeric nanoparticles. Autophagy 7, 1052-1062
    • (2011) Autophagy , vol.7 , pp. 1052-1062
    • Choi, K.M.1    Nam, H.Y.2    Na, J.H.3    Kim, S.W.4    Kim, S.Y.5    Kim, K.6    Kwon, I.C.7    Ahn, H.J.8
  • 38
    • 84857256919 scopus 로고    scopus 로고
    • Atg4 recycles inappropriately lipidated Atg8 to promote autophagosome biogenesis
    • Nakatogawa, H., Ishii, J., Asai, E., and Ohsumi, Y. (2012) Atg4 recycles inappropriately lipidated Atg8 to promote autophagosome biogenesis. Autophagy 8, 177-186
    • (2012) Autophagy , vol.8 , pp. 177-186
    • Nakatogawa, H.1    Ishii, J.2    Asai, E.3    Ohsumi, Y.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.