-
1
-
-
79952232216
-
Global cancer statistics
-
Jemal, A. et al. Global cancer statistics. CA Cancer J Clin 61, 69-90 (2011
-
(2011)
CA Cancer J Clin
, vol.61
, pp. 69-90
-
-
Jemal, A.1
-
2
-
-
77955635233
-
Cancer statistics, 2010
-
Jemal, A., Siegel, R., Xu, J. & Ward, E. Cancer statistics, 2010. CA Cancer J Clin 60, 277-300 (2010
-
(2010)
CA Cancer J Clin
, vol.60
, pp. 277-300
-
-
Jemal, A.1
Siegel, R.2
Xu, J.3
Ward, E.4
-
3
-
-
77953930730
-
Gefitinib or chemotherapy for non-small-cell lung cancer with mutated EGFR
-
Maemondo, M. et al. Gefitinib or chemotherapy for non-small-cell lung cancer with mutated EGFR. N Engl J Med 362, 2380-2388 (2010
-
(2010)
N Engl J Med
, vol.362
, pp. 2380-2388
-
-
Maemondo, M.1
-
4
-
-
12444345511
-
Comparison of p53 mutations between adenocarcinoma and squamous cell carcinoma of the lung: Unique spectra involving g to a transitions and g to t transversions in both histologic types
-
Gao, W. M. et al. Comparison of p53 mutations between adenocarcinoma and squamous cell carcinoma of the lung: unique spectra involving G to A transitions and G to T transversions in both histologic types. Lung Cancer 40, 141-150 (2003
-
(2003)
Lung Cancer
, vol.40
, pp. 141-150
-
-
Gao, W.M.1
-
5
-
-
77953304209
-
Epha2 mutation in lung squamous cell carcinoma promotes increased cell survival, cell invasion, focal adhesions, and mammalian target of rapamycin activation
-
Faoro, L. et al. EphA2 mutation in lung squamous cell carcinoma promotes increased cell survival, cell invasion, focal adhesions, and mammalian target of rapamycin activation. The Journal of biological chemistry 285, 18575-18585 (2010
-
(2010)
The Journal of Biological Chemistry
, vol.285
, pp. 18575-18585
-
-
Faoro, L.1
-
6
-
-
77953139490
-
Nfe2l2 gene mutation in male Japanese squamous cell carcinoma of the lung
-
Sasaki, H. et al. NFE2L2 gene mutation in male Japanese squamous cell carcinoma of the lung. J Thorac Oncol 5, 786-789 (2010
-
(2010)
J Thorac Oncol
, vol.5
, pp. 786-789
-
-
Sasaki, H.1
-
7
-
-
70349278438
-
Activating e17k mutation in the gene encoding the protein kinase akt1 in a subset of squamous cell carcinoma of the lung
-
Viglietto, G. Activating E17K mutation in the gene encoding the protein kinase AKT1 in a subset of squamous cell carcinoma of the lung. Cell Cycle 8, 2869-2870 (2009
-
(2009)
Cell Cycle
, vol.8
, pp. 2869-2870
-
-
Viglietto, G.1
-
8
-
-
65249093808
-
Somatic alterations of the serine/threonine kinase lkb1 gene in squamous cell (scc) and large cell (lcc) lung carcinoma
-
Strazisar, M., Mlakar, V., Rott, T. & Glavac, D. Somatic alterations of the serine/threonine kinase LKB1 gene in squamous cell (SCC) and large cell (LCC) lung carcinoma. Cancer Invest 27, 407-416 (2009
-
(2009)
Cancer Invest
, vol.27
, pp. 407-416
-
-
Strazisar, M.1
Mlakar, V.2
Rott, T.3
Glavac, D.4
-
9
-
-
33745689525
-
Erbb2 kinase domain mutation in the lung squamous cell carcinoma
-
Lee, J. W. et al. ERBB2 kinase domain mutation in the lung squamous cell carcinoma. Cancer Lett 237, 89-94 (2006
-
(2006)
Cancer Lett
, vol.237
, pp. 89-94
-
-
Lee, J.W.1
-
10
-
-
70350641014
-
Sox2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas
-
Bass, A. J. et al. SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas. Nat Genet 41, 1238-1242 (2009
-
(2009)
Nat Genet
, vol.41
, pp. 1238-1242
-
-
Bass, A.J.1
-
11
-
-
78650451788
-
Frequent and focal fgfr1 amplification associates with therapeutically tractable fgfr1 dependency in squamous cell lung cancer
-
Weiss, J. et al. Frequent and focal FGFR1 amplification associates with therapeutically tractable FGFR1 dependency in squamous cell lung cancer. Sci Transl Med 2, 62ra93 (2010
-
(2010)
Sci Transl Med
, vol.2
, pp. 62ra93
-
-
Weiss, J.1
-
12
-
-
73549108711
-
Amplification of chromosomal segment 4q12 in non-small cell lung cancer
-
Ramos, A. H. et al. Amplification of chromosomal segment 4q12 in non-small cell lung cancer. Cancer Biol Ther 8, 2042-2050 (2009
-
(2009)
Cancer Biol Ther
, vol.8
, pp. 2042-2050
-
-
Ramos, A.H.1
-
13
-
-
84866894408
-
Comprehensive genomic characterization of squamous cell lung cancers
-
Hammerman, P. S. et al. Comprehensive genomic characterization of squamous cell lung cancers. Nature, 489, 519-525 (2012
-
(2012)
Nature
, vol.489
, pp. 519-525
-
-
Hammerman, P.S.1
-
14
-
-
84897018525
-
Integrative and comparative genomic analysis of lung squamous cell carcinomas in east asian patients
-
Kim, Y. et al. Integrative and comparative genomic analysis of lung squamous cell carcinomas in East asian patients. J Clin Oncol 32, 121-128 (2014
-
(2014)
J Clin Oncol
, vol.32
, pp. 121-128
-
-
Kim, Y.1
-
15
-
-
0037152628
-
Tobacco smoke carcinogens DNA damage and p53 mutations in smoking-Associated cancers
-
Pfeifer, G. P. et al. Tobacco smoke carcinogens, DNA damage and p53 mutations in smoking-Associated cancers. Oncogene 21, 7435-7451 (2002
-
(2002)
Oncogene
, vol.21
, pp. 7435-7451
-
-
Pfeifer, G.P.1
-
16
-
-
26244447845
-
Cadherin-10 is a novel blood-brain barrier adhesion molecule in human and mouse
-
Williams, M. J., Lowrie, M. B., Bennett, J. P., Firth, J. A., Clark, P. Cadherin-10 is a novel blood-brain barrier adhesion molecule in human and mouse. Brain research 1058, 62-72 (2005
-
(2005)
Brain Research
, vol.1058
, pp. 62-72
-
-
Williams, M.J.1
Lowrie, M.B.2
Bennett, J.P.3
Firth, J.A.4
Clark, P.5
-
17
-
-
38949129724
-
Etiologic value of p53 mutation spectra and differences with histology in lung cancers
-
Shimmyo, T. et al. Etiologic value of p53 mutation spectra and differences with histology in lung cancers. Cancer Sci 99, 287-295 (2008
-
(2008)
Cancer Sci
, vol.99
, pp. 287-295
-
-
Shimmyo, T.1
-
18
-
-
0033227089
-
Comprehensive analysis of p53 gene mutation characteristics in lung carcinoma with special reference to histological subtypes
-
Fujita, T., Kiyama, M., Tomizawa, Y., Kohno, T. & Yokota, J. Comprehensive analysis of p53 gene mutation characteristics in lung carcinoma with special reference to histological subtypes. Int J Oncol 15, 927-934 (1999
-
(1999)
Int J Oncol
, vol.15
, pp. 927-934
-
-
Fujita, T.1
Kiyama, M.2
Tomizawa, Y.3
Kohno, T.4
Yokota, J.5
-
19
-
-
33750885385
-
Dysfunctional keap1-nrf2 interaction in non-small-cell lung cancer
-
Singh, A. et al. Dysfunctional KEAP1-NRF2 interaction in non-small-cell lung cancer. PLoS Med 3, e420 (2006
-
(2006)
PLoS Med
, vol.3
, pp. e420
-
-
Singh, A.1
-
20
-
-
76749106638
-
Oncogenic nrf2 mutations in squamous cell carcinomas of oesophagus and skin
-
Kim, Y. R. et al. Oncogenic NRF2 mutations in squamous cell carcinomas of oesophagus and skin. J Pathol 220, 446-451 (2010
-
(2010)
J Pathol
, vol.220
, pp. 446-451
-
-
Kim, Y.R.1
-
21
-
-
84898600834
-
Identification of somatic mutations in EGFR/kras/alk-negative lung adenocarcinoma in never-smokers
-
Ahn, J. W. et al. Identification of somatic mutations in EGFR/KRAS/ALK-negative lung adenocarcinoma in never-smokers. Genome medicine 6, 18 (2014
-
(2014)
Genome Medicine
, vol.6
, pp. 18
-
-
Ahn, J.W.1
-
22
-
-
84885735554
-
Mutational landscape and significance across 12 major cancer types
-
Kandoth, C. et al. Mutational landscape and significance across 12 major cancer types. Nature 502, 333-339 (2013
-
(2013)
Nature
, vol.502
, pp. 333-339
-
-
Kandoth, C.1
-
23
-
-
0033004896
-
The human cadherin-10 gene: Complete coding sequence, predominant expression in the brain, and mapping on chromosome 5p13-14
-
Kools, P., Vanhalst, K., Van den Eynde, E. & van Roy, F. The human cadherin-10 gene: complete coding sequence, predominant expression in the brain, and mapping on chromosome 5p13-14. FEBS Lett 452, 328-334 (1999
-
(1999)
FEBS Lett
, vol.452
, pp. 328-334
-
-
Kools, P.1
Vanhalst, K.2
Van Den Eynde, E.3
Van Roy, F.4
-
24
-
-
78751703950
-
Molecular mechanisms of the keap1-nrf2 pathway in stress response and cancer evolution
-
Taguchi, K., Motohashi, H. & Yamamoto, M. Molecular mechanisms of the Keap1-Nrf2 pathway in stress response and cancer evolution. Genes Cells 16, 123-140 (2011
-
(2011)
Genes Cells
, vol.16
, pp. 123-140
-
-
Taguchi, K.1
Motohashi, H.2
Yamamoto, M.3
-
25
-
-
77954695549
-
Nrf2 and keap1 abnormalities in non-small cell lung carcinoma and association with clinicopathologic features
-
Solis, L. M. et al. Nrf2 and Keap1 abnormalities in non-small cell lung carcinoma and association with clinicopathologic features. Clin Cancer Res 16, 3743-3753 (2010
-
(2010)
Clin Cancer Res
, vol.16
, pp. 3743-3753
-
-
Solis, L.M.1
-
26
-
-
33344469643
-
Oxidative and electrophilic stresses activate nrf2 through inhibition of ubiquitination activity of keap1
-
Kobayashi, A. et al. Oxidative and electrophilic stresses activate Nrf2 through inhibition of ubiquitination activity of Keap1. Mol Cell Biol 26, 221-229 (2006
-
(2006)
Mol Cell Biol
, vol.26
, pp. 221-229
-
-
Kobayashi, A.1
-
27
-
-
54549094903
-
Somatic mutations affect key pathways in lung adenocarcinoma
-
Ding, L. et al. Somatic mutations affect key pathways in lung adenocarcinoma. Nature 455, 1069-1075 (2008
-
(2008)
Nature
, vol.455
, pp. 1069-1075
-
-
Ding, L.1
-
28
-
-
84884482254
-
The mutational landscape of chromatin regulatory factors across 4,623 tumor samples
-
Gonzalez-Perez, A., Jene-Sanz, A. & Lopez-Bigas, N. The mutational landscape of chromatin regulatory factors across 4,623 tumor samples. Genome biology 14, r106 (2013
-
(2013)
Genome Biology
, vol.14
, pp. r106
-
-
Gonzalez-Perez, A.1
Jene-Sanz, A.2
Lopez-Bigas, N.3
-
29
-
-
79251635938
-
Exome sequencing identifies frequent mutation of the swi/snf complex gene pbrm1 in renal carcinoma
-
Varela, I. et al. Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma. Nature 469, 539-542 (2011
-
(2011)
Nature
, vol.469
, pp. 539-542
-
-
Varela, I.1
-
30
-
-
80052266351
-
Frequent mutations of chromatin remodeling genes in transitional cell carcinoma of the bladder
-
Gui, Y. et al. Frequent mutations of chromatin remodeling genes in transitional cell carcinoma of the bladder. Nat Genet 43, 875-878 (2011
-
(2011)
Nat Genet
, vol.43
, pp. 875-878
-
-
Gui, Y.1
-
31
-
-
84870532434
-
Exome sequencing of serous endometrial tumors identifies recurrent somatic mutations in chromatinremodeling and ubiquitin ligase complex genes
-
Le Gallo, M. et al. Exome sequencing of serous endometrial tumors identifies recurrent somatic mutations in chromatinremodeling and ubiquitin ligase complex genes. Nat Genet 44, 1310-1315 (2012
-
(2012)
Nat Genet
, vol.44
, pp. 1310-1315
-
-
Le Gallo, M.1
-
32
-
-
84859899141
-
An integrated genomic approach identifies arid1a as a candidate tumor-suppressor gene in breast cancer
-
Mamo, A. et al. An integrated genomic approach identifies ARID1A as a candidate tumor-suppressor gene in breast cancer. Oncogene 31, 2090-2100 (2012
-
(2012)
Oncogene
, vol.31
, pp. 2090-2100
-
-
Mamo, A.1
-
33
-
-
84865168855
-
Identification of somatic mutations in non-small cell lung carcinomas using whole-exome sequencing
-
Liu, P. et al. Identification of somatic mutations in non-small cell lung carcinomas using whole-exome sequencing. Carcinogenesis 33, 1270-1276 (2012
-
(2012)
Carcinogenesis
, vol.33
, pp. 1270-1276
-
-
Liu, P.1
-
34
-
-
0036147076
-
Loss of heterozygosity as a predictor to map tumor suppressor genes in cancer: Molecular basis of its occurrence
-
Thiagalingam, S. et al. Loss of heterozygosity as a predictor to map tumor suppressor genes in cancer: molecular basis of its occurrence. Curr Opin Oncol 14, 65-72 (2002
-
(2002)
Curr Opin Oncol
, vol.14
, pp. 65-72
-
-
Thiagalingam, S.1
-
35
-
-
20144370942
-
A survey of homozygous deletions in human cancer genomes
-
Cox, C. et al. A survey of homozygous deletions in human cancer genomes. Proc Natl Acad Sci USA 102, 4542-4547 (2005
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 4542-4547
-
-
Cox, C.1
-
36
-
-
80052177544
-
Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in notch1
-
Agrawal, N. et al. Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1. Science 333, 1154-1157 (2011
-
(2011)
Science
, vol.333
, pp. 1154-1157
-
-
Agrawal, N.1
-
37
-
-
0036120562
-
The cadherin-catenin adhesion system in signaling and cancer
-
Conacci-Sorrell, M., Zhurinsky, J. & Ben-Ze'ev, A. The cadherin-catenin adhesion system in signaling and cancer. J Clin Invest 109, 987-991 (2002
-
(2002)
J Clin Invest
, vol.109
, pp. 987-991
-
-
Conacci-Sorrell, M.1
Zhurinsky, J.2
Ben-Ze'Ev, A.3
-
38
-
-
79952298459
-
Yap1 acts downstream of alpha-catenin to control epidermal proliferation
-
Schlegelmilch, K. et al. Yap1 acts downstream of alpha-catenin to control epidermal proliferation. Cell 144, 782-795 (2011
-
(2011)
Cell
, vol.144
, pp. 782-795
-
-
Schlegelmilch, K.1
-
39
-
-
0031742474
-
Dysregulation of the e-cadherin/catenin complex by irreversible mutations in human carcinomas
-
Berx, G., Nollet, F. & van Roy, F. Dysregulation of the E-cadherin/catenin complex by irreversible mutations in human carcinomas. Cell Adhes Commun 6, 171-184 (1998
-
(1998)
Cell Adhes Commun
, vol.6
, pp. 171-184
-
-
Berx, G.1
Nollet, F.2
Van Roy, F.3
-
40
-
-
79961087833
-
E-cadherin mediates contact inhibition of proliferation through hippo signalingpathway components
-
Kim, N. G., Koh, E., Chen, X., Gumbiner, B. M. E-cadherin mediates contact inhibition of proliferation through Hippo signalingpathway components. Proc Natl Acad Sci USA 108, 11930-11935 (2011
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 11930-11935
-
-
Kim, N.G.1
Koh, E.2
Chen, X.3
Gumbiner, B.M.4
-
41
-
-
79960997489
-
The hippo pathway in organ size control, tissue regeneration and stem cell self-renewal
-
Zhao, B., Tumaneng, K. & Guan, K. L. The Hippo pathway in organ size control, tissue regeneration and stem cell self-renewal. Nat Cell Biol 13, 877-883 (2011
-
(2011)
Nat Cell Biol
, vol.13
, pp. 877-883
-
-
Zhao, B.1
Tumaneng, K.2
Guan, K.L.3
-
42
-
-
67649884743
-
Fast and accurate short read alignment with burrows-wheeler transform
-
Li, H. & Durbin, R. Fast and accurate short read alignment with Burrows-Wheeler transform. Bioinformatics 25, 1754-1760 (2009
-
(2009)
Bioinformatics
, vol.25
, pp. 1754-1760
-
-
Li, H.1
Durbin, R.2
-
43
-
-
84946045268
-
-
(Date of access: 23/06/2012
-
Picard-tools. http://picard.sourceforge.net, (2011) (Date of access: 23/06/2012
-
(2011)
Picard-Tools
-
-
-
44
-
-
77956295988
-
The genome analysis toolkit: A mapreduce framework for analyzing next-generation DNA sequencing data
-
McKenna, A. et al. The Genome Analysis Toolkit: a MapReduce framework for analyzing next-generation DNA sequencing data. Genome Res 20, 1297-1303 (2010
-
(2010)
Genome Res
, vol.20
, pp. 1297-1303
-
-
McKenna, A.1
-
45
-
-
84863229597
-
Varscan 2: Somatic mutation and copy number alteration discovery in cancer by exome sequencing
-
Koboldt, D. C. et al. VarScan 2: somatic mutation and copy number alteration discovery in cancer by exome sequencing. Genome Res 22, 568-576 (2012
-
(2012)
Genome Res
, vol.22
, pp. 568-576
-
-
Koboldt, D.C.1
-
46
-
-
77956534324
-
Annovar: Functional annotation of genetic variants from high-throughput sequencing data
-
Wang, K., Li, M. & Hakonarson, H. ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data. Nucleic Acids Res 38, e164 (2010
-
(2010)
Nucleic Acids Res
, vol.38
, pp. e164
-
-
Wang, K.1
Li, M.2
Hakonarson, H.3
-
47
-
-
80052266351
-
Frequent mutations of chromatin remodeling genes in transitional cell carcinoma of the bladder
-
Gui, Y. et al. Frequent mutations of chromatin remodeling genes in transitional cell carcinoma of the bladder. Nat Genet 43, 875-878 (2011
-
(2011)
Nat Genet
, vol.43
, pp. 875-878
-
-
Gui, Y.1
-
48
-
-
34547926839
-
Lkb1 modulates lung cancer differentiation and metastasis
-
Ji, H. et al. LKB1 modulates lung cancer differentiation and metastasis. Nature 448, 807-810 (2007
-
(2007)
Nature
, vol.448
, pp. 807-810
-
-
Ji, H.1
-
49
-
-
33645518095
-
K-ras activation generates an inflammatory response in lung tumors
-
Ji, H. et al. K-ras activation generates an inflammatory response in lung tumors. Oncogene 25, 2105-2112 (2006
-
(2006)
Oncogene
, vol.25
, pp. 2105-2112
-
-
Ji, H.1
|