Biocompounds attenuating the development of obesity and insulin resistance produced by a high-fat sucrose diet

Natural Product Communications

Volumn 10, Issue 8, 2015, Pages 1417-1420

  Etxeberria, Usune ^a   De La Garza, Ana Laura ^a   Alfredo Martinez J ^a,b   Milagro, Fermín I ^a,b  

^a UNIVERSITY OF NAVARRA   (Spain)

^b Instituto de Salud Carlos III   (Spain)

Author keywords

Anti obesity; Chlorogenic acid; Coumaric acid; Curcumin; Leucine; Naringin

Indexed keywords

ADENYLATE KINASE; AURANTIIN; CHLOROGENIC ACID; COUMARIC ACID; CURCUMIN; LEUCINE; FAT INTAKE; FLAVANONE DERIVATIVE; GLUCOSE BLOOD LEVEL; SUCROSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CLINICAL EFFECTIVENESS; CONTROLLED STUDY; DIET SUPPLEMENTATION; ENERGY EXPENDITURE; FOOD INTAKE; GASTROCNEMIUS MUSCLE; GLUCOSE TOLERANCE TEST; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; INTRAABDOMINAL FAT; LIPID DIET; LIPID METABOLISM; LIVER; MALE; NONHUMAN; OBESITY; RAT; SPLEEN; SUGAR INTAKE; WEIGHT GAIN; ADVERSE EFFECTS; ANALYSIS; ANIMAL; FAT INTAKE; GLUCOSE BLOOD LEVEL; HUMAN; METABOLISM; WISTAR RAT;

ANIMALS; BLOOD GLUCOSE; CHLOROGENIC ACID; COUMARIC ACIDS; CURCUMIN; DIET, HIGH-FAT; DIETARY FATS; DIETARY SUPPLEMENTS; FLAVANONES; HUMANS; INSULIN RESISTANCE; LEUCINE; MALE; OBESITY; RATS; RATS, WISTAR; SUCROSE;

EID: 84945994563     PISSN: 1934578X     EISSN: 15559475     Source Type: Journal    
DOI: 10.1177/1934578x1501000826     Document Type: Article

References (26)

1. WHO. World Health Organization. Obesity and overweight. 2015 [Available from: http://www.who.int/mediacentre/factsheets/fs311/en/].
2. Jung UJ, Choi MS. (2014) Obesity and its metabolic complications: the role of adipokines and the relationship between obesity, inflammation, insulin resistance, dyslipidemia and nonalcoholic fatty liver disease. International Journal of Molecular Sciences, 15, 6184-6223.
3. Withrow D, Alter DA. (2011) The economic burden of obesity worldwide: a systematic review of the direct costs of obesity. Obesity Reviews, 12, 131-141.
4. Hoey H. (2014) Management of obesity in children differs from that of adults. The Proceedings of the Nutrition Society, 73, 519-525.
5. Manning S, Pucci A, Finer N. (2014) Pharmacotherapy for obesity: novel agents and paradigms. Therapeutic Advances in Chronic Disease, 5, 135-148.
6. Vasudeva N, Yadav N, Sharma SK. (2012) Natural products: a safest approach for obesity. Chinese Journal of Integrative Medicine, 18, 473-480.
7. Alves N, Valdes S, Silveira C, Duarte-Martino H, Milagro FI, Moreno-Aliaga MJ, Ribeiro S. (2012) Studies on mechanistic role of natural bioactive compounds in the management of obesity an overview. The Open Nutraceuticas Journal 5, 193-206.
8. de la Garza AL, Etxeberria U, Palacios-Ortega S, Haslberger AG, Aumueller E, Milagro FI, Martinez JA. (2014) Modulation of hyperglycemia and TNFalpha-mediated inflammation by helichrysum and grapefruit extracts in diabetic db/db mice. Food & Function, 5, 2120-2128.
9. Gonzalez-Castejon M, Rodriguez-Casado A. (2011) Dietary phytochemicals and their potential effects on obesity: a review. Pharmacological Research, 64, 438-455.
10. Zhang Y, Guo K, LeBlanc RE, Loh D, Schwartz GJ, Yu YH. (2007) Increasing dietary leucine intake reduces diet-induced obesity and improves glucose and cholesterol metabolism in mice via multimechanisms. Diabetes, 56, 1647-1654.
11. van Duynhoven J, Vaughan EE, Jacobs DM, Kemperman RA, van Velzen EJ, Gross G, Roger LC, Possemiers S, Smilde AK, Dore J, Westerhuis JA, Van de Wiele T. (2011) Metabolic fate of polyphenols in the human superorganism. Proceedings of the National Academy of Sciences of the United States of America, 108 Supplement 1, 4531-4538.
12. Lomba A, Milagro FI, Garcia-Diaz DF, Marti A, Campion J, Martinez JA. (2010) Obesity induced by a pair-fed high fat sucrose diet: methylation and expression pattern of genes related to energy homeostasis. Lipids in Health and Disease, 9, 60. Doi: 10.1186/1476-511X-9-60.
13. Dulloo AG. (2011) The search for compounds that stimulate thermogenesis in obesity management: from pharmaceuticals to functional food ingredients. Obesity Reviews, 12, 866-883.
14. Pu P, Gao DM, Mohamed S, Chen J, Zhang J, Zhou XY, Zhou NJ, Xie J, Jiang H. (2012) Naringin ameliorates metabolic syndrome by activating AMP-activated protein kinase in mice fed a high-fat diet. Archives of Biochemistry and Biophysics, 518, 61-70.
15. Hsu CL, Wu CH, Huang SL, Yen GC. (2009) Phenolic compounds rutin and o-coumaric acid ameliorate obesity induced by high-fat diet in rats. Journal of Agricultural and Food Chemistry, 57, 425-431.
16. Hsu CL, Yen GC. (2008) Phenolic compounds: evidence for inhibitory effects against obesity and their underlying molecular signaling mechanisms. Molecular Nutrition & Food Research, 52, 53-61.
17. Berger J, Moller DE. (2002) The mechanisms of action of PPARs. Annual Review of Medicine, 53, 409-435.
18. Bellinger DA, Merricks EP, Nichols TC. (2006) Swine models of type 2 diabetes mellitus: insulin resistance, glucose tolerance, and cardiovascular complications. ILAR Journal, 47, 243-258.
19. Leclercq-Meyer V, Marchand J, Woussen-Colle MC, Giroix MH, Malaisse WJ. (1985) Multiple effects of leucine on glucagon, insulin, and somatostatin secretion from the perfused rat pancreas. Endocrinology, 116, 1168-1174.
20. Alam MA, Kauter K, Brown L. (2013) Naringin improves diet-induced cardiovascular dysfunction and obesity in high carbohydrate, high fat diet-fed rats. Nutrients, 5, 637-650.
21. Oner-Iyidogan Y, Kocak H, Seyidhanoglu M, Gurdol F, Gulcubuk A, Yildirim F, Cevik A, Uysal M. (2013) Curcumin prevents liver fat accumulation and serum fetuin-A increase in rats fed a high-fat diet. Journal of Physiology and Biochemistry, 69, 677-686.
22. Karthikesan K, Pari L, Menon VP. (2010) Antihyperlipidemic effect of chlorogenic acid and tetrahydrocurcumin in rats subjected to diabetogenic agents. Chemico-Biological Interactions, 188, 643-650.
23. Huang K, Liang XC, Zhong YL, He WY, Wang Z. (2015) 5-Caffeoylquinic acid decreases diet-induced obesity in rats by modulating PPARalpha and LXRalpha transcription. Journal of the Science of Food and Agriculture, 1903-1910.
24. Torres-Leal FL, Fonseca-Alaniz MH, Teodoro GF, de Capitani MD, Vianna D, Pantaleao LC, Matos-Neto EM, Rogero MM, Donato J, Jr., Tirapegui J. (2011) Leucine supplementation improves adiponectin and total cholesterol concentrations despite the lack of changes in adiposity or glucose homeostasis in rats previously exposed to a high-fat diet. Nutrition & Metabolism, 8, 62. Doi: 10.1186/1743-7075-8-62.
25. Tai MM. (1994) A mathematical model for the determination of total area under glucose tolerance and other metabolic curves. Diabetes Care, 17, 152-154.
26. Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC. (1985) Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia, 28, 412-419.