Antitumor activity of the multikinase inhibitor regorafenib in patient-derived xenograft models of gastric cancer

Journal of Experimental and Clinical Cancer Research

Volumn 34, Issue 1, 2015, Pages

  Huynh, Hung ^a   Ong, Richard ^a   Zopf, Dieter ^b  

^a DIVISION OF MEDICAL ONCOLOGY   (Singapore)

^b BAYER PHARMA AG   (Germany)

Author keywords

Angiogenesis; Antitumor; Gastric cancer; Patient derived xenograft models; Regorafenib

Indexed keywords

REGORAFENIB; ANGIOGENESIS INHIBITOR; ANTINEOPLASTIC AGENT; CARBANILAMIDE DERIVATIVE; PROTEIN KINASE INHIBITOR; PYRIDINE DERIVATIVE;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL PROLIFERATION; CONTROLLED STUDY; DRUG EFFICACY; DRUG TOLERABILITY; HUMAN; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; STOMACH CANCER; TREATMENT RESPONSE; TUMOR VOLUME; ANIMAL; DISEASE MODEL; DOSE RESPONSE; DRUG EFFECTS; DRUG SCREENING; NEOVASCULARIZATION, PATHOLOGIC; PATHOLOGY; STOMACH NEOPLASMS; TUMOR CELL LINE;

ANGIOGENESIS INHIBITORS; ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL LINE, TUMOR; CELL PROLIFERATION; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; MICE; NEOVASCULARIZATION, PATHOLOGIC; PHENYLUREA COMPOUNDS; PROTEIN KINASE INHIBITORS; PYRIDINES; STOMACH NEOPLASMS; TUMOR BURDEN; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84945979680     PISSN: None     EISSN: 17569966     Source Type: Journal    
DOI: 10.1186/s13046-015-0243-5     Document Type: Article

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