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Volumn 46, Issue 11, 2015, Pages 3194-3201

Effect of Hyperacute Administration (Within 6 Hours) of Transdermal Glyceryl Trinitrate, a Nitric Oxide Donor, on Outcome after Stroke: Subgroup Analysis of the Efficacy of Nitric Oxide in Stroke (ENOS) Trial

Author keywords

blood pressure; cerebral hemorrhage; nitric oxide; nitroglycerin; stroke

Indexed keywords

ALTEPLASE; ANTIHYPERTENSIVE AGENT; GLYCERYL TRINITRATE; NITRIC ACID DERIVATIVE; NITRIC OXIDE DONOR; VASODILATOR AGENT;

EID: 84945968190     PISSN: 00392499     EISSN: 15244628     Source Type: Journal    
DOI: 10.1161/STROKEAHA.115.009647     Document Type: Article
Times cited : (85)

References (43)
  • 1
    • 0034074730 scopus 로고    scopus 로고
    • Indications for early aspirin use in acute ischemic stroke: A combined analysis of 40 000 randomized patients from the Chinese acute stroke trial and the international stroke trial. on behalf of the CAST and IST collaborative groups
    • Chen ZM, Sandercock P, Pan HC, Counsell C, Collins R, Liu LS, Indications for early aspirin use in acute ischemic stroke: a combined analysis of 40 000 randomized patients from the chinese acute stroke trial and the international stroke trial. On behalf of the CAST and IST collaborative groups. Stroke 2000 31 1240 1249
    • (2000) Stroke , vol.31 , pp. 1240-1249
    • Chen, Z.M.1    Sandercock, P.2    Pan, H.C.3    Counsell, C.4    Collins, R.5    Liu, L.S.6
  • 2
    • 33846892907 scopus 로고    scopus 로고
    • Early decompressive surgery in malignant infarction of the middle cerebral artery: A pooled analysis of three randomised controlled trials
    • Vahedi K, Hofmeijer J, Juettler E, Vicaut E, George B, Algra A, DECIMAL, DESTINY, and HAMLET investigators Early decompressive surgery in malignant infarction of the middle cerebral artery: a pooled analysis of three randomised controlled trials. Lancet Neurol 2007 6 215 222. doi: 10.1016/S1474-4422(07)70036-4
    • (2007) Lancet Neurol , vol.6 , pp. 215-222
    • Vahedi, K.1    Hofmeijer, J.2    Juettler, E.3    Vicaut, E.4    George, B.5    Algra, A.6
  • 3
    • 34548144563 scopus 로고    scopus 로고
    • Organised inpatient (stroke unit) care for stroke
    • Stroke Unit Trialists' Collaboration Organised inpatient (stroke unit) care for stroke. Cochrane Database Syst Rev. 2014 9 CD000197
    • (2014) Cochrane Database Syst Rev. , vol.9 , pp. CD000197
  • 7
    • 84924691962 scopus 로고    scopus 로고
    • Randomized assessment of rapid endovascular treatment of ischemic stroke
    • Goyal M, Demchuk AM, Menon BK, Eesa M, Rempel JL, Thornton J, ESCAPE Trial Investigators Randomized assessment of rapid endovascular treatment of ischemic stroke. N Engl J Med 2015 372 1019 1030. doi: 10.1056/NEJMoa1414905
    • (2015) N Engl J Med , vol.372 , pp. 1019-1030
    • Goyal, M.1    Demchuk, A.M.2    Menon, B.K.3    Eesa, M.4    Rempel, J.L.5    Thornton, J.6
  • 8
    • 84879082528 scopus 로고    scopus 로고
    • Rapid blood-pressure lowering in patients with acute intracerebral hemorrhage
    • Anderson CS, Heeley E, Huang Y, Wang J, Stapf C, Delcourt C, INTERACT2 Investigators Rapid blood-pressure lowering in patients with acute intracerebral hemorrhage. N Engl J Med 2013 368 2355 2365. doi: 10.1056/NEJMoa1214609
    • (2013) N Engl J Med , vol.368 , pp. 2355-2365
    • Anderson, C.S.1    Heeley, E.2    Huang, Y.3    Wang, J.4    Stapf, C.5    Delcourt, C.6
  • 9
    • 0037340783 scopus 로고    scopus 로고
    • The potential of nitric oxide therapeutics in stroke
    • Willmot MR, Bath PM, The potential of nitric oxide therapeutics in stroke. Expert Opin Investig Drugs 2003 12 455 470. doi: 10.1517/13543784.12.3.455
    • (2003) Expert Opin Investig Drugs , vol.12 , pp. 455-470
    • Willmot, M.R.1    Bath, P.M.2
  • 10
    • 84859921204 scopus 로고    scopus 로고
    • Current therapeutic strategies to mitigate the eNOS dysfunction in ischaemic stroke
    • Srivastava K, Bath PM, Bayraktutan U, Current therapeutic strategies to mitigate the eNOS dysfunction in ischaemic stroke. Cell Mol Neurobiol 2012 32 319 336. doi: 10.1007/s10571-011-9777-z
    • (2012) Cell Mol Neurobiol , vol.32 , pp. 319-336
    • Srivastava, K.1    Bath, P.M.2    Bayraktutan, U.3
  • 11
    • 84910599922 scopus 로고    scopus 로고
    • The role of the nitric oxide pathway in brain injury and its treatment-from bench to bedside
    • Garry PS, Ezra M, Rowland MJ, Westbrook J, Pattinson KT, The role of the nitric oxide pathway in brain injury and its treatment-from bench to bedside. Exp Neurol 2015 263 235 243. doi: 10.1016/j.expneurol.2014.10.017
    • (2015) Exp Neurol , vol.263 , pp. 235-243
    • Garry, P.S.1    Ezra, M.2    Rowland, M.J.3    Westbrook, J.4    Pattinson, K.T.5
  • 12
    • 15944376243 scopus 로고    scopus 로고
    • A systematic review of nitric oxide donors and L-arginine in experimental stroke; Effects on infarct size and cerebral blood flow
    • Willmot M, Gray L, Gibson C, Murphy S, Bath PM, A systematic review of nitric oxide donors and L-arginine in experimental stroke; effects on infarct size and cerebral blood flow. Nitric Oxide 2005 12 141 149. doi: 10.1016/j.niox.2005.01.003
    • (2005) Nitric Oxide , vol.12 , pp. 141-149
    • Willmot, M.1    Gray, L.2    Gibson, C.3    Murphy, S.4    Bath, P.M.5
  • 13
    • 0031922540 scopus 로고    scopus 로고
    • Pathophysiological assessment of nitric oxide (given as sodium nitroprusside) in acute ischaemic stroke
    • Butterworth RJ, Cluckie A, Jackson SH, Buxton-Thomas M, Bath PM, Pathophysiological assessment of nitric oxide (given as sodium nitroprusside) in acute ischaemic stroke. Cerebrovasc Dis 1998 8 158 165
    • (1998) Cerebrovasc Dis , vol.8 , pp. 158-165
    • Butterworth, R.J.1    Cluckie, A.2    Jackson, S.H.3    Buxton-Thomas, M.4    Bath, P.M.5
  • 14
    • 0035052592 scopus 로고    scopus 로고
    • The effect of transdermal glyceryl trinitrate, a nitric oxide donor, on blood pressure and platelet function in acute stroke
    • Bath PM, Pathansali R, Iddenden R, Bath FJ, The effect of transdermal glyceryl trinitrate, a nitric oxide donor, on blood pressure and platelet function in acute stroke. Cerebrovasc Dis 2001 11 265 272. doi: 10.1159/000047649.
    • (2001) Cerebrovasc Dis , vol.11 , pp. 265-272
    • Bath, P.M.1    Pathansali, R.2    Iddenden, R.3    Bath, F.J.4
  • 15
    • 0038165102 scopus 로고    scopus 로고
    • The effects of transdermal glyceryl trinitrate, a nitric oxide donor, on blood pressure, cerebral and cardiac hemodynamics, and plasma nitric oxide levels in acute stroke
    • Rashid P, Weaver C, Leonardi-Bee J, Bath F, Fletcher S, Bath P, The effects of transdermal glyceryl trinitrate, a nitric oxide donor, on blood pressure, cerebral and cardiac hemodynamics, and plasma nitric oxide levels in acute stroke. J Stroke Cerebrovasc Dis 2003 12 143 151. doi: 10.1016/S1052-3057(03)00037-5
    • (2003) J Stroke Cerebrovasc Dis , vol.12 , pp. 143-151
    • Rashid, P.1    Weaver, C.2    Leonardi-Bee, J.3    Bath, F.4    Fletcher, S.5    Bath, P.6
  • 16
    • 33744970068 scopus 로고    scopus 로고
    • Transdermal glyceryl trinitrate lowers blood pressure and maintains cerebral blood flow in recent stroke
    • Willmot M, Ghadami A, Whysall B, Clarke W, Wardlaw J, Bath PM, Transdermal glyceryl trinitrate lowers blood pressure and maintains cerebral blood flow in recent stroke. Hypertension 2006 47 1209 1215. doi: 10.1161/01.HYP.0000223024.02939.1e
    • (2006) Hypertension , vol.47 , pp. 1209-1215
    • Willmot, M.1    Ghadami, A.2    Whysall, B.3    Clarke, W.4    Wardlaw, J.5    Bath, P.M.6
  • 17
    • 84888257544 scopus 로고    scopus 로고
    • Feasibility of an ambulance-based stroke trial, and safety of glyceryl trinitrate in ultra-acute stroke: The rapid intervention with glyceryl trinitrate in Hypertensive Stroke Trial (RIGHT, ISRCTN66434824)
    • Ankolekar S, Fuller M, Cross I, Renton C, Cox P, Sprigg N, Feasibility of an ambulance-based stroke trial, and safety of glyceryl trinitrate in ultra-acute stroke: the rapid intervention with glyceryl trinitrate in Hypertensive Stroke Trial (RIGHT, ISRCTN66434824). Stroke 2013 44 3120 3128. doi: 10.1161/STROKEAHA.113.001301
    • (2013) Stroke , vol.44 , pp. 3120-3128
    • Ankolekar, S.1    Fuller, M.2    Cross, I.3    Renton, C.4    Cox, P.5    Sprigg, N.6
  • 18
    • 84923035699 scopus 로고    scopus 로고
    • Efficacy of nitric oxide, with or without continuing antihypertensive treatment, for management of high blood pressure in acute stroke (ENOS): A partial-factorial randomised controlled trial
    • Bath P, Woodhouse L, Scutt P, Krishnan K, Wardlaw J, Bereczki D, Efficacy of nitric oxide, with or without continuing antihypertensive treatment, for management of high blood pressure in acute stroke (ENOS): a partial-factorial randomised controlled trial. Lancet 2015 385 617 628
    • (2015) Lancet , vol.385 , pp. 617-628
    • Bath, P.1    Woodhouse, L.2    Scutt, P.3    Krishnan, K.4    Wardlaw, J.5    Bereczki, D.6
  • 19
    • 84896316561 scopus 로고    scopus 로고
    • Statistical analysis plan for the 'Efficacy of Nitric Oxide in Stroke' (ENOS) trial
    • Bath PM, Houlton A, Woodhouse L, Sprigg N, Wardlaw J, Pocock S, ENOS Trialists Statistical analysis plan for the 'Efficacy of Nitric Oxide in Stroke' (ENOS) trial. Int J Stroke 2014 9 372 374. doi: 10.1111/ijs.12235
    • (2014) Int J Stroke , vol.9 , pp. 372-374
    • Bath, P.M.1    Houlton, A.2    Woodhouse, L.3    Sprigg, N.4    Wardlaw, J.5    Pocock, S.6
  • 20
    • 33749621388 scopus 로고    scopus 로고
    • Glyceryl trinitrate vs. Control, and continuing vs. Stopping temporarily prior antihypertensive therapy, in acute stroke: Rationale and design of the efficacy of nitric oxide in stroke (ENOS) trial (isrctn99414122)
    • The ENOS Trial Investigators Glyceryl trinitrate vs. control, and continuing vs. stopping temporarily prior antihypertensive therapy, in acute stroke: rationale and design of the efficacy of nitric oxide in stroke (ENOS) trial (isrctn99414122). Int J Stroke 2006 1 245 249
    • (2006) Int J Stroke , vol.1 , pp. 245-249
  • 21
    • 84904697747 scopus 로고    scopus 로고
    • Baseline characteristics of the 4011 patients recruited into the "efficacy of nitric oxide in stroke" (enos) trial
    • ENOS Investigators Baseline characteristics of the 4011 patients recruited into the "efficacy of nitric oxide in stroke" (enos) trial. Int J Stroke 2014 9 711 720
    • (2014) Int J Stroke , vol.9 , pp. 711-720
  • 22
    • 84859433324 scopus 로고    scopus 로고
    • Contemporary outcome measures in acute stroke research: Choice of primary outcome measure
    • Lees KR, Bath PM, Schellinger PD, Kerr DM, Fulton R, Hacke W, European Stroke Organization Outcomes Working Group Contemporary outcome measures in acute stroke research: choice of primary outcome measure. Stroke 2012 43 1163 1170. doi: 10.1161/STROKEAHA.111.641423
    • (2012) Stroke , vol.43 , pp. 1163-1170
    • Lees, K.R.1    Bath, P.M.2    Schellinger, P.D.3    Kerr, D.M.4    Fulton, R.5    Hacke, W.6
  • 23
    • 70350717090 scopus 로고    scopus 로고
    • Interconversion of the National Institutes of Health Stroke Scale and Scandinavian Stroke Scale in acute stroke
    • Gray LJ, Ali M, Lyden PD, Bath PM, Virtual International Stroke Trials Archive Collaboration Interconversion of the National Institutes of Health Stroke Scale and Scandinavian Stroke Scale in acute stroke. J Stroke Cerebrovasc Dis 2009 18 466 468. doi: 10.1016/j.jstrokecerebrovasdis.2009.02.003
    • (2009) J Stroke Cerebrovasc Dis , vol.18 , pp. 466-468
    • Gray, L.J.1    Ali, M.2    Lyden, P.D.3    Bath, P.M.4
  • 24
    • 76549189227 scopus 로고
    • A self-rating depression scale
    • Zung WW, A SELF-RATING DEPRESSION SCALE. Arch Gen Psychiatry 1965 12 63 70
    • (1965) Arch Gen Psychiatry , vol.12 , pp. 63-70
    • Zung, W.W.1
  • 25
    • 51349157097 scopus 로고    scopus 로고
    • A randomised controlled trial of triple antiplatelet therapy (aspirin, clopidogrel and dipyridamole) in the secondary prevention of stroke: Safety, tolerability and feasibility
    • Sprigg N, Gray LJ, England T, Willmot MR, Zhao L, Sare GM, A randomised controlled trial of triple antiplatelet therapy (aspirin, clopidogrel and dipyridamole) in the secondary prevention of stroke: safety, tolerability and feasibility. PLoS One 2008 3 e2852. doi: 10.1371/journal.pone.0002852
    • (2008) PLoS One , vol.3 , pp. e2852
    • Sprigg, N.1    Gray, L.J.2    England, T.3    Willmot, M.R.4    Zhao, L.5    Sare, G.M.6
  • 26
    • 84905593948 scopus 로고    scopus 로고
    • Relationship between poststroke cognition, baseline factors, and functional outcome: Data from "efficacy of nitric oxide in stroke" trial
    • Ankolekar S, Renton C, Sare G, Ellender S, Sprigg N, Wardlaw JM, ENOS Trial Investigators Relationship between poststroke cognition, baseline factors, and functional outcome: data from "efficacy of nitric oxide in stroke" trial. J Stroke Cerebrovasc Dis 2014 23 1821 1829. doi: 10.1016/j.jstrokecerebrovasdis.2014.04.022
    • (2014) J Stroke Cerebrovasc Dis , vol.23 , pp. 1821-1829
    • Ankolekar, S.1    Renton, C.2    Sare, G.3    Ellender, S.4    Sprigg, N.5    Wardlaw, J.M.6
  • 27
    • 82255192780 scopus 로고    scopus 로고
    • Calculation of numbers-needed-to-treat in parallel group trials assessing ordinal outcomes: Case examples from acute stroke and stroke prevention
    • Bath P, Hogg C, Tracy M, Pocock S, Calculation of numbers-needed-to-treat in parallel group trials assessing ordinal outcomes: Case examples from acute stroke and stroke prevention. Int J Stroke 2011 6 472 479
    • (2011) Int J Stroke , vol.6 , pp. 472-479
    • Bath, P.1    Hogg, C.2    Tracy, M.3    Pocock, S.4
  • 28
    • 0025739901 scopus 로고
    • Classification and natural history of clinically identifiable subtypes of cerebral infarction
    • Bamford J, Sandercock P, Dennis M, Burn J, Warlow C, Classification and natural history of clinically identifiable subtypes of cerebral infarction. Lancet 1991 337 1521 1526
    • (1991) Lancet , vol.337 , pp. 1521-1526
    • Bamford, J.1    Sandercock, P.2    Dennis, M.3    Burn, J.4    Warlow, C.5
  • 29
    • 84869047736 scopus 로고    scopus 로고
    • Determining the feasibility of ambulance-based randomised controlled trials in patients with ultra-acute stroke: Study protocol for the "rapid Intervention with GTN in Hypertensive Stroke Trial" (RIGHT, ISRCTN66434824)
    • Ankolekar S, Sare G, Geeganage C, Fuller M, Stokes L, Sprigg N, Determining the feasibility of ambulance-based randomised controlled trials in patients with ultra-acute stroke: study protocol for the "Rapid Intervention with GTN in Hypertensive Stroke Trial" (RIGHT, ISRCTN66434824). Stroke Res Treat 2012 2012 385753. doi: 10.1155/2012/385753
    • (2012) Stroke Res Treat , vol.2012 , pp. 385753
    • Ankolekar, S.1    Sare, G.2    Geeganage, C.3    Fuller, M.4    Stokes, L.5    Sprigg, N.6
  • 30
    • 0036093482 scopus 로고    scopus 로고
    • Blood pressure and clinical outcomes in the International Stroke Trial
    • Leonardi-Bee J, Bath PM, Phillips SJ, Sandercock PA, IST Collaborative Group Blood pressure and clinical outcomes in the International Stroke Trial. Stroke 2002 33 1315 1320
    • (2002) Stroke , vol.33 , pp. 1315-1320
    • Leonardi-Bee, J.1    Bath, P.M.2    Phillips, S.J.3    Sandercock, P.A.4
  • 31
    • 84920278321 scopus 로고    scopus 로고
    • Blood pressure-lowering treatment with candesartan in patients with acute hemorrhagic stroke
    • Jusufovic M, Sandset EC, Bath PM, Berge E, Scandinavian Candesartan Acute Stroke Trial Study Group Blood pressure-lowering treatment with candesartan in patients with acute hemorrhagic stroke. Stroke 2014 45 3440 3442. doi: 10.1161/STROKEAHA.114.006433
    • (2014) Stroke , vol.45 , pp. 3440-3442
    • Jusufovic, M.1    Sandset, E.C.2    Bath, P.M.3    Berge, E.4
  • 33
    • 2942700683 scopus 로고    scopus 로고
    • Magnesium for acute stroke (Intravenous Magnesium Efficacy in Stroke trial): Randomised controlled trial
    • Muir KW, Lees KR, Ford I, Davis S, Intravenous Magnesium Efficacy in Stroke (IMAGES) Study Investigators Magnesium for acute stroke (Intravenous Magnesium Efficacy in Stroke trial): randomised controlled trial. Lancet 2004 363 439 445. doi: 10.1016/S0140-6736(04)15490-1
    • (2004) Lancet , vol.363 , pp. 439-445
    • Muir, K.W.1    Lees, K.R.2    Ford, I.3    Davis, S.4
  • 34
    • 84893596863 scopus 로고    scopus 로고
    • Effects of immediate blood pressure reduction on death and major disability in patients with acute ischemic stroke: The CATIS randomized clinical trial
    • He J, Zhang Y, Xu T, Zhao Q, Wang D, Chen CS, CATIS Investigators Effects of immediate blood pressure reduction on death and major disability in patients with acute ischemic stroke: the CATIS randomized clinical trial. JAMA 2014 311 479 489. doi: 10.1001/jama.2013.282543
    • (2014) JAMA , vol.311 , pp. 479-489
    • He, J.1    Zhang, Y.2    Xu, T.3    Zhao, Q.4    Wang, D.5    Chen, C.S.6
  • 35
    • 0026460295 scopus 로고
    • L-arginine dilates rat pial arterioles by nitric oxide-dependent mechanisms and increases blood flow during focal cerebral ischaemia
    • Morikawa E, Rosenblatt S, Moskowitz MA, L-arginine dilates rat pial arterioles by nitric oxide-dependent mechanisms and increases blood flow during focal cerebral ischaemia. Br J Pharmacol 1992 107 905 907
    • (1992) Br J Pharmacol , vol.107 , pp. 905-907
    • Morikawa, E.1    Rosenblatt, S.2    Moskowitz, M.A.3
  • 36
    • 0344520206 scopus 로고    scopus 로고
    • Plasma nitric oxide (nitrate/nitrite) levels in acute stroke and their relationship with severity and outcome
    • Rashid PA, Whitehurst A, Lawson N, Bath PM, Plasma nitric oxide (nitrate/nitrite) levels in acute stroke and their relationship with severity and outcome. J Stroke Cerebrovasc Dis 2003 12 82 87. doi: 10.1053/jscd.2003.9
    • (2003) J Stroke Cerebrovasc Dis , vol.12 , pp. 82-87
    • Rashid, P.A.1    Whitehurst, A.2    Lawson, N.3    Bath, P.M.4
  • 37
    • 0032019514 scopus 로고    scopus 로고
    • Nitric oxide plasma levels in patients with chronic and acute cerebrovascular disorders
    • Ferlito S, Gallina M, Pitari GM, Bianchi A, Nitric oxide plasma levels in patients with chronic and acute cerebrovascular disorders. Panminerva Med 1998 40 51 54
    • (1998) Panminerva Med , vol.40 , pp. 51-54
    • Ferlito, S.1    Gallina, M.2    Pitari, G.M.3    Bianchi, A.4
  • 38
    • 0032953495 scopus 로고    scopus 로고
    • Clomethiazole acute stroke study (CLASS): Results of a randomized, controlled trial of clomethiazole versus placebo in 1360 acute stroke patients
    • Wahlgren NG, Ranasinha KW, Rosolacci T, Franke CL, van Erven PM, Ashwood T, Clomethiazole acute stroke study (CLASS): results of a randomized, controlled trial of clomethiazole versus placebo in 1360 acute stroke patients. Stroke 1999 30 21 28
    • (1999) Stroke , vol.30 , pp. 21-28
    • Wahlgren, N.G.1    Ranasinha, K.W.2    Rosolacci, T.3    Franke, C.L.4    Van Erven, P.M.5    Ashwood, T.6
  • 39
    • 0036968150 scopus 로고    scopus 로고
    • Fiblast (trafermin) in acute stroke: Results of the European-Australian phase II/III safety and efficacy trial
    • Bogousslavsky J, Victor SJ, Salinas EO, Pallay A, Donnan GA, Fieschi C, European-Australian Fiblast (Trafermin) in Acute Stroke Group Fiblast (trafermin) in acute stroke: results of the European-Australian phase II/III safety and efficacy trial. Cerebrovasc Dis 2002 14 239 251. doi: 10.1159/000065683.
    • (2002) Cerebrovasc Dis , vol.14 , pp. 239-251
    • Bogousslavsky, J.1    Victor, S.J.2    Salinas, E.O.3    Pallay, A.4    Donnan, G.A.5    Fieschi, C.6
  • 40
    • 13144256723 scopus 로고    scopus 로고
    • Early surgery versus initial conservative treatment in patients with spontaneous supratentorial intracerebral haematomas in the International Surgical Trial in Intracerebral Haemorrhage (STICH): A randomised trial
    • Mendelow AD, Gregson BA, Fernandes HM, Murray GD, Teasdale GM, Hope DT, STICH investigators Early surgery versus initial conservative treatment in patients with spontaneous supratentorial intracerebral haematomas in the International Surgical Trial in Intracerebral Haemorrhage (STICH): a randomised trial. Lancet 2005 365 387 397. doi: 10.1016/S0140-6736(05)17826-X
    • (2005) Lancet , vol.365 , pp. 387-397
    • Mendelow, A.D.1    Gregson, B.A.2    Fernandes, H.M.3    Murray, G.D.4    Teasdale, G.M.5    Hope, D.T.6
  • 41
    • 84881164520 scopus 로고    scopus 로고
    • Early surgery versus initial conservative treatment in patients with spontaneous supratentorial lobar intracerebral haematomas (STICH II): A randomised trial
    • Mendelow AD, Gregson BA, Rowan EN, Murray GD, Gholkar A, Mitchell PM, STICH II Investigators Early surgery versus initial conservative treatment in patients with spontaneous supratentorial lobar intracerebral haematomas (STICH II): a randomised trial. Lancet 2013 382 397 408. doi: 10.1016/S0140-6736(13)60986-1
    • (2013) Lancet , vol.382 , pp. 397-408
    • Mendelow, A.D.1    Gregson, B.A.2    Rowan, E.N.3    Murray, G.D.4    Gholkar, A.5    Mitchell, P.M.6
  • 42
    • 84912028897 scopus 로고    scopus 로고
    • Paramedic Initiated Lisinopril for Acute Stroke Treatment (PIL-FAST): Results from the pilot randomised controlled trial
    • Shaw L, Price C, McLure S, Howel D, McColl E, Younger P, Paramedic Initiated Lisinopril For Acute Stroke Treatment (PIL-FAST): results from the pilot randomised controlled trial. Emerg Med J 2014 31 994 999. doi: 10.1136/emermed-2013-202536
    • (2014) Emerg Med J , vol.31 , pp. 994-999
    • Shaw, L.1    Price, C.2    McLure, S.3    Howel, D.4    McColl, E.5    Younger, P.6
  • 43
    • 84922309595 scopus 로고    scopus 로고
    • Prehospital use of magnesium sulfate as neuroprotection in acute stroke
    • Saver JL, Starkman S, Eckstein M, Stratton SJ, Pratt FD, Hamilton S, FAST-MAG Investigators and Coordinators Prehospital use of magnesium sulfate as neuroprotection in acute stroke. N Engl J Med 2015 372 528 536. doi: 10.1056/NEJMoa1408827
    • (2015) N Engl J Med , vol.372 , pp. 528-536
    • Saver, J.L.1    Starkman, S.2    Eckstein, M.3    Stratton, S.J.4    Pratt, F.D.5    Hamilton, S.6


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