High prevalence and clinical relevance of genes affected by chromosomal breaks in colorectal cancer

PLoS ONE

Volumn 10, Issue 9, 2015, Pages

  Van Den Broek, Evert ^a,d   Dijkstra, Maurits J J ^b   Krijgsman, Oscar ^a,d   Sie, Daoud ^a   Haan, Josien C ^a   Traets, Joleen J H ^a   Van De Wiel, Mark A ^a,b   Nagtegaal, Iris D ^c   Punt, Cornelis J A ^a   Carvalho, Beatriz ^a,d   Ylstra, Bauke ^a   Abeln, Sanne ^b   Meijer, Gerrit A ^a,d   Fijneman, Remond J A ^a,d  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

^b VU UNIVERSITY AMSTERDAM   (Netherlands)

^c RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^d NETHERLANDS CANCER INSTITUTE   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

APC PROTEIN; B RAF KINASE; K RAS PROTEIN; PROTEIN P53; SMAD4 PROTEIN; TUMOR MARKER;

APC GENE; ARTICLE; BRAF GENE; CANCER TISSUE; CARCINOGENESIS; CHROMOSOME BREAKAGE; COLORECTAL CANCER; COMPARATIVE GENOMIC HYBRIDIZATION; FBXW7 GENE; GENE DOSAGE; GENE IDENTIFICATION; GENE MUTATION; GENE SEQUENCE; GENETIC ASSOCIATION; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; METASTASIS; ONCOGENE; ONCOGENE K RAS; ONCOGENE N RAS; PHASE 2 CLINICAL TRIAL (TOPIC); PIK3CA GENE; POINT MUTATION; PREVALENCE; SMAD4 GENE; TP53 GENE; COLORECTAL TUMOR; GENETICS; GENOME-WIDE ASSOCIATION STUDY; MULTICENTER STUDY (TOPIC); MUTATION; PATHOLOGY; PHASE 3 CLINICAL TRIAL (TOPIC); PROGNOSIS; RANDOMIZED CONTROLLED TRIAL (TOPIC);

BIOMARKERS, TUMOR; CHROMOSOME BREAKAGE; CLINICAL TRIALS, PHASE III AS TOPIC; COLORECTAL NEOPLASMS; GENOME-WIDE ASSOCIATION STUDY; HUMANS; MULTICENTER STUDIES AS TOPIC; MUTATION; PROGNOSIS; RANDOMIZED CONTROLLED TRIALS AS TOPIC;

EID: 84945923549     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0138141     Document Type: Article

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