Induction of FGF-2 synthesis by IL-1β in aqueous Humor through P13-kinase and p38 in rabbit corneal endothelium

Investigative Ophthalmology and Visual Science

Volumn 51, Issue 2, 2010, Pages 822-829

  Song, Jong Suk ^a,b   Lee, Jeong Goo ^a   Kay, Eun Duck P ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b Korea University College of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ACTIN; FIBROBLAST GROWTH FACTOR 2; INTERLEUKIN 1BETA; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN ANTIBODY; PROTEIN KINASE B; SYNAPTOPHYSIN; 2-(4-MORPHOLINYL)-8-PHENYL-4H-1-BENZOPYRAN-4-ONE; CHROMONE DERIVATIVE; ENZYME INHIBITOR; IMIDAZOLE DERIVATIVE; MITOGEN ACTIVATED PROTEIN KINASE P38; MORPHOLINE DERIVATIVE; PYRIDINE DERIVATIVE;

ANIMAL CELL; ANIMAL TISSUE; AQUEOUS HUMOR; ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CORNEA ENDOTHELIUM; CYTOSKELETON; ENZYME PHOSPHORYLATION; FREEZING; INFLAMMATION; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; RABBIT; UPREGULATION; WESTERN BLOTTING; ANIMAL; BIOSYNTHESIS; CORNEA OPACITY; CRYOSURGERY; DRUG EFFECT; FLUORESCENCE MICROSCOPY; FLUORESCENT ANTIBODY TECHNIQUE; METABOLISM; NEUTROPHIL; PATHOLOGY; PHOSPHORYLATION; PHYSIOLOGY; TIME;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ACTINS; ANIMALS; AQUEOUS HUMOR; BLOTTING, WESTERN; CHROMONES; CORNEAL OPACITY; CRYOSURGERY; ENDOTHELIUM, CORNEAL; ENZYME INHIBITORS; FIBROBLAST GROWTH FACTOR 2; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; IMIDAZOLES; INTERLEUKIN-1BETA; MICROSCOPY, FLUORESCENCE; MORPHOLINES; NEUTROPHIL INFILTRATION; NEUTROPHILS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PYRIDINES; RABBITS; TIME FACTORS; UP-REGULATION;

EID: 77449139250     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.09-4240     Document Type: Article

References (41)

1. Fuchs E. On keratoplasty. Z Augenheilkd. 1901;5:1-5.
2. Rodrigues MM, Waring GO, Laibson PR, Weinreb S. Endothelial alterations in congenital corneal dystrophies. Am J Ophthalmol. 1975;80:678-689.
3. Waring GO, Laibson PR, Rodrigues M. Clinical and pathologic alterations of Descemet's membrane: with emphasis on endothelial metaplasia. Surv Ophthalmol. 1974;18:325-331.
4. Sherrard ES, Rycroft PV. Retrocorneal membranes: their origin and structure. Br J Ophthalmol. 1967;51:379-386.
5. Kay EP, Smith RE, Nimni ME. Type I collagen synthesis by corneal endothelial cells modulated by polymorphonuclear leukocytes. J Biol Chem. 1985;260:5139-5149.
6. Kay EP, Gu X, Ninomiya Y, Smith RE. Corneal endothelial modulation: a factor released by leukocytes induces basic fibroblast growth factor that modulates cell shape and collagen. Invest Ophthalmol Vis Sci. 1993;34:663-672.
7. Kay EP, Gu X, Smith RE. Corneal endothelial modulation: bFGF as direct mediator and corneal endothelium modulation factor as inducer. Invest Ophthalmol Vis Sci. 1994;35:2427-2435.
8. Lee HT, Lee JG, Na M, Kay EP. FGF-2 induced by interleukin-1β through the action of phosphatidylinositol 3-kinase mediates endothelial mesenchymal transformation in corneal endothelial cells. J Biol Chem. 2004;279:32325-32332.
9. Dinarello CA. Biologic basis for interleukin-1 in disease. Blood. 1996;87:2095-2147.
10. Allan SM. The role of pro-and antiinflammatory cytokines in neurodegeneration. Ann N Y Acad Sci. 2000;917:84-93.
11. Gramantieri L, Casali A, Trerè D, et al. Imbalance of IL-1 beta and IL-1 receptor antagonist mRNA in liver tissue from hepatitis C virus (HCV)-related chronic hepatitis. Clin Exp Immunol. 1999;115:515-520.
12. Arend WP. The balance between IL-1 and IL-1Ra in disease. Cytokine Growth Factor Rev. 2002;13:323-340.
13. Cubitt CL, Lausch RN, Oakes JE. Synthesis of type II interleukin-1 receptors by human corneal epithelial cells but not by keratocytes. Invest Ophthalmol Vis Sci. 2001;42:701-704.
14. Moore JE, McMullen TCB, Campbell IL, et al. The inflammatory milieu associated with conjunctivalized cornea and its alteration with IL-1 RA gene therapy. Invest Ophthalmol Vis Sci. 2002;43: 2905-2915.
15. McDermott AM, Redfern RL, Zhang B, Pei Y, Huang L, Proske RJ. Defensin expression by the cornea: multiple signaling pathways mediate IL-1beta stimulation of hBD-2 expression by human corneal epithelial cells. Invest Ophthalmol Vis Sci. 2003;44:1859-1865.
16. Djalilan AR, Nagineni CN, Mahesh SP, Smith JA, Nussenblatt RB, Hooks JJ. Inhibition of inflammatory cytokine production in human corneal cells by dexamethasone, but not cyclosporin. Cornea. 2006;25:709-714.
17. Tamura M, Arakaki N, Tsubouchi H, Takada H, Daikuhara Y. Enhancement of human hepatocyte growth factor production by interleukin-1 alpha and-1 beta and tumor necrosis factor-alpha by fibroblasts in culture. J Biol Chem. 1993;268:8140-8145.
18. Pshenichkin SP, Szekely AM, Wise BC. Transcriptional and posttranscriptional mechanisms involved in the interleukin-1, steroid, and protein kinase C regulation of nerve growth factor in cortical astrocytes. J Neurochem. 1994;63:419-428.
19. Jung YD, Liu W, Reinmuth N, et al. Vascular endothelial growth factor is upregulated by interleukin-1β in human vascular smooth muscle cells via the p38 mitogen-activated protein kinase pathway. Angiogenesis. 2001;4:155-162.
20. Liu W, Reinmuth N, Stoeltzing O, et al. Cyclooxygenase-2 is upregulated by interleukin-1 beta in human colorectal cancer cells via multiple signaling pathways. Cancer Res. 2003;63:3632-3636.
21. Cronauer MV, Stadlmann S, Klocker H, et al. Basic fibroblast growth factor synthesis by human peritoneal mesothelial cells: induction by interleukin-1. Am J Pathol. 1999;155:1977-1984.
22. Sobue T, Zhang X, Florkiewicz RZ, Hurley MM. Interleukin-1 regulates FGF-2 mRNA and localization of FGF-2 protein in human osteoblasts. Biochem Biophys Res Commun. 2001;286:33-40.
23. Hayashi T, Matsuoka K, Saitoh M, Takeda S, Kimura M. Influence of α-tumor necrosis factor and β-interleukin-1 on production of angiogenetic factors and thymidine phosphorylase activity in immortalized human decidual fibroblasts in vitro. J Obstet Gynaecol Res. 2006;32:15-22.
24. Lee JG, Kay EP. Common and distinct pathways for cellular activities in FGF-2 signaling induced by IL-1β in corneal endothelial cells. Invest Ophthalmol Vis Sci. 2009;50:2067-2076.
25. Lee HT, Kay EP. Regulatory role of PI3-kinase on expression of Cdk 4 and p27, nuclear localization of Cdk4, and phosphorylation of p27 in corneal endothelial cells. Invest Ophthalmol Vis Sci. 2003; 44:1521-1528.
26. Lee JG, Kay EP. Two populations of p27 use differential kinetics to phosphorylate Ser-10 and Thr-187 via phosphatidylinositol 3-kinase in response to fibroblast growth factor-2 stimulation. J Biol Chem. 2007;282:6444-6454.
27. Lee JG, Kay EP. Involvement of two distinct ubiquitin E3 ligase systems for p27 degradation in corneal endothelial cells. Invest Ophthalmol Vis Sci. 2008;49:189-196.
28. Ko MK, Kay EP. Regulatory role of FGF-2 on type I collagen expression during endothelial mesenchymal transformation. Invest Ophthalmol Vis Sci. 2005;46:4495-4503.
29. Lee JG, Kay EP. Cross-talk among Rho GTPases acting downstream of PI3-kinase induces mesenchymal transformation of corneal endothelial cells mediated by FGF-2. Invest Ophthalmol Vis Sci. 2006;47:2358-2368.
30. Kay EP, Cheung CC, Jester JV, Nimni ME, Smith RE. Type I collagen and fibronectin synthesis by retrocorneal fibrous membrane. Invest Ophthalmol Vis Sci. 1982;22:200-212.
31. Choi J, Ko MK, Kay EP. Subcellular localization of the expressed 18 kDa FGF-2 isoform in corneal endothelial cells. Mol Vis. 2000;6: 222-231.
32. Lee JG, Kay EP. FGF-2-induced wound healing in corneal endothelial cells requires Cdc42 activation and Rho inactivation through the phosphatidylinositol 3-kinase pathway. Invest Ophthalmol Vis Sci. 2006;47:1376-1386.
33. Maumenee AE, Kornblueth W. Regeneration of the corneal stromal cells: technique for destruction of corneal corpuscles by application of solidified, frozen, carbon dioxide. Am J Ophthalmol. 1948; 31:699-702.
34. Jester JV, Rodrigues MM, Sun TT. Change in epithelial keratin expression during healing of rabbit corneal wounds. Invest Ophthalmol Vis Sci. 1985;26:828-837.
35. Saika S, Miyamoto T, Yamanaka O, et al. Therapeutic effect of topical administration of SN50, an inhibitor of nuclear factor-κB, in treatment of corneal alkali burns in mice. Am J Pathol. 2005;166: 1393-1403.
36. Saika S, Ikeda K, Yamanaka O, et al. Expression of Smad7 in mouse eyes accelerates healing of corneal tissue after exposure to alkali. Am J Pathol. 2005;166:1405-1418.
37. Sherif Z, Pleyer U. Corticosteroids in ophthalmology: past-presentfuture. Ophthalmologica. 2002;216:305-315.
38. Naumann GOH, Schlotzer-Schrehardt U. Keratopathy in pseudoexfoliation syndrome as a cause of corneal endothelial decompensation. Ophthalmology. 2000;107:1111-1124.
39. Kawaguchi R, Saika S, Wakayama M, et al. Extracellular matrix components in a case of retrocorneal membrane associated with syphilitic interstitial keratitis. Cornea. 2001;20:100-103.
40. Ichijima H, Petroll WM, Jester JV, et al. In vivo confocal microscopic studies of endothelial wound healing in rabbit cornea. Cornea. 1993;12:369-378.
41. Ichijima H, Petroll WM, Barry PA, et al. Actin filament organization during endothelial wound healing in the rabbit cornea: comparison between transcorneal freeze and mechanical scrape injuries. Invest Ophthalmol Vis Sci. 1993;34:2803-2812