Enhanced chemokine receptor recycling and impaired S1P1 expression promote leukemic cell infiltration of lymph nodes in chronic lymphocytic leukemia

Cancer Research

Volumn 75, Issue 19, 2015, Pages 4153-4163

  Patrussi, Laura ^a,b   Capitani, Nagaja ^a,b   Martini, Veronica ^c,d   Pizzi, Marco ^d   Trimarco, Valentina ^c,d   Frezzato, Federica ^c,d   Marino, Filippo ^d   Semenzato, Gianpietro ^c,d   Trentin, Livio ^c,d   Baldari, Cosima T ^a,b  

^a UNIVERSITY OF SIENA   (Italy)

^b ISTITUTO TOSCANO TUMORI   (Italy)

^c VENETIAN INSTITUTE OF MOLECULAR MEDICINE   (Italy)

^d UNIVERSITY OF PADOVA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CCR7; CHEMOKINE RECEPTOR CXCR4; IBRUTINIB; INTERCELLULAR ADHESION MOLECULE 1; RAB11 PROTEIN; SPHINGOSINE 1 PHOSPHATE; CCR7 PROTEIN, HUMAN; CXCR4 PROTEIN, HUMAN; HOMING RECEPTOR; MEMBRANE PROTEIN; MESSENGER RNA; RNA; S1PR1 PROTEIN, HUMAN; SPHINGOSINE 1 PHOSPHATE RECEPTOR; TUMOR PROTEIN;

ARTICLE; CELL ADHESION; CELL INFILTRATION; CELL MEMBRANE; CELL PROLIFERATION; CHRONIC LYMPHATIC LEUKEMIA; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFICACY; DRUG RESPONSE; DRUG TARGETING; ENDOSOME; HUMAN; HUMAN CELL; LEUKEMIA CELL; LYMPHOCYTOSIS; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; T LYMPHOCYTE; UPREGULATION; B LYMPHOCYTE; BIOSYNTHESIS; CHEMOTAXIS; DEFICIENCY; GENETICS; GERMINAL CENTER; LEUKEMIC INFILTRATION; LYMPH NODE; LYMPHOID TISSUE; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY;

B-LYMPHOCYTES; CHEMOTAXIS; ENDOSOMES; GERMINAL CENTER; HUMANS; LEUKEMIA, LYMPHOCYTIC, CHRONIC, B-CELL; LEUKEMIC INFILTRATION; LYMPH NODES; LYMPHOID TISSUE; MEMBRANE PROTEINS; NEOPLASM PROTEINS; RECEPTORS, CCR7; RECEPTORS, CXCR4; RECEPTORS, LYMPHOCYTE HOMING; RECEPTORS, LYSOSPHINGOLIPID; RNA, MESSENGER; RNA, NEOPLASM;

EID: 84945571425     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-15-0986     Document Type: Article

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