Honokiol inhibits melanoma stem cells by targeting notch signaling

Molecular Carcinogenesis

Volumn 54, Issue 12, 2015, Pages 1710-1721

  Kaushik, Gaurav ^a   Venugopal, Anand ^a   Ramamoorthy, Prabhu ^a,b   Standing, David ^a   Subramaniam, Dharmalingam ^a,b   Umar, Shahid ^a,b   Jensen, Roy A ^a,b   Anant, Shrikant ^a,b   Mammen, Joshua M V ^a,b  

^a UNIVERSITY OF KANSAS MEDICAL CENTER   (United States)

^b UNIVERSITY OF KANSAS CANCER CENTER   (United States)

Author keywords

Autophagy; Cancer stem cells; Cell cycle arrest; Notch 1; Notch 2

Indexed keywords

ABC TRANSPORTER B5; ACTIVATED LEUKOCYTE CELL ADHESION MOLECULE; BIOLOGICAL MARKER; CD271 ANTIGEN; CYCLIN D1; GAMMA SECRETASE; HONOKIOL; JARID1B PROTEIN; NICD1 PROTEIN; NICD2 PROTEIN; NOTCH RECEPTOR; NOTCH2 RECEPTOR; TRANSCRIPTION FACTOR HES 1; TUMOR NECROSIS FACTOR ALPHA CONVERTING ENZYME; UNCLASSIFIED DRUG; ADAM PROTEIN; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; BIPHENYL DERIVATIVE; HES1 PROTEIN, HUMAN; HOMEODOMAIN PROTEIN; LIGNAN; NOTCH2 PROTEIN, HUMAN; SECRETASE; TUMOR MARKER; TUMOR NECROSIS FACTOR-ALPHA CONVERTASE;

ANTIPROLIFERATIVE ACTIVITY; ARTICLE; AUTOPHAGY; CANCER STEM CELL; CELL NUCLEUS; CELL RENEWAL; CELL VIABILITY; CLONOGENESIS; CONTROLLED STUDY; DRUG POTENCY; DRUG TARGETING; ENZYME MECHANISM; GENE EXPRESSION; MELANOMA; MELANOMA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; WESTERN BLOTTING; CELL PROLIFERATION; CELL SURVIVAL; DRUG EFFECTS; HUMAN; METABOLISM; TUMOR CELL LINE;

ADAM PROTEINS; AMYLOID PRECURSOR PROTEIN SECRETASES; AUTOPHAGY; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; BIOMARKERS, TUMOR; BIPHENYL COMPOUNDS; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; CYCLIN D1; HOMEODOMAIN PROTEINS; HUMANS; LIGNANS; MELANOMA; NEOPLASTIC STEM CELLS; RECEPTOR, NOTCH2; RECEPTORS, NOTCH; SIGNAL TRANSDUCTION;

EID: 84945481325     PISSN: 08991987     EISSN: 10982744     Source Type: Journal    
DOI: 10.1002/mc.22242     Document Type: Article

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