Honokiol inhibits tumor necrosis factor-α-stimulated rat aortic smooth muscle cell proliferation via caspase- and mitochondrial-dependent apoptosis

Inflammation

Volumn 37, Issue 1, 2014, Pages 17-26

  Fan, Shuli ^a   Li, Xu ^a   Lin, Jie ^a   Chen, Sijiao ^a   Shan, Jinhua ^a   Qi, Guoxian ^a  

^a CHINA MEDICAL UNIVERSITY   (China)

Author keywords

apoptosis; caspase activation; honokiol; mitochondrial pathway; proliferation

Indexed keywords

CASPASE 3; CASPASE 9; CYCLIN D1; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE 4; CYCLIN E; CYTOCHROME C; HONOKIOL; LACTATE DEHYDROGENASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN BCL 2; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANTIPROLIFERATIVE ACTIVITY; AORTA; APOPTOSIS; ARTERY MUSCLE; ARTICLE; CARDIOVASCULAR DISEASE; CELL CYCLE REGULATION; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; CYTOSOL; CYTOTOXICITY TEST; DOWN REGULATION; DRUG MECHANISM; G1 PHASE CELL CYCLE CHECKPOINT; MALE; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; SMOOTH MUSCLE FIBER;

RATTUS;

ANIMALS; AORTA; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BIPHENYL COMPOUNDS; CASPASES; CELL PROLIFERATION; CELL SURVIVAL; CELLS, CULTURED; CYCLIN D1; CYCLIN E; CYCLIN-DEPENDENT KINASE 2; CYCLIN-DEPENDENT KINASE 4; CYTOCHROMES C; DRUGS, CHINESE HERBAL; ENZYME INHIBITORS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; G1 PHASE CELL CYCLE CHECKPOINTS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LIGNANS; MALE; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; MUSCLE, SMOOTH, VASCULAR; NITRIC OXIDE SYNTHASE; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84900361938     PISSN: 03603997     EISSN: 15732576     Source Type: Journal    
DOI: 10.1007/s10753-013-9707-y     Document Type: Article

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