Deficiency of HIF1α in Antigen-Presenting Cells Aggravates Atherosclerosis and Type 1 T-Helper Cell Responses in Mice

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 35, Issue 11, 2015, Pages 2316-2325

  Chaudhari, Sweena M ^a   Sluimer, Judith C ^d   Koch, Miriam ^a   Theelen, Thomas L ^d   Manthey, Helga D ^b   Busch, Martin ^b   Caballero Franco, Celia ^e   Vogel, Frederick ^f   Cochain, Clément ^a   Pelisek, Jaroslav ^g   Daemen, Mat J ^h   Lutz, Manfred B ^c   Görlach, Agnes ^f   Kissler, Stephan ^e   Hermanns, Heike M ^a,b   Zernecke, Alma ^a  

^a UNIVERSITY HOSPITAL WÜRZBURG   (Germany)

^b UNIVERSITY OF WÜRZBURG   (Germany)

^c Institute of Virology and Immunobiology   (Germany)

^d MAASTRICHT UNIVERSITY   (Netherlands)

^e HARVARD MEDICAL SCHOOL   (United States)

^f TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^g TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^h ACADEMIC MEDICAL CENTER   (Netherlands)

Author keywords

antigen presenting cells; atherosclerosis; diet; high fat; inflammation; leukocytes

Indexed keywords

CHOLESTEROL; GLYCOPROTEIN P 15095; HYPOXIA INDUCIBLE FACTOR 1ALPHA; INTERLEUKIN 12; MESSENGER RNA; OVALBUMIN; STAT3 PROTEIN; TUMOR NECROSIS FACTOR ALPHA; HIF1A PROTEIN, HUMAN; HIF1A PROTEIN, MOUSE; LOW DENSITY LIPOPROTEIN RECEPTOR; STAT3 PROTEIN, HUMAN; STAT3 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN PRESENTING CELL; AORTA ROOT; AORTIC TISSUE; ARTICLE; ATHEROGENESIS; ATHEROSCLEROSIS; ATHEROSCLEROTIC PLAQUE; B LYMPHOCYTE; BODY WEIGHT; BONE MARROW CELL; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL EXPANSION; CELL INFILTRATION; CELLULAR IMMUNITY; CHOLESTEROL BLOOD LEVEL; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; FLOW CYTOMETRY; GENOTYPE; HYPOXIA; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; LIPID DIET; LYMPHOCYTE DIFFERENTIATION; MACROPHAGE; MONOCYTE; MOUSE; NEUTROPHIL; NONHUMAN; ORGAN WEIGHT; POLARIZATION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; PROTEIN FUNCTION; T LYMPHOCYTE ACTIVATION; TH1 CELL; UPREGULATION; ANIMAL; AORTA; AORTA DISEASE; C57BL MOUSE; CAROTID ARTERY DISEASE; CELL CULTURE; COCULTURE; DEFICIENCY; DISEASE MODEL; GENETICS; HELPER CELL; HUMAN; IMMUNOLOGY; KNOCKOUT MOUSE; LYMPHOCYTE ACTIVATION; MALE; METABOLISM; PATHOLOGY; PHENOTYPE; SIGNAL TRANSDUCTION;

ANIMALS; ANTIGEN-PRESENTING CELLS; ANTIGENS, CD11C; AORTA; AORTIC DISEASES; ATHEROSCLEROSIS; CAROTID ARTERY DISEASES; CELLS, CULTURED; COCULTURE TECHNIQUES; DIET, HIGH-FAT; DISEASE MODELS, ANIMAL; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; INTERLEUKIN-12; LYMPHOCYTE ACTIVATION; MACROPHAGES; MALE; MICE, INBRED C57BL; MICE, KNOCKOUT; PHENOTYPE; PLAQUE, ATHEROSCLEROTIC; RECEPTORS, LDL; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; T-LYMPHOCYTES, HELPER-INDUCER;

EID: 84945477011     PISSN: 10795642     EISSN: 15244636     Source Type: Journal    
DOI: 10.1161/ATVBAHA.115.306171     Document Type: Article

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