Increased oxidative stress contributes to cardiomyocyte dysfunction and death in patients with Fabry disease cardiomyopathy

Human Pathology

Volumn 46, Issue 11, 2015, Pages 1760-1768

  Chimenti, Cristina ^a,b   Scopelliti, Fernanda ^a   Vulpis, Elisabetta ^b   Tafani, Marco ^a   Villanova, Lidia ^a   Verardo, Romina ^b   De Paulis, Ruggero ^c   Russo, Matteo A ^d   Frustaci, Andrea ^a,b  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b NATIONAL INSTITUTE FOR INFECTIOUS DISEASES L SPALLANZANI   (Italy)

^c EUROPEAN HOSPITAL   (Italy)

^d IRCCS SAN RAFFAELE PISANA   (Italy)

Author keywords

Cardiac dysfunction; Cardiomyopathy; Cell death; Fabry disease; Oxidative stress

Indexed keywords

3 NITROTYROSINE; 8 HYDROXYDEOXYGUANOSINE; DNA; INDUCIBLE NITRIC OXIDE SYNTHASE; 3-NITROTYROSINE; NITRIC OXIDE; TYROSINE;

ADULT; AGED; APOPTOSIS; ARTICLE; CARDIOMYOPATHY; CELL DEATH; CELL NUCLEUS; CLINICAL ARTICLE; CONTROLLED STUDY; DNA DAMAGE; ELECTRON MICROSCOPY; FABRY DISEASE; FEMALE; HEART MUSCLE BIOPSY; HEART MUSCLE CELL; HISTOPATHOLOGY; HUMAN; HYPERTROPHIC CARDIOMYOPATHY; IMMUNOHISTOCHEMISTRY; LIGATION; MALE; MIDDLE AGED; OXIDATIVE STRESS; PROTEIN ANALYSIS; PROTEIN EXPRESSION; WESTERN BLOTTING; ANALOGS AND DERIVATIVES; BIOSYNTHESIS; HEART MUSCLE; METABOLISM; MORTALITY; PATHOLOGY; PHYSIOLOGY;

ADULT; AGED; APOPTOSIS; FABRY DISEASE; FEMALE; HUMANS; MALE; MIDDLE AGED; MYOCARDIUM; MYOCYTES, CARDIAC; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; OXIDATIVE STRESS; TYROSINE;

EID: 84945476296     PISSN: 00468177     EISSN: 15328392     Source Type: Journal    
DOI: 10.1016/j.humpath.2015.07.017     Document Type: Article

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