Roles of ROS mediated oxidative stress and DNA damage in 3-methyl-2-quinoxalin benzenevinylketo-1, 4-dioxide-induced immunotoxicity of Sprague-Dawley rats

Regulatory Toxicology and Pharmacology

Volumn 73, Issue 2, 2014, Pages 587-594

  Gao, Hui ^a   Wang, Di ^a   Zhang, Shun ^a   Xu, Mengjing ^a   Yang, Wei ^a   Yan, Peipei ^a   Liu, Yang ^a   Luo, Xiao ^a   Wu, Hailei ^b   Yao, Ping ^a   Yan, Hong ^a   Liu, Liegang ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b Nanjing Exit Entry Inspection and Quarantine Bureau   (China)

Author keywords

3 methyl 2 quinoxalin benzenevinylketo 1; 4 dioxide; DNA damage; Immunotoxicity; Oxidative stress; Reactive oxygen species

Indexed keywords

3 METHYL 2 QUINOXALIN BENZENEVINYLKETO 1,4 DIOXIDE; ANTIINFECTIVE AGENT; BIOLOGICAL MARKER; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; QUINOCETONE; QUINOXALINE DERIVATIVE;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOACCUMULATION; CELL PROLIFERATION; CONTROLLED STUDY; DNA DAMAGE; HISTOPATHOLOGY; IMMUNOTOXICITY; LYMPHOCYTE FUNCTION; MALE; NATURAL KILLER CELL; NONHUMAN; ORGAN WEIGHT; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; SPLEEN; T LYMPHOCYTE; WEIGHT GAIN; ANIMAL; CELL CULTURE; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; IMMUNOLOGY; LIVER; METABOLISM; SPRAGUE DAWLEY RAT;

ANIMALS; CELLS, CULTURED; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, DRUG; LIVER; MALE; OXIDATIVE STRESS; QUINOXALINES; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; SPLEEN; T-LYMPHOCYTES;

EID: 84945464876     PISSN: 02732300     EISSN: 10960295     Source Type: Journal    
DOI: 10.1016/j.yrtph.2015.09.002     Document Type: Article

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