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Volumn 42, Issue 13, 2015, Pages 2029-2037

A pilot study imaging integrin αvβ3 with RGD PET/CT in suspected lung cancer patients

Author keywords

18F alfatide; Integrin v 3; Lung cancer; RGD PET

Indexed keywords

ARGININE GLYCINE ASPARTIC ACID ALFATIDE F 18; CONTRAST MEDIUM; TRACER; UNCLASSIFIED DRUG; VITRONECTIN RECEPTOR; 18F-ALF-NOTA-PRGD2; ALFATIDE II; COORDINATION COMPOUND; CYCLOPEPTIDE; RADIOPHARMACEUTICAL AGENT;

EID: 84945460342     PISSN: 16197070     EISSN: 16197089     Source Type: Journal    
DOI: 10.1007/s00259-015-3119-1     Document Type: Article
Times cited : (55)

References (34)
  • 1
    • 11844254414 scopus 로고    scopus 로고
    • Normalization of tumor vasculature: an emerging concept in antiangiogenic therapy
    • COI: 1:CAS:528:DC%2BD2MXnvFar, PID: 15637262
    • Jain RK. Normalization of tumor vasculature: an emerging concept in antiangiogenic therapy. Science. 2005;307:58–62.
    • (2005) Science , vol.307 , pp. 58-62
    • Jain, R.K.1
  • 2
    • 85013312416 scopus 로고
    • Tumor angiogenesis: therapeutic implications
    • COI: 1:STN:280:DyaE38%2FgvVCqsQ%3D%3D, PID: 4938153
    • Folkman J. Tumor angiogenesis: therapeutic implications. N Engl J Med. 1971;285:1182–6.
    • (1971) N Engl J Med , vol.285 , pp. 1182-1186
    • Folkman, J.1
  • 3
    • 80052607351 scopus 로고    scopus 로고
    • Efficacy of bevacizumab (Bev) plus chemotherapy (CT) compared to CT alone in previously untreated locally advanced or metastatic non-small cell lung cancer (NSCLC): systematic review and meta-analysis
    • PID: 21377753
    • Botrel TE, Clark O, Clark L, Paladini L, Faleiros E, Pegoretti B. Efficacy of bevacizumab (Bev) plus chemotherapy (CT) compared to CT alone in previously untreated locally advanced or metastatic non-small cell lung cancer (NSCLC): systematic review and meta-analysis. Lung Cancer. 2011;74:89–97.
    • (2011) Lung Cancer , vol.74 , pp. 89-97
    • Botrel, T.E.1    Clark, O.2    Clark, L.3    Paladini, L.4    Faleiros, E.5    Pegoretti, B.6
  • 4
    • 79959271064 scopus 로고    scopus 로고
    • Why integrin as a primary target for imaging and therapy
    • COI: 1:CAS:528:DC%2BC38Xislaltro%3D, PID: 21544229
    • Niu G, Chen X. Why integrin as a primary target for imaging and therapy. Theranostics. 2011;1:30–47.
    • (2011) Theranostics , vol.1 , pp. 30-47
    • Niu, G.1    Chen, X.2
  • 5
    • 72449156995 scopus 로고    scopus 로고
    • Radiolabeled cyclic RGD peptides as integrin alpha(v)beta(3)-targeted radiotracers: maximizing binding affinity via bivalency
    • COI: 1:CAS:528:DC%2BD1MXhtVKmurvJ, PID: 19719118
    • Liu S. Radiolabeled cyclic RGD peptides as integrin alpha(v)beta(3)-targeted radiotracers: maximizing binding affinity via bivalency. Bioconjug Chem. 2009;20:2199–213.
    • (2009) Bioconjug Chem , vol.20 , pp. 2199-2213
    • Liu, S.1
  • 6
    • 84868563717 scopus 로고    scopus 로고
    • RGD-based strategies to target alpha(v) beta(3) integrin in cancer therapy and diagnosis
    • COI: 1:CAS:528:DC%2BC38Xhtlaksr3O, PID: 22967287
    • Danhier F, Le BA, Preat V. RGD-based strategies to target alpha(v) beta(3) integrin in cancer therapy and diagnosis. Mol Pharm. 2012;9:2961–73.
    • (2012) Mol Pharm , vol.9 , pp. 2961-2973
    • Danhier, F.1    Le, B.A.2    Preat, V.3
  • 7
    • 80255141418 scopus 로고    scopus 로고
    • PET imaging of integrin alphaVbeta3 expression
    • COI: 1:CAS:528:DC%2BC38Xislaltrs%3D, PID: 21547152
    • Beer AJ, Kessler H, Wester HJ, Schwaiger M. PET imaging of integrin alphaVbeta3 expression. Theranostics. 2011;1:48–57.
    • (2011) Theranostics , vol.1 , pp. 48-57
    • Beer, A.J.1    Kessler, H.2    Wester, H.J.3    Schwaiger, M.4
  • 8
    • 79952784609 scopus 로고    scopus 로고
    • Monitoring tumor response to antiangiogenic sunitinib therapy with 18F-fluciclatide, an 18F-labeled alphaVbeta3-integrin and alphaV beta5-integrin imaging agent
    • COI: 1:CAS:528:DC%2BC3MXktVGnur8%3D, PID: 21321268
    • Battle MR, Goggi JL, Allen L, Barnett J, Morrison MS. Monitoring tumor response to antiangiogenic sunitinib therapy with 18F-fluciclatide, an 18F-labeled alphaVbeta3-integrin and alphaV beta5-integrin imaging agent. J Nucl Med. 2011;52:424–30.
    • (2011) J Nucl Med , vol.52 , pp. 424-430
    • Battle, M.R.1    Goggi, J.L.2    Allen, L.3    Barnett, J.4    Morrison, M.S.5
  • 9
    • 0023637601 scopus 로고
    • New perspectives in cell adhesion: RGD and integrins
    • COI: 1:CAS:528:DyaL1cXntVKkuw%3D%3D, PID: 2821619
    • Ruoslahti E, Pierschbacher MD. New perspectives in cell adhesion: RGD and integrins. Science. 1987;238:491–7.
    • (1987) Science , vol.238 , pp. 491-497
    • Ruoslahti, E.1    Pierschbacher, M.D.2
  • 10
    • 0032587186 scopus 로고    scopus 로고
    • Radiolabeled alpha(v)beta3 integrin antagonists: a new class of tracers for tumor targeting
    • COI: 1:CAS:528:DyaK1MXktVaqsLg%3D, PID: 10452325
    • Haubner R, Wester HJ, Reuning U, Senekowitsch-Schmidtke R, Diefenbach B, Kessler H, et al. Radiolabeled alpha(v)beta3 integrin antagonists: a new class of tracers for tumor targeting. J Nucl Med. 1999;40:1061–71.
    • (1999) J Nucl Med , vol.40 , pp. 1061-1071
    • Haubner, R.1    Wester, H.J.2    Reuning, U.3    Senekowitsch-Schmidtke, R.4    Diefenbach, B.5    Kessler, H.6
  • 11
    • 79952132377 scopus 로고    scopus 로고
    • PET imaging of alphavbeta3 expression in cancer patients
    • COI: 1:CAS:528:DC%2BC3MXhs12isb4%3D, PID: 21153382
    • Beer AJ, Schwaiger M. PET imaging of alphavbeta3 expression in cancer patients. Methods Mol Biol. 2011;680:183–200.
    • (2011) Methods Mol Biol , vol.680 , pp. 183-200
    • Beer, A.J.1    Schwaiger, M.2
  • 12
    • 12144287687 scopus 로고    scopus 로고
    • 18F-labeled RGD peptide: initial evaluation for imaging brain tumor angiogenesis
    • COI: 1:CAS:528:DC%2BD2cXhvVyht7g%3D, PID: 15013483
    • Chen X, Park R, Shahinian AH, Tohme M, Khankaldyyan V, Bozorgzadeh MH, et al. 18F-labeled RGD peptide: initial evaluation for imaging brain tumor angiogenesis. Nucl Med Biol. 2004;31:179–89.
    • (2004) Nucl Med Biol , vol.31 , pp. 179-189
    • Chen, X.1    Park, R.2    Shahinian, A.H.3    Tohme, M.4    Khankaldyyan, V.5    Bozorgzadeh, M.H.6
  • 13
    • 44149120982 scopus 로고    scopus 로고
    • Preparation of a promising angiogenesis PET imaging agent: 68Ga-labeled c(RGDyK)-isothiocyanatobenzyl-1,4,7-triazacyclononane-1,4,7-triacetic acid and feasibility studies in mice
    • COI: 1:CAS:528:DC%2BD1cXmvVSju7k%3D, PID: 18413379
    • Jeong JM, Hong MK, Chang YS, Lee YS, Kim YJ, Cheon GJ, et al. Preparation of a promising angiogenesis PET imaging agent: 68Ga-labeled c(RGDyK)-isothiocyanatobenzyl-1,4,7-triazacyclononane-1,4,7-triacetic acid and feasibility studies in mice. J Nucl Med. 2008;49:830–6.
    • (2008) J Nucl Med , vol.49 , pp. 830-836
    • Jeong, J.M.1    Hong, M.K.2    Chang, Y.S.3    Lee, Y.S.4    Kim, Y.J.5    Cheon, G.J.6
  • 14
    • 43749105336 scopus 로고    scopus 로고
    • (68)Ga-labeled multimeric RGD peptides for microPET imaging of integrin alpha(v)beta (3) expression
    • COI: 1:CAS:528:DC%2BD1cXlvVClt70%3D, PID: 18204838
    • Li ZB, Chen K, Chen X. (68)Ga-labeled multimeric RGD peptides for microPET imaging of integrin alpha(v)beta (3) expression. Eur J Nucl Med Mol Imaging. 2008;35:1100–8.
    • (2008) Eur J Nucl Med Mol Imaging , vol.35 , pp. 1100-1108
    • Li, Z.B.1    Chen, K.2    Chen, X.3
  • 15
    • 4544387211 scopus 로고    scopus 로고
    • MicroPET imaging of breast cancer alphav-integrin expression with 64Cu-labeled dimeric RGD peptides
    • PID: 15380745
    • Chen X, Liu S, Hou Y, Tohme M, Park R, Bading JR, et al. MicroPET imaging of breast cancer alphav-integrin expression with 64Cu-labeled dimeric RGD peptides. Mol Imaging Biol. 2004;6:350–9.
    • (2004) Mol Imaging Biol , vol.6 , pp. 350-359
    • Chen, X.1    Liu, S.2    Hou, Y.3    Tohme, M.4    Park, R.5    Bading, J.R.6
  • 16
    • 84872155536 scopus 로고    scopus 로고
    • New methods for labeling RGD peptides with bromine-76
    • COI: 1:CAS:528:DC%2BC38XislaltLg%3D, PID: 21938262
    • Lang L, Li W, Jia HM, Fang DC, Zhang S, Sun X, et al. New methods for labeling RGD peptides with bromine-76. Theranostics. 2011;1:341–53.
    • (2011) Theranostics , vol.1 , pp. 341-353
    • Lang, L.1    Li, W.2    Jia, H.M.3    Fang, D.C.4    Zhang, S.5    Sun, X.6
  • 17
    • 84855651759 scopus 로고    scopus 로고
    • MicroPET imaging of integrin alphavbeta3 expressing tumors using 89Zr-RGD peptides
    • PID: 21161690
    • Jacobson O, Zhu L, Niu G, Weiss ID, Szajek LP, Ma Y, et al. MicroPET imaging of integrin alphavbeta3 expressing tumors using 89Zr-RGD peptides. Mol Imaging Biol. 2011;13:1224–33.
    • (2011) Mol Imaging Biol , vol.13 , pp. 1224-1233
    • Jacobson, O.1    Zhu, L.2    Niu, G.3    Weiss, I.D.4    Szajek, L.P.5    Ma, Y.6
  • 18
    • 18244376347 scopus 로고    scopus 로고
    • Noninvasive visualization of the activated alphavbeta3 integrin in cancer patients by positron emission tomography and [18F]Galacto-RGD
    • PID: 15783258
    • Haubner R, Weber WA, Beer AJ, Vabuliene E, Reim D, Sarbia M, et al. Noninvasive visualization of the activated alphavbeta3 integrin in cancer patients by positron emission tomography and [18F]Galacto-RGD. PLoS Med. 2005;2:e70.
    • (2005) PLoS Med , vol.2 , pp. e70
    • Haubner, R.1    Weber, W.A.2    Beer, A.J.3    Vabuliene, E.4    Reim, D.5    Sarbia, M.6
  • 19
    • 0035266374 scopus 로고    scopus 로고
    • Noninvasive imaging of alpha(v)beta3 integrin expression using 18F-labeled RGD-containing glycopeptide and positron emission tomography
    • COI: 1:CAS:528:DC%2BD3MXit1Ohtbk%3D, PID: 11280722
    • Haubner R, Wester HJ, Weber WA, Mang C, Ziegler SI, Goodman SL, et al. Noninvasive imaging of alpha(v)beta3 integrin expression using 18F-labeled RGD-containing glycopeptide and positron emission tomography. Cancer Res. 2001;61:1781–5.
    • (2001) Cancer Res , vol.61 , pp. 1781-1785
    • Haubner, R.1    Wester, H.J.2    Weber, W.A.3    Mang, C.4    Ziegler, S.I.5    Goodman, S.L.6
  • 20
    • 25444503494 scopus 로고    scopus 로고
    • Biodistribution and pharmacokinetics of the alphavbeta3-selective tracer 18F-galacto-RGD in cancer patients
    • COI: 1:CAS:528:DC%2BD28XitVGlsb8%3D, PID: 16085591
    • Beer AJ, Haubner R, Goebel M, Luderschmidt S, Spilker ME, Wester HJ, et al. Biodistribution and pharmacokinetics of the alphavbeta3-selective tracer 18F-galacto-RGD in cancer patients. J Nucl Med. 2005;46:1333–41.
    • (2005) J Nucl Med , vol.46 , pp. 1333-1341
    • Beer, A.J.1    Haubner, R.2    Goebel, M.3    Luderschmidt, S.4    Spilker, M.E.5    Wester, H.J.6
  • 21
    • 33746032220 scopus 로고    scopus 로고
    • Positron emission tomography using [18F]Galacto-RGD identifies the level of integrin alpha(v)beta3 expression in man
    • COI: 1:CAS:528:DC%2BD28XmsValtLk%3D, PID: 16818691
    • Beer AJ, Haubner R, Sarbia M, Goebel M, Luderschmidt S, Grosu AL, et al. Positron emission tomography using [18F]Galacto-RGD identifies the level of integrin alpha(v)beta3 expression in man. Clin Cancer Res. 2006;12:3942–9.
    • (2006) Clin Cancer Res , vol.12 , pp. 3942-3949
    • Beer, A.J.1    Haubner, R.2    Sarbia, M.3    Goebel, M.4    Luderschmidt, S.5    Grosu, A.L.6
  • 22
    • 53749107069 scopus 로고    scopus 로고
    • The biodistribution and radiation dosimetry of the Arg-Gly-Asp peptide 18F-AH111585 in healthy volunteers
    • PID: 18794263
    • McParland BJ, Miller MP, Spinks TJ, Kenny LM, Osman S, Khela MK, et al. The biodistribution and radiation dosimetry of the Arg-Gly-Asp peptide 18F-AH111585 in healthy volunteers. J Nucl Med. 2008;49:1664–7.
    • (2008) J Nucl Med , vol.49 , pp. 1664-1667
    • McParland, B.J.1    Miller, M.P.2    Spinks, T.J.3    Kenny, L.M.4    Osman, S.5    Khela, M.K.6
  • 23
    • 44849137859 scopus 로고    scopus 로고
    • Phase I trial of the positron-emitting Arg-Gly-Asp (RGD) peptide radioligand 18F-AH111585 in breast cancer patients
    • PID: 18483090
    • Kenny LM, Coombes RC, Oulie I, Contractor KB, Miller M, Spinks TJ, et al. Phase I trial of the positron-emitting Arg-Gly-Asp (RGD) peptide radioligand 18F-AH111585 in breast cancer patients. J Nucl Med. 2008;49:879–86.
    • (2008) J Nucl Med , vol.49 , pp. 879-886
    • Kenny, L.M.1    Coombes, R.C.2    Oulie, I.3    Contractor, K.B.4    Miller, M.5    Spinks, T.J.6
  • 24
    • 84860703203 scopus 로고    scopus 로고
    • Biodistribution and radiation dosimetry of the integrin marker 18F-RGD-K5 determined from whole-body PET/CT in monkeys and humans
    • PID: 22499613
    • Doss M, Kolb HC, Zhang JJ, Belanger MJ, Stubbs JB, Stabin MG, et al. Biodistribution and radiation dosimetry of the integrin marker 18F-RGD-K5 determined from whole-body PET/CT in monkeys and humans. J Nucl Med. 2012;53:787–95.
    • (2012) J Nucl Med , vol.53 , pp. 787-795
    • Doss, M.1    Kolb, H.C.2    Zhang, J.J.3    Belanger, M.J.4    Stubbs, J.B.5    Stabin, M.G.6
  • 25
    • 79959567221 scopus 로고    scopus 로고
    • Pilot pharmacokinetic and dosimetric studies of (18)F-FPPRGD2: a PET radiopharmaceutical agent for imaging alpha(v)beta(3) integrin levels
    • PID: 21502381
    • Mittra ES, Goris ML, Iagaru AH, Kardan A, Burton L, Berganos R, et al. Pilot pharmacokinetic and dosimetric studies of (18)F-FPPRGD2: a PET radiopharmaceutical agent for imaging alpha(v)beta(3) integrin levels. Radiology. 2011;260:182–91.
    • (2011) Radiology , vol.260 , pp. 182-191
    • Mittra, E.S.1    Goris, M.L.2    Iagaru, A.H.3    Kardan, A.4    Burton, L.5    Berganos, R.6
  • 26
    • 38949212117 scopus 로고    scopus 로고
    • Patterns of alphavbeta3 expression in primary and metastatic human breast cancer as shown by 18F-Galacto-RGD PET
    • PID: 18199623
    • Beer AJ, Niemeyer M, Carlsen J, Sarbia M, Nahrig J, Watzlowik P, et al. Patterns of alphavbeta3 expression in primary and metastatic human breast cancer as shown by 18F-Galacto-RGD PET. J Nucl Med. 2008;49:255–9.
    • (2008) J Nucl Med , vol.49 , pp. 255-259
    • Beer, A.J.1    Niemeyer, M.2    Carlsen, J.3    Sarbia, M.4    Nahrig, J.5    Watzlowik, P.6
  • 27
    • 72449174017 scopus 로고    scopus 로고
    • Imaging of integrin alpha(v)beta(3) expression in patients with malignant glioma by [18F] Galacto-RGD positron emission tomography
    • PID: 19401596
    • Schnell O, Krebs B, Carlsen J, Miederer I, Goetz C, Goldbrunner RH, et al. Imaging of integrin alpha(v)beta(3) expression in patients with malignant glioma by [18F] Galacto-RGD positron emission tomography. Neuro Oncol. 2009;11:861–70.
    • (2009) Neuro Oncol , vol.11 , pp. 861-870
    • Schnell, O.1    Krebs, B.2    Carlsen, J.3    Miederer, I.4    Goetz, C.5    Goldbrunner, R.H.6
  • 28
    • 36749053493 scopus 로고    scopus 로고
    • [18F]galacto-RGD positron emission tomography for imaging of alphavbeta3 expression on the neovasculature in patients with squamous cell carcinoma of the head and neck
    • COI: 1:CAS:528:DC%2BD2sXhtlSmu7nO, PID: 18006761
    • Beer AJ, Grosu AL, Carlsen J, Kolk A, Sarbia M, Stangier I, et al. [18F]galacto-RGD positron emission tomography for imaging of alphavbeta3 expression on the neovasculature in patients with squamous cell carcinoma of the head and neck. Clin Cancer Res. 2007;13:6610–6.
    • (2007) Clin Cancer Res , vol.13 , pp. 6610-6616
    • Beer, A.J.1    Grosu, A.L.2    Carlsen, J.3    Kolk, A.4    Sarbia, M.5    Stangier, I.6
  • 30
    • 84555177937 scopus 로고    scopus 로고
    • Comparison study of [18F]FAl-NOTA-PRGD2, [18F]FPPRGD2, and [68Ga]Ga-NOTA-PRGD2 for PET imaging of U87MG tumors in mice
    • COI: 1:CAS:528:DC%2BC3MXhtlKjs77J, PID: 22026940
    • Lang L, Li W, Guo N, Ma Y, Zhu L, Kiesewetter DO, et al. Comparison study of [18F]FAl-NOTA-PRGD2, [18F]FPPRGD2, and [68Ga]Ga-NOTA-PRGD2 for PET imaging of U87MG tumors in mice. Bioconjug Chem. 2011;22:2415–22.
    • (2011) Bioconjug Chem , vol.22 , pp. 2415-2422
    • Lang, L.1    Li, W.2    Guo, N.3    Ma, Y.4    Zhu, L.5    Kiesewetter, D.O.6
  • 31
    • 84877116526 scopus 로고    scopus 로고
    • First experience of 18F-alfatide in lung cancer patients using a new lyophilized kit for rapid radiofluorination
    • COI: 1:CAS:528:DC%2BC3sXosFCns7g%3D, PID: 23554506
    • Wan W, Guo N, Pan D, Yu C, Weng Y, Luo S, et al. First experience of 18F-alfatide in lung cancer patients using a new lyophilized kit for rapid radiofluorination. J Nucl Med. 2013;54:691–8.
    • (2013) J Nucl Med , vol.54 , pp. 691-698
    • Wan, W.1    Guo, N.2    Pan, D.3    Yu, C.4    Weng, Y.5    Luo, S.6
  • 32
    • 23844497055 scopus 로고    scopus 로고
    • Non-small cell lung cancer: prospective comparison of integrated FDG PET/CT and CT alone for preoperative staging
    • PID: 16014441
    • Shim SS, Lee KS, Kim BT, Chung MJ, Lee EJ, Han J, et al. Non-small cell lung cancer: prospective comparison of integrated FDG PET/CT and CT alone for preoperative staging. Radiology. 2005;236:1011–9.
    • (2005) Radiology , vol.236 , pp. 1011-1019
    • Shim, S.S.1    Lee, K.S.2    Kim, B.T.3    Chung, M.J.4    Lee, E.J.5    Han, J.6
  • 33
    • 45649084478 scopus 로고    scopus 로고
    • Value of PET/CT versus enhanced CT for locoregional lymph nodes in non-small cell lung cancer
    • PID: 18177978
    • Yang W, Fu Z, Yu J, Yuan S, Zhang B, Li D, et al. Value of PET/CT versus enhanced CT for locoregional lymph nodes in non-small cell lung cancer. Lung Cancer. 2008;61:35–43.
    • (2008) Lung Cancer , vol.61 , pp. 35-43
    • Yang, W.1    Fu, Z.2    Yu, J.3    Yuan, S.4    Zhang, B.5    Li, D.6
  • 34
    • 33749055116 scopus 로고    scopus 로고
    • Additional value of PET/CT over PET in assessment of locoregional lymph nodes in thoracic esophageal squamous cell cancer
    • PID: 16883002
    • Yuan S, Yu Y, Chao KS, Fu Z, Yin Y, Liu T, et al. Additional value of PET/CT over PET in assessment of locoregional lymph nodes in thoracic esophageal squamous cell cancer. J Nucl Med. 2006;47:1255–9.
    • (2006) J Nucl Med , vol.47 , pp. 1255-1259
    • Yuan, S.1    Yu, Y.2    Chao, K.S.3    Fu, Z.4    Yin, Y.5    Liu, T.6


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