메뉴 건너뛰기




Volumn 260, Issue 1, 2011, Pages 182-191

Pilot pharmacokinetic and dosimetric studies of18F-FPPRGD2: A PET radiopharmaceutical agent for imaging αvβ3 integrin levels

Author keywords

[No Author keywords available]

Indexed keywords

2 FLUOROPROPIONYL PEGYLATED ARGINYLGLYCYLASPARTIC ACID F 18; RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG; VITRONECTIN RECEPTOR;

EID: 79959567221     PISSN: 00338419     EISSN: 15271315     Source Type: Journal    
DOI: 10.1148/radiol.11101139     Document Type: Article
Times cited : (130)

References (38)
  • 1
    • 0030636257 scopus 로고    scopus 로고
    • Angiogenesis and angiogenesis inhibition: An overview
    • Folkman J. Angiogenesis and angiogenesis inhibition: an overview. EXS 1997;79:1-8.
    • (1997) EXS , vol.79 , pp. 1-8
    • Folkman, J.1
  • 2
    • 0036984640 scopus 로고    scopus 로고
    • Role of angiogenesis in tumor growth and metastasis
    • Folkman J. Role of angiogenesis in tumor growth and metastasis. Semin Oncol 2002;29(6 Suppl 16):15-18.
    • (2002) Semin Oncol , vol.29 , Issue.6 SUPPL. 16 , pp. 15-18
    • Folkman, J.1
  • 3
    • 2642571660 scopus 로고    scopus 로고
    • Vascular-targeting therapies for treatment of malignant disease
    • DOI 10.1002/cncr.20299
    • Siemann DW, Chaplin DJ, Horsman MR. Vascular-targeting therapies for treatment of malignant disease. Cancer 2004;100(12):2491-2499. (Pubitemid 38715753)
    • (2004) Cancer , vol.100 , Issue.12 , pp. 2491-2499
    • Siemann, D.W.1    Chaplin, D.J.2    Horsman, M.R.3
  • 4
    • 0037242284 scopus 로고    scopus 로고
    • Reduction of vascular and permeable regions in solid tumors detected by macromolecular contrast magnetic resonance imaging after treatment with antiangiogenic agent TNP-470
    • Bhujwalla ZM, Artemov D, Natarajan K, Solaiyappan M, Kollars P, Kristjansen PE. Reduction of vascular and permeable regions in solid tumors detected by macromolecular contrast magnetic resonance imaging after treatment with antiangiogenic agent TNP-470. Clin Cancer Res 2003;9(1):355-362. (Pubitemid 36109752)
    • (2003) Clinical Cancer Research , vol.9 , Issue.1 I , pp. 355-362
    • Bhujwalla, Z.M.1    Artemov, D.2    Natarajan, K.3    Solaiyappan, M.4    Kollars, P.5    Kristjansen, P.E.G.6
  • 5
    • 0033943076 scopus 로고    scopus 로고
    • Role of alpha v integrins during angiogenesis
    • Eliceiri BP, Cheresh DA. Role of alpha v integrins during angiogenesis. Cancer J 2000;6(Suppl 3):S245-S249.
    • (2000) Cancer J , vol.6 , Issue.SUPPL. 3
    • Eliceiri, B.P.1    Cheresh, D.A.2
  • 7
    • 0036904072 scopus 로고    scopus 로고
    • v integrin antagonists as novel anticancer agents: An update
    • DOI 10.1517/13543784.11.12.1765
    • Kerr JS, Slee AM, Mousa SA. The alpha v integrin antagonists as novel anticancer agents: an update. Expert Opin Investig Drugs 2002;11(12):1765-1774. (Pubitemid 35476838)
    • (2002) Expert Opinion on Investigational Drugs , vol.11 , Issue.12 , pp. 1765-1774
    • Kerr, J.S.1    Slee, A.M.2    Mousa, S.A.3
  • 8
    • 2342439574 scopus 로고    scopus 로고
    • Radiolabeled tracers for imaging of tumor angiogenesis and evaluation of anti-angiogenic therapies
    • DOI 10.2174/1381612043384745
    • Haubner R, Wester HJ. Radiolabeled tracers for imaging of tumor angiogenesis and evaluation of anti-angiogenic therapies. Curr Pharm Des 2004;10(13):1439-1455. (Pubitemid 38559759)
    • (2004) Current Pharmaceutical Design , vol.10 , Issue.13 , pp. 1439-1455
    • Haubner, R.1    Wester, H.-J.2
  • 9
    • 53749084254 scopus 로고    scopus 로고
    • Targeted microbubbles for imaging tumor angiogenesis: Assessment of whole-body biodistribution with dynamic micro-PET in mice
    • Willmann JK, Cheng Z, Davis C, et al. Targeted microbubbles for imaging tumor angiogenesis: assessment of whole-body biodistribution with dynamic micro-PET in mice. Radiology 2008;249(1):212-219.
    • (2008) Radiology , vol.249 , Issue.1 , pp. 212-219
    • Willmann, J.K.1    Cheng, Z.2    Davis, C.3
  • 10
    • 77950344627 scopus 로고    scopus 로고
    • Targeted contrast-enhanced ultrasound imaging of tumor angiogenesis with contrast microbubbles conjugated to integrin-binding knottin peptides
    • Willmann JK, Kimura RH, Deshpande N, Lutz AM, Cochran JR, Gambhir SS. Targeted contrast-enhanced ultrasound imaging of tumor angiogenesis with contrast microbubbles conjugated to integrin-binding knottin peptides. J Nucl Med 2010;51(3):433-440.
    • (2010) J Nucl Med , vol.51 , Issue.3 , pp. 433-440
    • Willmann, J.K.1    Kimura, R.H.2    Deshpande, N.3    Lutz, A.M.4    Cochran, J.R.5    Gambhir, S.S.6
  • 11
    • 51549083693 scopus 로고    scopus 로고
    • Dual-targeted contrast agent for US assessment of tumor angiogenesis in vivo
    • Willmann JK, Lutz AM, Paulmurugan R, et al. Dual-targeted contrast agent for US assessment of tumor angiogenesis in vivo. Radiology 2008;248(3):936-944.
    • (2008) Radiology , vol.248 , Issue.3 , pp. 936-944
    • Willmann, J.K.1    Lutz, A.M.2    Paulmurugan, R.3
  • 12
    • 39549106031 scopus 로고    scopus 로고
    • US imaging of tumor angiogenesis with microbubbles targeted to vascular endothelial growth factor receptor type 2 in mice
    • Willmann JK, Paulmurugan R, Chen K, et al. US imaging of tumor angiogenesis with microbubbles targeted to vascular endothelial growth factor receptor type 2 in mice. Radiology 2008;246(2):508-518.
    • (2008) Radiology , vol.246 , Issue.2 , pp. 508-518
    • Willmann, J.K.1    Paulmurugan, R.2    Chen, K.3
  • 14
    • 7444235966 scopus 로고    scopus 로고
    • In vivo near-infrared fluorescence imaging of integrin alphavbeta3 in brain tumor xenografts
    • Chen X, Conti PS, Moats RA. In vivo near-infrared fluorescence imaging of integrin alphavbeta3 in brain tumor xenografts. Cancer Res 2004;64(21):8009- 8014.
    • (2004) Cancer Res , vol.64 , Issue.21 , pp. 8009-8014
    • Chen, X.1    Conti, P.S.2    Moats, R.A.3
  • 16
    • 0036717382 scopus 로고    scopus 로고
    • Molecular imaging of cancer with positron emission tomography
    • DOI 10.1038/nrc882
    • Gambhir SS. Molecular imaging of cancer with positron emission tomography. Nat Rev Cancer 2002;2(9):683-693. (Pubitemid 37328919)
    • (2002) Nature Reviews Cancer , vol.2 , Issue.9 , pp. 683-693
    • Gambhir, S.S.1
  • 17
    • 0842263586 scopus 로고    scopus 로고
    • [18F]Galacto-RGD: Synthesis, radiolabeling, metabolic stability, and radiation dose estimates
    • Haubner R, Kuhnast B, Mang C, et al. [18F]Galacto-RGD: synthesis, radiolabeling, metabolic stability, and radiation dose estimates. Bioconjug Chem 2004;15(1):61-69.
    • (2004) Bioconjug Chem , vol.15 , Issue.1 , pp. 61-69
    • Haubner, R.1    Kuhnast, B.2    Mang, C.3
  • 18
    • 0035266374 scopus 로고    scopus 로고
    • Noninvasive imaging of alpha(v)beta3 integrin expression using 18F-labeled RGD-containing glycopeptide and positron emission tomography
    • Haubner R, Wester HJ, Weber WA, et al. Noninvasive imaging of alpha(v)beta3 integrin expression using 18F-labeled RGD-containing glycopeptide and positron emission tomography. Cancer Res 2001;61(5):1781-1785.
    • (2001) Cancer Res , vol.61 , Issue.5 , pp. 1781-1785
    • Haubner, R.1    Wester, H.J.2    Weber, W.A.3
  • 19
    • 18244376347 scopus 로고    scopus 로고
    • Noninvasive visualization of the activated alphavbeta3 integrin in cancer patients by positron emission tomography and [18F] Galacto-RGD
    • Haubner R, Weber WA, Beer AJ, et al. Noninvasive visualization of the activated alphavbeta3 integrin in cancer patients by positron emission tomography and [18F] Galacto-RGD. PLoS Med 2005;2(3):e70.
    • (2005) PLoS Med , vol.2 , Issue.3
    • Haubner, R.1    Weber, W.A.2    Beer, A.J.3
  • 22
    • 0347517810 scopus 로고    scopus 로고
    • Novel targeting strategy based on multimeric ligands for drug delivery and molecular imaging: Homooligomers of alpha-MSH
    • DOI 10.1016/j.bmcl.2003.09.079
    • Vagner J, Handl HL, Gillies RJ, Hruby VJ. Novel targeting strategy based on multimeric ligands for drug delivery and molecular imaging: homooligomers of alpha-MSH. Bioorg Med Chem Lett 2004;14(1):211-215. (Pubitemid 38010222)
    • (2004) Bioorganic and Medicinal Chemistry Letters , vol.14 , Issue.1 , pp. 211-215
    • Vagner, J.1    Handl, H.L.2    Gillies, R.J.3    Hruby, V.J.4
  • 23
    • 0032076568 scopus 로고    scopus 로고
    • A trivalent system from vancomycin. D-ala-D-Ala with higher affinity than avidin. biotin
    • Rao J, Lahiri J, Isaacs L, Weis RM, Whitesides GM. A trivalent system from vancomycin. D-ala-D-Ala with higher affinity than avidin. biotin. Science 1998;280(5364):708-711.
    • (1998) Science , vol.280 , Issue.5364 , pp. 708-711
    • Rao, J.1    Lahiri, J.2    Isaacs, L.3    Weis, R.M.4    Whitesides, G.M.5
  • 24
    • 43749105336 scopus 로고    scopus 로고
    • (68)Ga-labeled multi-meric RGD peptides for microPET imaging of integrin alpha(v)beta (3) expression
    • Li ZB, Chen K, Chen X. (68)Ga-labeled multi-meric RGD peptides for microPET imaging of integrin alpha(v)beta (3) expression. Eur J Nucl Med Mol Imaging 2008;35(6):1100-1108.
    • (2008) Eur J Nucl Med Mol Imaging , vol.35 , Issue.6 , pp. 1100-1108
    • Li, Z.B.1    Chen, K.2    Chen, X.3
  • 25
    • 36849012163 scopus 로고    scopus 로고
    • Click chemistry for (18)F-labeling of RGD peptides and microPET imaging of tumor integrin alphavbeta3 expression
    • Li ZB, Wu Z, Chen K, Chin FT, Chen X. Click chemistry for (18)F-labeling of RGD peptides and microPET imaging of tumor integrin alphavbeta3 expression. Bioconjug Chem 2007;18(6):1987-1994.
    • (2007) Bioconjug Chem , vol.18 , Issue.6 , pp. 1987-1994
    • Li, Z.B.1    Wu, Z.2    Chen, K.3    Chin, F.T.4    Chen, X.5
  • 27
    • 34447336118 scopus 로고    scopus 로고
    • (64)Cu-labeled tetrameric and octameric RGD peptides for small-animal PET of tumor alpha(v)beta(3) integrin expression
    • Li ZB, Cai W, Cao Q, et al. (64)Cu-labeled tetrameric and octameric RGD peptides for small-animal PET of tumor alpha(v)beta(3) integrin expression. J Nucl Med 2007;48(7):1162-1171.
    • (2007) J Nucl Med , vol.48 , Issue.7 , pp. 1162-1171
    • Li, Z.B.1    Cai, W.2    Cao, Q.3
  • 29
    • 77956264376 scopus 로고    scopus 로고
    • 18F-labeled galacto and PEGylated RGD dimers for PET imaging of a v b 3 integrin expression
    • Liu S, Liu Z, Chen K, et al. 18F-labeled galacto and PEGylated RGD dimers for PET imaging of a v b 3 integrin expression. Mol Imaging Biol 2010;12(5):530-538.
    • (2010) Mol Imaging Biol , vol.12 , Issue.5 , pp. 530-538
    • Liu, S.1    Liu, Z.2    Chen, K.3
  • 30
    • 79959554639 scopus 로고    scopus 로고
    • Initial experience with clinical-grade [18F]FPP(RGD)2: An automated multi-step radiosynthesis for clinical PET studies
    • in press
    • Chin FT, Shen B, Liu S, et al. Initial experience with clinical-grade [18F]FPP(RGD)2: an automated multi-step radiosynthesis for clinical PET studies. J Nucl Med(in press ).
    • J Nucl Med
    • Chin, F.T.1    Shen, B.2    Liu, S.3
  • 31
    • 84861481740 scopus 로고    scopus 로고
    • 2: An automated multi-step radiosynthesis for clinical PET studies
    • in press
    • 2: an automated multi-step radiosynthesis for clinical PET studies. Mol Imaging Biol (in press).
    • Mol Imaging Biol
    • Chin, F.T.1    Shen, B.2    Liu, S.3
  • 32
    • 23044470017 scopus 로고    scopus 로고
    • OLINDA/EXM: The second-generation personal computer software for internal dose assessment in nuclear medicine
    • Stabin MG, Sparks RB, Crowe E. OLINDA/ EXM: the second-generation personal computer software for internal dose assessment in nuclear medicine. J Nucl Med 2005;46(6):1023-1027. (Pubitemid 43733519)
    • (2005) Journal of Nuclear Medicine , vol.46 , Issue.6 , pp. 1023-1027
    • Stabin, M.G.1    Sparks, R.B.2    Crowe, E.3
  • 33
    • 58149130161 scopus 로고    scopus 로고
    • Radiation protection in medicine. ICRP publication 105
    • International Commission on Radiological Protection
    • International Commission on Radiological Protection. Radiation protection in medicine. ICRP publication 105. Ann ICRP 2007;37(6):1-63.
    • (2007) Ann ICRP , vol.37 , Issue.6 , pp. 1-63
  • 34
    • 40949104442 scopus 로고    scopus 로고
    • The 2007 recommendations of the International Commission on Radiological Protection
    • International Commission on Radiological Protection ICRP publication 103
    • International Commission on Radiological Protection. The 2007 recommendations of the International Commission on Radiological Protection. ICRP publication 103. Ann ICRP 2007;37(2-4):1-332.
    • (2007) Ann ICRP , vol.37 , Issue.2-4 , pp. 1-332
  • 35
    • 52549109852 scopus 로고    scopus 로고
    • Imaging of integrin alphavbeta3 expression
    • Beer AJ, Schwaiger M. Imaging of integrin alphavbeta3 expression. Cancer Metastasis Rev 2008;27(4):631-644.
    • (2008) Cancer Metastasis Rev , vol.27 , Issue.4 , pp. 631-644
    • Beer, A.J.1    Schwaiger, M.2
  • 36
    • 77953343406 scopus 로고    scopus 로고
    • Radiation exposure of patients and personnel from a PET/CT procedure with 18F-FDG
    • Leide-Svegborn S. Radiation exposure of patients and personnel from a PET/CT procedure with 18F-FDG. Radiat Prot Dosimetry 2010;139(1-3):208-213.
    • (2010) Radiat Prot Dosimetry , vol.139 , Issue.1-3 , pp. 208-213
    • Leide-Svegborn, S.1
  • 37
    • 53749107069 scopus 로고    scopus 로고
    • The biodistribution and radiation dosimetry of the Arg-Gly-Asp peptide 18F-AH111585 in healthy volunteers
    • McParland BJ, Miller MP, Spinks TJ, et al. The biodistribution and radiation dosimetry of the Arg-Gly-Asp peptide 18F-AH111585 in healthy volunteers. J Nucl Med 2008;49(10):1664-1667.
    • (2008) J Nucl Med , vol.49 , Issue.10 , pp. 1664-1667
    • McParland, B.J.1    Miller, M.P.2    Spinks, T.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.