Genomic resolution of an aggressive, widespread, diverse and expanding meningococcal serogroup B, C and W lineage

Journal of Infection

Volumn 71, Issue 5, 2015, Pages 544-552

  Lucidarme, Jay ^a   Hill, Dorothea M C ^b   Bratcher, Holly B ^b   Gray, Steve J ^a   du Plessis, Mignon ^c   Tsang, Raymond S W ^d   Vazquez, Julio A ^e   Taha, Muhamed Kheir ^f   Ceyhan, Mehmet ^g   Efron, Adriana M ^h   Gorla, Maria C ⁱ   Findlow, Jamie ^a   Jolley, Keith A ^b   Maiden, Martin C J ^b   Borrow, Ray ^a  

^a MANCHESTER ROYAL INFIRMARY   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c NATIONAL INSTITUTE FOR COMMUNICABLE DISEASES   (South Africa)

^d PUBLIC HEALTH AGENCY OF CANADA   (Canada)

^e INSTITUTO DE SALUD CARLOS III   (Spain)

^f INSTITUT PASTEUR   (France)

^g HACETTEPE UNIVERSITY   (Turkey)

^h INSTITUTO NACIONAL DE ENFERMEDADES INFECCIOSAS   (Argentina)

ⁱ INSTITUTO ADOLFO LUTZ   (Brazil)

Author keywords

Genome; Meningococcal; Serogroup C; Serogroup W; ST 11 clonal complex

Indexed keywords

ARTICLE; BACTERIAL GENE; BACTERIAL GENOME; BACTERIAL STRAIN; BACTERIUM ISOLATE; COMPARATIVE STUDY; CONTROLLED STUDY; DNA POLYMORPHISM; FRANCE; FUMC GENE; GENE CLUSTER; GENE SEQUENCE; GENETIC VARIABILITY; GENOMIC RESOLUTION; GEOGRAPHICAL VARIATION (SPECIES); MEN WHO HAVE SEX WITH MEN; MOLECULAR CLONING; MOLECULAR GENETICS; NEISSERIA MENINGITIDIS; NEISSERIA MENINGITIDIS SOUTH AMERICAN UK SEROGROUP W; NONHUMAN; PHYLOGENETIC TREE; POPULATION STRUCTURE; SPECIES DISTRIBUTION; UNITED KINGDOM; CLASSIFICATION; ENDEMIC DISEASE; EPIDEMIC; GENETICS; HUMAN; ISOLATION AND PURIFICATION; MALE; MALE HOMOSEXUALITY; MENINGOCOCCAL INFECTIONS; MICROBIOLOGY; MULTILOCUS SEQUENCE TYPING; NORTH AMERICA; PHYLOGENY; SEROTYPE; SEROTYPING; SOUTH AFRICA; SOUTH AMERICA;

DISEASE OUTBREAKS; ENDEMIC DISEASES; FRANCE; HOMOSEXUALITY, MALE; HUMANS; MALE; MENINGOCOCCAL INFECTIONS; MULTILOCUS SEQUENCE TYPING; NEISSERIA MENINGITIDIS; NEISSERIA MENINGITIDIS, SEROGROUP B; NEISSERIA MENINGITIDIS, SEROGROUP C; NORTH AMERICA; PHYLOGENY; SEROGROUP; SEROTYPING; SOUTH AFRICA; SOUTH AMERICA; UNITED KINGDOM;

EID: 84945458670     PISSN: 01634453     EISSN: 15322742     Source Type: Journal    
DOI: 10.1016/j.jinf.2015.07.007     Document Type: Article

References (30)

1. Halperin S.A., Bettinger J.A., Greenwood B., Harrison L.H., Jelfs J., Ladhani S.N., et al. The changing and dynamic epidemiology of meningococcal disease. Vaccine 2012, 30(Suppl. 2):B26-B36.
2. Cohn A.C., Harrison L.H. Meningococcal vaccines: current issues and future strategies. Drugs 2013, 73(11):1147-1155.
3. Jolley K.A., Brehony C., Maiden M.C. Molecular typing of meningococci: recommendations for target choice and nomenclature. FEMS Microbiol Rev 2007, 31(1):89-96.
4. Trotter C.L., Fox A.J., Ramsay M.E., Sadler F., Gray S.J., Mallard R., et al. Fatal outcome from meningococcal disease-an association with meningococcal phenotype but not with reduced susceptibility to benzylpenicillin. J Med Microbiol 2002, 51(10):855-860.
5. Brundage J.F., Zollinger W.D. Evolution of meningococcal disease epidemiology in the US army. Evolution of meningococcal disease 1987, CRC Press, Boca Raton. N.A. Vedros (Ed.).
6. Borrow R., Abad R., Trotter C., van der Klis F.R., Vazquez J.A. Effectiveness of meningococcal serogroup C vaccine programmes. Vaccine 2013, 31(41):4477-4486.
7. Mayer L.W., Reeves M.W., Al-Hamdan N., Sacchi C.T., Taha M.K., Ajello G.W., et al. Outbreak of W135 meningococcal disease in 2000: not emergence of a new W135 strain but clonal expansion within the electophoretic type-37 complex. J Infect Dis 2002, 185(11):1596-1605.
8. Njanpop-Lafourcade B.M., Parent du Chatelet I., Sanou O., Alonso J.M., Taha M.K. The establishment of Neisseria meningitidis serogroup W135 of the clonal complex ET-37/ST-11 as an epidemic clone and the persistence of serogroup A isolates in Burkina Faso. Microbes Infect 2005, 7(4):645-649.
9. Kupferschmidt K. Infectious diseases. Bacterial meningitis finds new niche in gay communities. Science 2013, 341(6144):328.
10. von Gottberg A., du Plessis M., Cohen C., Prentice E., Schrag S., de Gouveia L., et al. Emergence of endemic serogroup W135 meningococcal disease associated with a high mortality rate in South Africa. Clin Infect Dis 2008, 46(3):377-386.
11. Abad R., Lopez E.L., Debbag R., Vazquez J.A. Serogroup W meningococcal disease: global spread and current affect on the Southern Cone in Latin America. Epidemiol Infect 2014, 1-10.
12. Ladhani S.N., Beebeejaun K., Lucidarme J., Campbell H., Gray S., Kaczmarski E., et al. Increase in endemic Neisseria meningitidis capsular group W ST-11 complex associated with severe invasive disease in England and Wales. Clin Infect Dis 2014, 60(4):578-585.
13. Maiden M.C., Bygraves J.A., Feil E., Morelli G., Russell J.E., Urwin R., et al. Multilocus sequence typing: a portable approach to the identification of clones within populations of pathogenic microorganisms. Proc Natl Acad Sci USA 1998, 95(6):3140-3145.
14. Jelfs J., Munro R., Wedege E., Caugant D.A. Sequence variation in the porA gene of a clone of Neisseria meningitidis during epidemic spread. Clin Diagn Lab Immunol 2000, 7(3):390-395.
15. Elias J., Vogel U. IS1301 fingerprint analysis of Neisseria meningitidis strains belonging to the ET-15 clone. J Clin Microbiol 2007, 45(1):159-167.
16. Vogel U., Claus H., Frosch M., Caugant D.A. Molecular basis for distinction of the ET-15 clone within the ET-37 complex of Neisseria meningitidis. J Clin Microbiol 2000, 38(2):941-942.
17. Yamamoto K., Kato Y., Shindo T., Ujiie M., Takeshita N., Kanagawa S., et al. Meningococcemia due to the 2000 Hajj-associated outbreak strain (Serogroup W-135 ST-11) with immunoreactive complications. Jpn J Infect Dis 2013, 66(5):443-445.
18. Bratcher H.B., Corton C., Jolley K.A., Parkhill J., Maiden M.C. A gene-by-gene population genomics platform: de novo assembly, annotation and genealogical analysis of 108 representative Neisseria meningitidis genomes. BMC Genomics 2014, 15:1138.
19. Tsang R.S., Kiefer L., Law D.K., Stoltz J., Shahin R., Brown S., et al. Outbreak of serogroup C meningococcal disease caused by a variant of Neisseria meningitidis serotype 2a ET-15 in a community of men who have sex with men. J Clin Microbiol 2003, 41(9):4411-4414.
20. Veyrier F.J., Hong E., Deghmane A.E., Taha M.K. Draft genome sequence of a Neisseria meningitidis serogroup C isolate of sequence type 11 linked to an outbreak among men who have sex with men. Genome Announc 2013, 1(5).
21. Jolley K.A., Maiden M.C. BIGSdb: scalable analysis of bacterial genome variation at the population level. BMC Bioinformatics 2010, 11:595.
22. Huson D.H. SplitsTree: analyzing and visualizing evolutionary data. Bioinformatics 1998, 14(1):68-73.
23. Read R.C., Baxter D., Chadwick D.R., Faust S.N., Finn A., Gordon S.B., et al. Effect of a quadrivalent meningococcal ACWY glycoconjugate or a serogroup B meningococcal vaccine on meningococcal carriage: an observer-blind, phase 3 randomised clinical trial. Lancet 2014, 384(9960):2123-2131.
24. Budroni S., Siena E., Dunning Hotopp J.C., Seib K.L., Serruto D., Nofroni C., et al. Neisseria meningitidis is structured in clades associated with restriction modification systems that modulate homologous recombination. Proc Natl Acad Sci USA 2011, 108(11):4494-4499.
25. Jolley K.A., Hill D.M., Bratcher H.B., Harrison O.B., Feavers I.M., Parkhill J., et al. Resolution of a meningococcal disease outbreak from whole-genome sequence data with rapid Web-based analysis methods. J Clin Microbiol 2012, 50(9):3046-3053.
26. Lancellotti M., Guiyoule A., Ruckly C., Hong E., Alonso J.M., Taha M.K. Conserved virulence of C to B capsule switched Neisseria meningitidis clinical isolates belonging to ET-37/ST-11 clonal complex. Microbes Infect 2006, 8(1):191-196.
27. Kilic A., Urwin R., Li H., Saracli M.A., Stratton C.W., Tang Y.W. Clonal spread of serogroup W135 meningococcal disease in Turkey. J Clin Microbiol 2006, 44(1):222-224.
28. MenC vaccination schedule: planned changes from June 2013 2013, [accessed 13.04.15]. https://www.gov.uk/government/publications/menc-vaccination-schedule-planned-changes-from-june-2013.
29. O'Ryan M., Stoddard J., Toneatto D., Wassil J., Dull P.M. A multi-component meningococcal serogroup B vaccine (4CMenB): the clinical development program. Drugs 2014, 74(1):15-30.
30. Introduction of MenB vaccination for infants 2015, [accessed 13.04.15]. https://www.gov.uk/government/publications/menb-vaccination-introduction-from-1-september-2015.