Molecular typing of meningococci: Recommendations for target choice and nomenclature

FEMS Microbiology Reviews

Volumn 31, Issue 1, 2007, Pages 89-96

  Jolley, Keith A ^a   Brehony, Carina ^a   Maiden, Martin C J ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Capsule; Diagnosis; Nucleotide sequence; Porin proteins; Serogroup; Serotype

Indexed keywords

FETA PROTEIN; PORB PROTEIN; PORIN A; PROTEIN DERIVATIVE; UNCLASSIFIED DRUG;

ANTIGENIC VARIATION; BACTERIAL GENETICS; BACTERIUM CULTURE; BLOOD GROUP TYPING; DNA SEQUENCE; EPIDEMIC; GENE AMPLIFICATION; GENE LOCUS; GENE TARGETING; MENINGOCOCCOSIS; MOLECULAR DYNAMICS; MOLECULAR TYPING; MULTILOCUS SEQUENCE TYPING; NEISSERIA MENINGITIDIS; NOMENCLATURE; NONHUMAN; REVIEW; VALIDATION PROCESS;

BACTERIAL OUTER MEMBRANE PROTEINS; DNA, BACTERIAL; HUMANS; MENINGOCOCCAL INFECTIONS; NEISSERIA MENINGITIDIS; PORINS; SEQUENCE ANALYSIS, DNA; TERMINOLOGY;

NEISSERIA MENINGITIDIS;

EID: 33846117640     PISSN: 01686445     EISSN: 15746976     Source Type: Journal    
DOI: 10.1111/j.1574-6976.2006.00057.x     Document Type: Review

References (76)

1. Abdillahi H & Poolman JT (1988) Typing of group-B Neisseria meningitidis with monoclonal antibodies in the whole-cell ELISA. J Med Microbiol 26: 177-180.
2. Abdillahi H, Crowe BA, Achtman M & Poolman JT (1988) Two monoclonal antibodies specific for serotype 4 antigen of Neisseria meningitidis. Eur J Clin Microbiol Infect Dis 7: 293-296.
3. Achtman M (1990) Molecular epidemiology of epidemic bacterial meningitis. Rev Med Microbiol 1: 29-38.
4. Achtman M (1996) A surfeit of YATMs? J Clin Microbiol 34: 1870.
5. Achtman M (1997) Microevolution and epidemic spread of serogroup A Neisseria meningitidis - a review. Gene 192: 135-140.
6. Ala'Aldeen DA, Wall RA & Borriello SP (1990) Immunogenicity and cross-reactivity of the 70-Kda iron-regulated protein of Neisseria meningitidis in man and animals. J Med Microbiol 32: 275-281.
7. Altschul SF, Madden TL, Schaffer AA, Zhang J, Zhang Z, Miller W & Lipman DJ (1997) Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucleic Acids Res 25: 3389-3402.
8. Birtles A, Hardy K, Gray SJ, Handford S, Kaczmarski EB, Edwards-Jones V & Fox AJ (2005) Multilocus sequence typing of Neisseria meningitidis directly from clinical samples and application of the method to the investigation of meningococcal disease case clusters. J Clin Microbiol 43: 6007-6014.
9. Bjune G, Høiby EA, Grønnesby JK et al. (1991) Effect of outer membrane vesicle vaccine against group B meningococcal disease in Norway. Lancet 338: 1093-1096.
10. Black JR, Dyer DW, Thompson MK & Sparling PF (1986) Human immune response to iron-repressible outer membrane proteins of Neisseria meningitidis. Infect Immun 54: 710-713.
11. Carson SDB, Klebba PE, Newton SMC & Sparling PF (1999) Ferric enterobactin binding and utilisation by Neisseria gonorrhoeae. J Bacteriol 181: 2895-2901.
12. Caugant DA (1998) Population genetics and molecular epidemiology of Neisseria meningitidis. APMIS 106: 505-525.
13. Caugant DA, Frøholm LO, Bovre K, Holten E, Frasch CE, Mocca LF, Zollinger WD & Selander RK (1987a) Intercontinental spread of Neisseria meningitidis clones of the ET-5 complex. Antonie Leeuwenhoek J Microbiol 53: 389-394.
14. Caugant DA, Mocca LF, Frasch CE, Frøholm LO, Zollinger WD & Selander RK (1987b) Genetic structure of Neisseria meningitidis populations in relation to serogroup, serotype, and outer membrane protein pattern. J Bacteriol 169: 2781-2792.
15. Clarke SC, Diggle MA, Molling P, Unemo M & Olcen P (2003) Analysis of PorA variable region 3 in meningococci: implications for vaccine policy? Vaccine 21: 2468-2473.
16. Derrick JP, Urwin R, Suker J, Feavers IM & Maiden MCJ (1999) Structural and evolutionary inference from molecular variation in Neisseria porins. Infect Immun 67: 2406-2413.
17. Diggle MA & Clarke SC (2002) What a load of old sequence!!!. J Clin Microbiol 40: 2707.
18. Diggle MA, Bell CM & Clarke SC (2003) Nucleotide sequence-based typing of meningococci directly from clinical samples. J Med Microbiol 52: 505-508.
19. Eldridge J, Sutcliffe EM, Abbott JD & Jones DM (1978) Serological grouping of meningococci and detection of antigen in cerebrospinal fluid by coagglutination. Med Lab Sci 35: 63-66.
20. Feavers IM, Heath AB, Bygraves JA & Maiden MC (1992a) Role of horizontal genetic exchange in the antigenic variation of the class 1 outer membrane protein of Neisseria meningitidis. Mol Microbiol 6: 489-495.
21. Feavers IM, Suker J, McKenna AJ, Heath AB & Maiden MCJ (1992b) Molecular analysis of the serotyping antigens of Neisseria meningitidis. Infect Immun 60: 3620-3629.
22. Feavers IM, Fox AJ, Gray S, Jones DM & Maiden MCJ (1996) Antigenic diversity of meningococcal outer membrane protein PorA has implications for epidemiological analysis and vaccine design. Clin Diagn Lab Immunol 3: 444-450.
23. Frasch CE & Chapman S (1972) Classification of Neisseria meningitidis Group B into Distinct Serotypes. Infect Immun 5: 98-102.
24. Frasch CE, Zollinger WD & Poolman JT (1985) Serotype antigens of Neisseria meningitidis and a proposed scheme for designation of serotypes. Rev Infect Dis 7: 504-510.
25. Frasch CE, Tsai C-M & Mocca LF (1986) Outer Membrane Proteins of Neisseria meningitidis: structure and Importance in Meningococcal Disease. Clin Invest Med 9: 101-107.
26. Guiver M & Borrow R (2001) PCR Diagnosis (Pollard AJ & Maiden MCJ, eds), pp. 23-39. Humana Press, Totowa, NJ.
27. Hitchcock PJ (1989) Unified nomenclature for pathogenic Neisseria species. Clin Microbiol Revs 2: S64-S65.
28. Jennings M, Berrington A & Moxon ER (2001) Molecular Analysis of the Meningococcal LPS Expression (Pollard AJ & Maiden MC, eds), pp. 203-214. Humana Press, Totowa.
29. Jodar L, Feavers IM, Salisbury D & Granoff DM (2002) Development of vaccines against meningococcal disease. Lancet 359: 1499-1508.
30. Jolley KA (2001) Multi-Locus Sequence Typing (Pollard AJ & Maiden MC, eds), pp. 173-186. Humana Press, Totowa.
31. Kaczmarski EB (1997) Meningococcal infections in England and Wales. Commun Dis Rep CDR Rev 7: R55-59.
32. Kriz P, Kalmusova J & Felsberg J (2002) Multilocus sequence typing of Neisseria meningitidis directly from cerebrospinal fluid. Epidemiol Infect 128: 157-160.
33. Maiden MCJ (1993) Population genetics of a transformable bacterium: the influence of horizontal genetical exchange on the biology of Neisseria meningitidis. FEMS Microbiol Lett 112: 243-250.
34. Maiden MCJ & Feavers IM (1994) Meningococcal typing. J Med Microbiol 40: 157-158.
35. Maiden MCJ & Frosch M (2001) Molecular techniques for the investigation of meningococcal disease epidemiology. Mol Biotechnol 18: 119-134.
36. Maiden MCJ, Suker J, McKenna AJ, Bygraves JA & Feavers IM (1991) Comparison of the class 1 outer membrane proteins of eight serological reference strains of Neisseria meningitidis. Mol Microbiol 5: 727-736.
37. Maiden MCJ, Bygraves JA, Feil E et al. (1998) Multilocus sequence typing: a portable approach to the identification of clones within populations of pathogenic microorganisms. Proc Natl Acad Sci USA 95: 3140-3145.
38. McGuinness B, Barlow AK, Clarke IN, Farley JE, Anilionis A, Poolman JT & Heckels JE (1990) Deduced amino acid sequences of class 1 protein (PorA) from three strains of Neisseria meningitidis. Synthetic peptides define the epitopes responsible for serosubtype specificity. J Exp Med 171: 1871-1882.
39. McGuinness BT, Lambden PR & Heckels JE (1993) Class 1 outer membrane protein of Neisseria meningitidis: epitope analysis of the antigenic diversity between strains, implications for subtype definition and molecular epidemiology. Mol Microbiol 7: 505-514.
40. Molling P, Unemo M, Backman A & Olcen P (2000) Genosubtyping by sequencing group A, B and C meningococci; a tool for epidemiological studies of epidemics, clusters and sporadic cases. Apmis 108: 509-516.
41. Molling P, Backman A, Olcen P & Fredlund H (2001) Comparison of serogroup W-135 meningococci isolated in Sweden during a 23-year period and those associated with a recent hajj pilgrimage. J Clin Microbiol 39: 2695-2699.
42. Nato F, Mazie JC, Fournier JM, Slizewicz B, Sagot N, Guibourdenche M, Postic D & Riou JY (1991) Production of polyclonal and monoclonal antibodies against group A, B, and C capsular polysaccharides of Neisseria meningitidis and preparation of latex reagents. J Clin Microbiol 29: 1447-1452.
43. Olyhoek T, Crowe BA & Achtman M (1987) Clonal population structure of Neisseria meningitidis serogroup A isolated from epidemics and pandemics between 1915 and 1983. Rev Infect Dis 9: 665-682.
44. Oster P, Lennon D, O'Hallahan J, Mulholland K, Reid S & Martin D (2005) MeNZB: a safe and highly immunogenic tailor-made vaccine against the New Zealand Neisseria meningitidis serogroup B disease epidemic strain. Vaccine 23: 2191-2196.
45. Parkhill J, Achtman M, James KD et al. (2000) Complete DNA sequence of a serogroup A strain of Neisseria meningitidis Z2491. Nature 404: 502-506.
46. Peltola H, Kilpi T & Anttila M (1992) Rapid disappearance of Haemophilus influenzae type b meningitis after routine childhood immunisation with conjugate vaccines. Lancet 340: 592-594.
47. Pettersson A, Kuipers B, Pelzer M, Verhagen E, Tiesjema RH, Tommassen J & Poolman JT (1990) Monoclonal antibodies against the 70-kilodalton iron-regulated protein of Neisseria meningitidis are bactericidal and strain specific. Infect Immun 58: 3036-3041.
48. Pettersson A, Maas A, van Wassenaar D, van der Ley P & Tommassen J (1995) Molecular characterization of FrpB, the 70-kilodalton iron-regulated outer membrane protein of Neisseria meningitidis. Infect Immun 63: 4181-4184.
49. Poolman JT & Abdillahi H (1988) Outer Membrane protein serotyping of Neisseria meningitidis. Eur J Clin Microbiol Infect Dis 7: 291-292.
50. Rouppe van der Voort E, Schuller M, Holst J, de Vries P, van der Ley P, van den Dobbelsteen G & Poolman J (2000) Immunogenicity studies with a genetically engineered hexavalent PorA and a wild-type meningococcal group B outer membrane vesicle vaccine in infant cynomolgus monkeys. Vaccine 18: 1334-1343.
51. Russell JE, Jolley KA, Feavers IM, Maiden MC & Suker JS (2004) PorA variable regions of Neisseria meningitidis. Emerg Infect Dis 10: 674-678.
52. Sacchi CT, Lemos APS, Whitney AM, Solari CA, Brandt ME, Melles CEA, Frasch CE & Mayer LW (1998) Correlation between serological and sequencing analyses of the PorB outer membrane protein in the Neisseria meningitidis serotyping system. Clin Diagn Lab Immunol 5: 348-354.
53. Scholten RJ, Kuipers B, Valkenburg HA, Dankert J, Zollinger WD & Poolman JT (1994) Lipo-oligosaccharide immunotyping of Neisseria meningitidis by a whole-cell ELISA with monoclonal antibodies. J Med Microbiol 41: 236-243.
54. Selander RK, Caugant DA, Ochman H, Musser JM, Gilmour MN & Whittam TS (1986) Methods of multilocus enzyme electrophoresis for bacterial population genetics and systematics. Appl Environ Microbiol 51: 837-884.
55. Sierra GVG, Campa HC, Varcacel NM, Garcia IL, Izquierdo PL, Sotolongo PF, Casanueva GV, Rico CO, Rodriguez CR & Terry MH (1991) Vaccine against group B Neisseria meningitidis: protection trial and mass vaccination results in Cuba. NIPH Ann 14: 195-207.
56. Stuart JM, Monk PN, Lewis DA, Constantine C, Kaczmarski EB & Cartwright KA (1997) Management of clusters of meningococcal disease. PHIS Meningococcus Working Group and Public Health Medicine Environmental Group. Commun Dis Rep CDR Rev 7: R3-5.
57. Suker J, Feavers IM & Maiden MCJ (1996) Monoclonal antibody recognition of members of the P1.10 variable region family: implications for serological typing and vaccine design. Microbiology 142: 63-69.
58. Suker J, Feavers IM, Achtman M, Morelli G, Wang J-F & Maiden MCJ (1994) The porA gene in serogroup A meningococci: evolutionary stability and mechanism of genetic variation. Mol Microbiol 12: 253-265.
59. Taha M-K & Fox A (2006) Quality assessed nonculture techniques for detection and typing of meningococci. FEMS Microbiol Rev 31: DOI: 10.1111/j.1574-6976.2006.00054.x
60. Thompson EAL (2001) Antigenic variation in the potential meningococcal vaccine candidate FetA. DPhil Thesis, Oxford University, UK.
61. Thompson EA, Feavers IM & Maiden MC (2003) Antigenic diversity of meningococcal enterobactin receptor FetA, a vaccine component. Microbiology 149: 1849-1858.
62. Tsai CM, Mocca LF & Frasch CE (1987) Immunotype epitopes of Neisseria meningitidis lipooligosaccharide types 1 through 8. Infect Immun 55: 1652-1656.
63. Unkmeir A, Kammerer U, Stade A, Hubner C, Haller S, Kolb-Maurer A, Frosch M & Dietrich G (2002) Lipooligosaccharide and polysaccharide capsule: virulence factors of Neisseria meningitidis that determine meningococcal interaction with human dendritic cells. Infect Immun 70: 2454-2462.
64. Urwin R (1998) Variation in meningococcal PorB proteins. PhD Thesis, Biological Sciences, Stoke-on-Trent, UK.
65. Urwin R & Maiden MC (2003) Multi-locus sequence typing: a tool for global epidemiology. Trends Microbiol 11: 479-487.
66. Urwin R, Feavers IM, Jones DM, Maiden MCJ & Fox AJ (1998a) Molecular variation of meningococcal serotype 4 antigen genes. Epidemiol Infect 121: 95-101.
67. Urwin R, Fox AJ, Musilek M, Kriz P & Maiden MCJ (1998b) Heterogeneity of the PorB protein in serotype 22 Neisseria meningitidis. J Clin Microbiol 36: 3680-3682.
68. Urwin R, Holmes EC, Fox AJ, Derrick JP & Maiden MC (2002) Phylogenetic evidence for frequent positive selection and recombination in the meningococcal surface antigen PorB. Mol Biol Evol 19: 1686-1694.
69. Urwin R, Russell JE, Thompson EA, Holmes EC, Feavers IM & Maiden MC (2004) Distribution of surface protein variants among hyperinvasive meningococci: implications for vaccine design. Infect Immun 72: 5955-5962.
70. van der Ende A, Hopman CTP, Zaat S, Oude Essink BB, Berkhout B & Dankert J (1995) Variable expression of class 1 outer membrane protein in Neisseria meningitidis is caused by variation in the spacing between the -10 and -35 regions of the promoter. J Bacteriol 177: 2475-2480.
71. van der Ley P, Heckels JE, Virji M, Hoogerhout P & Poolman JT (1991) Topology of outer membrane porins in pathogenic Neisseria species. Infect Immun 59: 2963-2971.
72. van der Ley P, van der Biezen J, Sutmuller R, Hoogerhout P & Poolman JT (1996) Sequence variability of FrpB, a major iron-regulated outer-membrane protein in the pathogenic neisseriae. Microbiology 142: 3269-3274.
73. Vedros NA (1987) Development of Meningococcal Serogroups, Vol. II (Vedros NA, ed), pp. 33-37. CRC Press Inc., Boca Raton, FL.
74. Wang J-F, Caugant DA, Li X, Hu X, Poolman JT, Crowe BA & Achtman M (1992) Clonal and antigenic analysis of serogroup A Neisseria meningitidis with particular reference to epidemiological features of epidemic meningitis in China. Infect Immun 60: 5267-5282.
75. Wedege E, Høiby EA, Rosenqvist E & Bjune G (1998) Immune responses against major outer membrane antigens of Neisseria meningitidis in vaccines and controls who contracted meningococcal disease during the Norwegian serogroup B protection trial. Infect Immun 66: 3223-3231.
76. Zapata GA, Vann WF, Rubinstein Y & Frasch CE (1992) Identification of Variable Region Differences in Neisseria meningitidis Class 3 Protein Sequences Among Five Group B Serotypes. Mol Microbiol 6: 3493-3499.