Nasal carriers are more likely to acquire exogenous Staphylococcus aureus strains than non-carriers

Clinical Microbiology and Infection

Volumn 21, Issue 11, 2015, Pages 998.e1-998.e7

  Ghasemzadeh Moghaddam, H ^a,b   Neela, V ^a   van Wamel, W ^c   Hamat, R A ^a   nor Shamsudin, M ^a   Suhaila Che Hussin, N ^d   Aziz, M N ^d   Mohammad Haspani, M S ^d   Johar, A ^d   Thevarajah, S ^d   Vos, M ^c   van Belkum, A ^c,e  

^a UNIVERSITY PUTRA MALAYSIA   (Malaysia)

^b NORTH KHORASAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c ERASMUS MEDICAL CENTER   (Netherlands)

^d HOSPITAL KUALA LUMPUR   (Malaysia)

^e BIOMÉRIEUX   (France)

Author keywords

Colonization; Colonization interference; MRSA; Nasal carriage; Staphylococcus aureus

Indexed keywords

ADULT; ARTICLE; BACTERIAL COLONIZATION; BACTERIAL STRAIN; BACTERIUM CULTURE; DAY HOSPITAL; FEMALE; FOLLOW UP; HOSPITAL ADMISSION; HOSPITAL HYGIENE; HOSPITAL PATIENT; HOSPITALIZATION; HUMAN; INFECTION CONTROL; INVESTIGATIVE PROCEDURES; MAJOR CLINICAL STUDY; MALE; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; METHICILLIN SUSCEPTIBLE STAPHYLOCOCCUS AUREUS; NEUROSURGERY; NOSE SMEAR; OBSERVATIONAL STUDY; PERSONAL EXPERIENCE; PRIORITY JOURNAL; PROSPECTIVE STUDY; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS INFECTION; ADOLESCENT; AGED; CLASSIFICATION; HETEROZYGOTE; ISOLATION AND PURIFICATION; MICROBIOLOGY; MIDDLE AGED; NOSE MUCOSA; PREVALENCE; STAPHYLOCOCCAL INFECTIONS; VERY ELDERLY; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; CARRIER STATE; FEMALE; FOLLOW-UP STUDIES; HUMANS; MALE; MIDDLE AGED; NASAL MUCOSA; PREVALENCE; PROSPECTIVE STUDIES; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS; YOUNG ADULT;

EID: 84945458550     PISSN: 1198743X     EISSN: 14690691     Source Type: Journal    
DOI: 10.1016/j.cmi.2015.07.006     Document Type: Article

References (36)

1. Schaberg D.R., Culver D.H., Gaynes R.P. Major trends in the microbial etiology of nosocomial infection. Am J Med 1991, 91:S72-S75.
2. Kirkland K.B., Briggs J.P., Trivette S.L., Wilkinson W.E., Sexton D.J. The impact of surgical-site infections in the 1990s: attributable mortality, excess length of hospitalization, and extra costs. Infect Control Hosp Epidemiol 1999, 20:725-730.
3. Van Der Mee-Marquet N., Domelier A.S., Girard N., Quentin R. Epidemiology and typing of Staphylococcus aureus strains isolated from bloodstream infections. J Clin Microbiol 2004, 42:5650-5657.
4. Pittet D., Wenzel R.P. Nosocomial bloodstream infections: secular trends in rates, mortality, and contribution to total hospital deaths. Arch Intern Med 1995 Jun 12, 155(11):1177-1184.
5. Jarvis W.R. Selected aspects of the socioeconomic impact of nosocomial infections: morbidity, mortality, cost, and prevention. Infect Control Hosp Epidemiol 1996, 552-557.
6. Kluytmans J.A., Mouton J.W., VandenBergh M.F., Manders M.J., Maat A.P., Wagenvoort J.H., et al. Reduction of surgical-site infections in cardiothoracic surgery by elimination of nasal carriage of Staphylococcus aureus. Infect Control Hosp Epidemiol 1996, 17(12):780-785.
7. Hollenbeak C.S., Murphy D.M., Koenig S., Woodward R.S., Dunagan W.C., Fraser V.J. The clinical and economic impact of deep chest surgical site infections following coronary artery bypass graft surgery. Chest 2000, 118:397-402.
8. Bode L.G., Kluytmans J.A., Wertheim H.F., Bogaers D., Vandenbroucke-Grauls C.M., Roosendaal R., et al. Preventing surgical-site infections in nasal carriers of Staphylococcus aureus. N Engl J Med 2010, 362:9-17.
9. van Rijen M.M.L., Bode L.G.M., Baak D.A., Kluytmans J.A.J.W., Vos M.C. Reduced costs for Staphylococcus aureus carriers treated prophylactically with mupirocin and chlorhexidine in cardiothoracic and orthopaedic surgery. PloS One 2012, 7:e43065.
10. Williams R.E.O. Healthy carriage of Staphylococcus aureus: its prevalence and importance. Bacteriol Rev 1963, 27:56-71.
11. Corbella X., Domiguez M.A., Pujol M., Ayats J., Sendra M., Pallares R., et al. Staphylococcus aureus nasal carriage as a marker for subsequent staphylococcal infections in intensive care unit patients. Eur J Clin Microbiol Infect Dis 1997, 16:351-357.
12. Lowy F.D. Staphylococcus aureus infections. N Engl J Med 1998, 339:520-532.
13. von Eiff C., Becker K., Machka K., Stammer H., Peters G. Nasal carriage as a source of Staphylococcus aureus bacteremia. N Engl J Med 2001, 344:11-16.
14. Wertheim H.F.L., Vos M.C., Ott A., van Belkum A., Voss A., Kluytmans J.A., et al. Risk and outcome of nosocomial Staphylococcus aureus bacteraemia in nasal carriers versus non-carriers. Lancet 2004, 364:703-705.
15. Boelaert J.R., Van Landuyt H.W., Godard C.A., Daneels R.F., Schurgers M.L., Matthys E.G., et al. Nasal mupirocin ointment decreases the incidence of Staphylococcus aureus bacteraemias in haemodialysis patients. Nephrol Dial Transplant 1993, 8:235-239.
16. Perez-Fontan M., Garcia-Falcon T., Rosales M., Rodríguez-Carmona A., Adeva M., Rodríguez-Lozano I., et al. Treatment of Staphylococcus aureus nasal carriers in continuous ambulatory peritoneal dialysis with mupirocin: long-term results. Am J Kidney Dis 1993 Nov, 22(5):708-712.
17. Kluytmans J.A.J.W., Manders M.J., van Bommel E., Verbrugh H. Elimination of nasal carriage of Staphylococcus aureus in hemodialysis patients. Infect Control Hosp Epidemiol 1996, 793-797.
18. Scully B.E., Briones F., Gu J., Neu H.C. Mupirocin treatment of nasal staphylococcal colonization. Arch Intern Med 1992, 152(2):353-356.
19. Paulson D.S. Efficacy evaluation of a 4% chlorhexidine gluconate as a full-body shower wash. Am J Infect Control 1993, 21:205-209.
20. Fukuta Y., Cunningham C.A., Harris P.L., Wagener M.M., Muder R.R. Identifying the risk factors for hospital-acquired methicillin-resistant Staphylococcus aureus (MRSA) infection among patients colonized with MRSA on admission. Infect Control Hosp Epidemiol 2012, 33:1219-1225.
21. Mostofsky E., Lipsitch M., Regev-Yochay G. Is methicillin-resistant Staphylococcus aureus replacing methicillin-susceptible S. aureus?. J Antimicrob Chemother 2011, 66:2199-2214.
22. Dall'Antonia M., Coen P.G., Wilks M., Whiley A., Millar M. Competition between methicillin sensitive and resistant Staphylococcus aureus in the anterior nares. J Hosp Infect 2005, 61:62-67.
23. Krebes J., Al-Ghusein H., Feasey N., Breathnach A., Lindsay J.A. Are nasal carriers of Staphylococcus aureus more likely to become colonized or infected with methicillin-resistant Staphylococcus aureus on admission to a hospital?. J Clin Microbiol 2011, 49:430-432.
24. Martineau F., Picard F.J., Roy P.H., Ouellette M., Bergeron M.G. Species-specific and ubiquitous-DNA-based assays for rapid identification of Staphylococcus aureus. J Clin Microbiol 1998, 36:618-623.
25. Ghaznavi-Rad E., Shamsudin M.N., Sekawi Z., Van Belkum A., Neela V. A simplified multiplex PCR assay for fast and easy discrimination of globally distributed staphylococcal cassette chromosome mec types in meticillin-resistant Staphylococcus aureus. J Med Microbiol 2010, 59:1135-1139.
26. Shopsin B., Gomez M., Montgomery S.O., Smith D.H., Waddington M., Dodge D.E., et al. Evaluation of protein A gene polymorphic region DNA sequencing for typing of Staphylococcus aureus strains. J Clin Microbiol 1999, 37:3556-3563.
27. Harmsen D., Claus H., Witte W., Rothgänger J., Claus H., Turnwald D., et al. Typing of methicillin-resistant Staphylococcus aureus in a university hospital setting by using novel software for spa repeat determination and database management. J Clin Microbiol 2003, 41:5442-5448.
28. Wertheim H.F.L., Walsh E., Choudhurry R., Melles D.C., Boelens H.A., Miajlovic H., et al. Key role for clumping factor b in Staphylococcus aureus nasal colonization of humans. PLoS Med 2008, 5:e17.
29. Nouwen J., Boelens H., Van Belkum A., Verbrugh H. Human factor in Staphylococcus aureus nasal carriage. Infect Immun 2004, 72:6685-6688.
30. Muthukrishnan G., Lamers R.P., Ellis A., Paramanandam V., Persaud A.B., Tafur S., et al. Longitudinal genetic analyses of Staphylococcus aureus nasal carriage dynamics in a diverse population. BMC Infect Dis 2013, 13:221-2334.
31. Ahmad N. National surveillance on antibiotic resistance: report for 2008 2008, Ministry of Health, Malaysia.
32. Ahmad N., Ruzan I.N., Ghani M.K.A., Hussin A., Nawi S., Aziz M.N., et al. Characteristics of community- and hospital-acquired meticillin-resistant Staphylococcus aureus strains carrying SCCmec type IV isolated in Malaysia. J Med Microbiol 2009, 58:1213-1218.
33. Ghaznavi-Rad E., Shamsudin M.N., Sekawi Z., Khoon L.Y., Aziz M.N., Hamat R.A., et al. Predominance and emergence of clones of hospital-acquired methicillin-resistant Staphylococcus aureus in Malaysia. J Clin Microbiol 2010, 48:867-872.
34. Goering R.V., Shawar R.M., Scangarella N.E., O'Hara F.P., Amrine-Madsen H., West J.M., et al. Molecular epidemiology of methicillin-resistant and methicillin-susceptible Staphylococcus aureus isolates from global clinical trials. J Clin Microbiol 2008, 46:2842-2847.
35. Ghasemzadeh-Moghaddam H., Ghaznavi-Rad E., Sekawi Z., Yun-Khoon L., Aziz M.N., Hamat R.A., et al. Methicillin-susceptible Staphylococcus aureus from clinical and community sources are genetically diverse. Int J Med Microbiol 2011, 301:347-353.
36. Joaquin N.M.Q., Diekema D.J., Perencevich E.N., Bailey G., Winokur P.L., Schweizer M.L. Long-term risk for readmission, methicillin-resistant Staphylococcus aureus (MRSA) infection, and death among MRSA-colonized veterans. Antimicrob Agents Chemother 2013, 57:1169-1172.