Genetic purgatory and the cardiac channelopathies: Exposing the variants of uncertain/unknown significance issue

Heart Rhythm

Volumn 12, Issue 11, 2015, Pages 2325-2331

  Ackerman, Michael J ^a  

^a MAYO CLINIC   (United States)

Author keywords

Brugada syndrome; channelopathies; genetic purgatory; genetic testing; ion channels; long QT syndrome

Indexed keywords

SODIUM CHANNEL NAV1.5;

AGNOSTIC; ARTICLE; ATHEIST; CARDIAC CHANNELOPATHY; CARDIOLOGIST; ELECTROCARDIOGRAM; FAMILY; GENE MUTATION; GENE SEQUENCE; GENETIC PURGATORY; GENETIC SCREENING; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENOTYPE; HUMAN; LONG QT SYNDROME; PHENOTYPE; PRIORITY JOURNAL; SIGNAL NOISE RATIO; VARIANTS OF UNCERTAIN UNKNOWN SIGNIFICANCE; BRUGADA SYNDROME; CHANNELOPATHIES; GENETIC PREDISPOSITION; GENETIC VARIATION; GENETICS; HUMAN GENOME; PROCEDURES; SENSITIVITY AND SPECIFICITY;

BRUGADA SYNDROME; CHANNELOPATHIES; GENETIC PREDISPOSITION TO DISEASE; GENETIC TESTING; GENETIC VARIATION; GENOME, HUMAN; HUMANS; LONG QT SYNDROME; SENSITIVITY AND SPECIFICITY;

EID: 84945453282     PISSN: 15475271     EISSN: 15563871     Source Type: Journal    
DOI: 10.1016/j.hrthm.2015.07.002     Document Type: Article

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