No association between Vitamin D and atopy, asthma, lung function or atopic dermatitis: A prospective study in adults

Allergy: European Journal of Allergy and Clinical Immunology

Volumn 70, Issue 11, 2015, Pages 1501-1504

  Thuesen, B H ^a   Heede, N G ^a,b   Tang, L ^a   Skaaby, T ^a   Thyssen, J P ^b   Friedrich, N ^c   Linneberg, A ^a,d  

^a University of Copenhagen   (Denmark)

^b GENTOFTE UNIVERSITY HOSPITAL   (Denmark)

^c UNIVERSITY MEDICINE GREIFSWALD   (Germany)

^d UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

asthma; atopic dermatitis; epidemiology; IgE; prevention

Indexed keywords

25 HYDROXYVITAMIN D; ALLERGEN; IMMUNOGLOBULIN E; 25-HYDROXYVITAMIN D; FILAGGRIN; INTERMEDIATE FILAMENT PROTEIN; VITAMIN D;

ADULT; ADULT DISEASE; ARTICLE; ASTHMA; ATOPIC DERMATITIS; ATOPY; DISEASE ASSOCIATION; FEMALE; FOLLOW UP; HUMAN; INCIDENCE; LUNG DISEASE; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; PREVALENCE; PRIORITY JOURNAL; PROSPECTIVE STUDY; QUESTIONNAIRE; SPIROMETRY; VITAMIN BLOOD LEVEL; WHEEZING; ANALOGS AND DERIVATIVES; BLOOD; CROSS-SECTIONAL STUDY; DENMARK; DERMATITIS, ATOPIC; GENETICS; GENOTYPE; HEALTH SURVEY; IMMUNOLOGY; LONGITUDINAL STUDY; LUNG FUNCTION TEST; MUTATION; ODDS RATIO; PATHOPHYSIOLOGY; REGISTER;

ADULT; ASTHMA; CROSS-SECTIONAL STUDIES; DENMARK; DERMATITIS, ATOPIC; FEMALE; GENOTYPE; HUMANS; IMMUNOGLOBULIN E; INTERMEDIATE FILAMENT PROTEINS; LONGITUDINAL STUDIES; MALE; MIDDLE AGED; MUTATION; ODDS RATIO; PREVALENCE; PROSPECTIVE STUDIES; PUBLIC HEALTH SURVEILLANCE; REGISTRIES; RESPIRATORY FUNCTION TESTS; VITAMIN D;

EID: 84945438618     PISSN: 01054538     EISSN: 13989995     Source Type: Journal    
DOI: 10.1111/all.12704     Document Type: Article

References (20)

1. Bozzetto S, Carraro S, Giordano G, Boner A, Baraldi E,. Asthma, allergy and respiratory infections: the vitamin D hypothesis. Allergy 2012; 67: 10-17.
2. Wjst M,. The vitamin D slant on allergy. Pediatr Allergy Immunol 2006; 17: 477-483.
3. Wang SS, Hon KL, Kong AP, Pong HN, Wong GW, Leung TF,. Vitamin D deficiency is associated with diagnosis and severity of childhood atopic dermatitis. Pediatr Allergy Immunol 2014; 25: 30-35.
4. Hypponen E, Sovio U, Wjst M, Patel S, Pekkanen J, Hartikainen AL, et al., Infant vitamin D supplementation and allergic conditions in adulthood: northern Finland birth cohort 1966. Ann N Y Acad Sci 2004; 1037: 84-95.
5. Lange NE, Sparrow D, Vokonas P, Litonjua AA,. Vitamin D deficiency, smoking, and lung function in the Normative Aging Study. Am J Respir Crit Care Med 2012; 186: 616-621.
6. Black PN, Scragg R,. Relationship between serum 25-hydroxyvitamin d and pulmonary function in the third national health and nutrition examination survey. Chest 2005; 128: 3792-3798.
7. Thuesen BH, Skaaby T, Husemoen LL, Fenger M, Jorgensen T, Linneberg A,. The association of serum 25-OH vitamin D with atopy, asthma, and lung function in a prospective study of Danish adults. Clin Exp Allergy 2015; 45: 265-272.
8. Thyssen JP, Thuesen B, Huth C, Standl M, Carson CG, Heinrich J, et al., Skin barrier abnormality caused by filaggrin (FLG) mutations is associated with increased serum 25-hydroxy vitamin D concentrations. J Allergy Clin Immunol 2012; 130: 1204-1207.
9. Thyssen JP, Carlsen BC, Menne T, Linneberg A, Nielsen NH, Meldgaard M, et al., Filaggrin null mutations increase the risk and persistence of hand eczema in subjects with atopic dermatitis: results from a general population study. Br J Dermatol 2010; 163: 115-120.
10. Thuesen BH, Cerqueira C, Aadahl M, Ebstrup JF, Toft U, Thyssen JP, et al., Cohort Profile: the Health 2006 cohort, research centre for prevention and health. Int J Epidemiol 2013; 43: 568-575.
11. Horwitz A, Skaaby T, Karhus LL, Schwarz P, Jorgensen T, Rumessen JJ, et al., Screening for celiac disease in Danish adults. Scand J Gastroenterol 2015; 50: 824-831.
12. Williams HC, Burney PG, Pembroke AC, Hay RJ,. The U.K. Working Party's Diagnostic Criteria for Atopic Dermatitis. III. Independent hospital validation. Br J Dermatol 1994; 131: 406-416.
13. Berg ND, Husemoen LL, Thuesen BH, Hersoug LG, Elberling J, Thyssen JP, et al., Interaction between filaggrin null mutations and tobacco smoking in relation to asthma. J Allergy Clin Immunol 2011; 129: 374-380.
14. Miller MR, Hankinson J, Brusasco V, Burgos F, Casaburi R, Coates A, et al., Standardisation of spirometry. Eur Respir J 2005; 26: 319-338.
15. Quanjer PH, Tammeling GJ, Cotes JE, Pedersen OF, Peslin R, Yernault JC,. Lung volumes and forced ventilatory flows. Report Working Party Standardization of Lung Function Tests, European Community for Steel and Coal. Official Statement of the European Respiratory Society. Eur Respir J Suppl 1993; 16: 5-40.
16. Baek JH, Shin YH, Chung IH, Kim HJ, Yoo EG, Yoon JW, et al., The link between serum vitamin D level, sensitization to food allergens, and the severity of atopic dermatitis in infancy. J Pediatr 2014; 165: 849-854.
17. Devereux G, Litonjua AA, Turner SW, Craig LC, McNeill G, Martindale S, et al., Maternal vitamin D intake during pregnancy and early childhood wheezing. Am J Clin Nutr 2007; 85: 853-859.
18. Erkkola M, Kaila M, Nwaru BI, Kronberg-Kippila C, Ahonen S, Nevalainen J, et al., Maternal vitamin D intake during pregnancy is inversely associated with asthma and allergic rhinitis in 5-year-old children. Clin Exp Allergy 2009; 39: 875-882.
19. Hansen S, Maslova E, Strom M, Linneberg A, Halldorsson TI, Granstrom C, et al., The long-term programming effect of maternal 25-hydroxyvitamin D in pregnancy on allergic airway disease and lung function in offspring after 20 to 25 years of follow-up. J Allergy Clin Immunol 2015; 136: 169-176.
20. Mangin M, Sinha R, Fincher K,. Inflammation and vitamin D: the infection connection. Inflamm Res 2014; 63: 803-819.