Part 3: Ethical issues: 2015 American Heart Association guidelines update for cardiopulmonary resuscitation and emergency cardiovascular care

Circulation

Volumn 132, Issue 18, 2015, Pages S383-S396

  Mancini, Mary E ^a   Diekema, Douglas S ^a   Hoadley, Theresa A ^a   Kadlec, Kelly D ^a   Leveille, Marygrace H ^a   McGowan, Jane E ^a   Munkwitz, Michele M ^a   Panchal, Ashish R ^a   Sayre, Michael R ^a   Sinz, Elizabeth H ^a  

^a NONE

Author keywords

Advance directive; DNAR; Life support; Organ donation

Indexed keywords

ADULT; ARTICLE; CHILD; CULTURAL FACTOR; DECISION MAKING; ELECTROENCEPHALOGRAPHY; EMERGENCY CARE; EMERGENCY TREATMENT; ETHICS; EVOKED RESPONSE; GROUPS BY AGE; HEALTH CARE PERSONNEL; HEART ARREST; HUMAN; LEGAL ASPECT; LIFE SUSTAINING TREATMENT; MEDICAL SOCIETY; ORGAN DONOR; OUT OF HOSPITAL CARDIAC ARREST; PATIENT AUTONOMY; PRACTICE GUIDELINE; PREDICTION; PREMATURITY; PRIORITY JOURNAL; PROGNOSIS; RESUSCITATION; RETURN OF SPONTANEOUS CIRCULATION; SCORING SYSTEM; TREATMENT WITHDRAWAL; CANADA; CONSENSUS DEVELOPMENT; EMERGENCY; EMERGENCY HEALTH SERVICE; EXTRACORPOREAL CIRCULATION; INFORMED CONSENT; NEWBORN; OUT-OF-HOSPITAL CARDIAC ARREST; PATIENT ABANDONMENT; PEDIATRICS; PROCEDURES; STANDARDS; UNITED STATES;

ADULT; CANADA; CARDIOPULMONARY RESUSCITATION; CHILD; DECISION MAKING; EMERGENCIES; EMERGENCY MEDICAL SERVICES; EXTRACORPOREAL CIRCULATION; HEART ARREST; HUMANS; INFANT, NEWBORN; INFORMED CONSENT; OUT-OF-HOSPITAL CARDIAC ARREST; PEDIATRICS; REFUSAL TO TREAT; RESUSCITATION ORDERS; THIRD-PARTY CONSENT; UNITED STATES; WITHHOLDING TREATMENT;

EID: 84945315309     PISSN: 00097322     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIR.0000000000000254     Document Type: Article

References (73)

1. Guru V, Verbeek PR, Morrison LJ. Response of paramedics to terminally ill patients with cardiac arrest: an ethical dilemma. CMAJ. 1999;161:1251-1254.
2. Wiese CH, Bartels UE, Zausig YA, Pfrstinger J, Graf BM, Hanekop GG. Prehospital emergency treatment of palliative care patients with cardiac arrest: a retrolective investigation. Support Care Cancer. 2010;18:1287-1292. doi: 10.1007/s00520-009-0746-8.
3. Miller W, Levy P, Lamba S, Zalenski RJ, Compton S. Descriptive analysis of the in-hospital course of patients who initially survive out-of-hospi-tal cardiac arrest but die in-hospital. J Palliat Med. 2010;13:19-22. doi: 10.1089/jpm.2009.0248.
4. Morrison LJ, Kierzek G, Diekema DS, Sayre MR, Silvers SM, Idris AH, Mancini ME. Part 3: ethics: 2010 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. Circulation. 2010;122(suppl 3):S665-S675. doi: 10.1161/CIRCULATIONAHA.110.970905.
5. Beauchamp TL, Childress J. Principles of Biomedical Ethics. Oxford, England: Oxford University Press; 2008.
6. Simon JR. Refusal of care: the physician-patient relationship and deci-sionmaking capacity. Ann Emerg Med. 2007;50:456-461. doi: 10.1016/j. annemergmed.2007.04.016.
7. Hickman SE, Keevern E, Hammes BJ. Use of the physician orders for life-sustaining treatment program in the clinical setting: a systematic review of the literature. J Am Geriatr Soc. 2015;63:341-350. doi: 10.1111/jgs.13248.
8. Avalli L, Maggioni E, Formica F, Redaelli G, Migliari M, Scanziani M, Celotti S, Coppo A, Caruso R, Ristagno G, Fumagalli R. Favourable survival of in-hospital compared to out-of-hospital refractory cardiac arrest patients treated with extracorporeal membrane oxygenation: an Italian tertiary care centre experience. Resuscitation. 2012;83:579-583. doi: 10.1016/j.resuscitation.2011.10.013.
9. Wolf MJ, Kanter KR, Kirshbom PM, Kogon BE, Wagoner SF. Extracorporeal cardiopulmonary resuscitation for pediatric cardiac patients. Ann Thorac Surg. 2012;94:874-879; discussion 879. doi: 10.1016/j.athoracsur.2012.04.040.
10. Delmo Walter EM, Alexi-Meskishvili V, Huebler M, Redlin M, Boettcher W, Weng Y, Berger F, Hetzer R. Rescue extracorporeal membrane oxy-genation in children with refractory cardiac arrest. Interact Cardiovasc Thorac Surg. 2011;12:929-934. doi: 10.1510/icvts.2010.254193.
11. Maekawa K, Tanno K, Hase M, Mori K, Asai Y. Extracorporeal cardiopulmonary resuscitation for patients with out-of-hospital cardiac arrest of cardiac origin: a propensity-matched study and predictor analysis. Crit Care Med. 2013;41:1186-1196. doi: 10.1097/CCM.0b013e31827ca4c8.
12. Sakamoto T, Morimura N, Nagao K, Asai Y, Yokota H, Nara S, Hase M, Tahara Y, Atsumi T; SAVE-J Study Group. Extracorporeal cardio-pulmonary resuscitation versus conventional cardiopulmonary resuscitation in adults with out-of-hospital cardiac arrest: a prospective observational study. Resuscitation. 2014;85:762-768. doi: 10.1016/j. resuscitation.2014.01.031.
13. Atkins DL, Everson-Stewart S, Sears GK, Daya M, Osmond MH, Warden CR, Berg RA; Resuscitation Outcomes Consortium Investigators. Epidemiology and outcomes from out-of-hospital cardiac arrest in children: the Resuscitation Outcomes Consortium Epistry-Cardiac Arrest. Circulation. 2009;119:1484-1491. doi: 10.1161/CIRCULATIONAHA.108.802678.
14. Kitamura T, Iwami T, Kawamura T, Nagao K, Tanaka H, Nadkarni VM, Berg RA, Hiraide A; implementation working group for All-Japan Utstein Registry of the Fire and Disaster Management Agency. Conventional and chest-compression-only cardiopulmonary resuscitation by bystanders for children who have out-of-hospital cardiac arrests: a prospective, nationwide, population-based cohort study. Lancet. 2010;375:1347-1354. doi: 10.1016/S0140-6736(10)60064-5.
15. Young KD, Gausche-Hill M, McClung CD, Lewis RJ. A prospective, population-based study of the epidemiology and outcome of out-of-hospital pediatric cardiopulmonary arrest. Pediatrics. 2004;114:157-164.
16. Moler FW, Donaldson AE, Meert K, Brilli RJ, Nadkarni V, Shaffner DH, Schleien CL, Clark RS, Dalton HJ, Statler K, Tieves KS, Hackbarth R, Pretzlaff R, van der Jagt EW, Pineda J, Hernan L, Dean JM; Pediatric Emergency Care Applied Research Network. Multicenter cohort study of out-of-hospital pediatric cardiac arrest. Crit Care Med. 2011;39:141-149. doi: 10.1097/CCM.0b013e3181fa3c17.
17. López-Herce J, García C, Domínguez P, Rodríguez-Núñez A, Carrillo A, Calvo C, Delgado MA; Spanish Study Group of Cardiopulmonary Arrest in Children. Outcome of out-of-hospital cardiorespiratory arrest in children. Pediatr Emerg Care. 2005;21:807-815.
18. Field JM, Hazinski MF, Sayre MR, Chameides L, Schexnayder SM, Hemphill R, Samson RA, Kattwinkel J, Berg RA, Bhanji F, Cave DM, Jauch EC, Kudenchuk PJ, Neumar RW, Peberdy MA, Perlman JM, Sinz E, Travers AH, Berg MD, Billi JE, Eigel B, Hickey RW, Kleinman ME, Link MS, Morrison LJ, O'Connor RE, Shuster M, Callaway CW, Cucchiara B, Ferguson JD, Rea TD, Vanden Hoek TL. Part 1: executive summary: 2010 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. Circulation. 2010;122(suppl 3):S640-S656. doi: 10.1161/CIRCULATIONAHA.110.970889.
19. Bottoms SF, Paul RH, Mercer BM, MacPherson CA, Caritis SN, Moawad AH, Van Dorsten JP, Hauth JC, Thurnau GR, Miodovnik M, Meis PM, Roberts JM, McNellis D, Iams JD. Obstetric determinants of neonatal survival: antenatal predictors of neonatal survival and morbidity in extremely low birth weight infants. Am J Obstet Gynecol. 1999;180(3 pt 1):665-669.
20. Ambalavanan N, Carlo WA, Bobashev G, Mathias E, Liu B, Poole K, Fanaroff AA, Stoll BJ, Ehrenkranz R, Wright LL; National Institute of Child Health and Human Development Neonatal Research Network. Prediction of death for extremely low birth weight neonates. Pediatrics. 2005;116:1367-1373. doi: 10.1542/peds.2004-2099.
21. Manktelow BN, Seaton SE, Field DJ, Draper ES. Population-based estimates of in-unit survival for very preterm infants. Pediatrics. 2013;131:e425-e432. doi: 10.1542/peds.2012-2189.
22. Medlock S, Ravelli AC, Tamminga P, Mol BW, Abu-Hanna A. Prediction of mortality in very premature infants: a systematic review of prediction models. PLoS One. 2011;6:e23441. doi: 10.1371/journal.pone.0023441.
23. Patel H, Beeby PJ. Resuscitation beyond 10 minutes of term babies born without signs of life. J Paediatr Child Health. 2004;40:136-138.
24. Tyson JE, Parikh NA, Langer J, Green C, Higgins RD; National Institute of Child Health and Human Development Neonatal Research Network. Intensive care for extreme prematurity-moving beyond gestational age. N Engl J Med. 2008;358:1672-1681. doi: 10.1056/NEJMoa073059.
25. Casalaz DM, Marlow N, Speidel BD. Outcome of resuscitation following unexpected apparent stillbirth. Arch Dis Child Fetal Neonatal Ed. 1998;78:F112-F115.
26. Harrington DJ, Redman CW, Moulden M, Greenwood CE. The long-term outcome in surviving infants with Apgar zero at 10 minutes: a systematic review of the literature and hospital-based cohort. Am J Obstet Gynecol. 2007;196:463.e1-463.e5. doi: 10.1016/j.ajog.2006.10.877.
27. Kasdorf E, Laptook A, Azzopardi D, Jacobs S, Perlman JM. Improving infant outcome with a 10 min Apgar of 0. Arch Dis Child Fetal Neonatal Ed. 2015;100:F102-F105. doi: 10.1136/archdischild-2014-306687.
28. Laptook AR, Shankaran S, Ambalavanan N, Carlo WA, McDonald SA, Higgins RD, Das A; Hypothermia Subcommittee of the NICHD Neonatal Research Network. Outcome of term infants using apgar scores at 10 minutes following hypoxic-ischemic encephalopathy. Pediatrics. 2009;124:1619-1626. doi: 10.1542/peds.2009-0934.
29. Sarkar S, Bhagat I, Dechert RE, Barks JD. Predicting death despite therapeutic hypothermia in infants with hypoxic-ischaemic encephalopathy. Arch Dis Child Fetal Neonatal Ed. 2010;95:F423-F428. doi: 10.1136/adc.2010.182725.
30. Chen YS, Lin JW, Yu HY, Ko WJ, Jerng JS, Chang WT, Chen WJ, Huang SC, Chi NH, Wang CH, Chen LC, Tsai PR, Wang SS, Hwang JJ, Lin FY. Cardiopulmonary resuscitation with assisted extracorporeal life-support versus conventional cardiopulmonary resuscitation in adults with in-hospital cardiac arrest: an observational study and propensity analysis. Lancet. 2008;372:554-561. doi: 10.1016/S0140-6736(08)60958-7.
31. Lin JW, Wang MJ, Yu HY, Wang CH, Chang WT, Jerng JS, Huang SC, Chou NK, Chi NH, Ko WJ, Wang YC, Wang SS, Hwang JJ, Lin FY, Chen YS. Comparing the survival between extracorporeal rescue and conventional resuscitation in adult in-hospital cardiac arrests: propensity analysis of three-year data. Resuscitation. 2010;81:796-803. doi: 10.1016/j. resuscitation.2010.03.002.
32. Shin TG, Choi JH, Jo IJ, Sim MS, Song HG, Jeong YK, Song YB, Hahn JY, Choi SH, Gwon HC, Jeon ES, Sung K, Kim WS, Lee YT. Extracorporeal cardiopulmonary resuscitation in patients with inhospital cardiac arrest: A comparison with conventional cardiopulmonary resuscitation. Crit Care Med. 2011;39:1-7. doi: 10.1097/CCM.0b013e3181feb339.
33. Wu ET, Li MJ, Huang SC, Wang CC, Liu YP, Lu FL, Ko WJ, Wang MJ, Wang JK, Wu MH. Survey of outcome of CPR in pediatric in-hospital cardiac arrest in a medical center in Taiwan. Resuscitation. 2009;80:443-448. doi: 10.1016/j.resuscitation.2009.01.006.
34. Moler FW, Meert K, Donaldson AE, Nadkarni V, Brilli RJ, Dalton HJ, Clark RS, Shaffner DH, Schleien CL, Statler K, Tieves KS, Hackbarth R, Pretzlaff R, van der Jagt EW, Levy F, Hernan L, Silverstein FS, Dean JM; Pediatric Emergency Care Applied Research Network. In-hospital versus out-of-hospital pediatric cardiac arrest: a multicenter cohort study. Crit Care Med. 2009;37:2259-2267. doi: 10.1097/CCM.0b013e3181a00a6a.
35. de Mos N, van Litsenburg RR, McCrindle B, Bohn DJ, Parshuram CS. Pediatric in-intensive-care-unit cardiac arrest: incidence, survival, and predictive factors. Crit Care Med. 2006;34:1209-1215. doi: 10.1097/01. CCM.0000208440.66756.C2.
36. Lowry AW, Morales DL, Graves DE, Knudson JD, Shamszad P, Mott AR, Cabrera AG, Rossano JW. Characterization of extracorporeal membrane oxygenation for pediatric cardiac arrest in the United States: analysis of the kids' inpatient database. Pediatr Cardiol. 2013;34:1422-1430. doi: 10.1007/s00246-013-0666-8.
37. Odegard KC, Bergersen L, Thiagarajan R, Clark L, Shukla A, Wypij D, Laussen PC. The frequency of cardiac arrests in patients with congenital heart disease undergoing cardiac catheterization. Anesth Analg. 2014;118:175-182. doi: 10.1213/ANE.0b013e3182908bcb.
38. Ortmann L, Prodhan P, Gossett J, Schexnayder S, Berg R, Nadkarni V, Bhutta A; American Heart Association's Get With the Guidelines-Resuscitation Investigators. Outcomes after in-hospital cardiac arrest in children with cardiac disease: a report from Get With the Guidelines-Resuscitation. Circulation. 2011;124:2329-2337. doi: 10.1161/CIRCULATIONAHA.110.013466.
39. Matos RI, Watson RS, Nadkarni VM, Huang HH, Berg RA, Meaney PA, Carroll CL, Berens RJ, Praestgaard A, Weissfeld L, Spinella PC; American Heart Association's Get With The Guidelines-Resuscitation (Formerly the National Registry of Cardiopulmonary Resuscitation) Investigators. Duration of cardiopulmonary resuscitation and illness category impact survival and neurologic outcomes for in-hospital pedi-atric cardiac arrests. Circulation. 2013;127:442-451. doi: 10.1161/CIRCULATIONAHA.112.125625.
40. Reis AG, Nadkarni V, Perondi MB, Grisi S, Berg RA. A prospective investigation into the epidemiology of in-hospital pediatric cardiopulmonary resuscitation using the international Utstein reporting style. Pediatrics. 2002;109:200-209.
41. Haque A, Rizvi A, Bano S. Outcome of in-hospital pediatric cardio-pulmonary arrest from a single center in Pakistan. Indian J Pediatr. 2011;78:1356-1360. doi: 10.1007/s12098-011-0439-4.
42. Meert KL, Donaldson A, Nadkarni V, Tieves KS, Schleien CL, Brilli RJ, Clark RS, Shaffner DH, Levy F, Statler K, Dalton HJ, van der Jagt EW, Hackbarth R, Pretzlaff R, Hernan L, Dean JM, Moler FW; Pediatric Emergency Care Applied Research Network. Multicenter cohort study of in-hospital pediatric cardiac arrest. Pediatr Crit Care Med. 2009;10:544-553. doi: 10.1097/PCC.0b013e3181a7045c.
43. López-Herce J, Del Castillo J, Matamoros M, Cañadas S, Rodriguez-Calvo A, Cecchetti C, Rodriguez-Núñez A, Alvarez AC; Iberoamerican Pediatric Cardiac Arrest Study Network RIBEPCI. Factors associated with mortality in pediatric in-hospital cardiac arrest: a prospective multicenter multinational observational study. Intensive Care Med. 2013;39:309-318. doi: 10.1007/s00134-012-2709-7.
44. Tibballs J, Kinney S. A prospective study of outcome of in-patient pae-diatric cardiopulmonary arrest. Resuscitation. 2006;71:310-318. doi: 10.1016/j.resuscitation.2006.05.009.
45. Ahrens T, Schallom L, Bettorf K, Ellner S, Hurt G, O'Mara V, Ludwig J, George W, Marino T, Shannon W. End-tidal carbon dioxide measurements as a prognostic indicator of outcome in cardiac arrest. Am J Crit Care. 2001;10:391-398.
46. Callaham M, Barton C. Prediction of outcome of cardiopulmonary resuscitation from end-tidal carbon dioxide concentration. Crit Care Med. 1990;18:358-362.
47. Cantineau JP, Lambert Y, Merckx P, Reynaud P, Porte F, Bertrand C, Duvaldestin P. End-tidal carbon dioxide during cardiopulmonary resuscitation in humans presenting mostly with asystole: a predictor of outcome. Crit Care Med. 1996;24:791-796.
48. Levine RL, Wayne MA, Miller CC. End-tidal carbon dioxide and outcome of out-of-hospital cardiac arrest. N Engl J Med. 1997;337:301-306. doi: 10.1056/NEJM199707313370503.
49. Wayne MA, Levine RL, Miller CC. Use of end-tidal carbon dioxide to predict outcome in prehospital cardiac arrest. Ann Emerg Med. 1995;25:762-767.
50. Kessler SK, Topjian AA, Gutierrez-Colina AM, Ichord RN, Donnelly M, Nadkarni VM, Berg RA, Dlugos DJ, Clancy RR, Abend NS. Short-term outcome prediction by electroencephalographic features in children treated with therapeutic hypothermia after cardiac arrest. Neurocrit Care. 2011;14:37-43. doi: 10.1007/s12028-010-9450-2.
51. Nishisaki A, Sullivan J 3rd, Steger B, Bayer CR, Dlugos D, Lin R, Ichord R, Helfaer MA, Nadkarni V. Retrospective analysis of the prognostic value of electroencephalography patterns obtained in pediatric in-hospital cardiac arrest survivors during three years. Pediatr Crit Care Med. 2007;8:10-17. doi: 10.1097/01.pcc.0000256621.63135.4b.
52. Abend NS, Topjian AA, Kessler SK, Gutierrez-Colina AM, Berg RA, Nadkarni V, Dlugos DJ, Clancy RR, Ichord RN. Outcome prediction by motor and pupillary responses in children treated with therapeutic hypothermia after cardiac arrest. Pediatr Crit Care Med. 2012;13:32-38. doi: 10.1097/PCC.0b013e3182196a7b.
53. Fink EL, Berger RP, Clark RS, Watson RS, Angus DC, Richichi R, Panigrahy A, Callaway CW, Bell MJ, Kochanek PM. Serum biomarkers of brain injury to classify outcome after pediatric cardiac arrest. Crit Care Med. 2014;42:664-674. doi: 10.1097/01.ccm.0000435668.53188.80.
54. Topjian AA, Lin R, Morris MC, Ichord R, Drott H, Bayer CR, Helfaer MA, Nadkarni V. Neuron-specifc enolase and S-100B are associated with neurologic outcome after pediatric cardiac arrest. Pediatr Crit Care Med. 2009;10:479-490. doi: 10.1097/PCC.0b013e318198bdb5.
55. Topjian AA, Clark AE, Casper TC, Berger JT, Schleien CL, Dean JM, Moler FW; Pediatric Emergency Care Applied Research Network. Early lactate elevations following resuscitation from pediatric cardiac arrest are associated with increased mortality. Pediatr Crit Care Med. 2013;14:e380-e387. doi: 10.1097/PCC.0b013e3182976402.
56. Peberdy MA, Ornato JP. Post-resuscitation care: is it the missing link in the Chain of Survival? Resuscitation. 2005;64:135-137. doi: 10.1016/j. resuscitation.2004.09.015.
57. Sandroni C, Cariou A, Cavallaro F, Cronberg T, Friberg H, Hoedemaekers C, Horn J, Nolan JP, Rossetti AO, Soar J. Prognostication in comatose survivors of cardiac arrest: an advisory statement from the European Resuscitation Council and the European Society of Intensive Care Medicine. Resuscitation. 2014;85:1779-1789. doi: 10.1016/j. resuscitation.2014.08.011.
58. Tiainen M, Kovala TT, Takkunen OS, Roine RO. Somatosensory and brainstem auditory evoked potentials in cardiac arrest patients treated with hypothermia. Crit Care Med. 2005;33:1736-1740.
59. Kottenberg-Assenmacher E, Armbruster W, Bornfeld N, Peters J. Hypothermia does not alter somatosensory evoked potential amplitude and global cerebral oxygen extraction during marked sodium nitroprus-side-induced arterial hypotension. Anesthesiology. 2003;98:1112-1118.
60. Greer D, Scripko P, Bartscher J, Sims J, Camargo E, Singhal A, Parides M, Furie K. Clinical MRI interpretation for outcome prediction in cardiac arrest. Neurocrit Care. 2012;17:240-244. doi: 10.1007/s12028-012-9716-y.
61. Orioles A, Morrison WE, Rossano JW, Shore PM, Hasz RD, Martiner AC, Berg RA, Nadkarni VM. An under-recognized beneft of cardiopulmonary resuscitation: organ transplantation. Crit Care Med. 2013;41:2794-2799. doi: 10.1097/CCM.0b013e31829a7202.
62. Matsumoto CS, Kaufman SS, Girlanda R, Little CM, Rekhtman Y, Raof V, Laurin JM, Shetty K, Fennelly EM, Johnson LB, Fishbein TM. Utilization of donors who have suffered cardiopulmonary arrest and resuscitation in intestinal transplantation. Transplantation. 2008;86:941-946. doi: 10.1097/TP.0b013e3181852f9a.
63. Asher J, Navarro A, Watson J, Wilson C, Robson L, Gupta A, Gok M, Balupuri S, Shenton B, Del Rio Martin J, Sen B, Jaques B, Soomro N, Rix D, Manas D, Talbot D. Does donor cardiopulmonary resuscitation time affect outcome in uncontrolled non-heart-beating donor renal transplants? Transplant Proc. 2005;37:3264-3265. doi: 10.1016/j. transproceed.2005.09.006.
64. Reynolds JC, Rittenberger JC, Callaway CW; Post Cardiac Arrest Service. Patterns of organ donation among resuscitated patients at a regional cardiac arrest center. Resuscitation. 2014;85:248-252. doi: 10.1016/j. resuscitation.2013.11.001.
65. Peberdy MA, Callaway CW, Neumar RW, Geocadin RG, Zimmerman JL, Donnino M, Gabrielli A, Silvers SM, Zaritsky AL, Merchant R, Vanden Hoek TL, Kronick SL; American Heart Association. Part 9: post-cardiac arrest care: 2010 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. Circulation. 2010;122(suppl 3):S768-S786. doi: 10.1161/CIRCULATIONAHA.110.971002.
66. Bernat JL. Point: are donors after circulatory death really dead, and does it matter? Yes and yes. Chest. 2010;138:13-16. doi: 10.1378/chest.10-0649.
67. Bernat JL, Capron AM, Bleck TP, Blosser S, Bratton SL, Childress JF, DeVita MA, Fulda GJ, Gries CJ, Mathur M, Nakagawa TA, Rushton CH, Shemie SD, White DB. The circulatory-respiratory determination of death in organ donation. Crit Care Med. 2010;38:963-970. doi: 10.1097/CCM.0b013e3181c58916.
68. Committee on Hospital Care SoS, Section on Critical C. Policy state-ment?pediatric organ donation and transplantation. Pediatrics. 2010;125:822-828.
69. Gries CJ, White DB, Truog RD, Dubois J, Cosio CC, Dhanani S, Chan KM, Corris P, Dark J, Fulda G, Glazier AK, Higgins R, Love R, Mason DP, Nakagawa TA, Shapiro R, Shemie S, Tracy MF, Travaline JM, Valapour M, West L, Zaas D, Halpern SD; American Thoracic Society Health Policy Committee. An offcial American Thoracic Society/International Society for Heart and Lung Transplantation/Society of Critical Care Medicine/Association of Organ and Procurement Organizations/United Network of Organ Sharing Statement: ethical and policy considerations in organ donation after circulatory determination of death. Am J Respir Crit Care Med. 2013;188:103-109. doi: 10.1164/rccm.201304-0714ST.
70. Hornby K, Hornby L, Shemie SD. A systematic review of autoresus-citation after cardiac arrest. Crit Care Med. 2010;38:1246-1253. doi: 10.1097/CCM.0b013e3181d8caaa.
71. Joffe AR, Carcillo J, Anton N, deCaen A, Han YY, Bell MJ, Maffei FA, Sullivan J, Thomas J, Garcia-Guerra G. Donation after cardiocircula-tory death: a call for a moratorium pending full public disclosure and fully informed consent. Philos Ethics Humanit Med. 2011;6:17. doi: 10.1186/1747-5341-6-17.
72. Nakagawa TA, Rigby MR, Bratton S, Shemie S, Ajizian SJ, Berkowitz I, Bowens CD, Cosio CC, Curley MA, Dhanani S, Dobyns E, Easterling L, Fortenberry JD, Helfaer MA, Kolovos NS, Koogler T, Lebovitz DJ, Michelson K, Morrison W, Naim MY, Needle J, Nelson B, Rotta AT, Rowin ME, Serrao K, Shore PM, Smith S, Thompson AE, Vohra A, Weise K. A call for full public disclosure for donation after circulatory determination of death in children. Pediatr Crit Care Med. 2011;12:375-377; author reply 377. doi: 10.1097/PCC.0b013e31820ac30c.
73. Truog RD, Miller FG. Counterpoint: are donors after circulatory death really dead, and does it matter? No and not really. Chest. 2010;138:16-18; discussion 18. doi: 10.1378/chest.10-0657.